Академический Документы
Профессиональный Документы
Культура Документы
Choukroun PRF, et al. in 2001 in France, it contains 97% platelet and 50% leukocyte
(Malathi et al., 2013). The PRF contains a dense fibrin network with leukocytes,
cytokines, growth factors and glycoproteins such as transforming growth factor 1.
Platelet-derived growth factor, vascular endothelial growth factor and
thrombospondin-1 glycoprotein like PRF leukocytes play a role in the release of
growth factors, immune regulation, anti-infective activity, and matrix remodeling
during wound healing.
Platelets (thrombocytes) are a key element in wound healing, therefore wound
healing after periodontal treatment can be accelerated by using PRF (Chandran and
Sivadas, 2013). Wound healing process starts from the formation of blood clots and
tissue injury in the event of post-surgical periodontal cause platelet incorporation
supported by the formation of thrombin and fibrin.
PRF can improve the healing of both soft tissue and hard tissue in periodontal
treatment, therefore PRF is a powerful healing biomaterials with high regenerative
capacity and can be used in a variety of procedures such as periodontal defects in the
form of intrabony defects, furcation treatment, removal of sinus and useful as media
in vitro studies in tissue engineering.
PRF was obtained from the patient's own blood by means of blood sampling on
the antecubital vein. The blood was then placed into a sterile 10ml tubes without
anticoagulant and was then centrifuged using centrifuge machine.
(a)
(b)
(c)
(d)
Indications:
(a) Vertical/angular 3-walled bone defect.
(b) Vertical/angular 2-walled bone defect bone defect; provided the defect is not too
wide.
Bone-grafting procedure:
(a) Anesthesia
(b)
(c)
(d)
(e)
(f)
(g)
(h)
(i)
Bone-grafting illustration: (Top left) bone graft material is placed in the bone defect and prepared
root surface area. (Top right) flap is closed and stitched. (Bottom) bone graft material has been
fused with the healthy tissue of the alveolar bone