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operative/non-operative (medical)
diabetic/non-diabetic
trauma/non-trauma
severe sepsis
systemic steroid treatment
APACHE II 25 or <25.
Blood glucose management in both control and
experimental groups was guided by a specific web-based
treatment algorithm. Blood glucose samples were obtained
from arterial or central venous lines. Blood glucose
measurements were performed initially hourly, then reduced to
two- and then four-hourly once insulin infusion, blood glucose
concentrations and caloric intake were stable.
The intervention continued until the patient no longer
required supplementary enteral or parental nutrition and had
started eating, or until ICU discharge or death or completion of
the 90-day trial period.
Time to outcome
CER
EER
RRR
ARR
NNT
90 days
0.249
0.275
-10%
-0.026
-38
-19% to -2%
-0.048 to -0.004
-262 to -21
Key CER: control event rate EER: experimental event rate RRR: relative risk reduction ARR: absolute risk reduction NNT: number needed to treat
216
CAT reviews
Time to outcome
CER
EER
RRR
ARR
NNT
90 days
0.005
0.068
-1260%
-0.063
-16
-1447% to -1073%
-0.072 to -0.054
-19 to -14
Key CER: control event rate EER: experimental event rate RRR: relative risk reduction ARR: absolute risk reduction NNT: number needed to treat
217