Pharmacology

35 MCQ

& Pharmaceutics
Biopharmaceutics

15 MCQ

Pharmacy calculation

5 MCQ

Pharmacy Practices & Clinical

Pharmacy

15 MCQ

Total

70

-1
-2
-3
-4

70 MCQ




30

Almost All questions were twisted; questions and multiple

& answers were changed, so fully prepare 400, 300,120,

also 800 kits. And Classifications from Lippincott 5 th Edition

are must, without classification u can be in trouble so be
careful
All you need to clarify the concept about all dugs never use rattafication method
because most of the questions are twisted.
This questions come to me and other pharmacist in the same day in Dubai and I
take time on written Question and arranged and select true choice.
Good luck my friends and please ask God for help me in my life
Thanks for all
The action of histamine is :
a-capillary constriction
pressure
c-stimulation of gastric secretion
d-skeletal muscle paralysis

b-elevation of blood
e-slowing the heart rate

One of the following antibiotics is resistant to penicillinase :

a-penicillin V
b-penicillin G
c-floxapen
d-ampicillin
e-amoxicillin
Inderal is :
a-similar in action to ergotamine
b-similar in action to tubocurarine
c-used as an antihistamine
d-pure b -adrenergic receptor blocker
Which of the following is non selective b1 blocker ?
a-labitolol
b-terazosine
c-cloridine
d-captopril
e-verapamil
Erythroped A :
a-is effective against G +ve Cocci
b-is a macrolide antibiotic
c-can increase g.i.t. motility
d-could be used in pregnant women if need
e-all of the above
For the treatment of anaphylactic shock use :
a-salbutamol
c-acetazolamide
e-aminophylline

b-diphenhydramine
d-epinephrine

49

The mechanism of action of atropine is :

a-muscarinic antagonist
b-muscarinic agonist
c-nicotinic antagonist
d-nicotinic agonist
e-non of the above
Myocardial muscle tissue property to generate electrical is :
a-inotropy
b-chronotropy
c-automaticity
d-contractility
e-non of the above " Dromotropic effect"
Adenosine is used for :
a-ventricular arrythmias
b-atrial bradycardia
c-supraventricular tachycardia
d-supraventricular bradycardia
e-non of the above
Which of the following is responcible for buffering
a-magnesium
b-chloride
c-bicarbonates
d-potassium
e-troponin
The term shock signifies :
a-hyperperfusion
tachycardia
d-bradycardia

b-hypoperfusion

c-

e-non of the above

the amount of water in adult male is about:

a-25%
b-60%
c-80%
e-17%

d-10%

Which of the following are causes of oedema?

a- Increase hydrostatic pressure
b- Decrease oncotic pressure
c-capillary permeability
d- a and b

e- a , b and

Patients prescribed non reversible monoamine oxidase inhibitor

should be advised not to consume food containing tyramine
because this combination causes:
a-postural hypotension
b-hallucinations
c-anaphylactic shock
d-muscle weakness and
tremor
e-acute adrenergic crisis including sever
hypertention
Concerning COX 2 inhibitors , which is NOT true?
a-they have lower risk gastric adverse reactions
b-good evidence about their effectiveness

c-cardiac toxicity is a recent concern of this class

d-they usually administrated twice daily
e-combination with non selective agents give more effective
action
In the treatment of osteoporosis which of the following is NOT
true?
a-alendronate should be taken 60 min. before breakfast
b-Ca and vit. D are essential
c-hormone replacement therapy should be considered
d-outcome should be assessed with periodic bone density
e-raloxifeno is selective oestrogen modulator
Which of the following is the first choice in acute gout?
a-allopurinol
b-indomethacin
c-colchicine
d-probencid
sulfinylpyrazone

e-

Early symptoms of aspirin poisoning are :

a-lethergy & fatigue b-skin rash & headache
c-throbbing headache & dizziness
d-fluid retention hypotension
e-ringing in the ears & blurred vision
A disease modifying drugs in rheumatoid arthritis:
a-gold preparations
b-hydroxychloroquine
c-methotrexate
d- a and b
e- a , b and c
Which of the following drugs
exhibits dose dependant pharmaceutical therapeutic doses ?
a-Na valproate
b-phenytoin
c-lithium
d-quinidine
e-carbamazepine

Propranolol is often prescribed with hydralazine to

a-reduce the reflex tachycardia
b-prevent the accumulation of hydralazine.
c-prevent systemic lupus ( SLE ) due to hydralazine.
d-prevent oedema
e-increase absorption of
hydralazine
The drug of choice to control pain during acute myocardial
infarction is :

a-naloxone
morphine

b-bethidine

d-celecoxib

e-naproxen

c-

What is a major contraindication to the use of an OTC

sympathomimetic drug
a-gastric ulcer

b-uncontrolled hypotension

c-severe asthma

d-rheumatoid arthritis

e-hypertension
When concidering drug therapy for hypertention , which is true?
a-combination of drugs always preferred
b-hydralazine is first line therapy in young hypertension
c-furosemide should be administrated before meal to improve
absorption
d-beta-blokers should be avoided in asthmatic patient
e- ACEIs are recommended in pregnant women
Which of the following is NOT used in theophylline toxicity
management :
a-symptomatic control of seizures with benzodiazepine
b-activated charcoal to enhance elimination
c- b blocker for tachycardia
d-control vomiting with metoclopramide
e-methylphenidate to reduce excessive sedation
The antimalarial to be avoided in glucose-6-phosphate
dehydrogenase deficiency :
a-primaquine
c-chloroguanide

b-quinine

The following is NOT characteristic of solution:

a-thermodynamically stable
b-composed of two or more component that exist in one phase
c-homogenous

d-the solvent and solute can be separated by filtration

e-solute doesn`t precipitate as time passes
which of the following need filtration before IV infusion
a- mannitol
c- insulin

b- dextrose 5%

d- Suspension

e- emulsion

to increase duration of lidocaine in anasethia

a- propranolol

b- succinyl choline

c- epinephrine

d- Atropine
which of the following are characteristic for Erythrosine:
a-not effective against G+ve cocci
b- has amino glycoside antibiotic
c-decrease GIT motility
d-should not be used in pregnant woman if need
e-should be used in pregnant woman if need
which of the following has aldosterone antagonist effect
a- amiloride
c- spironolactone

b- furosemide
d- hydrochlorothiazide

Chiral molecule mean:a-dipole moment

c- chelating prep.

b- solubility
d-optical activity.

lovastatin produce action through:HMG-co reductase inhibitor.

qqh is abbreviation for every four hour.
tegretol is used in ttt of:status epileptic, seizures.
Bambuterol is used in:treatment of asthma.
Drug used in ttt of traveler diarrhea:a-ampicillin
c- co-trimoxazole

b- amoxicillin
d- ciprofloxacin

solid to be reduced in size before dissolving called:disintegration.

Benzodiazepine mechanism through:bindinsubunit of GABA-A receptor.

most common process for sterilization:a- filtration
c- moist heat

b- dry heat

which of the following need serum level monitoring

with Quinidine:a-Digoxin
c-ampicillin
and HTN:-

b- albutrol
116-drug used for ttt of migraine

a-clonidine
c- propranolol

b- minoxidil
d- hydralazin

normal water can be used in:a- parentral prep.

c- oral susp.

b-ophthalmic prep.
d-external prep.

Ecothiophate mechanism through:a-binding to muscarinic receptor

antagonist

b- cholinergic

c- make complex with acetylcholinesterase and inhibit its action

if a drug has the same active ingredient like other drug but not
contain the same inactive ingredient this mean :a- Bioequivalent
c- pharmaceutical alternative

b-pharmaceutical equivalent
d- A,B

sildenafil is found in Viagra.

which of the following not used in ttt of asthma:a- B2 agonist

b-B2 antagonist

primidone is prodrug fo146- Daily recommended dose for vit. C in

male :a-30mg/day
90mg/day
mg/day

b-50 mg/day
d-200 mg/day

Digoxin toxicity increase with:a- renal failure

b- hepatic pt

ce- 400

c- Asthmatic pt
All the following are side effect of oral contraceptive except:a-hypertension

b-weight gain

c- Hyperglycemia

d- dizziness

e- constipation

phenytoin act on voltage gated Na channel blocker

NSAIDs produce action through:decrease prostaglandin synthesis
which of the following not characteristic of theophylline:a- relaxation to brochial smooth muscle
b- increase cardiac contractility, CO
c- nausea , abdominal disturbance
e- convulsion
d- sedation
what is drug of choice in ttt of bronchospasm/asthma:a-salbutamol (albutrol )
propranolol

b-theophylline

d-esmolol

e- quinidine

c-

about ophthalmic preparation as single dose which is false:a-sterile

c-should cotain preservative

b- purified
d-..

mechanism of action of antipsychotic drug :

Dopamine receptor inactivation
When concidering drug therapy for hypertention , which is true?
a-combination of drugs always preferred
b-hydralazine is first line therapy in young hypertension
c-furosemide should be administrated before meal to improve
absorption
d-b-blokers should be avoided in asthmatic patient
e- ACEIs are recommended in pregnant women
One of following NOT used to cover bitter taste:a-Film coat
b-Enteric coat
c-Grinding of tablet

which of following tricyclic antidepressant is tertiary amine?

Amitriptyline
antihypertensive used in pregnancy ?
Alpha Methyldopa
( GMP) mean:- Good Manufacturing Practice
a-Good Manufacturing Protocol
b-Good Manu factor Product
c-General Manufacturing Protocol
d-General Manufacturing Product
deltiazem & nifedipine &flocdipine act as
- block Ca to intracellular & increase metabolism from storage site
Which of the following drug has side effect lupus like syndrome :
a- lidocaine

b-minoxdile

c- procainamide

d-hydrochlorothiazide

Ampicilline has similar action of:a- tetracycline

b-cephalexin

c-cloramphinicol

d-amikacine

Amphetamine act as :(INDIRECT-ACTING ADRENERGIC AGONIST)

propencid increase the con. Of penicillin through :a-increase renal tubular reabsorption
b-decrease renal excretion
c-decrease hepatic metabolism
Mecanism of action of Tri cyclic antidepressant:Serotonin & NE Reuptake Inhibitor
Isopretrenol is :a-alpha &beta agonist
c- alpha agonist
e-beta blocker

b-alpha blocker
d-beta agonist

Mechanism of action of echothiophate:( Form stable complex which cholinesterase enzyme )

(Indirect-Acting Cholinergic Agonists )
(Anticholinesterases <irreversible> )
Na picosulfate is used for laxative..
Dopamine is used in cardiac shock as:a) increase lung performance
b) decrease
C.O.P.
c) Don't induce
preiphral vasoconistriction
d) dec.force of contraction
e) selective dilate renal & mesenteric
Verapamil can increase effect of (theophylline &
carbamazepne&digoxin.) as a liver enzyme inhibitor
dipivefrene is:-

epinephrine analoug used in glaucoma

enkefaline as peptide used in :a-electrical conduction as neuron transmitter

b-similar in action to morphine
d-
anextrapyramidal adverse effects is caused by the blocking of:a-Serotonin receptors in the brain
b-Acetylcholine receptors in the brain
c-Dopamine receptors in the brain
d-Dopamine receptors outside the brain
Which of the following are side effects of phenytoin treatment?
a-Acne
b-Hirsuitism
c-Gingival hyperplasia
d-a,b,and c
All These drugs can be used for Parkinsonism except :

a- Selgitine HCL
b- Carbidopa
c- Pergolide
d- Nedocromil Sod.
Cardiac arrest could be managed by the following except :a- Ephedrine
b- LIdocaine
c- Propranolol
d- Normal saline
All These drugs are anti-bacterial except :a- Zalcitabine
b- Lomefloxacin
c- Cefprazone
d- Non of the above
Which one of the following has vasodilator effect :a- Nicotine
b- Cholestyramin
c- urikinase
d- Vit. A
All of the following are controlled drugs except :
a- Rivotril
b- Epanutin
c- Sresolid
d- Diazepam
Which one of the symptoms does not occur with morphine :
a- Diarrhea
b- Respiratory depression
c- Constipation
d- Vomiting
Which one of these drugs is not used for acute pain :a- Naproxen

b- Colchicine
c- Codeine
d- Prednisolone
Which of the following is not cardio specific -blocker?
a Atenolol.
b Acebutolol.
c Satolol.
d Labetalol.
procainamide is like:
a quinidine (anti arrhythmic supra ventricular)
b Nifedipine.
c Lisinopril.
d Cilazapril
New & best therapy for peptic ulcer is:
a Four medicines including antibiotic.
b Use more than H2 antagonist.
c Antacid + H2 antagonist.

in case of osteoarthritis & peptic ulcer of elderly patients use:

a Paracetamol.
b Strong NSAIDs.
c Aspirin.
Drug which decreases [antidote] the action of warfarin is:

a Carbimazole.
b Oral contraceptive.
c Phenobarbitone.
d Vitamin K.
e Give the antidote of each of the following drugs.
Heparin
Paracetamol
Warfarin

-Protomin Zinc.
-Acytylcystiene.
-Vitamin K.

The antidote of heparin available in fish is:

Protamin sulphate.
Hepatotoxicity is induced due to these drugs except:
a Rifampicin.
b Ketoconazole.
c Quinolones.
d Dipyridamole.
The cause of death in morphine toxicity is:
a Respiratory failure.
b Heart block.
c A-V block.
Pseudomembranous colitis is a side effect of:
a Clindamycin.
b Vancomycin.
c Reserpine.
d INH.
All of these are antimetabolites (cytotoxic) except:

a Methotrexate.
b Cytarabin.
c Azathioprine.
d Mercaptopurine.
e Fluorouracil.
f

Cyclophosphamide.
Specific Serotonin reuptake inhibitors are used as:

a Antihistaminic.
b Antidepressant.
c Antihypertensive.
d Anti-emetic.
Fluoxatine (Prozac) is:
SSRI antidepressant.
a Selective Serotonin Reuptake Inhibitor.
b A & B.
Which one is correct?
a Diazepam is not used for long time.
b Diazepam is taken I.M. only.
c Diazepam is derived from morphine.
d Diazepam can cause muscle spasm.
Source of human insulin is E-coli by:
a Biosynthetically by recombinant DNA technology using E-coli.
b Semi synthetically by enzymatic modification of protein material.
c A & B are correct.
The steady state concentration of the drug in the plasma depends
on:
a Direct proportion to the rate of elimination.

b Indirect proportion to the rate of elimination.

c Direct proportion to the rate of administration.
d Indirect proportion to the rate of administration.
Clonididne used in:
a Hypertension.
b Hypotension.
c None of the above.
Sustained release tablets depend on:
PH of stomach.
Treatment with an anti arrhythmic drug depends on the following
except:
a Patient sex.
b Type of medication.
c Period of medication.
d Doctors advise.

electrical property which produce impulses called :

a-conduction
c-velocity

b-automaticity
d- excitability

infusion of hypotonic solution in blood cause :

a) shriniking of blood cell
b) hemolysis
c) hyperglycemia
hypoglycemia
e) b + d
About definition of first pass effect , it increase with:a- increase rate of absorption
b- increase biotransformation
c- increase pka
d- A&B

metal used in rheumatoid arthiritis : gold

in hypodynamic shock treatment we used :a- dopamine

b- nicotine
c- aspirin
Dipivefrine is:a-Anti HTN
c-Glaucoma

b-chelating agent

Which of the following Not occur in digitalis toxicity:a)hypokalemia

b)hypomagnesia
c)hypocalcemia
d)hypothyroidism
e)impaired kidney
function.
( the main cause of digitalis toxicity is
renal failure)
Fifty micrograms equals:
a-50000 ( nanogrames )? b- 0.05 ( milligrams )?
c- 0.0005 g
d- a and b
e- a and c
mc g : 1000 nano g milli g : 1000 mc g g : 1000 mg g : 1000000 mc g
HOW can prepare 100 ml of 12% MgCl by taking?
a-12ml of MGCL dissolve in 100 ml water
b-12 gm of MGCL dissolve in 100 ml water
c-12ml of MGCL dissolve in 1000 ml water
d-90.5 ml of MGCL dissolve in 100 ml water
e-.95 ml of MGCL dissolve in 100 ml water
the dose of drug is 0.5ml per day and the total amount of the drug Is 100ml what is
the total dose ?
sol.= <200 >
The ppm concentration of a 6.35x1 0-6M solution of sucrose (molecular weight of

sucrose is 342.3 g/mole) is:

A. 2.174 X 10-3ppm
B.2.174 ppm
C.2.174gm/ml
C. Both A and B
D. Both Band C
ppm concentration = mass in mg / volume in liters
mass (wt ) = mole * mwt = gm
mass=6.35x10-6x342.3=2.174x10-3gm
mg 2.174= 1000 mg volume=1liter
B.2.174 ppm
the pharmacological property of amphetamine is:
A. Causes release of estrogen.
B. Causes release of stored norepinephrine.
C. Does not cross the blood brain barrier.
D. Causes the release of stored acetylcholine.
E. Metabolized by phosphodiesterase II
.cushing - like syndrome is due to
a) adrenal hyperplasia b) adrenal hypoplasia
c) Hypothyroidism d) hyperthyroidism
The following properties are similar for both solutions and
suspensions:
A. The components of both solutions and suspensions can be
separated from each
other by physical processes. .
8. Solutions and suspensions are composed of two or more
components.
C. Solute in the solutions and suspensions settle out over a period
of time.
D. Both A and B
One of the statement considering Tetracaine
One of neuro muscular blockerIn the ttt of T.BOpioid analgesicVit d metaboliteThe most one of choice in spinal anaesthesia
.The antimalarial to be avoided in glucose-6-phosphate
dehydrogenase deficiency :

a- primaquine
b-quinine
c-chloroqunine
.all of the following are side effects of methotrixate except :
a-Bone marrow depression
b-Alopecia
c-Nausea and vomiting
e-Drive sex gland
This question coming to me and some for other groups in the same day
Re Check all answers Yourself & the Best of Luck