Code.

No: 36080
R05 SET-1
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
III B.TECH II SEM SUPPLEMENTARY EXAMINATIONS FEBRUARY - 2010
IMMUNOLOGY
(BIO-TECHNOLOGY)
Time: 3hours Max.Marks:80
Answer any FIVE questions
All questions carry equal marks
---

1.a) Write note on structural elucidation of antibody

b) Write detailed notes on innate immunity [8+8]

2.a) Write notes on development of T-lymphocytes.

b) Explain natural killer cells. [8+8]

3.a) Explain about spleen with neat labeled diagram.

b) Write notes on lymph nodes. [8+8]

4.a) Write notes on function and classification of immunoglobulin.

b) Explain the genetic control of antibody production. [8+8]

5. Write detailed notes on production and applications of monoclonal antibodies. [16]

6. a) Classify T-cells.
b) How antigen can be processed and presented to T cell? [8+8]

7. a) Write notes on hypersensitivity.

b) Explain principle of antigen antibody reactions. [8+8]

8. a) Explain auto immunity.

b) Write notes on graft rejection. [8+8]

--ooOoo--

1
 Code.No: 36080
R05 SET-2
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
III B.TECH II SEM SUPPLEMENTARY EXAMINATIONS FEBRUARY - 2010
IMMUNOLOGY
(BIO-TECHNOLOGY)
Time: 3hours Max.Marks:80
Answer any FIVE questions
All questions carry equal marks
---

1.a) Write notes on cell mediated immunity.

b) What are the factors that influence immunogenicity? [8+8]

2.a) What are the different cells that participate in immune response?
b) Write notes on development of B-lymphocyte. [8+8]

3. Explain in detail about

a) thymus
b) spleen. [16]

4.a) Explain the genetic control of antibody production.

b) Write notes on isotype, allotype, idiotype. [8+8]

5.a) Write the production of monoclonal antibodies.

b) Write notes on activation and differentiation of B-cell. [8+8]

6.a) Give a note on mutated T cells.

b) How antigen can be processed and presented to T cell? [8+8]

7. Write notes on the following:

a) ELISA
b) Agglutination [8+8]

8.a) What is the evidence of graft rejection?

b) Write notes on immunosuppressive drugs. [8+8]

--ooOoo--

2
 Code.No: 36080
R05 SET-3
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
III B.TECH II SEM SUPPLEMENTARY EXAMINATIONS FEBRUARY - 2010
IMMUNOLOGY
(BIO-TECHNOLOGY)
Time: 3hours Max.Marks:80
Answer any FIVE questions
All questions carry equal marks
---

1.a) Explain the structure of antibody.

b) Explain Phagocytes and inflammation. [8+8]

2.a) Write notes on dendrite cells and macrophages as immune cells.

b) Explain killing of cancer cell by natural killer cell. [8+8]

3.a) Write notes on any one of primary lymph organ.

b) Explain Lymph node. [8+8]

4.a) Write notes on function and classification of immunoglobulin.

b) Explain the genetic control of antibody production. [8+8]

5. Write detailed notes on hybridoma technology. [16]

6.a) Write notes on cell mediated immunity.

b) Explain T cell activation. [8+8]

7.a) Explain the principle of antigen antibody interactions.

b) Write notes on Radio immune assay. [8+8]

8. a) Give note on tumor therapy.

b) Explain the mechanism of graft rejection. [8+8]

--ooOoo--

3
 Code.No: 36080
R05 SET-4
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
III B.TECH II SEM SUPPLEMENTARY EXAMINATIONS FEBRUARY - 2010
IMMUNOLOGY
(BIO-TECHNOLOGY)
Time: 3hours Max.Marks:80
Answer any FIVE questions
All questions carry equal marks
---

1.a) Explain in detail the types of immunities with examples.

b) Write notes on haptane and role of adjutants in immunogenicity. [8+8]

2.a) Write notes on development of T-lymphocytes

b) Give a brief notes on Haematopoiesis. [8+8]

3.a) Write notes on any one of secondary lymph organite.

b) Write notes on spleen. [8+8]

4.a) Explain the genetic control of antibody production.

b) Write notes on immunoglobulin super family. [8+8]

5.a) Write the applications of monoclonal antibodies.

b) Explain differentiation of B-cell. [8+8]

6.a) Write notes on antigen processing and presentation by T cell.

b) Give the classification of T cells. [8+8]

7. Explain the following:

a) Precipitation
b) ELISA [8+8]

8.a) What are immunosuppressive agents? Write their applications.

b) Write notes on mechanism of graft rejection. [8+8]

--ooOoo--