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Drug Reconstitution
Dosage Conversion
There are several formulas used to calculate drug doges: Only one
formula is necessary to calculate any medication. Choose the formula
easiest for you to Use.
.
Desired Dose x
Dose on Hand
B.
Dose on Hand
Volume on Hand
"
Volume of Drug
on Hand
Volume of Desired
Dose (X)
,
desired
Volume Desired (X)
Desired
Dose on Dose
Hand
2.
3.
Lasix comes 10 mg/lcc. The order is for 22 mg, how many cc's would you
administer?
4.
The Ampicillin final concentration is 250 mg/5 cc. What volume do you give for
a dose of 400 mg IV?
16
5.
Gentamicin is available in the concentration of 40 mg/1 cc. How many cc's do you
need to give 6 mg.dose?
6.
From an ampule labeled codeine 15 mg/0.5 cc, give 4 mg. How many cc's do you
need?
".
8.
9.
Compazine vial is 25 mg/2cc concentration. How many ccs do you give for a dose
of 12.5 mg?
Heparin is available in the concentration of 6,000 U/0.3 ccs. The physician order is
for 10,000 units. How many cc's do you give?
10.
Phenobarbital is available as 130 mg/cc. The physician order is 270 mg. How
many cc's do you give? .
11.
The physician order is for 1.2 mg of Atropine and the vial is 10mg/ccs. How
many cc's would you administer?
'
A chi1d has an order for 2 mg. Valium IV prior to an invasive procedure. The
vial of Valium is 5 mg . How many cc's would you administer?
14. Vancomycin 150 mg is ordered for a child and' the reconstituted volume is 500
mg/10 cc. How many ccs would you administer?
17
.n_
....
_____A
.'
..
15.
'16.
Tobramycin 30 mg is ordered and the vial is 40 mg/cc. How many cc's would
you administer?
Narcan 0.1 mg is ordered for a child in the emergency room and the vial is 20
mcg. How many cc's
. . would you administer?
17.
Vistaril 1.5 mg. is being given postoperatively and the vial is 25 mg/cc. How
many cc's would you administer?
18. Solu-Medrol 24 mg. is being given; the vial is 40 mg/cc. How many cc's would
you administer?
.
19. Demerol 15 mg is being given as a one time' pre-procedural drug 'and the vial is'
25 mg/cc. How many ccs would you administer?
20. Cefataxime 300 mg. is ordered and you have reconstituted one gram of cefotaxime with
9.8 cc of sterile Water yielding a concentration of 1 gram/10 cc. How many cc's will
you administer?
18
CALCUlATIONS
Medication Dosage Based on Bodv Weight/Dose
Medication Dosage Based on Bodv Weight/ Dav
The nurse must also chccsk if the ordered dosage is within a safe range for the child. This
can be calculated on a drug range' given/day or a drug range given/dose. First determine
the pediatric dosage range/kilogram of medication .from the Drug Reference
I.
I.
n.
Usual dose of Demerol is 1-2 mg/kg/dose pm. What would the maximum dose
for a 15 kg. child be for Demerol?
3.
AminophylIine usual dose is 4-6 mg/kg/dose every six hours. What is the
maximum dose for a 4 kg infant for one dose?
19
---
4.
Lasix usual dose is 1-6 mg/kg/dose. The physician ordered 2 mg/kg every 12 hours.
How much is needed for a 12 kg child for one dose?
5.
Cefotaxime dose for children is 100-200 mg/kg/day q 6-8 hours. What is the
maximum daily amount of Cefotaxime for a 44 kg child? What is the maximum
dose if given Q 8 hours?
6.
Decadron is being given for airway edema. The dosage is 0.25 -0.5 mg/kg/dose.
What is the maximum dose for a 18 kilogram child?
7.
Reglan is being given to increase stomach emptying. The range for infants is
0.05 - 0.1 mg/kg/dose. What is the maximum and minimum dose for a 6 kg.
infant ?
8.
Phenobarbital is being given for Status Epilepticus ~Dosing 5-10 mg/kg/dose. What
is the maximum dose for a 34 kg. child?
9.
10.
Ampicillin is ordered for a child. The safe range is 100 - 400 mg/kg/day Q 4-6
hours. What is the maximum daily dose for a 25 kg. child? What is the dose
Q 6 hours?
.
.'
11.
12.
13.
14.
Cimetidine is ordered for a 36 kg child using the range of 20-40 mg/kg/day Q 6 hours.
What is the maximum daily dose for this child? What is the maximum dose' if given Q
12 hours?
.. 20
..
. ... ....
- - -.--------.______________~
-_. ..-
1.
0.75 mcg
2.
13.3 cc
3.
2.2 cc
4.
8.0 cc
5.
0.15 cc
6.
0.13 cc
7.
1.0 cc
8.
0.5 cc
9.
2.5 cc
10. 2.1 cc
11. 0.12 cc
12. 2.8 cc
13. 0.4 cc
14. 3.0 cc
I5. 0.75 cc
16. 5 mcg
.17. 0.06 cc
18. 0.6 cc
19. 0.6 cc
20. 3.0 cc
1.
2.
3.
4.
5.
6:7.
8.
9.
10.
11.
12.
13.
14.
20 mg Q8h
30 mg
24 mg
24 mg
a. 8.8 grams
b. 2.9 grams
9 mg
0.3mg minimum
0.6 mg maximum
340 mg .
15 grams
a. 10 gms/day
b. 2.5 gmsQ6h
a. 800 mg/day
b. 200 mg q6h
3.6 mg
0.16 mg
a. 1,440 mg/day
b. 720 mg q 12