Association Between Helicobacter Pylori Infection and

estimated Glomerolus Filtration Rate

ABSTRACTS
Maharani K*, Damayanti A**, Kusnanto P**, Pramana TY**,
Harmono T**
*Resident Internal Medicine Medical Faculty Sebelas Maret University
**Staff of Gastroenterohepatology Department Sebelas Maret University
Background : It is generally known that Helicobacter pylori (H Pilory)
infection is directly associated with progression of renal dysfunction. Many
reports suggest that chronic H pilory infections may be associated with
atherosclerosis and inflammations. Atherosclerosis and inflammation will
decrease renal function. The aim of this study was to investigate the
association between Helicobacter pilory infection and creatinin clearance
in patient with dyspepsia.
Methods : This retrospective study was conducted between Januari 2013
until Desember 2013 in Moewardi Hospital Surakarta. Inclusion criteria
was dyspepsia syndrom. Exclusion criteria was chronic kidney disease,
chronic liver disease, malignancy, infection. Modification of diet in renal
disease equation was used to count estimated glomerolus filtration rate
(eGFR).H pylory infection define by positive biopsi specimen from
endoscopy
esofago gastro duodenal. Statistical analysis using
independence t test and pearson correlation test with SPSS 20, significant
if p<0,05.
Result : There were 60 patient, 20 with positive H pilory and 40 with
negative H pilory. The mean creatinin was 1,12 + 0,654 mg/dL, mean
ureum 30,45 + 30,34, and mean eGFR 61,34 + 21,34 ml/m2 (satuan
salah). There was negative correlation between h pilory infection and
eGFR in patient with syndrom dyspepsia (p:0,002, r:-0,453)
Conclusion : This study demonstrated that H pilory infection was
associated with lower eGFR in patient with dyspepsia syndrom
Key: Dyspepsia, H. Pylori, Creatin Clearance Test

The Association Between Ferritin Serum and Degree of

Severity Cirrhotic By Child Pugh Turcotte Score
ABSTRACTS
Adhyaksari A*, Damayanti A**, Kusnanto P**, Pramana TY**,
Harmono T**
*Resident Internal Medicine Medical Faculty Sebelas Maret University
**Staff of Gastroenterohepatology Department Sebelas Maret University
Background : Chronic liver disease causes aberrant formation of fibrous
tissue that impedes normal liver function, ultimately resulting in liver
cirrhosis. Iron uptake can occur within the hepatic parenchyme or within
the various nodules that form in a cirrhotic liver, termed siderotic nodules,
this parenchyme changes will aggravate the decrease of liver function.
The aim of this study was to investigate the association between ferritin
serum and degree of severity cirrhotic by child pugh turcotte score
Methods : This retrospective study was conducted between Januari 2013
until Desember 2013 in Moewardi Hospital Surakarta. Inclusion criteria
was cirhhotic patient. Exclusion criteria was chronic kidney disease,
infection, metabolic diseases, and chronic heart failure. Degree severity of
cirhhotic was measured by Child Pugh Turcotte score. Statistical analysis
using independence t-test and pearson correlation test with SPSS 20,
significant if p < 0,05.
Result : There was 60 patient, 35 male and 25 female. Mean age was
48,34 + 12,23. There was 30 patient with hepatitis B, 20 patient with
hepatitis C. The child pugh turcotte score was 12 patient (child pugh A),
28 patient (child pugh B), and 20 patient (child pugh C). There was
positive correlation between ferritin serum and child pugh turcotte score
(p : 0,002, r : -0,453)
Conclusion : This study demonstrated that increase ferritin serum was
associated with severity liver disease measured by Child Pugh Turcotte
score
Key : Cirrhotic, Ferritin serum, Child Pugh Turcotte Score, Hepatitis