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DEXAMETHASONE
Brand name: Cortastat
Classification: Corticosteroid, Anti-inflammatory agents
Indication: Management of cerebral edema, Diagnostic agent in adrenal disorders, Relieves inflammation, Allergic
disorders, Asthma, Arthritis
Mechanism of Action: Dexamethasone suppresses inflammation and the normal immune response by stabilizing
leukocyte lysosomal membranes; suppresses immune response; stimulates bone marrow; and influences protein, fat
and carbohydrate metabolism.
Contraindication: Hypersensitivity, Active untreated infection, Lactation, Systemic fungal infection
Adverse Effect: Skin rash, Swollen face, legs or ankles, Vision problems, Cold or infection that last for a long time,
Muscle weakness, Black or tarry stool
Nursing Responsibilities:
Monitor intake and output of patient.
Observe the patient for peripheral edema, steady weight gain, rales or crackles or dyspnea.
For patients with cerebral edema, assess then for level of consciousness changes and headache during the
therapy.
Instruct patient to avoid people with known infection and contagious illnesses as corticosteroids causes
immunosuppression and may mask symptoms of infection