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ABSORPTION OF CARBOHYDRATES
Absorption by the Intestinal Epithelium
> Brush border of the small intestine
> Monosaccharides require transporters
in order to be transported across the
intestinal epithelial cells.
Na+-Dependent Transporters (SGLT)
> Na+-dependent glucose transporters,
which are located on the luminal side of
the absorptive cells, enable these cells to
concentrate glucose from the intestinal
lumen.
low intracellular Na+ concentration is
maintained by a Na+K+-ATPase on the
serosal (blood) side of the cell that uses
the energy from ATP cleavage to pump
Na+ out of the cell into the blood
transport of glucose from a low
concentration in the lumen to a high
concentration in the cell is promoted by
the co-transport of Na+ from a high
concentration in the lumen to a low
concentration in the cell (secondary
active transport)
Facilitative Glucose Transporters
Action of Insulin