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EDS 249
CSUS Spring Semester 2010
Acknowledgements
Adapted from
Hart, S. R., Jeltova, I., & Brock, S. E. (in preparation).
Assessing, identifying, and treating bipolar disorder
at school. New York: Springer.
Lecture Outline
Diagnosis
Course
Co-existing Disabilities
Associated Impairments
Etiology Prevalence & Prognosis
Etiology,
Treatment
Best Practices for School Psychologists
EDS 249
CSUS Spring Semester 2010
Lecture Goals
You will
1. gain an overview of bipolar disorder.
2. acquire a sense of what is like to have bipolar
disorder
disorder.
3. learn what to look for and what questions to
ask when screening for bipolar disorder.
4. understand important special education issues,
including the psycho-educational evaluation of
a student with a known or suspected bipolar
disorder.
4
Presentation Outline
Diagnosis
Course
Co-existing Disabilities
Associated Impairments
Etiology Prevalence & Prognosis
Etiology,
Treatment
Best Practices for School Psychologists
EDS 249
CSUS Spring Semester 2010
Diagnosis
NIMH (2007)
DSM-IV-TR Diagnosis
1. Importance of early diagnosis
2. Pediatric bipolar disorder is especially challenging to identify.
Characterized by severe affect dysregulation, high levels of
agitation, aggression.
Relative to adults, children have a mixed presentation, a chronic
course, poor response to mood stabilizers, high co-morbidity
co morbidity
with ADHD
3. Symptoms similar to other disorders.
For example, ADHD, depression, Oppositional Defiant Disorder,
Obsessive Compulsive Disorder, and Separation Anxiety
Disorder.
4. Treatments differ significantly.
5. The school psychologist may be the first mental health
professional to see bipolar.
Faraon et al. (2003)
DSM-IV-TR Diagnosis
Diagnostic Classifications
Bipolar I Disorder
1.
Bipolar II Disorder
2.
APA (2000)
EDS 249
CSUS Spring Semester 2010
DSM-IV-TR Diagnosis
Diagnostic Classifications
Cyclothymia
3.
4.
APA (2000)
10
DSM-IV-TR Diagnosis
APA (2000)
11
DSM-IV-TR Diagnosis
APA (2000)
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CSUS Spring Semester 2010
Example
Irritability: Energized,
Energized angry
angry, raging
raging, or
intensely irritable mood, out of the blue
or as an inappropriate reaction to external
events for an extended period of time.
In reaction to meeting a
substitute teacher, a child
flies into a violent 20minute rage.
13
Example
14
Example
Distractibility: Increased
inattentiveness beyond childs
baseline attentional capacity.
Excessive Involvement in
Pleasurable or Dangerous
Activities: Sudden unrestrained
participation in an action that is likely
to lead to painful or very negative
consequences.
A previously mild-mannered
child may write dirty notes to the
children in class or attempt to
jump out of a moving school
bus.
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16
DSM-IV-TR Diagnosis
Hypomanic Criteria
Same symptoms
Diff
Differences
ffrom Manic
M i E
Episode
i d
Length of time
Impairment not as severe
May not be viewed by the individual as pathological
APA (2000)
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DSM-IV-TR Diagnosis
APA (2000)
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EDS 249
CSUS Spring Semester 2010
DSM-IV-TR Diagnosis
1) Depressed mood
2) Diminished interest in activities
3) Significant weight loss or gain
4) Insomnia or hypersomnia
5) Psychomotor agitation or retardation
6) Fatigue/loss of energy
7) Feelings of worthlessness/inappropriate guilt
8) Diminished ability to think or concentrate/indecisiveness
9) Suicidal ideation or suicide attempt
APA (2000)
19
DSM-IV-TR Diagnosis
APA (2000)
20
Example
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EDS 249
CSUS Spring Semester 2010
Example
Insomnia or Hypersomnia:
Difficulty falling asleep, staying
asleep, waking up too early or
sleeping longer and still feeling
tired.
Psychomotor
Agitation/Retardation: Looks
restless or slowed down.
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Example
23
Example
Hopelessness: Negative
thoughts or statements about
the future.
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EDS 249
CSUS Spring Semester 2010
DSM-IV-TR Diagnosis
APA (2000)
25
DSM-IV-TR Diagnosis
Rapid-Cycling Specifier
APA (2000)
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CSUS Spring Semester 2010
Adults
Juveniles
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Adults
Mania includes marked euphoria, grandiosity, and irritability
Adolescents
Mania is frequently associated with psychosis, mood lability, and
depression.
Prepubertal Children
Mania involves markedly labile/erratic changes in mood, energy
levels, and behavior.
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CSUS Spring Semester 2010
Adolescent
Male Gender
67.5%
48.2%
Chronic Course
57.5%
23.3%
Episodic Course
42.5%
76.8%
Attention-deficit/Hyperactivity Disorder
38.7%
8.9%
35.9%
10.7%
31
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NIMH Roundtable
Narrow Phenotype
Broad Phenotype
NIMH (2001)
33
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CSUS Spring Semester 2010
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Presentation Outline
Diagnosis
Course
Co-existing Disabilities
Associated Impairments
Etiology Prevalence & Prognosis
Etiology,
Treatment
Best Practices for School Psychologists
36
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Remission
Relapse
Recovery
Chronic
37
Presentation Outline
Diagnosis
Course
Co-existing Disabilities
Associated Impairments
Etiology Prevalence & Prognosis
Etiology,
Treatment
Best Practices for the School Psychologist
Psycho-Educational Assessment
Special Education & Programming Issues
School-Based Interventions
38
Co-existing Disabilities
Anxiety Disorders
Conduct Disorder
0 to 40%
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Co-existing Disabilities
AD/HD Criteria Comparison
Bipolar Disorder (mania)
AD/HD
2. Distractibility
3. Is often on the go or
often acts as if driven by
a motor
Co-existing Disabilities
Developmental Differences
Unipolar Depression
Schizophrenia
41
Presentation Outline
Diagnosis
Course
Co-existing Disabilities
Associated Impairments
Etiology Prevalence & Prognosis
Etiology,
Treatment
Best Practices for School Psychologists
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Associated Impairments
Suicidal Behaviors
Prevalence of suicide attempts
40-45%
43
Associated Impairments
Cognitive Deficits
Executive Functions
Attention
Memory
Sensory-Motor Integration
Nonverbal Problem-Solving
Academic Deficits
Mathematics
44
Associated Impairments
Psychosocial Deficits
Relationships
Peers
Family members
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EDS 249
CSUS Spring Semester 2010
Presentation Outline
Diagnosis
Course
Co-existing Disabilities
Associated Impairments
Etiology Prevalence & Prognosis
Etiology,
Treatment
Best Practices for the School Psychologists
46
Etiology
47
Etiology
Genetics
1. Family Studies
2. Twin Studies
MZ = .67; DZ = .20 concordance
3. Adoption Studies
4. Genetic Epidemiology
Early onset BD = confers greater risk to relatives
5. Molecular genetic
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Etiology
Neuroanatomical differences
White matter hyperintensities.
Small abnormal areas in the white
matter of the brain (especially in
the frontal lobe).
Smaller amygdala
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Etiology
Neuroanatomical differences
Reduced gray matter volume in
the dorsolateral prefrontal
cortex (DLPFC)
Bilaterally larger basal ganglia
Specifically larger putamen
DLPFC
Basal Ganglia
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51
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Prognosis
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Prognosis
Outcome by subtype
M
More
chronic;
h i more episodes
i d with
ith shorter
h t iinter-episode
t
i d
intervals; more major depressive episodes; typically
present with less intense and often unrecognized manic
phases; tend to experience more anxiety.
Cyclothymia
Bipolar Disorder II
Bipolar Disorder I
Presentation Outline
Diagnosis
Course
Co-existing Disabilities
Associated Impairments
Etiology Prevalence & Prognosis
Etiology,
Treatment
Best Practices for School Psychologists
54
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Treatment
Psychopharmacological
DEPRESSION
Mood Stabilizers
Anti-Obsessional
Anti-Depressant
Lamictal
Atypical Antipsychotics
Zyprexa, Seroquel,
Risperdal, Geodon, Abilify
Anti-Anxiety
Zyprexa
Atypical Antipsychotics
Wellbutrin
Mood Stabillizers
Paxil
MANIA
Benzodiazepines
Klonopin, Ativan
55
Treatment
Psychopharmacology Cont.
Lithium:
History
Side effects/drawbacks
Blood levels drawn frequently
Weight gain
Increased thirst,
thirst increased urination
urination, water retention
Nausea, diarrhea
Tremor
Cognitive dulling (mental sluggishness)
Dermatologic conditions
Hypothyroidism
Birth defects
Benefits & protective qualities
Brain-Derived Neurotropic Factor (BDNF) & Apoptosis
Suicide
56
Treatment
Therapy
Psycho-Education
Family Interventions
Multifamily Psycho-education Groups (MFPG)
Cognitive Behavioral Therapy (CBT)
Cognitive-Behavioral
RAINBOW Program
Interpersonal and Social Rhythm Therapy (IPSRT)
Schema-focused Therapy
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Treatment
Alternative Treatments
Light Therapy
Electro-Convulsive Therapy (ECT) & Repeated
Transcranial Magnetic Stimulation (r-TMS)
Circadian Rhythm
Melatonin
Nutritional Approaches
Omega-3 Fatty Acids
58
Presentation Outline
Diagnosis
Course
Co-existing Disabilities
Associated Impairments
Etiology, Prevalence & Prognosis
Treatment
Best Practices for School Psychologists
59
Grade retention
Learning disabilities
Special Education
Required tutoring
Adolescent onset = significant disruptions
Before onset
71% good to excellent work effort
58% specific academic strengths
83% college prep classes
After onset
67% significant difficulties in math
38% graduated from high school
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Psycho-Educational Assessment
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Psycho-Educational Assessment
Testing Considerations
Who are the involved parties?
Student
Teachers
Parents
Others?
Release of Information
Referral Question
62
Psycho-Educational Assessment
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Psycho-Educational Assessment
ED Criteria
64
Psycho-Educational Assessment
OHI Criteria
Psycho-Educational Assessment
ED
OHI
Can be an accurate
representation.
Represents the
presentation of the disorder.
Represents
disorder.
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Psycho-Educational Assessment
Family History
Health History
Medical History
67
Psycho-Educational Assessment
Vision/Hearing
Any medical conditions that may be impacting
presentation?
M di ti
Medications
68
Psycho-Educational Assessment
Observations
Interviews
Who?
Questionnaires, phone calls, or face-to-face?
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Psycho-Educational Assessment
Socio-Emotional Functioning
Rating Scales
General
Child-Behavior Checklist (CBCL)
Behavior Assessment System for Children (BASC-II)
Devereux Scales of Mental Disorders (DSMD)
Mania
Washington University in St. Louis Kiddie Schedule for
Affective Disorders and Schizophrenia (WASH-U KSADS)
Young Mania Rating Scale
General Behavior Inventory (GBI)
Depression
Beck Depression Inventory (BDI)
Hamilton Rating Scale for Depression
Reynolds Adolescent Depression Scale (RADS-2)
70
Psycho-Educational Assessment
Rating Scales
Comorbid conditions
Attention
Conners Rating Scales
Brown Attention-Deficit Disorder Scales for Children and
Adolescents
Conduct
Scale
S l ffor Assessing
A
i E
Emotional
ti
l Di
Disturbance
t b
(SAED)
Anxiety
Revised Childrens Manifest Anxiety Scale (RCMAS)
Informal Measures
Sentence Completions
Guess Why Game?
71
Psycho-Educational Assessment
Cognitive Assessment
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Psycho-Educational Assessment
Memory
Auditory
Visual
Visual-Motor Integration
73
Psycho-Educational Assessment
Executive Functions
Rating Scales
Behavior Rating Inventory of Executive Functions
(BRIEF)
Comprehensive Behavior Rating Scale for Children
Assessment Tools
NEPSY
Delis-Kaplan Executive Function Scale
Cognitive Assessment System (CAS)
Conners Continuous Performance Test
Wisconsin Card Sorting Test
Trailmaking Tests
74
Psycho-Educational Assessment
The Report
Referral Question
Background (e.g., developmental, health, family, educational)
Socio-Emotional Functioning (including rating scales,
observations interviews,
observations,
interviews and narrative descriptions)
Cognitive Functioning (including Executive Functions &
Processing Areas)
Academic Achievement
Summary
Recommendations
Eligibility Statement
Delivery of information
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Mental Health
Medi-Cal/Access to mental health services
SSI
77
Developing a Plan
IEP
504
78
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School-Based Interventions
Counseling
Individual or group?
Goal(s)
Crisis Intervention
80
School-Based Interventions
Education
Coping skills
Social skills
Suicidal ideation/behaviors
Substance use
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School-Based Interventions
Specific Recommendations
1.
2.
3.
4.
5.
6.
7.
82
References
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Adolescent Psychiatry, 46, 107-125.
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental
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Baum, A. E., Akula, N., Cabanero, M., Cardona, I., Corona, W., Klemens, B., Schulze, T.
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