DRUGS ACTION INDICATIONS ADVERSE NURSING

EFFECTS/SIDE CONSIDERATIONS
EFFECTS AND
RESPONDSIBILITIES
Generic Name: Adverse Reactions:
Isoniazid INH >Peripheral neuritis, >Special precautions on
> All forms of TB optic neuritis; psychotic patients with renal or
Brand Name: reactions, convulsions , hepatic impairment;
Nydrazid epigastric distress,
convulsive disorders;
visual disturbances,
Drug Classification: fever, rash, pyridoxine history of psychosis;
Antituberculous agent deficiency, micturition
>patients at risk of
difficulty
Dosage: neuropathy or
pyridoxine deficiency
Potentially e.g., diabetic, alcoholic,
Frequency: Fatal: Hepatotoxicity malnourished, uremic,
infected with HIV.

Side Effects: >Careful monitoring of

> May cause stomach hepatic function
upset, heartburn,
nausea or dizziness >Check hepatic
function before and
during treatment.

>Special precautions on
patients with liver or
kidney impairment,
patients taking other
hepatotoxic agents.
Convulsive disorders,
diabetes mellitus,
chronic alcoholism

Generic Name: Adverse Reactions:

Pyrazinamide >Failure after adequate Hepatotoxicity >Special considerations
treatment w/ primary (hepatomegaly, on patients with
Brand Name: drugs (INH, splenomegaly and Diabetes, renal failure,
jaundice may develop
 streptomycin, PAS) in and in rare case history of gout.
Drug Classification: any form of active TB. fulminating acute
Antituberculous agent yellow atrophy and >Monitor liver function
death). arthralgia, and serum uric acid
Dosage: malaise, regularly
hyperuricaemia,
abnormal LFT, skin >Liver function tests
Frequency: rashes. should be carried out
Potentially
prior to & every 2-4 wk
Fatal: Severe liver
damage, fulminant during therapy.
hepatitis Diabetes mellitus.

Side Effects:
>Fever, porphyria and d
ysuria
> Gl disturbances
including nausea,
vomiting and anorexia
Generic Name: Adverse Reactions:
Ethambutol >treatment of
pulmonary and extra >Retro bulbar neuritis >Impaired pre-
Brand Name: pulmonary TB with a reduction in treatment visual acuity
Myambutol visual acuity, in elderly.
constriction of visual
Drug Classification: field, central or >Perform liver, kidney
Antituberculous agent peripheral scotoma and
and visual acuity tests
green-red color
Dosage: blindness. Retinal regularly.
hemorrhage (rare);
>Caution when
reduced renal clearance
Frequency: of urates (acute gout); assessing visual acuity
confusion, in patients with
hallucinations, malaise, cataracts, DM, recurrent
jaundice; eye inflammation to
thrombocytopenia; make sure that changes
pulmonary infiltrates
are not due to the
underlying causes
Side Effects:
 > May cause stomach
upset, dizziness,
fatigue, or headache.
Generic Name: Adverse Reactions:
Acetylcysteine > Acute & chronic > Flushing, fever,
respiratory tract stomatitis, rhinorrhoea, > Special
Brand Name: affections w/ abundant bronchospasm, considerations on
anaphylactoid Asthmatic patients,
mucous secretions
reactions, rashes.
history of
Drug Classification: >cough and cold Rarely, blurred vision,
bradycardia, syncope, bronchospasm, peptic
preparations
thrombocytopenia, ulceration.
Dosage: convulsions.
Potentially > GI upsets, stomatitis,
Fatal: Rarely, rhinorrhea, headache,
Frequency: respiratory or cardiac tinnitus, urticaria, chills,
arrest. fever, hemoptysis.
Rarely, anaphylactic
reactions
Side Effects:
> may cause nausea,
vomiting, drowsiness,
runny nose,
clamminess, fever and
an unpleasant odor the
first several days as
your body adjusts to the
medication
Generic Name: Adverse Reactions:
Moriamin forte >malnutrition, protein >hypervitaminosis
and vitamin
Brand Name: deficiencies, anemia,
Side Effects:
convalescence,
>constipation, but also
Drug Classification: restoration and
cramping, nausea, and
Multivitamins with maintenance of body
vomiting
minerals resistance adjuvant in
the therapy of peptic
Dosage: ulcer and TB

Frequency: