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PHARMACOLOGY
Please use a dark pencil/pen to complete the test. Read the instructions at the
begining carefully. This is an Sample Test Paper for practice.
Please Note: There is a Negative Marking of (-1) for each incorrect response.
1. Drugs that reduces the bioavailability and absorption of warfarin
A acetaminophen
C phenothiazine
B cholestyramine
D benzodiazepine
C d-Arg[Hyp3,Thi5,
D-Tic7,Oic8]bradykinin
B [Leu8]des-Arg9
-bradykinin
D DArg[Hyp3,DPhe7,
Leu8]bradykinin
3. Drugs that inhibit metabolism of Warfarin include all of the following except:
A amiodarone
C cimetidine
B disulfiram
D aspirin
C febuxostat
B allopurinol
D probenecid
C cefaclor
B cefepime
D cefadroxil
C mercaptopurine
B azathioprine
D infliximab
-1-
Pharmacology
8. Uricosuric drugs are
A organic acids acting at cation
transport sites of renal tubules
D decreases IL-10
C Tacrolimus
B Chenodeoxycholic acid
D Macrokine
pyrazolones
A. phenylbutazone
orange discoloration of urine
B. pyrazinamide
nicotinamide
C. oxaprozin
niacinamide
D. rifampin
propionic acid derivative NSAID E. energy metabolism
C losartan
B metamizol
D fenofibrate
C fluoride
B loop diuretics
D -agonists
C methothrexate
B cyclosporin
D azathioprine
-2-
Pharmacology
15. Match the following on the left with their correct options on the right:
A.
B.
C.
D.
E.
Glycopeptide anitibiotic
Polyene antibiotic
3rd Generation Cephalosporin
2nd Generation Cephalosporin
Quinolone antibiotic
A.
B.
C.
D.
E.
Cefotaxime
Nalidixic acid
Vancomycin
Cefuroxime
Amphotericin-B
C hyperkalemia
B hypokalemia
D hypernatremia
C digitalis glycoside
B -agonists
D spironolactone
18. Factors that increase drug metabolism includes all of the following except
A administration of Phenobarbital
C heavy smoking
B charcoal-boiled foods
19. Which Leukotriene is a potent chemo attractant for eosinophils and T lymphocytes?
A Leukotriene C4
C Leukotriene D4
B Leukotriene B4
20. Drugs that are absorbed intact from the small intestine include all of the following
except
A pentazocine
C meperidine
B morphine
D clonazepam
C aromatase enzyme
B 5a-reductase
D xanthine oxidase
-3-
Pharmacology
23. Match the following with their correct alternatives:
A.
B.
C.
D.
E.
Hepatolenticular degeneration
Cysteinyl LT1 receptor antagonist
Diabetes insipidus
-lactams
Aminoglycosides
A.
B.
C.
D.
E.
Carbapenems
Desmopressin
Penicillamine
Gentamicin
Montelukast
C IL-1
B IL-1a
D Leukotriene C4
C Ezetimibe
B Gemfibrozil
D Flurbiprofen
C Leflunomide
B Lenalidomide
D Tolazamide
C lisinopril
B fosinopril
D enalapril
28. Drug which should not be used for analgesia in patients with gout
A indomethacin
C oxaprozin
B aspirin
D glucocorticoid
C metformin
B thiazides
D diazoxide
C suppress hepatic
gluconeogenesis
-4-
Pharmacology
31. Mechanism of action and indications not common to both diazoxide and
sulfonylureas
A both cause membrane
depolarization
D used in coagulopathy in
Hemophilia B
C postural hypotension
34. Drugs that should not be suddenly withdrawn after prolonged treatment include all
of the following except:
A -adrenergic blockers
C procyclidine
B clozapine
D fluoxetine
cyclophosphamide
nafcillin
ondansetron
A. neutropenia
B. torsades de pointes
C. acute myeloid leukemia
D.
E.
ampicillin
cisplatin
D. nephrotoxicity
E. pseudomembranous colitis
C methotrexate
B cyclophosphamide
D Glatiramer
37. Match the following classes of interferons & interleukins with their correct sources:
A.
B.
C.
D.
E.
IFN-
IFN-
IFN-
interleukin-2
interleukin -3
A.
B.
C.
D.
E.
-5-
mast cells
lectin or antigen stimulated T cells
white cells
fibroblasts
lymphocytes
Pharmacology
38. What is not true regarding the actions of clonidine?
A has no effect on cardiac output
C propanolol
B guanethidine
D prazosin
C amphotericin B
B chloramphenicol
D gentamicin
C ethosuximide
B nicorandil
D cisplatin
C Fluoxetin
B Bedaquiline
D Amiodarone
Doxycycline
Salbutamol
Digoxin
Morphine
chlorpropamide
A.
B.
C.
D.
E.
1.6 hrs
32 hrs
40 hrs
2-3 hrs
20 hrs
C chlorthiazide
B amitriptyline
D clomethiazole
C Amiloride
B Quinidine
D Nifedipine
-6-
Pharmacology
46. Mechanism of action of amiloride
A antagonize the effect of
aldosterone in collecting tubules
C zolpidem
B Lithium
D carbamazepine
C eszopiclone
B zaleplon
D ziprasidone
C -hydroxy metabolites
B desmomethyldiazepam
D demoxepam
C propylthiouracil
B methimazole
D amiodarone
-7-