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Endometriosis of ovary
Specialty
urology
ICD-10
N80.1
ICD-9-CM
617.1
[edit on Wikidata]
1Pathophysiology
2Treatment
o
2.1Medication
2.2Surgery
3References
Pathophysiology[edit]
It is caused by endometriosis,[1] and formed when a tiny patch of endometrial tissue (the mucous
membrane that makes up the inner layer of the uterine wall) bleeds, sloughs off, becomes
transplanted, and grows and enlarges inside the ovaries. As the blood builds up over months and
years, it turns brown. When it ruptures, the material spills over into the pelvis and onto the surface of
the uterus, bladder, bowel, and the corresponding spaces between.
Treatment[edit]
Treatment for endometriosis can be medical or surgical.
Medication[edit]
Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used first in patients with pelvic pain,
particularly if the diagnosis of endometriosis has not been definitively (excision and biopsy)
established. The goal of directed medical treatment is to achieve ananovulatory state. Typically, this
is achieved initially using hormonal contraception. This can also be accomplished with progestational
agents (i.e., medroxyprogesterone acetate), danazol, gestrinone, or gonadotropin-releasing
hormone agonists (GnRH), as well as other less well-known agents. These agents are generally
used if oral contraceptives and NSAIDs are ineffective. GnRH can be combined
withestrogen and progestogen (add-back therapy) without loss of efficacy but with fewer
hypoestrogenic symptoms. These medications are often ineffective in treating endometriomas and
any relief is short lived while taking the medications. Hormonal treatment has a large number of
sometimes permanent side effects, such as hot flushes, loss of bone mass, deepening of voice,
weight gain, and facial hair growth.
Surgery[edit]
Laparoscopic surgical approaches include excision of ovarian adhesions and of endometriomas.
Endometriomas frequently require surgical removal and excision is considered to be far superior in
terms of permanent removal of the disease and pain relief. Surgery can sometimes have the effect
of improving fertility but can have the adverse effect of leading to increases in cycle day 2 or 3 FSH
for many patients.[citation needed] Laser surgery and cauterization are considered to be far less effective and
only burn the top layer of endometrial tissue, allowing for the endometrioma and endometriosis to
grow back quickly. Likewise, endometrioma drainage or sclerotherapy are somewhat controversial
technique for removing endometriomas with varied degrees of success. Conservative surgery can
be performed to preserve fertility in younger patients but as earlier stated can have the effect of
raising FSH values and making the ovaries less productive, especially if functional ovarian tissue is
removed in the surgical process.[citation needed] Operative laparoscopic surgery can provide pain relief and
improved fertility. Radical surgical options could include singular or bilateral oophorectomy. [2][3]
References[edit]
1.
2.
Jump up^ "What You Need To Know About Ovarian Cysts, Common
Types". HealthCentral.
3.
Endometriosis of ovary
Female infertility
Anovulation
Poor ovarian reserve
Mittelschmerz
Oophoritis
Ovary
Ovarian apoplexy
Ovarian cyst
Corpus luteum cyst
Internal
Adnexa
Female infertility
Fallopian tube obstruction
Fallopian tube
Hematosalpinx
Hydrosalpinx
Salpingitis
Asherman's syndrome
Dysfunctional uterine bleeding
Endometrial hyperplasia
Endometrial polyp
Endometriosis
Endometritis
flow
Amenorrhoea
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Endometrium
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