A.

INHIBITORIAISINTEZEIPERETELUICELULAR
I.INHIBASINTEZAPEPTIDOGLICANULUI
Denumirea

Exemple

Spectrubantibacterian

Desemisinteza

PENICILINE

Debiosinteza

Benzilpenicilina
Fenoximetilpenicilina
CGP,BGP,CGN,Bacteriianaerobe
Benzatinpenicilina
Procainpenicilina
Meticilina
peniciline
Oxacilina
rezistentela
Stafilocociproducatoridepenicilinaza.
penicilinaza
Nafcilina
stafilococica
Cloxacilina
(grupM)
Dicloxacilina
CGP,BGP,CGN,Bacteriianaerobe,BGN(Haemophilus,Escherichia,
Ampicilina
aminopeniciline
Salmonella,Shigella,Proteus )
Amoxicilina
grupA
Bacampicilina
Carboxipeniciline:
carbenicilina
ticarcilina
CGP,BGP,CGN,Bacteriianaerobe,BGN(Haemophilus,Escherichia,
penicilinecu
Ureidopeniciline:
Salmonella,Shigella,Proteus,Enterobacter,Klebsiella,Serratia,
spectrulargit
azlocilina,
Pseudomonas)
piperacilina
mezlocilina
ampicilina+sulbactam
amoxicilina+acid
peniciline
Staphylococcus,Neisseriagonorhhoeae,Moraxellacatarrhalis,
clavulanic
asociatecu
Haemophilus,Escherichiacoli,Klebsiella,Shigella,Salmonella,
ticarcilina+acid
inhibitoride
Bateroidesfragilis
clavulanic
betalactamaze
piperacilina+tazobactam

GeneratiaII
GeneratiaIII

CEFALOSPORINE

GeneratiaI

Antibioticebetalactamice

parenteral cefalotina
cefapirina
cefazolina
orale cefalexina
cefradin
cefadroxil
parenteral
cefuroxima
cefamadol
ceforanid
Cefalosporine cefunocid
propriuzise:
orale cefaclor
cefuroximaaxetil
cefprozil
cefoxitina
Cefamicine
cefotetan
(parenterale
cefmetazol
parenteral cefotaxima
ceftizoxima
ceftriaxona
ceftazidima
cefoperazona
orale cefpodoximaaxetil
cefixima
ceftibutena

GeneratiaIV

cefepima
cefpiroma

CGP,BGP,CGN,BGN(Escherichia,Salmonella,Shigella,Proteus,
Klebsiella),stafilocociproducatoridepenicilinaza

CGP,BGP,CGN,BGN(Escherichia,Salmonella,Shigella,Proteus,
Klebsiella,Haemophilus,Enterobacter,Serratia),stafilococi
producatoridepenicilinaza

CGP,BGP,CGN,BGN(Escherichia,Salmonella,Shigella,Proteus,
Klebsiella,Haemophilus,Enterobacter,Serratia),stafilococi
producatoridepenicilinaza,bacteriianaerobe

CGP,BGP,CGN,BGN(Escherichia,Salmonella,Shigella,Proteus,
Klebsiella,Haemophilus,Enterobacter,Serratia),stafilococi
producatoridepenicilinaza,bacteriianaerobe,Pseudomonas
aeruginosa (ceftazidima+cefoperazon)

CGP,BGP,CGN,BGN(Escherichia,Salmonella,Shigella,Proteus,Klebsiella,
Haemophilus,Enterobacter,Serratia,Pseudomonasaeruginosa),stafilococi
producatoridepenicilinaza,bacteriianaerobe

imipenem+cilastatin
CARBAPENEME

meropenem

bacteriiGPsiGN,aerobesianaerobe,inactivefatade
Mycobacterium,Mycoplasma,Chlamydia,Rickettsia

ertapenem
MONOBACTAM
GLICOPEPTIDE

aztreonam

BGN(fam.Enterobacteriaceae ,genulPseudomonas

vancomicina

bacteriiGP,aerobesianaerobe;ininfectiicuStaphylococcus
meticilinorezistent,Streptococcuspneumoniae,Enterococcus
multirezistentelaantibiotice
bacteriiaerobeGPsiGN,stafilococimeticilinorezistenti,
enterococi

teicoplanina
FOSFOMICINA
II.Antibioticecareinhibasintezaacizilor izoniazida
micolicisauarabinogalactanuldin
pirazinamida
structurapereteluicelularla
Mycobacterium
etambutol

baciliituberculozei
baciliituberculozeisicomplexulMycobacteriumavium
intercellulare