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References:
Case-based
discussion,
Probst,
Cor
2011
and
2012
(times
new
Roman),
past-E.
The
pharynx
is
a
tubular,
fibromuscular
space
extending
from
the
skull
base
to
the
inlet
of
the
esophagus(upper
esophageal
sphincter)
The
pharynx
consists
of
a
nasal
part
(nasopharynx),
an
oral
part
(oropharynx),
and
a
laryngeal
part(hypopharynx).
The
primary
function
of
the
pharynx
is
to
coordinate
the
act
of
swallowing.
pharynx
also
contains
the
tonsillar
ring
that
is
important
in
the
immune
response
to
infection
Function
as
a
variable
resonance
chamber
for
modulating
vocal
sounds.
Nasopharynx:
This
highest
part
of
the
pharynx
extends
from
the
bony
skull
base
to
an
imaginary
horizontal
line
at
the
level
of
the
velum
The
nasopharynx
is
bounded
superiorly
by
the
floor
of
the
sphenoid
sinus
and
pharyngeal
roof.
Also
in
this
region
is
the
pharyngeal
tonsil
Medial
to
the
Eustachian
tube
orifice,
the
tubal
cartilage
forms
a
projecting
lip
called
the
torus
tubarius.
The
concavity
behind
it
is
termed
the
pharyngeal
recess
(Rosenmuller
fossa)
3
constrictor
muscles
of
the
pharynx:
Superior
Constrictor
muscle
-
The
elevation
and
contraction
of
the
velum
results
in
the
complete
closure
of
the
velopharyngeal
port,
this
action
is
facilitated
by
the
contraction
of
the
space,
which
narrow
the
pharynx.
Middle
constrictor
muscle
&
Inferior
constrictor
muscle
-
Initiation
of
pharyngeal
peristalsis
occurs.
The
bolus
is
carried
by
sequential
peristaltic
action
of
the
middle
and
inferior
pharyngeal
constrictors
into
and
through
the
pharynx
to
the
cricopharygneal
sphincter.
all
3
are
responsible
for
the
pharyngeal
phase
of
swallowing
Three
muscular
weak
points
exist
in
the
lower
posterior
wall
of
the
hypopharynx.
The
first
is
the
Killian
triangle,
located
between
the
constrictor
pharyngis
inferior
and
the
uppermost
fibers
of
the
cricopharyngeus
muscle.
o common
site
for
the
formation
of
hypopharyngeal
diverticula.
The
second
area
of
weakness
is
the
KillianJamieson
region
between
the
oblique
and
transverse
fibers
of
the
constrictor
pharyngis.
The
third
is
the
Laimer
triangle,
which
is
bounded
above
by
the
cricopharyngeus
and
below
by
the
uppermost
fibers
of
the
esophageal
musculature
II.
ADULT
SWALLOW
PHYSIOLOGY
PAST
TRANX:
1. Complete closure of velopharyngeal opening
If the soft palette does not close, the food contents go to the nose.
2. Hyoid & larynx begin their superior ascent
Hyoid and larynx are elevated because of suprahyoid muscles that pulls the hyoid which
suspend the larynx up, to meet the epiglottis)
3. Epiglottis begins to downfold
epiglottis is a stationary object at the base of the tongue so it doesnt really go down but the
edges are the one that close because the muscles pull the edges downward. Epiglottis seals
the larynx from entry of food or liquid)
4. Tongue base to posterior pharyngeal wall contact
tongue pushes the epiglottis further down)
5. Top to bottom contraction of constrictors (stripping motion)
6. Continued superior movement of hyoid & larynx
7.
8.
9.
10.
C. Esophageal Phase
Primary
peristalsis
Relaxation
and
opening
of
the
lower
esophageal
sphincter
Secondary
peristalsis
III.
Cases
A.
CASE
1
A
24
year
old
call
center
agent
with
recurrent
sore
throat
and
fever
consulted
you
for
increased
snoring
and
sensation
of
throat
pain
when
swallowing.
He
has
been
feeling
weak
lately
and
fatigues
easily
after
scaling
just
one
flight
of
stairs.
He
has
a
five
year
history
of
purulent
nasal
discharge,
ear
pain
and
dry
cough.
As
a
child
he
has
had
3
to
4
episodes
of
sore
throat
per
year
for
which
he
was
given
antibiotics
by
his
pediatrician.
He
has
been
smoking
one
pack
of
cigarettes
per
day
on
and
off
for
the
past
twenty
years
(he
quitted
smoking
twice)
and
drinks
alcohol
with
his
colleagues
once
or
twice
a
week
after
work.
He
hits
the
gym
once
a
week,
lifting
heavy
weights,
until
he
had
a
rotator
cuff
injury.
He
denies
taking
anabolic
steroids
but
takes
Extra
Joss
and
Red
Bull
before
and
after
workouts.
Despite
this,
he
has
been
steadily
gaining
weight
for
the
past
year.
His
waist:hip
ratio
is
1.2.
He
has
been
taking
Klaricid
OD
for
the
past
3
days
and
asks
you
if
he
needs
to
continue
it.
He
also
wants
to
know
if
he
can
have
his
tonsils
removed
because
he
would
often
get
sore
throat
after
even
just
a
mug
of
iced
mochacinno
at
Starbucks
(he
sticks
to
a
cup
of
espresso
with
every
meal).
Ask if patient is currently taking any medications and his past medications
Sudden onset is consistent with a GAS pharyngitis. Pharyngitis following several days of
coughing or rhinorrhea is more consistent with a viral etiology.
Recent exposure to someone with strep throat or any other infection of the throat, nose, or ears
Ask if patient has headache, cough or vomiting
A complete and thorough physical examination should be done. There should be some
focus on the inspection of the throat due to its recurrent soreness.
Otoscopy should be done in order to assess ear problems and inspection of the nasal
cavity should also be included to determine the cause of the discharge.
Due to the patients smoking history and current complaint of easy fatigability, a
complete physical examination of the chest and lungs should be done in order to assess
his heart and lungs.
3.
List
the
likely/possible
clinical
diagnosis
in
this
patient
and
give
the
bases
for
each.
VVascular
Leukemia patient should present with unilateral enlargement of the tonsils. Symptoms of leukemia
include: fever, unexplained weight loss, general discomfort, sore throat, swollen gums, drenching night
sweats, headache, vomiting, vision problems, bone or joint pain and painless swelling of the lymph nodes.
IInflammatory
Streptococcal pharyngitis
Viral pharyngitis
Herpangina (due to Coxsackie virus)
Pharyngoconjunctival fever (due to eight or more viruses)
Infectious mononucleosis
Viral influenza may begin with a sore throat
Tuberculosis
NNeoplasm and carcinomas may include Hodgkin disease and leukemia.
DDegenerative diseases are an unlikely cause of sore throat.
IIntoxication
May include chronic alcoholism and smokers throat
CCongenital diseases are an infrequent cause of sore throat
Hiatal hernia with reflux esophagitis may cause recurrent sore throat, because there may be reflux
of gastric juice all the way to the posterior pharynx in the recumbent position.
An elongated uvula may also be responsible.
AAllergic diseases
Angioneurotic edema of the pharynx or uvula and allergic rhinitis
TTrauma
Foreign bodies such as chicken bones and tonsilloliths
EEndocrine
Subacute thyroiditis - although the pain is really in the neck, the patient will report a sore throat.
4.
Are
there
additional
diagnostic
examinations
needed?
What
are
these
and
give
your
bases
for
each?
a. Throat culture
the use of a throat culture plated on sheep blood agar to confirm the presence of GAS has been a
common office practice.
The optimal site for throat culture is the surface of the posterior pharynx
These tests all are based upon detection of the carbohydrate antigen of GAS with an antibody
tagged reagent which produces a clumping effect or color change after the antigen-antibody
interaction.
When the rapid GAS antigen test is positive, the result can be deemed reliable and the patient
treated appropriately. In contrast, when rapid antigen detection testing produces a negative result,
the use of a second swab for confirmatory culture should be considered to avoid missing a
positive infection, particularly if there is a high clinical suspicion of GAS or rheumatogenic
strains are circulating in the community.
Streptococcal antibodies antibodies to GAS (antistreptolysin O) do not peak until four to five
weeks after the onset of pharyngitis. Thus, measurement of streptococcal antibodies is useful only
for the retrospective diagnosis of infection
Blood teststo identify conditions that may be causing the sore throat
Mono spot test (if mononucleosis is suspected)
5.
What
are
the
management
options
for
this
patient
and
the
likely
benefits/risks
for
each?
a)
Discuss
the
basis
for
giving
antibiotics
to
this
patient.
Do
you
agree
with
the
current
antibiotic
therapy
of
this
patient?
Antibiotics are usually prescribed if the patient presents with signs and symptoms that support a
bacterial etiology, such as fever or the presence of exudates.
Antibiotic use also reduces the incidence of acute otitis media and acute sinusitis, which may be
present in the patient given his history of ear pain and nasal discharge. T
the patient was given Clarithromycin (Klaricid), a macrolide indicated for infections of the lower
respiratory tract, skin and soft tissues.
b) Discuss the basis for tonsillectomy in this patient. Would you advise tonsillectomy to this patient?
c)
What
other
interventions
would
you
consider
in
this
patient
and
provide
the
bases
for
each?
Adenoidectomy
-
Because
adenoid
tissue
has
similar
bacteriology
to
the
pharyngeal
tonsils
and
minimal
additional
morbidity
occurs
with
adenoidectomy
if
tonsillectomy
is
already
being
performed.
2.
TB
-
TB
culture
-
PCR
can
also
detect
TB
3.
HIV/AIDS
-
HIV
has
increased
prevalence
among
call
center
agents,
thus
elicit
sexual
history.
-
on
PE,
also
do
tests
for
HIV.
Management
Issues
-Antibiotics
(Clindamycin,
Amoxicillin/Clavulanic
acid)
-antibiotics
are
effective,
they
eliminate
the
symptoms
if
the
cause
is
bacterial
and
reduce
the
risk
of
glomerulonephritis
and
fever
-
however,
take
note
of
side
effects:
Clindamycin:
abdominal
pain,
necrotizing
enterocolitis
Amoxcillin:
diarrhea,
dehydration
and
electrolyte
imbalance
-determine
antibiotic
resistance
-
start
1st
with
penicillin/erythromycin/Co-trimoxazole.
Penicillin
is
the
DOC
for
Acute
tonsillitis
For
Bacterial
Tonsillopharyngitis:
Random
Egyptian
Fact
2:
Dx:
no
throat
swab
-
do
rapid
strep
immunoassay
The
story
of
Cinderella
started
in
Ancient
Egypt,
with
Rhodopis
as
Tx:
oral
penicillin
G
(400-800
k
units)-
4x
a
day
for
10
days
the
name
of
Cinderella.
It
involved
For
children:
(25-90k
units)-
10-14
days
jealous
servants,
a
lost
slipper
and
IV
Penicillin
G
(
5-
30
Million
units/kg/day)
a
happy
ending
w/
Pharaoh.
Children:
(
100-250
K
units/kg/day)
-
hydration
and
antipyretics
Note:
Not
all
chronic
tonsillitis
is
an
infection
*
NOT
ALL
CONDITIONS
ARE
VIRAL
OR
INFECTION
ALWAYS!
-
Postnasal
drip
conditions
are
not
resolved
by
antibiotics
Characterized
by:
Posterior
pharyngeal
discharge
Hypertrophied
lymphoid
follicles
Chronic
throat
clearing/
pruritus
Dry
cough
Vague
throat
discomfort
Allergic
Sx
-
Practice
Antibiotic
Stewardship
To
prevent
reisitance
Rotate
antibiotics.
Example
Co-trimoxzole
resistance
in
hospital
is
at
70%,
so
give
other
drugs
Surgeries:
1.
Tonsillectomy
Being
Lymphoid
Tissue,
the
Tonsils
are
expected
to
inflame
DIFFUSELY,
BILATERALLY,
but
NOT
necessarily
symmetrically
-
recurrent
pharyngitis
can
recur
after
tonsillectomy
-
be
careful
on
advising
it.
The
tonsillectomy
dilemma:
Attack
rate
of
ARF
in
untreated
culture
+
children
=
0.3-0.9%
Attack
rate
of
RF
in
adults
=
3%
Attack
rate
of
AGN
=
10-15%,
0
recurrence
There
is
no
evidence
from
randomised
controlled
trials
to
guide
the
clinician
in
formulating
the
indications
for
surgery
in
adults
or
children.
Indications
for
tonsillectomy:
Severe
obstruction
to
swallowing
and/or
breathing
due
to
enlarged
tonsils-AN
INDICATION
Other
so-called
relative
indications
have
no
clear
benefit
and
can
even
be
harmful
Recurrent,
medically
intractable
middle
ear
effusion
with
hearing
loss
Common
Causes
of
UNILATERAL
Tonsillar
enlargement
Peritonsillar
Abscess
(Quinsy
Throat)-
Complication
includes
retropharyngeal
abscess
Occurs
in
between
tonsillar
fascia
and
superior
constrictor
Hot
potato
voice
Primary
Tonsillar
Carcinoma
Metastatic
cancer
from
a
distant
site
Lymphoma
Ominous
Signs
in
UNILATERAL
Tonsillar
enlargement
Weight
loss
Halitosis
Massive
/
Rapid
Enlargement
Painless
Enlargement
Cranial
Nerve
Involvement
Lymph
Node
Involvement
/
Hepatosplenomegaly
2.
Adenoidectomy
-
tonsillitis
is
NOT
equal
to
adenoiditis
-
it
does
not
have
same
risks.
-
may
cause
hyponasal
speech,
chronic
rhinitis,
sinusitis,
and
otitis
media
due
to
obstructed
Eustachian
tube
opening
-
bilateral
otitis
media
with
effusion
may
cause
hearing
loss.-
AN
INDICATION
FOR
IT.
Other
interventions:
Lifestyle
modifications-
diet
PPI,
(20-40
mg
before
breakfast)
Antacids
such
as
Mg
and
Al
OH
H2
blockers
B.
CASE
2
A
2
year
old
boy
was
brought
by
his
parents
for
recurrent
cough,
fever
and
poor
appetite
since
one
month
ago.
His
cough
sounds
like
a
barking
seal.
He
also
has
been
having
recurrent
right
ear
pain.
On
physical
examination
he
has
low
grade
fever,
alar
flaring
and
enlarged
tonsils.
You
also
note
mild
chest
retractions.
He
is
irritable
and
appears
to
be
hungry.
You
offer
him
some
juice.
He
takes
some
but
refuses
to
finish
the
rest.
He
refuses
to
lie
down
and
prefers
to
sit
hunched
forward
with
his
arms
propping
him
up.
He
points
to
the
toys
you
keep
in
your
clinic
and
selects
your
Lego
construction
set.
His
mother
says
those
are
his
favorite
toys
but
he
tends
to
put
them
in
his
mouth
so
she
took
them
away.
a.
Answers
to
Case
2
(Cor
2012)
Perform a Mirror Exam - assess if both tonsils are swollen, bright red and coated.
Palpate the lymph nodes on along the jaw and on the neck, assess if they are swollen and tender.
Examine the nose to check for inflammations, infections and post nasal conditions.
Perform an otoscopic examination of the ear to check for any inflammations.
In the physical examination, it is important to know if there is fever and if there are signs of
respiratory distress such as tachypnea, dyspnea, stridor and tripod positioning which are present
in this case.
Tripod position consists of sitting upright, leaning forward with neck hyperextended and jaw
thrust forward.
Tonsillitis it can be due to viral or bacterial infection. The common symptoms include enlarged
tonsils, cough and fever
Tonsillopharyngitis its symptoms include cough, low grade fever, poor apetite, and enlarged
tonsils
Epiglottitis symptoms include fever, cough and irritability
Infectious mononucleosis it is a mild upper airway obstruction that presents as an intermittent
alar nasal flaring and stridor in supine position. It is common in children less than four years old.
Aspiration it is the inhalation of foreign objects into the airway. It is common in infants and
toddlers.
4.
Are
there
additional
diagnostic
examinations
needed?
What
are
these
and
give
your
bases
for
each?
Swab culture of throat specimen could confirm the etiologic agent present
Serologic tests can confirm presence of infectious mononucleosis
Fine needle aspiration evaluates microflora in chronic tonsillitis
X-ray can determine presence of aspirated objects
Flexible laryngoscopy can assess the size of the tonsil
5.
What
are
the
management
options
for
this
patient
and
the
likely
benefits/risks
for
each?
Tonsillitis pain management, medications, lozenges, gargling solution of warm water and salt
Epiglottitis tracheal intubation to protect the airway and antibiotics (3rd generation
cephalosporins)
Infectious mononucleosis no specific treatment is necessary because it is self-limiting.
Treatment is directed towards relief of symptoms. Supportive measures are necessary.
b.
Discussion
(Dr.
Acuin)
-
note
the
patients
position.
If
a
patient
is
leaning
forward,
the
tongue
hangs
out,
but
if
leaning
back,
it
falls
back.
-
assess
the
adequacy
of
airway
-
in
swollen
epiglottis,
tell
the
patient
to
open
mouth
and
say
ahh,
use
a
mirror
to
reflect
the
uvula.
This
is
known
as
indirect
larnyngoscopy
-
Laryngeal
spasm
is
dangerous
because
of
no
breathing
-
Do
a
flexible
laryngoscopy
to
the
pharynx
-
Do
an
X-ray
of
the
neck
for
epiglotittis.-
common
among
4-6
year
olds.
-
Note
the
barking
cough
of
the
patient,
this
may
signify
croup.
-
Note
the
dysphagia
A
large
foreign
body
may
obstruct
the
esophagus-
true
emergency
May
not
obstruct
airway
In
the
brobchopulmoanry
segment,
it
may
cause
atelectasis
and
recurrent
pneumonia
Look
for
draining
sinuses
and
do
X-ray
c.
Assessment
of
Foreign
Body
Break
Quote:
Question by a Student:
If a single teacher can't teach us all the subjects,
then how could you expect a single to student to learn all the subjects?
C.
Case
III
A
65
year
old
female
is
recovering
from
her
stroke.
Currently
she
is
being
fed
through
a
nasogastric
tube
but
her
attending
physician
is
referring
her
to
you,
the
ENT
physician,
to
determine
if
she
can
be
safely
fed
through
her
mouth.
a.
answers
1.
Describe
the
mechanisms
by
which
stroke
can
lead
to
swallowing
disorders.
Cerebral lesions can interrupt voluntary control of mastication and bolus transport during the oral
phase.
Cortical lesions involving the precentral gyrus may produce contralateral impairment in facial,
lip, and tongue motor control, and contralateral compromise in pharyngeal peristalsis.
Brain stem strokes are less common than cortical lesions but result in the largest swallowing
compromise. Brain stem lesions can affect sensation of the mouth, tongue, and cheek, timing in
the trigger of the pharyngeal swallow, laryngeal elevation, glottic closure, and cricopharyngeal
relaxation.
In people with neurological problems, it is easier for them to swallow solid because liquids
demand greater coordination
In stroke patients who might have problem in swallowing water, liquids are thickened to have a
more solid consistency, allowing for better control by the weakened musculature involved in
swallowing
2.
What
signs
and
symptoms
would
you
ask
for
to
determine
if
she
is
a
safe
oral
feeder?
presence
of
dysphagia.
This
increases
the
risk
for
aspiration
pneumonia
if
the
patient
is
not
able
to
swallow
well.
A
swallowing
test
may
be
performed
to
determine
this.
If
a
patient
is
able
to
swallow
down
small
amounts
of
food
or
liquid,
then
it
is
probably
safe
to
start
oral
feeding,
although
slowly.
. A psychiatric consult may be needed to assess a patient before oral feeding is instituted.
*Definition of safe oral feeder- only 1 attempt to swallow liquid and solids foods (with no residual fluid left)
3.
How
would
you
physically
assess
the
different
phases
of
her
swallowing
function?
Oral phase
If there is a problem
during this phase, the
patient may find it
difficult to chew solids
and to contain the liquid
in the oral cavity before
swallowing. She may
also have a hard time to
initiate swallowing.
Pharyngeal phase
After swallowing, the
patient
may
retain
excessive amounts of food
in the pharynx if there is
weakness in or lack of
coordination
of
the
pharyngeal muscles or if
there is a poor opening of
the
upper
esophageal
sphincter.
Esophageal phase
After swallowing, the patient
may retain food and liquid in
the esophagus after swallowing
if there is a mechanical
obstruction, a motility disorder,
or an impairment of the
opening
of
the
lower
esophageal sphincter.
Trouble swallowing saliva but
no difficulty swallowing food
globus hystericus
4.
What
diagnostic
examinations
can
be
performed
to
further
evaluate
her
swallowing
function?
Barium Swallow Exam - Modified
Cervical Auscultation
Double Contrast Barium Enema
Double Contrast Upper GI
Electrogastrography
Spectral Analysis on EMG
Endoscopy
Fiberoptic Endoscopic Examination of Swallowing
FEEST - Flexible Endoscopic Evaluation of Swallowing with Sensory Testing
Gastroscopy
Manometry
pH probe
Ultrasound
Upper GI for GERD
5.
What
interventions
can
be
done
to
help
her
swallow
safely?
Rehabilitation therapy is the main stay of dysphagia management and allows for safe swallowing
Oral feeding with consistency modification thickened liquids increase oropharyngeal control,
while a diet of shopped or pureed foods decreases difficulties with mastication. It consists of 8
varieties of diet.
Compensatory strategies to reduce the risk of aspiration
Chin tuck decrease air diameter
Head rotation ipsilateral pharynx is closed forcing bolus to contralateral pharynx
Head tilt guide bolus to ipsilateral pharynx
Supraglottic swallow simultaneous swallowing and breath holding, closing vocal cords
Mendeleon maneuver form of supraglottic swallow in which the patient mimics the
upward movement of larynx by voluntary holding of larynx
Exercise and facilitation techniques
Exercise is used to increase muscle tone and alignment pharyngeal swallow
Biofeedback techniques are used to reeducate muscle affected in facial palsy and
disorders of articulation
Thermal stimulations in the form of icing of the anterior facial muscles can be performed
to help decrease delay of pharyngeal swallow
Medical interventions Diltiazem aid in esophageal contractions and motility
Endoscopic and surgical interventions
Microsurgical techniques to help in swallowing
Laryngectomy or laryngotracheal diversion
Tracheostomy is often performed as a permanent palliative measure when all else fails
Non-oral feedings
Parenteral alimentation and IV fluid replacement
Nasogastric tubes are convenient for short term but has many complications
jejunostomy
b.
Discussion
(Dr.
Acuin)
How
to
determine
if
patient
is
a
safe
oral
feeder?
S/Sx-
listen
to
patients
voice-
if
gurgly
or
bubbly=
cannot
swallow
-
swallows
spit
and
aspirates
-
afferent
arm
of
reflex
not
activated
-
note
that
swallowing
reflex
in
pharynx
and
larynx
is
involuntary
Dx.
Exam
barium
swallow-
trace
the
pathway
of
swallowing
but
subject
to
radiation
flexible
eval.
Of
swallowing-
valecula,
pyriform
sinus,
vocal
fold
at
risk
of
aspiration
o done
at
bedside,
no
radiation
o does
not
directly
evaluate
strength
of
swallow.
Assessing
the
Possible
Problem
Site
:
Oropharynx
Pharyngotonsilitis
Random
Egyptian
fact
3:
Vincents
angina
Inf.
mononucleosis
Cleopatra
VII
was
the
last
ruler
of
Diphtheria
ancient
Egypt.
Her
beauty
and
charm
TB
won
the
love
of
an
emperor
and
a
Aphthous
ulcers
Fungal
pharyngitis
soldier.
Neoplasm
Hypopharynx
Epiglotitis
Supraglotitis
Valleculitis
Neoplasm
Larynx
Laryngitis
-
involved
vocal
folds
itself,
may
have
referred
pain
Neoplasm
Esophagus
Cervical
Esophagitis
referred
pain
Neoplasm
Cervical
Fascia
Lymphadenitis
Thyroiditis
Neoplasm
Deep
neck
fascitis
Cellulitis
DIFFERENTIALS
Non-infectious
Inflammation
Allergy
/
Hypersensitivity
Chemical
/
irritative
Systemic Diseases
HIV
Leukemia
Lymphoma
Tuberculosis
Connective
Tissue
Disease
Neoplasm
Benign
Primary
Malignancy
Metastatic
Cancer
Velopharyngeal
competence
o The
velopharynx
a
particularly
narrow
segment
of
the
upper
airway,
is
especially
predisposed
to
obstruction
in
such
settings.
o
In
particular,
obese
patients
with
large
necks
often
have
a
more
collapsible
velopharynx
that
predisposes
to
upper
airway
obstruction.
o In
many
patients
with
OSA
collapse
of
the
velopharynx
can
be
induced
by
having
the
patient
perform
Muller's
manoeuvre
during
nasopharyngoscopy
o In
Muller's
manoeuvre
the
patient
is
asked
to
take
a
breath
while
the
mouth
is
closed
and
the
nose
is
pinched
shut.
o This
generates
a
negative
pressure
in
the
upper
airway.
In
patients
who
just
snore,
there
may
be
slight
inward
movement
of
the
soft
palate
and
the
back
of
the
throat
but
the
glottis
remains
visible.
o
Patients
who
have
OSA
show
varying
degrees
of
collapse
in
the
side
walls
of
the
velopharynx,
at
the
base
of
the
tongue,
and
at
the
back
of
the
throat,
which
narrows
the
airway
by
more
than
25%.
o Patients
with
the
degree
of
collapse
seen
here
usually
have
moderately
severe
OSA
or
worse.
Sleep
apnea
treatments
o Modify
sleep
position?
o Weight
reduction?
o Respiratory
stimulants
tricyclic
antidepressants,
L-tryptophan,
etc?
o CPAP?
o Oral
appliances?
o Surgery
(nose,
throat,
oral
cavity,
face)?
-------------------------------------------------------END
OF
TRANSWINTION--------------------------------------------------
Akala
ko
madugo
gumawa
ng
tranx
ng
ophtha,
meron
plang
mas
basag
na
lecture.
Ang
ENT,
bow.
Sorry
kung
magulo
format.
Medyo
maraming
refs
din
ang
ginamit
ko
dito,
3
years
worth
of
knowledgehehe.
Baka
huli
ko
na
to.
Nakakatamad
nang
gumawa.
Hehe.
Pabati!
Hi
sa
mga
bumili
ng
tickets
sa
akin:
Si
Jela
(unang
biktima),
Owis,
JC,
Mariel,
juxy,
Gabriela(
este
Jen
pala
),
Yeji,
Gelli,
Betty,
HAC,
Franz,
Bei,
Carine,
Ana,
Bern,
Menchai,
Kathee,
Nepo,
Lyreen,
Nicole
O,
Kat
Y.,
Maika
at
finaleHomer!
Good
luck
guys!
Hope
to
see
you
din
sa
Scholaroyale
2012.
Kudos
din
to
all
the
subject
heads
and
editors
for
this
set
of
tranx.
Just
2
rounds
of
evals
and
1
set
of
finals,
and
we
will
now
be
called
Junior
interns.
The
underworld
would
be
a
very
lonely
place
without
you,
my
goddess
of
light
RANDOM
EGYPTIAN
FACT
4:
The
story
of
Isis
and
Osiris
is
the
greatest
love
story
of
ancient
Egypt.
The
jealous
Seth,
God
of
the
desert,
cut
Osiris
into
14
pieces
across
Egypt.
But
Isis
searched
for
all
pieces
for
many
years,
and
with
after
completing
the
parts,
used
love
to
bring
him
back
to
life
for
a
final
embrace.