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TEST AP101-3
Questions:
Test Duration:
225 minutes
Reading Time:
20 minutes
INSTRUCTION:
Only Bilingual Dictionaries allowed, NO NOTES. This test consists of one part, 185 multiple choice questions
(numbers 1 to 185) to be answered on the computer answer sheet (185 marks). Write your name and student
number in the spaces provided on the computer answer sheet. Carefully fill in the shapes on the computermarked answer sheet under your name and ID number with a 2B pencil. You must only use a 2B pencil on the
computer answer sheet. Please read the instructions on the answer sheet carefully and follow them precisely.
Select the best answer to questions. If you are unsure of an answer, eliminate the alternatives that you know
to be incorrect and select answer from the remaining alternatives. To indicate your selection, use a 2B pencil
to blacken the corresponding oval on the computer answer sheet, AP101-1. No marks are deducted for wrong
answers. So students are advised to move on quickly without wasting too much time on one question. Advanced questions; require further reading or online research.
Digestion
1. In addition to storage and mechanical breakdown of food, the stomach:
A. is the first site where chemical digestion of starch takes place
B. is the only place where fats are completely digested
C. is the first site where absorption takes place
D. initiates protein digestion and denatures proteins
2. The chemical and mechanical processes of food breakdown are called:
A. absorption
B. digestion
C. secretion
D. ingestion
3. Parietal cells of the stomach produce:
A. mucin
B. pepsinogen
C. hydrochloric acid
D. rennin
4. Which of the following is not true of oblique layer in the stomach ()?
A. allows pummel the food and hence physical breakdown of bolus
B. allows ram the food into the small intestine
C. is a layer of muscularis externa
D. folds into oblique folds called rugae which increases the surface area
5. The solutes contained in saliva include:
A. only proteases and amylase
B. mucin, lysozyme, electrolytes, salts, and minerals
C. only salts and minerals
D. electrolytes, digestive enzyme, mucin, lysozyme, wastes, and IgA
6. The function of the hepatic portal circulation is to:
A. collect absorbed nutrients for metabolic processing
B. return glucose to the general circulation when blood sugar is low
C. distribute hormones
D. carry toxins to the venous system for disposal through the urinary tract
7. When we ingest large molecules such as lipids, carbohydrates, and proteins, they must undergo catabolic
reactions whereby enzymes split these molecules. This series of reactions is called:
A. absorption
B. secretion
C. chemical digestion
D. mechanical digestion
22. Absorption is one of digestive processes. Venous blood containing absorbed nutrients enters:
A. Peyers patches
B. pancreas
C. liver
D. gallbladder
23. The ingestion of a meal high in fat content would cause which of the following to occur?
A. severe indigestion would occur, caused by the lack of sufficient digestive enzymes
B. bile would be released from the gallbladder to emulsify the fat in the duodenum
C. the acid secretions from the stomach would be sufficient to digest this food
D. this type of food would cause secretion of gastrin to cease, causing digestive upset
24. Which vitamin requires intrinsic factor in order to be absorbed?
A. C
B. K
C. B12
D. A
25. The chemical and mechanical processes of food breakdown are called:
A. digestion
B. absorption
C. secretion
D. ingestion
26. Chief cells of the stomach ():
A. produce mucin
B. produce pepsinogen
C. produce amylase
D. produce HCl
27. The pancreas:
A. secretes pancreatic juice through a duct into the stomach
B. secretes lipase, nuclease, and amylase
C. is an immune organ that humans can easily live without
D. secretes bile
28. A person who lacks the hormone ghrelin would be expected to:
A. regulate the digestion of lipids
B. feel less or less frequently hungry, and may lose weight
C. have a lack the production of insulin
D. not feel full after a meal
29. The liver:
A. sends blood into the hepatic portal vein
B. produces amylase and regulates metabolism of sugars and fats
C. produces bile and regulates metabolism of sugars and fats
D. is retroperitoneal
5
36. Which of the following is true of phases of regulation of gastric secretions ()?
A. cephalic phase is stimulated by the sight or smell of food
B. intestinal phase is stimulated by partially digested proteins and fats
C. gastric phase is stimulated by distension of the stomach and low acidity
D. A, B and C are correct
37. Which of the following incorrectly matches a structure of the small intestines with its description?
A. ileum contains the valve that connects to the liver
B. microvilli are also known as the brush border
C. villi are fingerlike projections of the mucosa
D. duodenum contains openings for the bile and pancreatic ducts
38. The hepatopancreatic ampulla is formed from the union of the:
A. cystic duct and interlobular duct
B. greater duodenal papilla and the lesser duodenal papilla
C. pancreatic duct with the lacteals
D. bile duct and main pancreatic duct
39. In order to prevent self-digestion of the pancreas, activation of pancreatic proteases occurs in the:
A. duodenum
B. pancreas
C. stomach
D. liver
40. During deglutition (swallowing), the bolus passes into the stomach from the oesophagus through the:
A. urethral sphincter
B. oesophageal sphincter
C. gastroesophageal sphincter
D. pyloric sphincter
41. During the intestinal phase of gastric regulation ():
A. secretin causes more HCl release
B. the stomach is initially stimulated and later inhibited
C. the gastroenteric reflex reduces stomach activity
D. hormones reduce chief cell activity
42. What is the main organic molecule digested in the stomach?
A. proteins
B. nucleic acids
C. carbohydrates
D. lipids
43. The propulsive function that occurs in the oesophagus is called:
A. swallowing
B. defecation
C. peristalsis
D. segmentation
44. Which of the following is a characteristic of the large intestine?
A. it is the site for acid neutralization
B. it contains a large number of bacteria
C. is longer than the small intestine
D. it provides no absorptive function
7
45. From the esophagus to the anal canal, the walls of every organ of the alimentary canal are made up of the
same four basic layers. Arrange them in order from the lumen ().
A. mucosa, submucosa, muscularis, and serosa
B. serosa, mucosa, submucosa, and muscularis
C. muscularis, serosa, mucosa, and submucosa
D. submucosa, serosa, muscularis, and mucosa
46. Which regulatory chemical stimulates gastric gland activity and motility?
A. vasoactive peptide
B. secretin
C. gastrin
D. CCK
47. Which sequence below represents the correct layering of the wall of the GI tract, starting from the layer
next to the lumen ()?
A. muscularis externa, serosa, submucosa, mucosa
B. mucosa, muscularis externa, submucosa, serosa
C. mucosa, submucosa, muscularis externa, serosa
D. serosa, mucosa, muscularis externa, submucosa
48. Which of the following incorrectly matches a substance involved in organic molecule digestion with its
description ()?
A. sucrase, lactase, and maltase; pancreatic enzymes that act on disaccharides
B. bile; emulsifies fats for digestion
C. trypsin; digests proteins in the small intestines
D. none of the above (all correct)
49. What would be the effect of stripping the small intestines of their villi?
A. greater absorption of nutrients would occur
B. decreased surface area for absorption, which in turn would cause malnutrition & weight loss to occur
C. the large intestine would take over as the primary absorptive site
D. a duodenal ulcer
50. Which of the following products does the stomach produce?
A. pepsinogen and secretin
B. bile and trypsin
C. HCl and intrinsic factor
D. mucous and amylase
51. Which of the following is not a function of liver?
A. excretes bilirubin
B. activation of vitamin D
C. has a role in deoxification
D. stores water-soluble vitamins and minerals
the
.
A. slow, slow, slow, absorption of nutrients, small intestine
B. speed up, speed up, speed up, digestion of nutrients, small intestine
C. slow, slow, slow, digestion of indigestible food, large intestine
D. speed up, speed up, speed up, absorption of water, large intestine
exit
the
in
10
11
12
80. Digestion of carbohydrates and proteins by brush border enzymes occurs within the ________ of the
small intestine.
A. rugae
B. microvilli
C. villi
D. goblet cells
81. Bile is stored and concentrated in the:
A. liver
B. pancreas
C. gallbladder
D. stomach
82. Emesis is a process which involves contraction of ():
A. diaphragm
B. esophageal hiatus
C. both diaphragm and abdominal muscles
D. all of the above
83. Which of the following is not a characteristic of the liver?
A. has a role in detoxifying the blood
B. highly regenerative
C. stores glucose in form of glycogen
D. none of the above
84. _______ is not found in pancreatic secretions.
A. chymotrypsinogen
B. bicarbonate
C. cholecystokinin (CCK)
D. procarboxypeptidase
85. Most water is absorbed in the:
A. liver
B. stomach
C. large intestine
D. small intestine
86. Gastric juice is:
A. pancreatic secretions
B. stomach secretions
C. hepatic secretions
D. all of the above
13
87. Biliary calculi are solidified cholesterol and bile salts which causes vague discomfort, jaundice, and pain in
the upper abdomen. This is formed at:
A. gallbladder
B. liver
C. pancreas
D. duodenum
88. Bacterial flora in the large intestine do not produce:
A. B vitamins
B. vitamin K
C. carbon dioxide
D. intrinsic factor
89. Which of the following incorrectly matches a nutrient and its monomer?
A. nucleic acids; DNA and RNA
B. lipids; fatty acids and monoglycerides
C. proteins; amino acids
D. carbohydrates; monosaccharides
90. Pepsin enzymatically digests:
A. carbohydrate
B. nucleic acids
C. protein
D. fat
91. In buccal cavity, there are partial degradation or chemical breakdown of:
A. carbohydrate
B. lipid
C. protein
D. both A and B
92. Which of the following increases intensity of segmentation?
A. sympathetic division of ANS
B. somatic nervous system
C. parasympathetic division of ANS
D. cooperative behaviours of both sympathetic and parasympathetic division of ANS
93. Which of the following is not a true statement?
A. the primary goal of digestive tract regulatory mechanisms is to optimize nutrient breakdown and
absorption
B. a weak gastroesophageal sphincter can result in heartburn
C. most digestion occurs in the small intestine
D. constipation results when food passes too quickly through the small intestine
14
and this
96. Which of the following tunics of digestive tract secretes fluid that lubricates the mobile digestive organs?
A. serosa
B. muscularis externa
C. submucosa
D. mucosa
97. Which of the following does not occur during vomiting?
A. profuse salivation
B. sweating
C. a decrease in heart rate
D. nausea
98. Which of the following is/are extrinsic autonomic nerves involved in regulating digestive processes?
A. sympathetic and parasympathetic
B. parasympathetic only
C. sympathetic only
D. enteric nervous plexus
99. When mucosa of alimentary canal is penetrated, there is a relatively high risk of microbial infections
because all surfaces of GITs are exposed to the external environment. In oral cavity, which of the
following is produced in response to a tissue (mucosa) injury?
A. IgA
B. lymphocytes
C. defensins
D. saliva
100.
A.
B.
C.
D.
In which of the following chemical digestion does not involve brush border enzymes?
protein digestion
lipid digestion
carbohydrate digestion
none of the above
101. The thick stratified squamous epithelium of the oral cavity provides protection against abrasion. This
epithelisum is:
15
A.
B.
C.
D.
102.
A.
B.
C.
D.
keratinised
melanised
composed of a large number of mast cells
covered with a sticky layer of defensin
Which of the following is responsible for saliva secretion?
parotid gland
sublingual gland
submandibular gland
all of the above
103. Throughout the digestive tract, food can be compacted and partially digested. Which of the following
correctly matches name of food mass along a digestive passage and a location of its formation (start from
food)?
A. chyme (esophagus), bolus (stomach), faeces (large intestine)
B. bolus (mouth), chyme (esophagus), faeces (small intestine)
C. chyme (esophagus), bolus (small intestine), faeces (rectum)
D. bolus (mouth), chyme (stomach), faeces (large intestine)
104.
A.
B.
C.
D.
105.
A.
B.
C.
D.
Although stomach is corrosively acidic, it is not normally damaged by its acidity because it produces:
pepsinogen
intrinsic factor
mucosal barrier
serotonin
106.
A.
B.
C.
D.
Excessive emesis can have negative effects on health. Which of the following is not one of them?
damaged mucosa of buccal cavity
dehydration
metabolic acidosis
disturbances in electrolyte balances
107.
A.
B.
C.
D.
16
108.
A.
B.
C.
D.
109. Although we can swallow voluntarily, it is impossible to consciously control swallowing when bolus
has reached:
A. gastroesophageal sphincter
B. nasopharynx
C. oropharynx
D. oral orifice
110. A soft, retroperitoneal gland which produces a variety enzymes that break down all categories of
foodstuffs, is
and it delivers enzymes to
for chemical digestion.
A. liver, hepatopancreatic ampulla
B. pancreas, duodenum
C. liver, jejunum
D. pancreas, pancreatic duct
112.
A.
B.
C.
D.
113.
A.
B.
C.
D.
114.
A.
B.
C.
D.
Chemical digestion reduces large complex molecules to simpler compounds by the process of:
fermentation
anabolism
mastication
catabolism
17
115.
A.
B.
C.
D.
The process of breaking triglycerides down into glycerol and fatty acids is known as:
gluconeogenesis
lypogenesis
lipolysis
fat utilization
116.
A.
B.
C.
D.
The molecule that serves as the major source of readily available body fuel is:
glucose
fat
acetyl CoA
cellulose
117.
A.
B.
C.
D.
118.
A.
B.
C.
D.
119.
A.
B.
C.
D.
120.
A.
B.
C.
D.
121.
A.
B.
C.
D.
Which of the following incorrectly matches an events of metabolism with the process occurring.
gluconeogenesis; production of glucose from a noncarbohydrate source
lipogenesis; triglyceride synthesis
glycogenesis; polymerization of glucose
transamination; NH3 synthesis
122.
A.
B.
C.
D.
The process of breaking triglycerides down into glycerol and fatty acids is known as:
lipolysis
fat utilization
gluconeogenesis
lypogenesis
18
123.
A.
B.
C.
D.
124.
A.
B.
C.
D.
125.
A.
B.
C.
D.
Which of the following is the amount of energy the body needs to maintain life?
BMI
MR
TMR
BMR
126.
A.
B.
C.
D.
127. ______ is considered "good" cholesterol; high blood levels of this cholesterol are thought to be
beneficial. For example, it prevents atherosclerosis and reduces the risk of heart attack.
A. HDLs (high density lipoproteins)
B. LDLs (low density lipoproteins)
C. chylomicrons
D. VLDLs (very low density lipoproteins)
128. Cholesterol, while it is not an energy molecule, has importance in the body because:
A. it helps provide essential nutrients to the brain and lungs
B. it is a stabilizing component of the plasma membranes and is the parent molecule of steroid
hormones
C. it helps mobilize fats during periods of starvation
D. it enters the glycolytic pathway without being altered
129.
A.
B.
C.
D.
19
130.
A.
B.
C.
D.
131.
A.
B.
C.
D.
132.
A.
B.
C.
D.
136.
A.
B.
C.
D.
Among the conditions required for measuring the basal metabolic rate is:
being in an absorptive state
keeping the room temperature between 20 and 25 degrees C
remaining in an upright position
sleeping
20
137.
A.
B.
C.
D.
138.
A.
B.
C.
D.
The hormone responsible for setting the basal metabolic rate is:
insulin
thyroxine
melatonin
glucagon
139.
A.
B.
C.
D.
140.
A.
B.
C.
D.
141.
A.
B.
C.
D.
The amount of ________ produced is probably the most important factor in determining BMR.
prolactin
thyroxine
norepinephrine
ADH
142.
A.
B.
C.
D.
143.
A.
B.
C.
D.
144.
A.
B.
C.
D.
145.
A.
B.
C.
D.
For a healthy normal individuals, proteins are essential to the body for all of the following except:
formation of functional molecules like hemoglobin and cytochromes
production of enzymes, clotting factors, and antibodies
production of energy
production of some hormones
146.
A.
B.
C.
D.
147.
A.
B.
C.
D.
148. Which of the following incorrectly match a vitamin with its function?
A. Vitamin A; required for synthesis of photoreceptor pigments in vision; integrity of skin, mucosae, and
normal bone; and tooth development
B. Vitamin K; enhances absorption of calcium; works in conjunction with hormones regulating calcium
blood levels
C. Vitamin D; essential for formation of clotting proteins; intermediate in electron transport; participates
in oxidative phosphorylation
D. both B and C
149. In the case of a person who consumes a normal, balanced diet, proteins are essential to the body for
all of the following except:
A. production of energy
B. production of some hormones
C. production of enzymes, clotting factors, and antibodies
D. formation of functional molecules like hemoglobin and cytochromes
150.
A.
B.
C.
D.
151.
A.
B.
C.
D.
152.
A.
B.
C.
D.
153.
A.
B.
C.
D.
154.
A.
B.
C.
D.
155. Small intestine receives substances from liver and pancreas for chemical digestion. Which of the
following is not one of these?
A. Vitamin B12
B. bile
C. digestive enzymes except brush border enzymes
D. bicarbonate ions
156. Amino acid rich sources such as ______ are important as they are a primary source of ______, which
is required for_______.
A. meat, glucose, fat production
B. fish, protein, enzyme production
C. pasta, glucose, ATP production
D. cheese, fat, ATP production
157. Which of the following is a micronutrient (that is, a nutrient required in minute amounts), not a major
nutrient?
A. water
B. lipids
C. minerals
D. proteins
158.
A.
B.
C.
D.
Insulin:
is abundant in the blood in the starved state
stimulates glycolysis in liver and muscle
stimulates glycogenesis in liver and muscle tissues
is used to produce ATP in cells
23
159.
A.
B.
C.
D.
160.
A.
B.
C.
D.
Which of the choices below is not a fate of carbohydrate taken into the body?
ATP production
lipogenesis
conversion to a nucleic acid
glycogenesis
161.
A.
B.
C.
D.
The molecule that serves as the major source of readily available body fuel in the fed state is:
fat
acetyl CoA
glucose
cellulose
162.
A.
B.
C.
D.
163.
A.
B.
C.
D.
164.
A.
B.
C.
D.
165.
A.
B.
C.
D.
166.
A.
B.
C.
D.
167.
A.
B.
C.
D.
168. When ketone bodies are present in the blood and urine in large amounts, it usually indicates
increased metabolism of:
A. proteins
B. fats
C. glucose
D. lactic acid
169.
A.
B.
C.
D.
What is the preferred use order of energy sources for the body?
glycogen, blood glucose, protein, fat
blood glucose, glucagon, fat, protein
blood glucose, glycogen, fat, protein
the body has no preference for which energy sources to use
170.
A.
B.
C.
D.
Most vitamins:
have only one function in the body
function as coenzymes in the body
are metabolized to make ATP
are used as building blocks for the body
171.
A.
B.
C.
D.
172.
A.
B.
C.
D.
173.
A.
B.
C.
D.
The hormone that controls essentially all events of the absorptive state is:
thyroxine
ADH
insulin
glucagon
25
174. The role of _____________ is to transport excessive cholesterol from peripheral tissue to the liver,
where it is broken down and becomes part of bile.
A. high-density lipoproteins (HDLs)
B. very-low-density lipoproteins (VLDLs)
C. low-density lipoproteins (LDLs)
D. Chylomicrons
175.
A.
B.
C.
D.
176. ___________ acts to suppress appetite by inhibiting _____, which is the most-powerful known
appetite stimulant.
A. leptin; neuropeptide Y
B. growth hormone; lipase
C. insulin; glucagon
D. serotonin; adrenaline
177.
A.
B.
C.
D.
178.
A.
B.
C.
D.
179.
A.
B.
C.
D.
The ability to convert one type of molecule to another is truly remarkable in the body, specially:
pancreas
skeletal muscle
adipose tissue
liver
180.
A.
B.
C.
D.
26
181.
A.
B.
C.
D.
182.
A.
B.
C.
D.
Which of the following organ does not prefer fatty acids as an energy fuel?
liver
cardiac muscle
resting skeletal muscles
brain
. In the post-
184.
A.
B.
C.
D.
Ingested
are absorbed via lymph.
monosaccharides
amino acids
fats
nucleic acids
185.
A.
B.
C.
D.
27