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FUNCTIONAL FOOD
by
I. PENDAHULUAN
Terminologi Awal Functional Food
- Semua makanan adalah fungsional memberi rasa, aroma, dan
nilai gizi (Silalahi, 2001).
- Istilah fungsional terkait dengan efek fisiologis yang
menguntungkan, selain sumber gizi.
- Banyak komponen minor non nutritif dalam makanan mencegah
dan mengobati penyakit
Makanan Fungsional
FUNCTIONAL FOOD
Health Food Designer Food Pharmafood Vitafood - Netraceutical
Functional Food
1. Mengandung komponen (zat gizi/non gizi) yang berfungsi positip bagi tubuh.
2. Mengandung bahan-bahan yang dapat meningkatkan status kesehatan.
3. Mengandung bahan-bahan yang dapat mencegah timbulnya penyakit-penyakit
tertentu.
Pangan
Fungsi Primer = mempunyai komposisi gizi yang baik
Fungsi Sekunder = mempunyai penampakan dan citarasa yang menarik
Fungsi Tersier = mempunyai fungsi fisiologis bagi tubuh
Functional
Foods
Ingredients:
Functional
Food
Ingredients
Vegeta
Yoghurt, Kefir, Coumiss
Yakult
Breakfast cereals
Biscuit
Minuman
Permen
+
Lactobacillus bulgaricus
+
Streptococcus thermophilus
Bifidobacterium animalis
DN-173 010
+
Lactobacillus bulgaricus
+
Streptococcus thermophilus
PROBIOTIK
Sekumpulan mikroba yang memberikan efek ++ bagi kesehatan
mikroba secara alami ada pada saluran pencernaan
mikroba ditambahkan berupa bahan tambahan pangan
mikroflora produsen asam laktat bakteri asam laktat
Lactobacilli dan Bifidobacteria
Bakteri ini dikonsumsi dalam keadaan hidup
Mampu bertahan hidup dalam saluran pencernaan
Elie Metchnikoff (1908)
- Konsumsi susu fermentasi dengan Lactobacilli akan
memperpanjang hidup manusia
Kidneys: sterile
Bladder: sterile
Urethra: 101-102 E. coli
Digestion
Production of vitamins
Mucosal maturation
Stimulate Immune System
Attachment
Intestinal transit
Colonization resistance
Welcome to your
microbial life!
Bacteria
SKIN
ESOPHAGUS
COLON
STOMACH
Bacteroidetes
VAGINA
Firmicutes
Gut Flora in
Breast Fed vs Formula Fed Babies
29
Friendly bacteria
Unfriendly / harmful Bacteria
Probiotics
Pathogens
Common flora
Facultative Anaerobes
Staph. Aureus, albus
Strict anaerobes
Nose & skin
Candida albicans
E. Coli.
Haemophilus Sp.
Pseudomonas aeruginosa
31
Manfaat Probiotik
Perbaikan pencernaan laktosa
- adanya enzim laktase yang mampu memecah
laktosa
Pengurangan serum kolesterol
- adanya bile salt hydrolase menurunkan kolesterol
Penghambatan tumor
- senyawa dinding sel bakteri probiotik (peptidoglikan)
menyerap senyawa karsinogenik
Pencegahan konstipasi
- asam laktat merangsang gerak peristaltik usus
mencegah sembelit
Pencegahan terhadap diare akibat Helicobacter pylori
Manfaat Probiotik
Produksi bakteriosin
Pembentukan Vit. B
Peningkatan penyerapan kalsium mencegah
osteoporosis
Inaktivasi komponen toksik
Stimulasi sistim kekebalan tubuh
Kontrol patogen usus (Clostridium perfringen, E. coli,
Salmonella, Shigella, Listeria)
Bakteri Probiotik
Produk Probiotik
Bakteri Probiotik
Lactobacillus bulgaricus, L.
acidophilus, L. casei, L. reuteri,
Streptococcus thermophilus,
Leuconostoc mesenteroides,
Bifidobacteria
Lactobacillus bulgaricus, L.
acidophilus, L. reuteri,
Streptococcus thermophilus,
Bifidobacteria
Lactobacillus bulgaricus, L.
acidophilus, Bifidobacteria
L. acidophilus, Bifidobacteria
Probiotic strains
Lactobacillus species
L. acidophilus
L. plantarum
L. casei subspecies rhamnosus
L. brevis
L. delbreuckii subspecies bulgaricus
Bifidobacterium species
B. adolescentis
B. bifidum
B. longum
B. infantis
B. breve
Others
Streptococcus salivarius ssp. thermophilus
Lactococcus lactis ssp. lactis
Lactococcus lactis s ssp. cremoris
Enterococcus faecium
Leuconostoc mesenteroides ssp. dextranicum
Propionibacterium freudenreichii
Pediococcus acidilactici
Saccharomyces boulardii
1 billion/100 gm
B. Lactis and L.
acidophilus
1 billion/100 gm
B. lactis
(B. regularis)
10 billion/100 ml
1 billion/100 gm
L casei
B. Lactis and L.
acidophilus
15 billion
CFU
L. acidophilus, B. lactis
L. Bulgaricus, B. longum
L. rhamnosus, L. brevis,
S. thermophilus, L. casei, L. salivarius
L. lactis, B. breve, L. plantarum
L. paracasei, B. bifidum
1.5 billion
CFU
30 billion CFU
Lactobacillus gasseri (KS-13)
Bifidobacterium bifidum (G9-1)
Bifidobacterium longum (MM-2)
S. Thermophilus KB19
L. Acidophilus KB27
B. Longum KN31
Lactobacillus rhamnosus GG
Dietary Supplement: Culturelle
PREBIOTIK
Broste (1991)
- Konsep baru prebiotik berdasarkan adanya probiotik
Prebiotik
- Bahan tambahan makanan yang tidak dapat dicerna
- Bahan yang menguntungkan bagi tubuh dengan merangsang
pertumbuhan/aktifitas satu atau beberapa jenis bakteri dalam usus
secara selektif yang dapat memperbaiki kesehatan tubuh.
Sumber Prebiotik :
1. Human Milk Oligosaccaharides ASI Air Susu Ibu 130
GalOS 3000-6000 ppm
2. Sayur & buah : Bawang merah, asparagus, chicory, pisang,
artichoke.
Jenis Prebiotik
1. Galakto-oligosakarida (GalOS)
2. Frukto-oligosakarida (FOS)
3. Gluko-oligosakarida
4. Manno-oligosakarida
5. Inulin
6. Laktulosa
7. Laktitol
8. Xylosa
9. Mannosa
Produksi Prebiotik :
1. Ekstraksi langsung polisakarida alami dari tumbuhan
2. Hidrolisa polisakarida alami
3. Sintesa enzimatis dengan enzim hidrolase atau glikosil transferase
prebiotik sintetis
Prebiotik Sintetis :
Galakto-oligosakarida
Frukto-oligosakarida
Isomalto-oligosakarida
Gentio-oligosakarida
Xilo-oligosakarida
Laktulosa
Laktusukrosa
Prebiotik Kuat
prebiotics
Prebiotik
Usus
Asam asetat
Asam Propionat
Asam Butirat
Asam Laktat
Probiotik
Prebiotik
Sinbiotik
Kombinasi penggunaan mikroba hidup (probiotik) dan substrat pertumbuhan (prebiotik)
FOS + Bifidobacteria
Lactitol + Lactobacilli
Synbiotics
It is also possible to increase and maintain a healthy bacterial gut
flora by increasing the amounts of prebiotics in the diet such as
inulin, raw oats, and unrefined wheat.
As probiotics are mainly active in the small intestine and prebiotics
are only effective in the large intestine, the combination of the two
may give a synergistic effect.
Appropriate
synbiotics
combinations
of
pre-
and
probiotics
are
SERAT MAKANAN
DIETARY FIBER
Dietary Fiber
By chemical analysis fiber can be
broken into soluble and insoluble
components (resistant starch identified by other chemical method)
Soluble components are pectic substances, some hemicelluloses,
gums and mucilages and are completely fermented by the bacterial
flora
Insoluble components are cellulose, some hemicelluloses, waxes, and
lignin primarily in plant cell walls as well as resistant starch are only
slightly fermented
Wheat is 90% insoluble and 10% soluble
Oats are 50% insoluble and 50% soluble
Psyllium 10% insoluble and 90% soluble
Dietary Fiber
Physiologic Properties
1. Slows transit in small bowel
2. Increases stool bulk
3. Holds on to water
4. Forms gels
5. Binds minerals and organic substances
6. Stimulates bacterial growth
7. Metabolized to SCFA
Starch
Bacterial
+
Non-starch
Enzymes
Polysaccharides
Butyric (22)
Acetic (56)
Propionic(61)
FERMENTABLE FIBER
The American Association of Cereal Chemists : soluble fiber = the
edible parts of plants or similar carbohydrates resistant to digestion
and absorption in the human small intestine with complete or partial
fermentation in the large intestine.
edible parts of plants all parts of a plant we eat : skin, pulp, seeds, stems,
leaves, roots contain fiber. Both insoluble and soluble sources are in plant.
carbohydrates complex carbohydrates, such as long-chained sugars also
called starch, oligosaccharides or polysaccharides, are excellent sources of
fiber.
resistant to digestion and absorption in the human small intestine foods
nutrients are digested by gastric acid and digestive enzymes in the stomach
and small intestine where the nutrients are released then absorbed through the
intestinal wall for transport via the blood throughout the body. A food resistant to
this process is undigested, as insoluble and soluble fibers are. They pass to the
large intestine only affected by their absorption of water (insoluble fiber) or
dissolution in water (soluble fiber).
complete or partial fermentation in the large intestine additional nutrient
absorption occurs through the process of fermentation in colon. Fermentation
occurs by the action of colonic bacteria on the food mass, producing gases and
short-chain fatty acids.
SUMBER SERAT
The American Dietetic Association recommends consuming a variety of fiber-rich foods.
Soluble Fiber
Insoluble fiber
KANDUNGAN SERAT
(GR)
Alpukat
Anggur
Apel
Belimbing
Jambu Biji
Jeruk Bali
Jeruk Sitrun
Mangga
Melon
Nanas
Pepaya
Pisang
Semangka
Sirsak
Srikaya
1,4
1,7
0,7
0,9
5,6
0,4
2
0,4
0,3
0,4
0,7
0,6
0,5
2
0,7
Bayam
Kangkung
Daun Pepaya
Daun Singkong
Kol
Sawi Hijau
Seledri
Selada
Tomat
Paprika
Cabai
Buncis
Kacang Panjang
Bawang Putih
Bawang Merah
Kentang
Lobak
Wortel
Brokoli
Kembang Kol
Asparagus
Jamur
0,8
1
2,1
1,2
1,2
1,2
0,7
0,6
1,2
1,4
0,3
1,2
2,5
1,1
0,6
0,3
0,7
0,9
0,5
0,9
0,6
1,2
Kacang Kedelai
Kacang Tanah
Kacang Hijau
Jagung
Kedelai Bubuk
Kecap Kental
Tahu
Susu Kedelai
Taoge
Tempe
4,9
2
4,1
2,9
2,5
0,6
0,1
0,1
0,7
0