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TEST AP101-4
Immune System
Questions:
96 Multiple-Choice Questions
Test Duration:
115 minutes
Reading Time:
10 minutes
INSTRUCTION:
Only Bilingual Dictionaries allowed, NO NOTES. This test consists of one part, 185 multiple choice questions
(numbers 1 to 185) to be answered on the computer answer sheet (185 marks). Write your name and student
number in the spaces provided on the computer answer sheet. Carefully fill in the shapes on the computermarked answer sheet under your name and ID number with a 2B pencil. You must only use a 2B pencil on the
computer answer sheet. Please read the instructions on the answer sheet carefully and follow them precisely.
Select the best answer to questions. If you are unsure of an answer, eliminate the alternatives that you know
to be incorrect and select answer from the remaining alternatives. To indicate your selection, use a 2B pencil
to blacken the corresponding oval on the computer answer sheet, AP101-1. No marks are deducted for wrong
answers. So students are advised to move on quickly without wasting too much time on one question. Advanced questions; require further reading or online research.
1,2
2, 3
1,2,4
2,3, 5
10
2, 7, 5, 6, 3, 1, 4
7, 2, 5, 3, 6, 1, 4
2, 7, 4, 3, 6, 1, 5
7, 2, 4, 6, 3, 1, 5
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81. Which of the following is considered to be a major component of the second line of defence?
A. phagocytes
B. inflammation
C. cell-mediated immunity
D. both B and C
82. Which of the following incorrectly matches the antibody and its characteristic?
A. IgG; most abundant class of antibodies
B. IgM; antigen receptor found on B cells
C. IgD; found in saliva and for this reason, known as secretory IgD
D. both B and C
83. Which of the following is mismatched?
A. B cells: can be activated to produce antibodies
B. helper T cells: directly target and kill cancer cells
C. regulatory T cells: release inhibitory cytokines to dampen the immune response
D. cytotoxic T cells: carry out cellular immune responses
84. The influx of plasma fluid by inflammatory response:
A. dilutes bacterial toxins
B. activates plasma protein systems
C. causes oedema
D. all of the above
85. Which of the following is brought to the injured site by inflammatory response?
A. clotting proteins
B. plasma fluid
C. inflammatory mediators
D. all of the above
86. In acute inflammation, the main initiator of both increased vascular permeability and vasodilation is:
A. prostaglandins
B. kinins
C. histamine
D. leukotrienes
87. Swelling of lymph nodes may indicate:
A. infections
B. sore throat
C. breast cancer
D. all of the above
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88. Which cells of adaptive immune system protects the body against external cellular threats?
A. helper T cells
B. B lymphocytes
C. cytotoxic T cells
D. natural killer cells
89. The primary humoral immune response has a lag period about 3-6 days because:
A. antibody production by plasma cells is a slow process
B. only few B cells are specific for the antigen
C. antigen has to penetrate the first line of defences
D. both A and B
90. Which of the following type of vaccines most strongly provokes the immune response?
A. inactivated
B. live-attenuated
C. subunit
D. toxoid
91. Which of the following produces the mucus that traps microbes and irritants in airway?
A. ciliated epithelial cells
B. squamous epithelial cells
C. goblet cells
D. plasma cells
92. Which of the following occurs during asthma attacks?
A. mucus hypersecretion
B. bronchoconstriction
C. both A and B
D. none of the above
93. In the absence or destroyed helper T cells, which of the following is most likely to occur?
A. increased risk of viral infections and cancer development
B. increased risk of tissue damage
C. increased risk of opportunistic infections
D. both A and C
94. Which of the following correctly matches the antibody type is present in the mucus in the upper
respiratory airway, with its roles?
A. IgA protects against bacteria, virus and toxins trapped in the mucus
B. IgG triggers mast cells to release inflammatory mediators
C. IgA helps immune cells to recognise foreign materials in the mucus
D. IgG protects against bacteria, virus and toxins trapped in the mucus
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95. Which of the following event would trigger the second line of defence?
A. antigen presentation in lymph nodes
B. when skin or mucosa is breached
C. when body cells burst, releasing its enzymes that damage the tissue
D. both B and C
96. Which of the following cell is not an antigen presenting cell?
A. neutrophil
B. macrophage
C. dendritic cell
D. B lymphocyte
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