1.

High Pressure in Glomerular cappilaries is due to

a. Afferent is long
b. Afferent is short
c. Efferent is low resistance
d. Efferent is down stream
2.Regarding SLE followin are true except
a. ANA is +ve
b. Fibrinoid necrosis is common histological feature
c. Glomerulonephritis is commonest cause of death
d. more common in women
e. risk is increased by inheritance of HLA B27
3.Edema in nephrotic syndrome
a. Na retention
b. Hypoproteinemia
c. Hyperlipidemia
4.Bronchopulmonary segment
a. each has its own blood supply
b. different number on both sides
5.Recently diagnosed fatal disease, most appropiate
a. tell family but nt patient
b tell patient but nt family
c. tell family and patient as soon as knwn
d. crisp, logical and evidence based accurate information to the patient and family
accordin to demand
6.Young lady having anemia, MCV 78 , MCH 25, MCHC 29
a. Hypochromic
b.Hypochromic and Normocytic
c.Hypochromic and microcytic
d. normocytic and normochromic
7.WHICH OF THE FOLLOWING SHIFTS THE O2-HGB

DISSOCIATION CURVE TO RIGHT:

A.ACIDOSIS
B.ALKALOSIS
C.INCREASE pH
D. NO
E. FETAL HEMOGLOBIN
8.A 75 year old man with an acute MI suddenly dies 6 days after the infarct . At
autopsy, there is a
large amount of blood in the pericardial sac . The most likely cause of death is ;
A. Cholesterol pericarditis
B. Amyloidosis
C. Cardiac tamponade
D. Codsackie B pericarditis
E. Constrictive pericarditis
9.most active gluconeogenesis results from
metabolism of ?
a.fatty acid
b.protein
c.cholesterol
d.glycogen
e. TG
10. Severe magnesium deficiency
a. Hypocalcemia
b. Hypercalcemia
c. Hypokalemia
d.Hypophosphatemia
11. Langerhans giant cells found in
a.Tuberculosis
b.Sarcoidosis
c.Wegners granulomatosis

D)Syphlis
12. parasympathetic inervation
a.sweat gland
b.salivary gland
13. A pt has multiple polyps on
colonoscopy.His father died of same
disease.These types of polyps are
a-Hemartomatous
b-Adenomatous polyp
c-Metaplastic
14. Dysarthria is due to a lesion in?
a.Brocas area
b.Cerebellum
c.Thalamus
d.Sensory motor cortex
e.Hypothalamus
15. After 2 liter loss of fluid through sweating, which fluid should be given to replace
the fluid loss of
this person?
A. 5% dextrose
B. 0.9% N/S
C. 10% dextrose
16. During 2nd week which is appropriate test for
Typhoid fever ?
a) Widal+Blood culture
b) Blood culture only
c) Stool culture only
d) Bone marrow
17. A woman havin fever for few days developed chest pain which aggravated by
lying down . Reason
is?

a.Costochondral junction
b.Mi
c. pericarditis
d.due to plurea
18. purpura is most likely asaociated with
a. leukemia
b. von wilbrand disease
c. hiv
19. a lady using diethylesterbestrol wht should be most likely in her daugter
a. squamous cell carcinoma
b. clear cell carcinoma
20. Lady with osteoporosis,having family h/o cardiac disease and breast ca. Treated
by
a. Calcium plus vit D
b. Raloxifene
c. bisphosphonates
d. HRT
21. Which disease involves a carrier stage ?
a.Measles
b.Mumps
c.Polio
d.Typhoid
22. H+ ion
secretion in proximal tubule is related with?
A. Bicarbonate reabsorption
B. Bicarbonate excretion
C. K secretion
D. Na secretion
23. Hamartoma is ;
A. A Metaplasia

B. A neoplasia
C. Has a capsule
D. Same as cholestoma
E. Totally benign
24. 40 yr old woman,middle class,3 kids,pap snear shows cervical dysplasia..cause
A HPV
B IUCD
25. 10% Formaldehyde is used for sending Biopsy
specimens,Why?
a. Sterilisation
b.To prevent autolysis
c. TO stain cells
d. TO denature proteins
e. to cause lysis of cell
26. Metastatis occur in all except
a.Liver
b. Brain
d. Spleen
d. lung
27.Fast, sharp pain from mechanical origin is mediated by which fibers;
A. A alpha
B. A delta
C. C fiber
D. High myelinated
28. Fat necrosis occurs in ;
A. Acute pancreatitis
B. Heart
C. Liver
29. Which tumor is derived from all the 3 germ layers;
A. Adenoma

B. Teratoma
C. Rhabdomyosarcoma
D. Chancroid
30. A 20yr old male has dyspnea on lying down. The structure most likely to cause
this is ;
A. Enlarged isthmus of thyroid
B. Puberty
C. Retrosternal goiter
31. A FISHER MAN PRESENTED WITH SLOWLY DEVELOPING LETHARGY, EASY
FATIGUE AND
PALPITATIONS. HIS DIET COMPRISES OF FISH AND RICE MOSTLY PHYSICAL EXAM
SHOWED PALLOR
AND LOSS OF TOUCH SENSATION IN BOTH FEET AND LOWER LIMB. HIS CBC
SHOWED HB 7.5G/DL MCV
132, PLATELETS 110 AND WBC 3450 . MOST LIKELY CAUSATIVE PARASITE:
A.ANKYLOSTOMA DUODENALE
B.DIPHYLLOBOTHRIUM LATUM
C.STRONGYLOID STERCOLIS
D.ECHINOCOCCUS GRANULOSIS
E. TAENIA SAGINATA
32. Long term elevated BP is due to
a.cardiac output
b.renal function
c.TPR
33. The vitelline duct forms;
A. Ductus venosus
B. Duodenum
C. Meckel, s diverticum
D. Portal vein
E. Urachus
34. Which is correct Regarding Axillary artery

a-It Lies behind pectoralis minor

b-Extend upto the lower border
of pectoralis major
35. a. the components of the cell containing microtubules in there structure are;
a. cell membrane
b. centrioles
c. endoplasmic reticulum
d. lysosomes
e. mitrochondria
36. a chronic smoker from 30 years woorking in a tyre factory presented with
painless hematuria n on
histopathology transitional cell carcinoma of bladder causative agent is ..?
a.aromatic amines
b.tobaco smoking
c.nitrites/nitrates
d.shistosomia hematobium
37. most common manifestation of autoimmune
disease ;
a. Fever
b.arthralgia
c.haematologic symptoms.
d.fatigue
38. ACTH effectively controls ?
a. Aldosterone
b. Adrenal androgens
c. Adrenal estrogen
d. Hydrocortisone
39. what defines the acute inflammation ?
1.local response of living tissue to injury
2.systemic response of living tissue to injury

3.migration of leukocytes
40. aortic pressure lowest during which phase of cardiac cycle??
a.atrial systole
b.isovolumic cobtraction
c.isovolumic relaxation
41. The vision lost is left temporal and right nasal field of both eyes, the visual
pathway involved in
this lesion is
A. Rt optic nerve
B. Left optic tract
C. Rt optic tract
D. Left optic nerve
42. the affect of L dopa in parkinson pt dcreease gragually due to
1.antibodies develop against l dopa
2.gradual degeneration of neurons in sunstantia nigra
43. Glucose transport across a membrane is directly proportional to concentration
graddient . Type of
transport is ;
A. Simple diffusion
B. Facilited
C. Active
D. Na countertaransport
44. sebacous glands are absent on
1.corner of lips
2.palms
3.glans of penis
45. Blood transfusion reaction is likely to occur when a person having blood group
A+ is transfused
with blood of group;
A. A+
B. AC. ABD. O+

E. O-46. C0mplicti0n of diabetic?

a.Wet gangren
b. dry gangren
c. ranyod phen0mena
d. thrmbroagints
47. true regarding genetic inhertance of SLE is ;
a. high incidence in monozygotic twins
b. incidence is high in females
c. if its in family, more chances to occur to all family members
48. Langhans giant cells are found in;
a.Tuberculosis
b.Sarcoidosis
c.Wegners granulomatosis
d. Leprosy
49. most active gluconeogenesis results from metabolism of ?
a.fatty acid
b.amino acids
c.cholesterol
d.glycogen/carbohydrates
50. Esophago gastric junction competence is
maintained by
A. lying supine
B. increased intra abdominal pressure
C. diaphragm paralysis
D. use of metoclopramide
E. use of morphine
51. Diminished jaw jerk due to lesion of
A. Mesencephalic nucleus of V nerve
B. Facial motor nucleus
C. Glossophyrngeal injury

D. Vagus injury
52. Co-trimoxazole action in.hiv pt on pnumocystc carini?
a.Inhibit cellwall syn
b.Inhibit folic acid synth
c. inhibit DNA synth
53. Which of the following structure doesn't pass posterior to the flexor retinacum
A. Ulnar nerve
B. Median nerve
C. Flexer digitorum superficialis
D. Flexer digitorum profundus
54. Cardiac surgeon during open heart surgery found bleeding vessel accompanying
LAD in anterior
interventricular groove . Most likely involved vein is ;
A.Great cardiac vein
B. Anterior cardiac vein
C. Oblique vein
D. Small cardiac vein
E. Marginal vein
55. An upper motor lesion of facial nerve will result in ;
A. Excessive lacrimation
B. Hyperacusis
C. Loss of taste sensation in ant 2 /3 of tongue
D. Ability to wrinkle the forehead on the affected side
56. SQUAMOUS CELL CARCINOMA
a.Actinic keratosis
b. marjulian ulcer
57. Regarding histology of gastrointestinal tract, which is inappropriate ;
A. Peneth cells contain Eosinophilic granules in apical cytoplasm
B. Peyer's patches are present in submucous layer of duodenum
C. Parietal cells of human stomach secretes intrinsic factor

D. Striated brush border is composed of microvilli

E. The longitudinal coat of muscularis externa is arranged in 3 bands in colon
58. Which one.is.malignant
a.Glioma
b.Meningioma
c.Psedolymphoma
d.Chondroma
59. which cranial nerves r parasympathetic
A. III, VII, IX, X
B. V, VIII, II, XII
60. Severly dehydrated man comes in er what to gv
a.5percent glucose
b.Ten precent glucose
c.Hypertonic albumin
d. 0.9% nacl
61. Fibrous dysplasia commonly occurs in
a.Maxilla
b.Occipital bone
c.Frontal bone
d.Temporal bone
62. Weight of prostate
a.14 gr
b.24 gr
c.30 gr
d.40 gr
63. Edema is caused by;
A. hydrostatic pressure
B. osmotic pressure
C. Lymphatic obstruction
64. Growth hormone secretion is increased ;

A. Exercise
B. Hperglycemia
65. Drug action wont b affected bound to alpha
glycoprotein in
a. Neoplasm
b.Trauma
c. Hepatic disease
d. MI
66. Clinically GFR is measured by
a. Creatinine
B. Inulin
67. 16 yr child with cola color urine since one day , Hb 6 , high grade fever , was
given antimalarial 1
day back ..
a.g6pd
b.falciparum(blackwater fever)
c. PNH
68. The cause of death in gas gangrene is due to ;
A. Bacteremia
B. Toxic shock
C. Pneumonia
69. which is not the content of mediastinum...?
a.lungs
b.heart
c.trachea
d.vagus nerve
e.large vessels
70. Diseases transferred thru vertebrate animals to
humans:
a)zoonosis

b)zonoarthosac
c)Zoncosis
d) anthropozoonosis
71. about calcitonin...?
a.must b given parenteral
b.may b used in intoxication of vid D
c.hypoparathroidism
d.a polypeptide of 32 aminoacid
72. most common conginital heart dsz?
a)asd
b)vsd
73. A man with AIDs who has no symptom with CD4 count 800 presented with
suppurative otitis
media, causative organism is:
A. Mycobacterium
B. Strep pneumoniae
C. Pseudomonas aeruginosa
d)stap aureus
74. A pt can survive without mechanical ventilation, if the lesion is ;
A. Above C2
B. At C3
C. At C4
D. Below C5
75. Preganglionic sympathetic nerve fibers release ;
A. ACH
b. Norepinephrine
C. Dopamine
76. A man died 5 days after MI and large blood clots was found in pericardial sac .
He died due to ;
A. Pericardial tamponade
B. Viral infection

C. Kawasaki disease
77. Which one of the following is a COX II inhibitor ;
A. Aspirin
B. Indomethacin
C. Meloxicam
78. Fasting blood sugar of pt is 6.8 mmol (122 mg/dl) after 1 hr of OGTT it is 10.9
mol and later after 2
hr postprandial it was 10.7 mol ( 194 mg/ dl ) what is the diagnosis
A. DM
B. impaired glucose tolerance
C. Long lag phase
79. Not recorded on ECG normally
a.SA NODE
b.LEFT ATRIUM
c.AV NODE
d.RIGHT ATRIUM
80. After 48 hr of starvation, wht will be broken down to provide energy,;
A. Carbohydrate
B. Fat
C. Protein
81. Which of the following causes increased interstitial pressure;
A. capillary permeability
B. colloid osmotic pressure
82. Post op wound causes greenish pus discharge . Which organism is involved ;
A. Psudomonas
B. Klebseilla
C. E. Coli
83. Infection spreads retroperitoneally, which will b infected
a) Spleen
b) Jejunum

c) Transverse colon
d. Ascending colon
84. Sprain of ankle leads to eversion of ankle, which ligament is damaged .
a. Deltoid
b. Talofibular
c. peroneal
d. tendocalcaneous
85. A pt, wd DK didnt respond to treatment and died, Autopsy show inflammatory
lesion in kidney
brain and lung, with some fungus. Most likely organism is ;
A. Mucormycosis
B. Candida
86. Person naked in room, temperature 21 degree centigrade, humidity present, loss
of heat by ;
A. Insensible perspiration
B. Sweating
C. Conduction and radiation
87. Microscopic feature of polyarteritis nodosa is ;
A. Granuloma
B. Fibrinoid necrosis
C. Associated with hepatitis c
88. Which of the following structure damages in thyroidectomy ;
A. Recurrent laryngeal nerve damage
B. External laryngeal nerve damage
C. Laryngeal oedema
D. Sore throat
E. Vagus nerve damage
89. ACTH effectively controls ?
a.Aldosterone
b.Adrenal androgens
c.Adrenal estrogen

d.Hydrocortisone
e.NE
90. which cannot b measured by spirometry
1.residual volume
2.expiratory reserve volume
3.inspiratory reserver vol
4.tidal vol.
91. the following diseas occur in iv abuser
1)infective endocarditis
2)llibmansack endocarditis
92. Normal FEV1/ FVC ratio is ;
A. 0.6
B. 0.8
C. 1
D. 5
93. Pt unable to void after fall which of the following section of spinal cord is
affected;
A. L2, L3, L4, L5
B. L1, L2
C. S1, S2, S3
D. S2, S3, S4
94. osmotic diuretic effects on which part of nephron
a.proximal tubule
b.collecting duct
c.asc loop of henle
d.glomerular memb
95. After rapid loss of 2 liter of fluid . person drinks plain water . it ll lead to
A. Increase in interstitial fluid only
B. Increase in intracellular fluid
C. Plasms volume increase

96. A patient known smoker in laryngoscopy found laryngal nodule what is most
unlikely
1 neoplasm
2 hyperplasia
3 keratosis
4 atrophy
97. secondary center of ossification
a.epiphysis
b.epiphyseal plate
c.diaphysis
98. .liquefactive necrosis.
a.brain
b.kidney
c.spleen
99. 1st heart sound
a.isovolumetric contraction
100. A 40 year old man has pain felt deep in the face and nose between the mouth
and orbit to the
ear and temporal region . the pain may be due to the lesion of the ;
A. auricular nerve
b. facial nerve
c. hypopharyngeal nerve
d. maxillary branch of the trigeminal nerve
e. opthalmic branch of the trigeminal nerve
101. EBV
nasopharyngeal carcinoma
102. inverse stretch reflex(resulting relaxation)
golgi tendon organ
103. fast sharp pain
A delta fibers
104. 3rd ventricle

bounded laterally by 2/3 thalamus

105. glycogen breakdown
aerobic and anaerobic break down to pyruvate
106. fatty acids co enzyme
biotin
107. %age
units/total units X 100
108. The diagnostic lab test for the infection by streptococuss beta haemolyticus is ;
A. ASO titre
B. Blood culture
C. ESR
D. Leukocytes culture
E. Urine for bile pigment
109. disclosing pt's secret info
only with pt. consent
110. Most common cause of inc bleeding time
a.thrombocytopenia
b. Aspirin
111. opsonin
C3b
112. plasma cells
antibodies
113. black water fever
a.p.falciparum
114. hamartoma
a.beningn
115. alkalinize urine for removing
a.phenobarbitone
116. parasympathetic sys
a.inc the AV nodal delay

117. .parasympathetic action

a. sweat glands
b.salivary glands
118.ectopic pregnancy
a. uterine tube
119. both central n peripheral chemoreceptors respond to
a..arterial pCO2
120. meckel's diverticulum
a.vitelline duct
121. .insulin dec by
a.beta blockers
122. most sensitive cardiac marker
a.trop T
b.Ckmb
123. Hypothyroidism
a. increased TSH
124. left adrenal vein drain into
a.left renal vein
125. fastest b.p regulation
a.baroreceptor
126. ESR inc in
a.infections
b. polycythemia
127.local factor delaying wound healing
a.foreign body
b. local infection
128.actin covered by
a.tropomyosin
129. turner
a.44xo

130.klinefilters syndrome
a.46XXY
131. S2,S3,S4 lesion
a.rectal incontinence
b.no pain in labour
c. anorgasmia
132. pain referred to shoulder
a.c2c3
b.C3,C4,C5
133. compression of S1
a.dec ankle jerk
134. not related to rt. kidney
a.descending colon
135. external carotid
a.lateral to retromandibulr vein
136.symphisis pubis
a.sec. cartilaginous joint
137.fibrous and parietal pericardium supplied by
a.phrenic
138. corona radiata
a.granulosa cells
139. .cimetidine with sucralfate
a.decrease metabolism
b. Sucralfate decreases cimetidine absorption, give it after 2 hours
140. Cimetidine may significantly prolong the prothrombin time and causes
bleeding in pt who has
been treated with warfarin by ;
A. decreasing the hepatic clearance of warfarin
B. Displacing warfarin from plasma protein
C. Increasing the oral bioavailability of warfarin

D. Inhibiting renal tubular secretion of warfarin

141. .sternocleidomastoid supplied by
a.accessory nerve
142.regarding collagen
a.present in all types of connective tissue
b.unique protein
145.organ for metabolism
a.liver
b kidney
146. Regarding Portal vein following statement are correct ; Except
A. Develops partly from the cranial part of right vitelline vein
B. is connected to veins of anterior abdominal wall through paraumbilical vein
C. Is formed by union of superior and inferior mesenteric vein
D. lies in the free margin of lesser omentum
E. tributaries include left gastric and superior pancreatoduodenal vein
147. compact bone...
a.Regularly arranged lamelae
148. An initial left to right shunt before reversal is most commonly a feature of ;
A. Coarction of the aorta
B. Ebstein' s malformation
C. Eisenmenger's complex
D. Transpostion of the great arteries
E. Truncus arteriosis
149. Digoxine unlikly
1.inc Ca intracellular
2.inc K intracellular
3.inc Na intracellular
4.inc sympathetic to heart
150. u wave is associated with
1.atrial depo

2.atrial repo
3. ventrlr repor
4. ventricl depo
5. slow repolarization of papillary muscles
151. A 25year old sprinter developed acute leg pain while running. the next day he
noticed
ecchymosis around ankle . he can stand on his toes through it hurts . the most likely
cause is ;
a. acute arterial embolism
b. deep vein thrombosis
c. herinated lumbar disc
d. ruptured Achilles tendon
e. ruptured plantaris tendon
152.A 30 year male came to a consultant clinic with history of progressive right
facial numbness and
headach for 3 months, on examination, facial nerve palsy was confirmed on right
side along with VIII
nerve involvement of same side, and right sided Intention tremors, the most likely
site of lesion is ;
A. Cerebello pontine angle
B. Pons
C. Rt lobe of cerebellum
D. Rt side of mid brain
153. Wilsons disease
A. Ceruloplasmin
154. 16 yr old boy with diarhea,biopsy showin villous atrophy, not improved by
gluten free diet, most
likely diagnosis
a. Celiac disease
b. Giardiasis
c. Whipples disease
155. IM ketorolac given in

a. Renal failure
b. Pregnancy
c. Suspected drug addicted complaining of pain
156. Water and salt reabsorption is maximum at
a. Duodenum
b. Stomach
c. jenunum
d. Ileum
e. Colon
157. wht happens in patient gettin TPN
a. Hyperglycemia
b. hyperphospatemia
158. epinephrine given slowly???
a.Something to with TPR
159. Premalignant oral lesion
a. Lichen planus
b. Submucosal fibrosis
160. Question from biostatistics
a.statistical data is of no significance
b. Chi square
160. Failure of aorta to separate from Pulmonary artery
a. Truncus Arteriosus
b. TOF
161. Nerve loops around arch of aorta
A. recurrent laryngeal nerve
162. Hemolytic anemia question??
163. in tabes dorsalis which is destroyed??
164. Toxoplasmosis
a. Parasite
165. transmitted from eating undercooked meat

a. tapeworm
b. Liver fluke
166. false statement about Carbimazole
a. increases T4 to T3 conversion
167. lady with exophthalmos, thyrotoxicosis
a. Graves
b. MNG
168. Mitral stenosis, absent waves are
a. c waves
b. a waves
169. What wil decrease in hypotension
a. Carotid sinus discharge
170. RBC fragility
a. 0.35 % NaCl cause hemolysis
b. Hypotnonic cause swelling
c. Hypertonic causes shrinkage
171. Standing from 1 hour
a. Decrease CVP
172. something about Gamma motor neuron
a. Relaxes muscle
b. controls fiber 1a afferent
173. Arteriolar dilation leads to
a. increase in arterial blood volume
b. increase in venous volume
c. something about capillaries
174. Cause of Squamous Cell Carcinoma bladder
a. Shchistosoma hematobium
175. Not true abt sulfonylurea???
176. Sjogrens Syndrome
a.dry mouth and eyes

b. Dry mouth only

c. Dry nasal mucosa
177. Which one is not epithelial tumour
a. Adenocarcinoma
b. Liposarcoma
c. Squamous cell Ca
178. Diphtheria toxoid given n thn aftr 2 weeks skin rashes , most likely reaction
a. Type 1
b. type 2
c. Type 3
d. Type 4
179. Cardiac output low in
a. beri beri
b. Cardiac failure
c. AV fistula
d. hyperthyroidism
180 Labetalol
a. Beta blocker
b. Alpha blockr
c. Alpha plus Beta blocker