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Drawing
Generic Name
Brand Name
Classification
Action
Dosage
Indication
Contraindication
Side Effects
Adverse Effects
Drug Interaction
Nursing
Interventions
Drawing
Generic Name
Brand Name
Classification
Action
Dosage
Indication
Contraindication
Side Effects
Adverse Effects
Drug Interaction
Celecoxib
Celebrex
NSAID, Analgesic (nonopioid), Specific COX-2 enzyme blocker, Pregnancy Category C (first and
second trimester), Pregnancy Category D (third trimester)
Analgesic and anti-inflammatory activities related to inhibition of the COX-2 enzyme, which is
activated in inflammation to cause the signs and symptoms associated with inflammation; does
not affect the COX-1 enzyme, which protects the lining of the GI tract and has blood clotting and
renal functions.
200mg PO BID
Acute and long-term treatment of signs and symptoms of rheumatoid arthritis and
osteoarthritis
Reduction of the number of colorectal polyps in familial adenomatous polyposis (FAP)
Management of acute pain
Treatment of primary dysmenorrhea
Contraindicated with allergies to sulfonamides, celecoxib, NSAIDs, or aspirin;
significant renal impairment; pregnancy (third trimester); lactation.
Use cautiously with impaired hearing, hepatic, and CV conditions.
chest pain, weakness, shortness of breath, slurred speech, problems with vision or
balance;
black, bloody, or tarry stools;
coughing up blood or vomit that looks like coffee grounds;
swelling or rapid weight gain;
urinating less than usual or not at all;
nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored
stools, jaundice (yellowing of the skin or eyes);
skin rash, bruising, severe tingling, numbness, pain, muscle weakness; or
severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your
eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face
or upper body) and causes blistering and peeling.
CNS: Headache, dizziness, somnolence, insomnia, fatigue, tiredness, dizziness,
tinnitus, ophthamologic effects
Dermatologic: Rash, pruritus, sweating, dry mucous membranes, stomatitis
GI: Nausea, abdominal pain, dyspepsia, flatulence, GI bleed
Hematologic: Neutropenia, eosinophilia, leukopenia, pancytopenia,
thrombocytopenia, agranulocytosis, granulocytopenia, aplastic anemia, decreased
hemoglobin or hematocrit, bone marrow depression,menorrhagia
Other: Peripheral edema, anaphylactoid reactions to anaphylactic shock
Drug-drug
Increased risk of bleeding if taken concurrently with warfarin. Monitor patient closely and
reduce warfarin dose as appropriate
Increased lithium levels and toxicity
Nursing
Interventions