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Immunostimulation
in aquatic animals
by Philippe Tacon, global aquaculture manager, Phileo
FEATURE
products with similar manna/
glucan ratios from Phileo, Lesaffre
Table 1: Formulation and compositions of experimental diets (%).
Animal Care Business Unit, have
Ingredients
very different effects in the
stimulation of immune parameters
Fishmeal 38.5
25
25
25
25
25
and in survival following challenge
Soybean protein concentrate
20
20
20
20
20
20
in Vibrio anguillarum. It looks like
Soybean meal
0
21
21
21
21
21
not only the mannan and glucan
Wheat flour
21
21
21
21
21
21
content is of importance, but the
strain and the drying processes
Fish oil
6
6.4
6.4
6.4
6.4
6.4
are also key parameters to ensure
Monocalcium
1
2.1
2.1
2.1
2.1
2.1
a good effect in aquatic animals.
phosphate(Ca(H2PO4)2)
Another concept that came out
Microcrystalline cellulose 10.1
1
0.975
0.95
0.9
0.8
of these trials was that there is a
Phospholipid (93%)
2
2
2
2
2
2
threshold of yeast material to be
Choline chloride(50%) 0.4
0.4
0.4
0.4
0.4
0.4
ingested before it starts to kick in
and improve the immune system.
Vitamin and mineral Premixa
1
1
1
1
1
1
Product origin, quality, dosages
Methionine hydroxy analog-Ca(98%)
0
0.1
0.1
0.1
0.1
0.1
and duration of treatment are all
Safmannan (mg/kg)
0
0
250
500
1000
2000
clearly linked.
Analyzed chemical compositions(dry matter basis %)
A trial has been undertaken to
further study a dose response of
Crude protein 47.6
48.2
48.7
47.9
48.4
48.5
Safmannan in a marine species.
Crude lipid 12.1
12.0
11.7
11.6
11.8
11.6
The objective was twofold:
Crude ash 7.86
8.51
8.46
8.52
8.59
8.41
investigate the influence of
parietal fractions in diets with a
Gross energy(MJ/kg) 21.5
21.3
21.4
21.5
21.4
21.6
reduced amount of fishmeal, and
determine the dosage needed for
diets were supplemented with 0 (SBM), 250, 500, 1000 and 2000
an optimum immune response (Yu et al 2014).
Six diets were designed (see table 1): a high fishmeal diet with g/T of Safmannan. Juvenile Japanese seabass (18 g) were selected
38.5 percent fish meal inclusion and no soybean meal (HFM) and 5 and distributed into 280 L tanks after 24 h starvation with 30 fish
diets with 25 percent fishmeal and 20 percent soybean meal. These per tank, and six tanks per treatment. The water temperature was
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FEATURE
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