Вы находитесь на странице: 1из 5

University Of Santo Tomas

College of Nursing
DRUG ANALYSIS
Name: Daryll Joyce S. Romero
Section: 2-NUR-7
RLE 7.2
Generic
Name
ORS

Penicillin

January 20, 2015

Brand Name

Mechanism of Action

Indication

Contraindications

Side effect

dioralyte,
dioalyte
relief,
electrolade

ORS preserves
facilitated glucosesodium cotransport
system in the smallbowel mucosa.
Glucose is absorbed
by the intestine and
there is a greater
absorption of isotonic
salt solution. Glucose
absorption system
usually remains intact
during diarrheal
illnesses, net
absorption of water
and electrolytes
solution can equal or
exceed diarrheal stool
volume even if the
loss is rapid.
Triggering of the
pneumococcal
autolytic enzyme by
inhibitors of cell wall
synthesis

Diarrhea and
electrolyte depletion

Hyporeninemic,
Complete Heart
Block, Chronic
Heart Failure,
Intestinal Ulcer,
Stomach or
Intestine Blockage,
Serious Kidney
Problems, Serious
Loose Stools
Lasting a Long
Time, Decreased
Amount of Urine,
High Amount of
Potassium in the
Blood, Paralysis

Mild vomiting,
Hypernatremia
(dizziness, fast
heart, high blood
pressure,
irritability, muscle
twitching,
restlessness,
seizure, swelling of
feet or lower legs,
weakness)

Puffy eyelids

Hypersensitivity
and solutions
containing dextrose
may be
contraindicated in
patients with
known allergy to
corn products.

Black tongue, sore


throat, nausea,
vomiting, severe
diarrhea, fever and
swollen joints.

Cardiac arrest or
arrhythmias
with high doses,
headache,
neurotoxicity
(seizures, coma,
hyperreflexia),
Diaphoresis,
blurred vision,

pfizerpen,
penicillin G
procaine,
penicillin G
sodium,
penicillin G
benzanthine,
bicillin L-A,
crystapen

Treatment of mild to
moderate upper
respiratory tract
infections, venereal
diseases, moderately
severe infections by
microorganisms that
are sensitive to low
and persistent serum

Adverse Effect

Nursing
Responsibilities
Assess vital signs
Monitor intake and
output and observe
properties of urine
Provide oral care
Administer
medications as
prescribed

Instruct the patient


to finish course of
therapy.
Instruct penicillin
allergic patient to
carry medical
identification.
Inform patient of
signs of

levels. It was also a


treatment of anthrax.

intestinal
nephritis,
hypersensitivity

Amoxicillin

Mebendazol
e

amoxil,
amoxial
pediatric
drops, apoamoxi
(CAN),
dispermox,
novamoxin
(CAN), Nuamoxi(CAN),
trimox

Antibiotic (penicillinampicillin type),


Bactericidal which
inhibits synthesis of
cell wall of sensitive
organisms, causing
cell death

Infections due to
susceptible strains of
haemophilus
influenza, E.coli,
Neisseria gonorrhea,
streptococcus
pneumonia,
enterococcus
faecalis,
streptococci, non
penicillinase.

Liver Problems,
Blockage of
Normal Bile Flow,
Serious Kidney
Problems,
Clostridium
Difficile Bacteria
Related Colitis

Nausea, vomiting
or diarrhea, dark
urine, breathing
problems, allergic
reactions like skin
rash, itching,
swelling of face,
lips or tongue

Loose bowel
movements

vermox

Irreversibly blocks
glucose uptake by
susceptible
helminthes, depleting
glycogen stores
needed for survival
and reproduction of
helminthes, depleting
glycogen stores
needed for survival
and reproduction of
helminthes causing
death.

Treatment of
microorganisms
such as whipworm,
pinworm,
roundworm,
common hookworm,
american hookworm

Liver problems and


allergic reactions to
benzimidazoles

Abdominal pain,
vomiting, diarrhea,
headache, dizziness
or drowsiness,

Transient
abdominal pain,
diarrhea, fever

hypersensitivity
(skin rash, itching,
shortness of breath,
wheezing) and other
side effects.
Instruct patient to
notify health care
provider if there is
no improvement
and if there is signs
of superinfection
Note for
hypersensitivity
reaction
Monitor CBC, renal
and liver function
tests.
Instruct clients that
therapeutic
regimenmust be
completed even if
symptoms subside.
Assess for
pregnancy, lactation
and allergy,
temperature, bowel
sounds and output.
Arrange for second
course of treatment
if patient is not
cured 3 weeks after
treatment.
Administer drug
with food, tablets
maybe chewed,
swallowed or
crushed.

Ferrous
Sulfate
(FeSO4)

Cotrimoxazo
le

Rifampicin

feosol, fer
iron, fer gen,
feratab,
frosul, ferraTD, slow fe,
fer-gen-sol,
fer-in-sol

septra,
bactrim,
septrin

rifadin,
rimactane

Elevates the serum


iron concentration
which then helps to
form high or trapped
in the
reticuloendothelial
cells for storage and
eventual conversion to
a usable form or iron.

Prevention and
treatment of iron
deficiency anemias.
Dietary supplement
for iron.

Inhibits synthesis of
nucleic acids and
proteins in susceptible
bacteria. The bacterial
enzyme involved in tis
reaction is more
readily inhibited than
the mammalian
enzyme.

Uncomplicated
UTIs caused by
susceptible strains of
microorganisms and
treatment of acute
otitis media.

Act as an antibiotic,
antituberculotic which
is considered as a first
line of defense. It also
inhibits DNAdependent RNA
polymerase activity in
susceptible bacterial
cells

Treatment of
pulmonary
Tuberculosis,
Infections caused by
microorganisms and
Neisseria
miningitidis carriers
for asymptomatic
carriers.

Ulcer,
Inflammation of
the Lining of the
Stomach and
Intestines, Several
Blood
Transfusions, Iron
Metabolism,
Increased Bodily
Iron from High Red
Blood Cell
Destruction,
Hemolytic Anemia

Constipaion, black
stools, temporary
staining of the
teeth, upset
stomach

Hypersensitivity to
sulphonamides,
pregnancy,
advanced liver and
renal
insufficiencies.

Rash, pruritus,
fever, epigastric
distress

Dizzines, Nasal
congestion,
dyspnea,
hypotension,
Muscle cramps,
flushing

Reversible
exanthemas,
loss of appetite,
nausea,
vomiting, and
diarrhea.

Yellowing of Skin
or Eyes from Liver
Problems, Liver
Problems,
Diabetes,
Porphyria, Habit of
Drinking Too Much
Alcohol

Red colored
secretions

Hepatotoxicity,
pruritus, rash
nausea,
vomiting, chills
fever, malaise

Advise patient to
take medicine as
prescribed
Advise patient to
consult physician if
irregular hearbeat,
dyspnea, swelling
of hands nd feet and
hypotension occurs
Encourage patient
for proper diet,
regular exercise,
lifestyle changes
and stress
management.
Perform culture and
sensitivity tests
before the therapy.
Protect from
exposure of light
Arrange for periodic
blood counts during
therapy
Discontinue drug
and consult with
physician if any
significant
reduction in any
formed blood
element occurs
Administer an
empty stomach 1
hour before or 2
hours after meals
Prepare patient for
reddish-orange
coloring of body
fluids
Instruc client to

Isoniazid

niazid

Treats active
tuberculosis infections
to prevent further
symptoms of
tuberculosis. Interferes
with lipid and nucleic
acid biosynthesis in
actively growing
tubercle bacilli.

Tuberculosis of all
forms, prophylaxis
in specific patients
who are tuberculin
reactors or who are
considered to be
high risk for TB.

Numbness,
Tingling or Pain of
Hands or Feet, ,
Acute Liver
Failure, Serious
Kidney Problems,
Severe Nausea and
Vomiting that has
Lasted a Long
Time, Under
Control diabetes,
Poor Nutrition,
Anemia, Gout,

Peripheral
neuropathy, nausea
and vomiting, local
irritation at IM
site., epigastric
distress

Pyrazinamid
e

Ethambutol

Loss of appetite,
Nausea,
Vomiting,
Stomach pain,
Weakness,
Slurred speech,
Lethargy,
hyperreflexia,
anemia, seizure

remove contact
lenses as they may
discolor
Tell client to see
physician if he
experienced fever,
chills, muscle and
bone pain
Give an empty
stomach 1 hour
before or 2 after
meals
Given in single
daily use
Have a periodic
medical check ups
Report for weakness,
fatigue, loss of appetite,
yellowing of skin or
eyes

Fever, dysuria,
hepatotoxicity,
thrombocytopen
ia, mild
arthralgia and
myalgia,
hypersensitivity
including
rashes, urticarial
and pruritis.
myambutol,
servambutol

Ethambutol is a
bacteriostatic against
actively growing TB
bacilli; it works by
obstructing the
formation of cell wall.

Eliminates certain
bacteria that cause
tuberculosis. It is
used with other
medicines to teat
tuberculosis and to

Cataracts, Sudden
Blindness and Pain
Upon Moving the
Eye, Kidney
Disease, Retinal
Changes of Eye in

Loss of appetite,
upset stomach,
vomiting,
numbness and
tingling in the
hands nor feet,

Anaphylaxis,
Anorexia,
Confusion,
disorientation,
Fever,

Assess patient for


infection at
beginning and
during therapy
Obtain specimens
before initiating

It disrupts
arabinogalactan
synthesis by inhibiting
the enzyme arabinosyl
transferase.

prevent you from


giving the infection
to others.

a Patient with
Diabetes, Gout

optic neuritisblurring of vision

Headache,
Malaise, Nausea

Strepthomyc
in

biolab
streptomycin
sulfate,

Inhibits CHON
synthesis strains of
gram ngative bacteria,
mechanisms of lethal
action and fully
understood, but
functional integrity of
cell membrane appears
to be disrupted.

Infections caused by
susceptible strain of
mycobacterium
tuberculosis. Serious
infections caused by
susceptible strains of
Yersinia Pestis

Parkinson
Symptoms, Inner
Ear Disturbance,
Damage of Nerve
that Controls
Hearing and
Balance, Kidney
Disease, Sensation
of Spinning or
Whirling,
Pregnancy, Food
Poisoning of Infant,
Low Amount of
Calcium in the
Blood, Extreme
Loss of Body Water

Abnormal skin
sensation round the
face, feeling of
whirling motion,
fever, swelling

Severe allergic
reactions
(dyspnea,
swelling of
mouth, face, lips
or tongue),
decrease
urination,
hearing loss,
muscle
weakness, skin
rash or itching,
ringing or
roaring in the
ears

therapy
Not to be given to
children 6 years
below due to optic
neuritis
Provide
supplemental
vitamin A if not
contraindicated
Use in route only:
given by deep IM
injection
Ensure adequate
hydration of patient
before and during
therapy
Monitor for hearing
changes
Report hearing
changes, dizziness,
pain at injection
site, rash