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ensures isoionic, isotonic and isoosmotic balance in the ground substance. Each change in
the ground substance will change the electrostatic field through oscillations of potential.
These oscillations of potential, if strong enough, lead to a cell reaction through
depolarization of the cell membrane.
In other cell types information is transmitted to cytoplasmatic enzymes by messenger
substances, which are present in the cell membrane.
The information which arrives in the cell nucleus is translated into cell-specific products
by appropriate parts of the genetic code.
The fibrocyte is the regulatory centre of the ground substance. Only the fibrocyte is able
to synthesize a ground substance which is appropriate to the situation. The glycocalix,
the fuzzy cell-sugar coat is extremely important for the transmission of information to
and from the cell. Together with the glycoproteins and the structural glycoproteins they
are the most important information filters and mediators. The ground substance is
connected with the endocrine gland system through the capillaries. Furthermore, the
peripheral autonomic nerve fibres end in the ground substance. Both systems are
connected with each other in the brain stem. The "free" connective tissue cells, such as
mast cells, macrophages, leucocytes, influence each other through released cell products,
such as for example prostaglandins, interleukins, interferons, proteinases. This results in
a highly complex interwoven humoral system.
The psyche is another important factor in this reticulum.
Through being able to transmit and store information by binding water and exchanging
ions, the ground substance is responsible for regulating homoeostasis.
Special interest should be paid to the frequent formation of radicals which take place due
to electron and proton changes occurring during oxygen metabolism.
The physiological redox potential receives the resulting energy via the ground substance.
In the case of circulation disturbances radicals can accumulate and unphysiological
changes of the redox potential of the ground substance take place.-In 1983 Pischinger
and Perger reported that chronic inflammatory diseases and even tumours can develop if
these disturbances are prolonged.
Greater interest should be paid to another function of the ground substance.
Proteoglycans are able to store nutrients: carbohydrates as glucose and galactose,
protein as -NH-groups, fat as carbohydrate chains with residual acids and water, with
water being the most important nutrient. If water content is reduced the proteoglycans,
which are originally brush-shaped, fold up and impair the transit routes in the ground
substance.
In my opinion it is not widely enough known that soft water with high electrical resistance
is healthier than hard water. Of course it has to be water low in minerals or water where
surplus minerals have been extracted by inverted osmosis.
Wendt has proven that, contrary to the existing doctrine, the organism can store protein
in the form of collagen, proteoglycans and glycosamine glycans in the ground substance.
If the capacity - different in each individual - to catabolise the deposits is disturbed, the
transit routes are increasingly transferred and, among other things, micro- and
macroangiopathies develop.
Wendt also reports that the ratio of collagen to polysaccharides in storage protein is 95%