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E. F.
Age
24 y.o
Height
52
Diagnosis
Sex
Female
Weight
55 kg
Author
M. M. Olmillo
Website
milkv.co.vu
A/N
youre welcome J
DRUG DATA
Generic name:
Tramadol Hcl
CLASSIFICATION
Pharmacologic:
Opioid analgesic
Trade name/s:
Ryzolt, Ultram
Patients dose:
500mg q 6o
Minimum dose:
25mg/day
MECHANISM OF
ACTION
Binds to mu-opioid
receptors and inhibits
the reuptake of
norepinephrine and
serotonin
Therapeutic:
Centrally-acting
analgesic
Pregnancy
Category Risk: C
Onset:
1 hr
Peak:
2 hr
Maximum dose:
500mg/day
Metabolism:
Hepatic; 6-7 hr
Availability:
Tablets: 50mg
ER tablets: 100,
200, 300 mg
Distribution:
Crosses placenta,
enters breast milk
Excretion: urine
Route:
IVTT
Source: 2011
Lippincotts NDG
Source: 2011
Lippincotts NDG
Source: 2011
Lippincotts NDG
INDICATIONS
General:
> relief of
moderate to
moderately
severe pain
> relief of
moderate to
severe chronic
pain in adults who
need around-theclock treatment
for extended
periods (ER
tablets)
> unlabeled uses:
premature
ejaculation;
restless leg
syndrome
Patients actual
indication:
> relief of
moderate to
moderately
severe pain
Source: 2011
Lippincotts NDG
CONTRAINDICATI
ON
Contraindicated with
allergy to tramadol or
opioids or acute
intoxication with alcohol,
oipioids or psychoactive
drugs
ADVERSE
EFFECTS
CNS: asterixis,
dizziness,
weakness,
headache,
drowsiness
CV: orthostatic
hypotension
Precaution:
Use cautiously with
pregnancy, lactation,
seizures, concomitant
use of CNS depressants,
MAOIs, SSRIs, TCAs,
renal impairment,
hepatic impairment
GI: nausea,
anorexia, vomiting,
diarrhea
Interactions:
Drug-drug: decreased
effectiveness with
carbamazepine,
increased risk of
tramadol toxicity with
MAOIs or SSRIs.
Local: pain,
phlebitis at
injection site
Source: 2011
Lippincotts NDG
Source: 2011
Lippincotts NDG
GU: polyuria,
nocturia
Hematologic:
hypokalemia
Other: muscle
cramps and
muscle spasms,
weakness, arthritic
pain
NURSING
RESPONSIBILITIE
S
Before:
> check the doctors order.
> assess for hypersensitivity to
tramadol, pregnancy, lactation,
seizures
>assess for skin color, texture,
lesions, mental status, take V/S
> check for the patency of the IV line
> review the purpose and importance
of the drug
During:
> administer with food or milk to
prevent GI upset
> measure and record regular
weights to monitor fluid changes
> administer drug early in the day so
increased urination will not disturb
sleep
> control environment (temperature,
lighting) if sweating or CNS effects
occur
After:
> document and record.
> monitor serum electrolytes,
hydration, and liver function during
long-term therapy
> provide diet rich in potassium or
give supplemental potassium
>report if side effects occur.