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Rheumatoid Hands
Pathological Features of RA
Pathological Features of RA
Pathological Features of RA
IgM antibody
surfaces
Rheumatoid Nodules
Clinical Features of RA
Clinical Features of RA
Clinical Features of RA
General Symptoms
Early
morning stiffness
Weight loss
Fever
Malaise
Fatigue
Local Symptoms
Joint
Pain
swelling
Clinical Features of RA
Signs
Tenderness
Redness
local heat
Swelling
boggy to palpation
Clinical Features of RA
Signs Hips
Disability
Rheumatoid
Extra-articular Manifestations
Eye
Scleritis
Lungs
Pulmonary
Effusions
Pulmonary Fibrosis assoc with high RF titre
Extra-articular Manifestations
CVS
Pericardial
effusions, pericarditis
Urinary tract
Amyloidosis
CNS
Primary
neuropathy
Cervical myelopathy 2 subluxation of C-Spine
Investigations
Radiological Features
Juxta-articular osteoporosis
Marginal erosions
Deformity
Hands
Treatment - Medical
NSAIDs
Second Line Tx
Gold salts, penicillamine, immunosuppressants
(azothioprine)
Known as the DMARDs
Third Line Tx
Corticosteroids (prednisolone) lowest dose to
control symptoms and minimize side effects
Intra-articular steroids may be utilised in accessible
joints
Treatment - Surgical
be perfomed arthroscopically
Advanced disease
Joint
knee
Joint
Hip Arthrodesis