Revista Boliviana de Qumica

Rev. Bol. Quim. ISSN 0250-5460

Rev. boliv. quim. ISSN 2078-3949

Bolivian Journal of Chemistry

Vol. 32, No. 3, 2015
Abstracts Rsum
SYNTHESIS OF ALKENES BY OXIDATIVE DECARBOXYLATION OF CARBOXYLIC
ACIDS; MECHANISTIC VIEWS; THE ORGANIC CHEMISTRY NOTEBOOK SERIES, A
DIDACTICAL APPROACH, N 6
Jos A. Bravo, Jos L. Vila*
Department of Chemistry, Laboratorio de Sntesis y Hemisntesis, Laboratorio de Fitoqumica, Instituto de
Investigaciones en Productos Naturales IIPN, Universidad Mayor de San Andrs UMSA, P.O. Box 303,
Calle Andrs Bello s/n, Ciudad Universitaria Cota Cota, Tel. 59122792238, La Paz, Bolivia.
joselu62@hotmail.com, jabravo@umsa.bo

Keywords: Organic Chemistry, oxidative decarboxylation, carboxylic acids, Alkenes,

Mechanisms of Reactions.

ABSTRACT
This is the sixth chapter in the series published by the same authors: The Organic Chemistry Notebook Series, a
Didactical Approach.
Here we offer the mechanistic views of the synthesis of alkenes by oxidative decarboxylation of carboxylic
acids. The aim of this series of studies is to help students to have a graphical view of organic synthesis reactions
of diverse nature. The oxidative decarboxylation of carboxylic acids is a useful method for generating alkenes.
Here we propose the mechanism and its discussion for the application of the method of decarboxylation of
diacids lacking nearby double bonds. Also, the route is explained mechanistically for the preparation of Dewar
benzene. The thermal or photolytic decomposition of di-t-butyl per-esters is described. The treatment of
monocarboxylic acids to afford alkenes in the presence of lead tetraacetate and copperII acetate is briefly
discussed. The alkylation-decarboxylation of aromatic acids is also explained. The oxidative decarboxylation of
carboxylic acids can eventually conduct to the obtaining of ketones instead of alkenes. We have used a series of
reactions reviewed by W. Carruthers, and we have proposed didactical and mechanistic views for them. This
latest approach is included in the synthetic methods reviewed by W. Carruthers with respect to the Formation of
carbon-carbon double bonds. Spanish title: Sntesis de alquenos por descarboxilacin de cidos carboxlicos; vistas mecansticas;
De la serie: El cuaderno de notas de qumica orgnica, un enfoque didctico, N6.

*Corresponding author: joselu62@hotmail.com

SYNTHESIS OF THE ANTI-CANCER CARBOPLATIN OXIDIZED, AND STUDY OF ITS

INTERACTIONS WITH N-BASES BY CYCLIC VOLTAMMETRY
Blas P. Puma C.*, Carmen A. Vega O., Mayra E. Cdiz, Enrique Melendz
Departamento de Qumica, Laboratorio de Electroqumica, Universidad de Puerto Rico, Recinto Universitario
de Mayagez, PO BOX 9019, PR 00681-9019, Tel. 787-8324040 ext. 3736, USA. quimblas@hotmail.com,
carmenamarilis.vega@upr.edu

Keywords: Oxidized-carboplatin, Nitrogenous bases, Gold electrode, Potentials, Adducts

ABSTRACT
The anticancer drug cis-diammine-(1,1-cyclobutanedicarboxylate)-trans-dihydroxyplatinum (IV) or carboplatinoxidized was synthesized with 98% purity by oxidizing the carboplatin Pt (II) with hydrogen peroxide 30%.
The elemental analysis was confirmed by Atlantic Microlab Inc. Company (Norcross-Georgia, USA). The study
of the electrochemical behavior of CBDCAOX interacting with nitrogenous bases was performed in a range of 200 mV to -700 mV with a voltammetric analyzer BAS 50W model. The free CBDCAOX voltammogram
showed a reduction signal in -625.4 mV and during the interaction with thymine the signal shifted to less
negative potentials. This result indicates the formation of a strong bond in CBDCAOX-thymine complex. Spanish
title: Sntesis del anticanceroso
voltametra cclica.

carboplatino oxidado y estudios electroqumicos de sus interacciones con bases nitrogenadas por

*Corresponding author: quimblas@hotmail.com

KINETICS OF CHROMIUM(III) UPTAKE BY NOSTOC SP. ALGAE

Edgar Coronel C. *1, Miriam Varela N.2
1

Department of Chemistry, Facultad de Ciencias Puras y Naturales, Universidad Mayor de San Andrs, IIQ,
P.O. Box 303, Calle Andrs Bello s/n, Ciudad Universitaria Cota Cota, Tel. 59122792238, La Paz, Bolivia.
edgar-coronel@daad-alumni.de

Department of Chemical Engineering, Facultad de Ingeniera, Universidad Mayor de San Andrs,

IIDEPROQ, Calle Andrs Bello s/n, Ciudad Universitaria Cota Cota, Tel. 5912774412, La Paz, Bolivia

Keywords: Nostoc algae, Absorption kinetics, Chromium biosorption

ABSTRACT
An alga arising from Lake Titicaca basin (Bolivia, South America), has been studied faced with adsorption
kinetics of Cr(III). The samples of Nostoc sp. were put in contact with chromium (III) solutions at 18oC. The pH
effect has been measured from 2.50 up to 5.40. Concentration-time profiles shown exponential functions or first
order processes. There is a linear relationship between pH and rate constants ko from 8.0x10-3 min-1 to 8.3x10-2 min1
. At low pH, metal adsorption is negligible and maximum at high pH. Different initial concentrations of Cr(III),
yielded also first order rate constants between 2.9x10-2min-1 and 5.0x10-3min-1. Hydrogen ions would be competing
against metal ions in order to achieve active sites. As possible mechanisms, not only the ion exchange could be
involved, but also complex compound formation. Spanish title: Cintica de la absorcin de cromo(III) por algas Nostoc sp.
*Corresponding author: edgar-coronel@daad-alumni.de