Академический Документы
Профессиональный Документы
Культура Документы
Cardiovascular system
The circulatory system, also called the cardiovascular system, is an organ system that permits blood to
circulate and transport nutrients (such as amino acids
and electrolytes), oxygen, carbon dioxide, hormones, and
blood cells to and from the cells in the body to provide
nourishment and help in ghting diseases, stabilize temperature and pH, and maintain homeostasis. The study of
the blood ow is called hemodynamics. The study of the
properties of the blood ow is called hemorheology.
The circulatory system is often seen to comprise both the
cardiovascular system, which distributes blood, and the
lymphatic system, which circulates lymph.[1] These are Depiction of the heart, major veins and arteries contwo separate systems. The passage of lymph for exam- structed from body scans.
ple takes a lot longer than that of blood.[2] Blood is a
uid consisting of plasma, red blood cells, white blood
cells, and platelets that is circulated by the heart through
the vertebrate vascular system, carrying oxygen and nutrients to and waste materials away from all body tissues.
Lymph is essentially recycled excess blood plasma after it
has been ltered from the interstitial uid (between cells)
and returned to the lymphatic system. The cardiovascular (from Latin words meaning 'heart' and 'vessel') system comprises the blood, heart, and blood vessels.[3] The
lymph, lymph nodes, and lymph vessels form the lymphatic system, which returns ltered blood plasma from
the interstitial uid (between cells) as lymph.
While humans, as well as other vertebrates, have a closed
cardiovascular system (meaning that the blood never
leaves the network of arteries, veins and capillaries), some
invertebrate groups have an open cardiovascular system.
The lymphatic system, on the other hand, is an open system providing an accessory route for excess interstitial
uid to be returned to the blood.[4] The more primitive,
diploblastic animal phyla lack circulatory systems.
Structure
1 STRUCTURE
ing that the blood never leaves the network of blood ves- 1.1.6 Heart
sels. In contrast, oxygen and nutrients diuse across the
blood vessel layers and enter interstitial uid, which car- Main article: Heart
ries oxygen and nutrients to the target cells, and carbon The heart pumps oxygenated blood to the body and
dioxide and wastes in the opposite direction. The other
component of the circulatory system, the lymphatic sysSuperior
Vena Cava
tem, is open.
1.1.1
Aorta
Arteries
Pulmonary
Artery
Pulmonary
Vein
Capillaries
Right
Atrium
Left
Atrium
Mitral
Valve
Left
Ventricle
Pulmonary
Valve
Tricuspid
Valve
Aortic
Valve
Right
Ventricle
Arteries branch into small passages called arterioles and View from the front
then into the capillaries.[8] The capillaries merge to bring
blood into the venous system.[9]
deoxygenated blood to the lungs. In the human heart
there is one atrium and one ventricle for each circulation, and with both a systemic and a pulmonary circula1.1.3 Veins
tion there are four chambers in total: left atrium, left venAfter their passage through body tissues, capillaries tricle, right atrium and right ventricle. The right atrium
merge once again into venules, which continue to merge is the upper chamber of the right side of the heart. The
into veins. The venous system nally coalesces into blood that is returned to the right atrium is deoxygenated
two major veins: the superior vena cava (roughly speak- (poor in oxygen) and passed into the right ventricle to
ing draining the areas above the heart) and the inferior be pumped through the pulmonary artery to the lungs for
vena cava (roughly speaking from areas below the heart). re-oxygenation and removal of carbon dioxide. The left
These two great vessels empty into the right atrium of the atrium receives newly oxygenated blood from the lungs
as well as the pulmonary vein which is passed into the
heart.
strong left ventricle to be pumped through the aorta to
the dierent organs of the body.
1.1.4 Coronary vessels
The coronary circulation system provides a blood supply
to the heart muscle itself. The coronary circulation beMain article: Coronary circulation
gins near the origin of the aorta by two arteries: the right
coronary artery and the left coronary artery. After nourThe heart itself is supplied with oxygen and nutrients ishing the heart muscle, blood returns through the corothrough a small loop of the systemic circulation.
nary veins into the coronary sinus and from this one into
the right atrium. Back ow of blood through its opening
during atrial systole is prevented by the Thebesian valve.
1.1.5 Portal veins
The smallest cardiac veins drain directly into the heart
[7]
The general rule is that arteries from the heart branch out chambers.
into capillaries, which collect into veins leading back to
the heart. Portal veins are a slight exception to this. In
humans the only signicant example is the hepatic portal vein which combines from capillaries around the gut
where the blood absorbs the various products of digestion; rather than leading directly back to the heart, the
hepatic portal vein branches into a second capillary system in the liver.
1.2
Lymphatic system
3
1.1.10 Kidneys
The renal circulation receives around 20% of the cardiac
output. It branches from the abdominal aorta and returns
blood to the ascending vena cava. It is the blood supply to
the kidneys, and contains many specialized blood vessels.
Physiology
A separate system known as the bronchial circulation supplies blood to the tissue of the larger airways of the lung.
1.1.8
Systemic circulation
An animation of a typical human red blood cell cycle in the circulatory system. This animation occurs at real time (20 seconds of
cycle) and shows the red blood cell deform as it enters capillaries,
as well as changing color as it alternates in states of oxygenation
along the circulatory system.
Brain
3 CLINICAL SIGNIFICANCE
2.1
Arterial development
Another major cardiovascular disease involves the creation of a clot, called a thrombus. These can originate in veins or arteries. Deep venous thrombosis, which
mostly occurs in the legs, is one cause of clots in the veins
of the legs, particularly when a person has been stationary
for a long time. These clots may embolise, meaning travel
The dorsal aortae, present on the dorsal side of the em- to another location in the body. The results of this may
bryo, are initially present on both sides of the embryo. include pulmonary embolus, transient ischaemic attacks,
They later fuse to form the basis for the aorta itself. Ap- or stroke.
proximately thirty smaller arteries branch from this at the
back and sides. These branches form the intercostal arter- Cardiovascular diseases may also be congenital in nature,
ies, arteries of the arms and legs, lumbar arteries and the such as heart defects or persistent fetal circulation, where
lateral sacral arteries. Branches to the sides of the aorta the circulatory changes that are supposed to happen after
will form the denitive renal, suprarenal and gonadal ar- birth do not. Not all congenital changes to the circulatory
teries. Finally, branches at the front of the aorta consist of system are associated with diseases, a large number are
the vitelline arteries and umbilical arteries. The vitelline anatomical variations.
arteries form the celiac, superior and inferior mesenteric
arteries of the gastrointestinal tract. After birth, the um3.2 Measurement techniques
bilical arteries will form the internal iliac arteries.
2.2
Venous development
Clinical signicance
Many diseases aect the circulatory system. This includes cardiovascular disease, aecting the cardiovascular system, and lymphatic disease aecting the lymphatic
system. Cardiologists are medical professionals which
specialise in the heart, and cardiothoracic surgeons specialise in operating on the heart and its surrounding areas.
Vascular surgeons focus on other parts of the circulatory
Magnetic resonance angiography of aberrant subclavian artery
system.
5
The function and health of the circulatory system and 5
its parts are measured in a variety of manual and automated ways. These include simple methods such as those
5.1
that are part of the cardiovascular examination, including
the taking of a persons pulse as an indicator of a persons heart rate, the taking of blood pressure through a
sphygmomanometer or the use of a stethoscope to listen
to the heart for murmurs which may indicate problems
with the hearts valves. An electrocardiogram can also be
used to evaluate the way in which electricity is conducted
through the heart.
Other more invasive means can also be used. A cannula
or catheter inserted into an artery may be used to measure
pulse pressure or pulmonary wedge pressures. Angiography, which involves injecting a dye into an artery to visualise an arterial tree, can be used in the heart (coronary
angiography) or brain. At the same time as the arteries are
visualised, blockages or narrowings may be xed through
the insertion of stents, and active bleeds may be managed
by the insertion of coils. An MRI may be used to image
arteries, called an MRI angiogram. For evaluation of the
blood supply to the lungs a CT pulmonary angiogram may
be used.
Ultrasound can also be used, particularly to identify the
health of blood vessels, and a Doppler ultrasound of the
carotid arteries or Doppler ultrasound of the lower limbs
can be used to evaluate for narrowing of the carotid arteries or thrombus formation in the legs, respectively.
3.3
Surgery
Other animals
Other vertebrates
Two-chambered heart of a sh
There are a number of surgical procedures performed on In reptiles, the ventricular septum of the heart is incomplete and the pulmonary artery is equipped with a
the circulatory system:
sphincter muscle. This allows a second possible route
of blood ow. Instead of blood owing through the pul Coronary artery bypass surgery
monary artery to the lungs, the sphincter may be contracted to divert this blood ow through the incomplete
Coronary stent used in angioplasty
ventricular septum into the left ventricle and out through
the aorta. This means the blood ows from the capillar Vascular surgery
ies to the heart and back to the capillaries instead of to
the lungs. This process is useful to ectothermic (cold Vein stripping
blooded) animals in the regulation of their body temperature.
Cosmetic procedures
Birds and mammals show complete separation of the
heart into two pumps, for a total of four heart chambers; it
Cardiovascular procedures are more likely to performed is thought that the four-chambered heart of birds evolved
in the inpatient setting than in an ambulatory care setting; independently from that of mammals.
in the United States, only 28% of cardiovascular surgeries
were performed in the ambulatory care setting.[11]
6
tion between blood and interstitial uid; this combined
uid is called hemolymph or haemolymph.[12] Muscular
movements by the animal during locomotion can facilitate hemolymph movement, but diverting ow from one
area to another is limited. When the heart relaxes, blood
is drawn back toward the heart through open-ended pores
(ostia).
Hemolymph lls all of the interior hemocoel of the body
and surrounds all cells. Hemolymph is composed of
water, inorganic salts (mostly Na+ , Cl , K+ , Mg2+ , and
Ca2+ ), and organic compounds (mostly carbohydrates,
proteins, and lipids). The primary oxygen transporter
molecule is hemocyanin.
HISTORY
6 History
Above is a diagram of an open circulatory system. An open circulatory system is made up of a heart, vessels, and hemolymph.
This diagram shows how the hemolymph, uid present in most invertebrates that is equivalent to blood, is circulated throughout the
body of a grasshopper. The hymolymph is rst pumped through
the heart, into the aorta, dispersed into the head and throughout
the hemocoel, then back through the ostium that are located in
the heart, where the process is repeated.
7
The earliest known writings on the circulatory system
are found in the Ebers Papyrus (16th century BCE), an
ancient Egyptian medical papyrus containing over 700
prescriptions and remedies, both physical and spiritual.
In the papyrus, it acknowledges the connection of the
heart to the arteries. The Egyptians thought air came in
through the mouth and into the lungs and heart. From
the heart, the air travelled to every member through the
arteries. Although this concept of the circulatory system
is only partially correct, it represents one of the earliest
accounts of scientic thought.
circulation in his Treatise on Pulse.[15] While also rening Galens erroneous theory of the pulse, Avicenna
provided the rst correct explanation of pulsation: Every beat of the pulse comprises two movements and two
pauses. Thus, expansion : pause : contraction : pause.
[...] The pulse is a movement in the heart and arteries ... which takes the form of alternate expansion and
contraction.[16]
REFERENCES
See also
Cardiology
Vital heat
Cardiac muscle
Major systems of the human body
Amato Lusitano
References
[21] Pormann, Peter E. and Smith, E. Savage (2007) Medieval Islamic medicine Georgetown University, Washington DC, p. 48, ISBN 1589011619.
[22] The Nobel Prize in Physiology or Medicine 1956. Nobel Foundation. Retrieved 2007-07-28.
External links
http://cnx.org/content/m46646/latest/
The Circulatory System
Reiber C. L. & McGaw I. J. (2009). A Review
of the Open and Closed Circulatory Systems:
New Terminology for Complex Invertebrate Circulatory Systems in Light of Current Findings.
International Journal of Zoology 2009: 8 pages.
doi:10.1155/2009/301284.
Patwardhan K. The history of the discovery of
blood circulation: unrecognized contributions of
Ayurveda masters. Adv Physiol Educ. 2012
Jun;36(2):7782.
Michael Servetus Research Study on the Manuscript
of Paris by Servetus (1546 description of the Pulmonary Circulation)
10
10
10
10.1
10.2
Images
11
raptor18, Chaldor, Maybelyn02, Blah28948, Luckas-bot, Joshyo, ZX81, Yobot, JohnnyCalifornia, II MusLiM HyBRiD II, Mmxx, THEN
WHO WAS PHONE?, Nallimbot, KamikazeBot, Ksyphon, SwisterTwister, Gunnar Hendrich, IW.HG, Tempodivalse, Synchronism, Slimbrowser, Backslash Forwardslash, AnomieBOT, DemocraticLuntz, Tryptosh, 1exec1, Jim1138, IRP, Dwayne, Piano non troppo, 90,
KRLS, Kingpin13, Materialscientist, Dromioofephesus, GB fan, ArthurBot, LilHelpa, Xqbot, Timir2, Nathspace, Brisbane99, JimVC3,
Capricorn42, Poetaris, Renaissancee, Acebulf, ArcadianOnUnsecuredLoc, Jmundo, Ched, The gr8 1, Inferno, Lord of Penguins, Drift6666,
Rangond, Abce2, Frosted14, Riotrocket8676, Frankie0607, Shirik, Doulos Christos, Egmslll, OT08, GainLine, Shadowjams, Vanished
user giiw8u4ikmfw823foinc2, Erik9, A.amitkumar, Fianlor, BoomerAB, Captain-n00dle, Prari, Nikhil8896, Tobby72, Van Brais, Samyahoogal, Lagelspeil, Baby gall, StaticVision, Michael93555, Recognizance, Andy corbett, HJ Mitchell, BusyBeth, Tegel, Iqinn, Jamesooders,
Kwiki, Lily pilly lost, HamburgerRadio, Citation bot 1, Dakchee, DrilBot, Pekayer11, Pinethicket, Wfjaxn, HRoestBot, Edderso, PvsKllKsVp, Rushbugled13, BRUTE, RedBot, SpaceFlight89, Williamfjackson, White Shadows, DC, FoxBot, HCUP US, Vrenator, MrX,
Amotlein, Allen4names, Reaper Eternal, Jhenderson777, Tbhotch, Reach Out to the Truth, Whateveryousaysir, SEMitchell, Minimac,
Imdabest88, Skirambler, DARTH SIDIOUS 2, Vladlen666, Carlos smith, Mean as custard, The Utahraptor, RjwilmsiBot, Landiskreeb,
Pilarian, ButOnMethItIs, Polarpanda, Agent Smith (The Matrix), DASHBot, CanadianPenguin, JDPurches, EmausBot, John of Reading, Orphan Wiki, WikitanvirBot, Immunize, Ajraddatz, Heracles31, Costas78~enwiki, GoingBatty, RA0808, Westonomor181, Westoonomor181, RenamedUser01302013, Sdfajklsdfajs, Mass234, Moswento, Tommy2010, Zonethree, Mickerz, Wikipelli, K6ka, Piraesam,
Mikijoe, Medicine2life, Buckhawk75, JSquish, Shisock, Maleris, Joelloyd7, Alpha Quadrant (alt), Sophisticated Fish!, Monterey Bay,
Wikiguys5, Makecat, OnePt618, Wagino 20100516, Thine Antique Pen, Demiurge1000, Brandmeister, Deed89, Donner60, Jcaraballo, Peter Karlsen, Wakebrdkid, Forever Dusk, TYelliot, DASHBotAV, Ellend-m, Woodyim9691, ResearchRave, Petrb, Helpsome, ClueBot NG,
Heysford, Gareth Grith-Jones, Jack Greenmaven, Bobandjerry, Cownangel, Cmc1868, Skullkid25, Satellizer, Hseynli Zeynalabdin Cavanir olu, Alexander Shatulin, Frietjes, Ethangeorge22, Marechal Ney, Uurkent, Widr, Oddbodz, Diyar se, Helpful Pixie Bot, Lowercase
sigmabot, BG19bot, TCN7JM, PhnomPencil, MusikAnimal, Amp71, Mark Arsten, Rm1271, Ace10000, Bobbyschneebly, Min.neel, Snow
Blizzard, Achowat, Mangal.anukriti, MrEctomy5422, BattyBot, Biosthmors, Fred C. Anderson, HueSatLum, Mdann52, Mrt3366, ChrisGualtieri, GoShow, Mediran, DeraDerron, Dustin Dewynne, Ssscienccce, MadGuy7023, Harsh 2580, BrightStarSky, Dexbot, Bjhodge8,
Webclient101, Mogism, Lugia2453, Samalways, CHU33 Z, Hmdpsych, Chaoseldarknight, DocElisa, JamesLacoeur, Epicgenius, Equilibrium Allure, BigBen36, Pritirokzz, Sausage525, Wikiwikixerupper, Iztwoz, Eyesnore, Tina usher, Touchtyper, PhantomTech, Tentinator,
Sideswipe917, Ugog Nizdast, LT910001, Earthbillion, BruceBlaus, Meteor sandwich yum, Onedirectionnumber1fan, Csutric, Filedelinkerbot, Calculus314, Rthom308, KH-1, PotatoNinja, Crystallizedcarbon, Eurodyne, EChastain, TaqPol, What are you doing doraemon,
Tilifa Ocaufa, Balllllllerrrrrrman0193, Kekekedkdk, Ksia,am, GymLAD7, Dennishfx, KasparBot, Fergus8181, David Mohammad Adam,
Nikolai petrov13, JeremiahY, Awesomejman3, Braxtonboss69, Mdunton16, Abhay vishal, Unenthusiastic and Anonymous: 2200
10.2
Images
File:2119_Pulmonary_Circuit.jpg Source: https://upload.wikimedia.org/wikipedia/commons/3/36/2119_Pulmonary_Circuit.jpg License: CC BY 3.0 Contributors: Anatomy & Physiology, Connexions Web site. http://cnx.org/content/col11496/1.6/, Jun 19, 2013. Original
artist: OpenStax College
File:Arteria-lusoria_MRA_MIP.gif Source: https://upload.wikimedia.org/wikipedia/commons/b/bd/Arteria-lusoria_MRA_MIP.gif
License: CC BY-SA 3.0 Contributors: Own work Original artist: Hellerho
File:Artery.png Source: https://upload.wikimedia.org/wikipedia/commons/d/d6/Artery.png License: CC0 Contributors: Own work Original artist: Lord of Konrad
File:Charta_ex_qva_figvram_parare_convenit,_illi_qvae_nervorvm_seriem_exprimit_appendendam,_1543..JPG
Source:
https://upload.wikimedia.org/wikipedia/commons/b/b1/Charta_ex_qva_figvram_parare_convenit%2C_illi_qvae_nervorvm_seriem_
exprimit_appendendam%2C_1543..JPG License: Public domain Contributors: Courtesy of the National Library of Medicine. Images
from the History of Medicine (IHM), http://ihm.nlm.nih.gov/images/A109086. Also showcased in the book: Hidden Treasure (New York,
NY: Blast Books, 2012), p. 18. Original artist: Vesalius, Andreas, 1514-1564. Andreae Vesalii Bruxellensis, scholae medicorum Patauinae
professoris, suorum de humani corporis fabrica librorum epitome. Call number: HMD Collection, WZ 240 V575dhZ 1543.
File:Commons-logo.svg Source: https://upload.wikimedia.org/wikipedia/en/4/4a/Commons-logo.svg License: ? Contributors: ? Original
artist: ?
File:Diagram_of_the_human_heart_(cropped).svg Source: https://upload.wikimedia.org/wikipedia/commons/e/e5/Diagram_of_the_
human_heart_%28cropped%29.svg License: CC-BY-SA-3.0 Contributors: Own work Original artist: ?
File:Erytrocyte_deoxy_to_oxy_v0.7.gif Source: https://upload.wikimedia.org/wikipedia/commons/7/75/Erytrocyte_deoxy_to_oxy_v0.
7.gif License: CC BY-SA 3.0 Contributors: Own work, partly based on File:Grafik blutkreislauf.jpg by Sansculotte. Original artist:
Rogeriopfm
File:Open_Circulatroy.gif Source: https://upload.wikimedia.org/wikipedia/commons/c/c3/Open_Circulatroy.gif License: CC BY-SA
4.0 Contributors: Own work Original artist: Mdunton16
File:Pseudoceros_bifurcus_-_Blue_Pseudoceros_Flatworm.jpg Source: https://upload.wikimedia.org/wikipedia/commons/5/50/
Pseudoceros_bifurcus_-_Blue_Pseudoceros_Flatworm.jpg License: CC BY 2.0 Contributors: http://www.flickr.com/photos/steve_childs/
233603352/ Original artist: Stephen Childs
File:Two_chamber_heart.svg Source: https://upload.wikimedia.org/wikipedia/commons/c/c2/Two_chamber_heart.svg License: CC BY
3.0 Contributors: Own work Original artist: Ahnode
File:Vein_art_near.png Source: https://upload.wikimedia.org/wikipedia/commons/1/1d/Vein_art_near.png License: CC BY-SA 2.1 jp
Contributors: Anatomography Original artist: BodyParts3D/Anatomography
File:Wiki_letter_w_cropped.svg Source: https://upload.wikimedia.org/wikipedia/commons/1/1c/Wiki_letter_w_cropped.svg License:
CC-BY-SA-3.0 Contributors:
Wiki_letter_w.svg Original artist: Wiki_letter_w.svg: Jarkko Piiroinen
File:Wikibooks-logo.svg Source: https://upload.wikimedia.org/wikipedia/commons/f/fa/Wikibooks-logo.svg License: CC BY-SA 3.0
Contributors: Own work Original artist: User:Bastique, User:Ramac et al.
12
10
10.3
Content license