Академический Документы
Профессиональный Документы
Культура Документы
Cited
Hill 1
Works Cited
Primary Sources
Browne, Janet. "Darwin the Young Adventurer." The Magazine of the National Endowment for
the Humanities. Last modified May 2009.
http://www.neh.gov/humanities/2009/mayjune/feature/darwin-the-young-adventurer.
Charles Darwin became famous for his publication, The Origin of Species, in which he
famously detailed the relatively unexplored concept of heredity and evolution by means
of natural selection. This website detailed Charles Darwin and his exploits and research
on the Galapagos Islands. This article helped me understand how genetics is the cause of
natural selection and evolution.
Callaway, Ewen. "UK Scientists Gain License to Edit Genes in Human Embryos." Nature,
February 1, 2016.
The field of genetics has been encountering new applications and fields of study and
research ever since the discovery of the double helix in 1953. This article detailed a
recently utilized application of genetics: editing human DNA. This article helped me
understand how the discovery of the double helix has led genetic science to encounter
new applications, even in the modern day.
Charlotte, Auerbach. Genetics in the Atomic Age. Washington DC, DC: Essential Books, 1965.
During the 1950s, the atomic age placed emphasis on the study of genetics, casting it in a
new light. This book detailed the effects of radiation on genetic mutations, and related
genetic anomalies, in response to public fear of radiation on their health. This book
helped me understand what spurred the study of genetics in the 1950s.
Cold Spring Harbor Laboratory. "Linus Pauling's Incorrect Model of the DNA Structure, James
Watson." DNA Learning Center. https://www.dnalc.org/view/15451-linus-pauling-sincorrect-model-of-the-dna-structure-james-watson.html.
Linus Pauling was a third, relatively unknown party in the race to discover the double
helix, published a paper on his proposed triple helical model on the structure of DNA,
however, his model was similar to Watson and Crick's earlier failed model. This website
contained James Watson's commentary regarding Linus Pauling's proposition. This
website helped me understand the race to discover DNA, and how all the scientists in the
race exchanged ideas and essentially worked together.
Crick, Francis. Letter, March 19, 1953. Salk Institutue for Biomedical Studies. San Diego, CA.
Francis Crick and James Watson discovered the double helical structure of DNA, thereby
thrusting the scientific community into a new world of possibilities. This is a letter
written by Francis Crick to his son, Michael, detailing his and Watson's discoveries. This
letter helped me understand the nature of the discovery and the facets of the double helix.
Works
Cited
Hill 2
Franklin, Rosalind. "Specific Optical Rotation of Nucleic Acid." Last modified November 28,
1951. Digital file.
Previous to Watson and cricks' famous discovery of the double helix, Rosalind Franklin
conducted groundbreaking research to photograph the structure of DNA. This document
is a letter from Franklin discussing the rotation of DNA molecules in a helical
arrangement. This document helped me understand how Watson, Crick, and Franklin
exchanged information to discover the double helix.
Franklin, Rosalind, and Raymond Gosling. "Satirical Note Announcing the Death of the DNA
Helix." Last modified July 18, 1952. Digital file.
The first type of helix proposed by Watson and Crick was a triple helix; when showed to
Franklin, she derisively and immediately dismissed the model. This document is a
satirical note written by Franklin, mocking Watson and Crick and their three-stranded
model. This note helped me understand how scientists worked together to discover the
double helix.
"How I Discovered DNA - James Watson." Video file, 20:14. YouTube. Posted by TED-Ed, July
26, 2013. https://www.youtube.com/watch?v=RvdxGDJogtA.
James Watson and Francis Crick exchanged ideas and information with other scientists of
the time,and compiled their information, to create an accurate model of the double helical
structure of DNA. This video is of James Watson lecturing on his discovery of the
double helix. This video helped me understand the process by which the double helix
was discovered.
Works
Cited
Hill 3
National Human Genome Research Institute. "A Guide to Your Genome." Last modified
October 2007. Digital file.
The 21st century has seen a plethora of advances in genetics, specifically in regards to the
human genome. This pamphlet, put out by the National Human Genome Research
Institute, provided information on what the human genome exactly is. This pamphlet
helped me understand the new fields and topics of genetics encountered following the
discovery of the double helix.
National Institutes of Health. "A Brief History of the Human Genome Project." National Human
Genome Research Institute. Last modified November 8, 2012.
http://www.genome.gov/12011239.
The discovery of the double helix allowed scientists to delve deeper into the world of
genetics of living creatures; one such project following this theme was the Human
Genome Project, which aimed to sequence the entire human genome. This website
detailed the project and provided information regarding the effects the project could have
on the world of genetics. This website helped me understand how scientists encountered
far-reaching effects of DNA following the discovery of the double helix.
Works
Cited
Hill 4
The New York Times (New York City, NY). "Rapist Convicted on DNA Match." February 5,
1988.
While fingerprinting has long been a staple of forensics, the discovery of the double helix
and subsequent scientific discoveries has allowed scientists to convict criminal based on
DNA present at crime scenes. Serial rapist Tommie Lee Jones was the first criminal
convicted on the basis of genetics. This article details the convicting and arrest of
Jones. This article helped me understand how genetics encountered a plethora of new
applications as a result of discovering the double helix and gaining a further
understanding of DNA.
Works
Cited
Hill 5
Them! Produced by David Weisbart. Directed by Gordon Douglas. Warner Brother Pictures,
1954.
Following the nuclear bombings of Hiroshima and Nagasaki, the public's fear of nuclear
radiation on genetic mutations was at an all time high; the scientific community
responded by lacing more emphasis on finding the structure of DNA. This movie centers
around mutant ants that gained their large size and ferocity as a result of radiation from a
nuclear bomb. This movie helped me understand the public fear of radiation following
the nuclear ending of World War II.
Turner, Leigh. "A Sheep Named Dolly." University of Winnipeg, April 15, 1997.
The cloning of the sheep named Dolly was the first instance of scientists using DNA
from a living organism to create an exact replica of that organism. This article detailed
the cloning of Dolly and its potential repercussions on genetic science. This article
helped me understand how the discovery of the double helix allowed scientists to
encounter new possibilities to explore genetics.
Watson, James. The Double Helix; A Personal Account of the Discovery of the Structure of
DNA. New York City, NY: Atheneum, 1968.
In 1953, James Watson and Francis Crick completed their model of the double helix,
following the exploration of the matter by several major scientists before them. This
book detailed the journey to discover the double helix form the account of James Watson,
one of the scientists credited for the groundbreaking discovery. This book helped me
understand the process by which the double helix was uncovered by Watson and Crick.
Watson, James, and Francis Crick. James Watson and Francis Crick to Linus Pauling, March 21,
1953. Linus Puling and the Race for DNA. Oregon State University, Corvallis, OR.
James Watson and Francis Crick, Linus Pauling, and Maurice Wilkins and Rosalind
Franklin were the three most prominent scientists working in the early 1950s to uncover
the structure of DNA. This letter details Watson and Crick's exchange with Linus Pauling
regarding their double helical structure. This letter helped me understand how Watson
and Crick exchanged ideas to discover the double helix.
Works
Cited
Hill 6
Wilkins, Maurice. Maurice Wilkins to Francis Crick, n.d. National Library of Medicine. National
Institutes of Health, Bethesda, MD.
Maurice Wilkins worked closely with Rosalind Franklin at King's College, while Francis
Crick research alongside James Watson and Cambridge University's Cavendish
Laboratory. This is a letter from Maurice Wilkins to Francis Crick discussing his and
Franklin's recent research regarding the structure of DNA. This letter helped me
understand how ideas were exchanged among scientists to create the comprehensive
model of the double helix.
Works
Cited
Hill 7
Secondary Sources
Blamire, John. "Semiconservative." DNA Replication. Last modified 200.
http://www.brooklyn.cuny.edu/bc/ahp/BioInfo/REP/DR.Semi.html.
In 1958, the process of semiconservative replication was discovered, revealing how DNA
transmitted its sequences of nucleotide bases. This website discussed the process of
semiconservative replication. This website helped me understand how DNA replicates
and how the discovery of the double helix led to a more in-depth understand of genetics.
Dahm, Ralf. Friedrich Miescher and the Discovery of DNA. Tel Aviv, Israel: Tel Aviv
University, 2004.
Friedrich Miescher's research regarding DNA set a foundation for later scientists to build
upon and to discover more key elements regarding the function of DNA. This paper
detailed not only Miescher's achievements, but provided a brief insight into the
achievements of many other scientists, providing a timeline of DNA research up to the
modern day. This paper helped me understand and connects events in the history of
genetic research.
"The DNA Double Helix Discovery HHMI BioInteractive Video." Video file, 17:08.
YouTube. Posted by BioInteractive, August 26, 2014.
https://www.youtube.com/watch?v=1vm3od_UmFg.
The discovery of the double helix was rooted in the research, not only of earlier
geneticists, but also the research of scientists alongside Watson and Crick. This video
detailed the process by which the double helix was discovered in 1953. This video
helped me understand how the discovery of the double helix came from upon the
shoulders of multitudes of scientists before it.
"DNA Double Helix: How James Watson and Francis Crick Cracked the Secret of Life." Video
file, 6:13. YouTube. Posted by TheGuardian, April 29, 2013.
https://www.youtube.com/watch?v=QWwKkGmwhsA.
James Watson and Francis Crick are credited with creating the first correct model of
DNA as a double helix structure. This video explained the discovery and model of the
double helix. This video helped me understand how the structure of DNA as a double
helix came to be and how Watson and Crick used information from several other
scientists to come to their conclusion.
DNA Learning Center. "DNA Timeline: DNA Science from Mendel to Today." DNA
Interactive. Last modified 2003. http://www.dnai.org/timeline/.
The history of genetic research is long and complex. This website provided a
comprehensive timeline of the study of DNA and genetics. This website helped me
understand how far genetics has come since the days of Mendel and Darwin, and where
genetic science is in the modern day.
Works
Cited
Hill 8
. "A Gene Is a Discrete Sequence of DNA Nucleotides." DNA From the Beginning.
http://www.dnaftb.org/23/bio.html.
In 1977, British biochemist Frederick Sanger sequenced the DNA of a virus;this was the
first organism's DNA to ever be sequenced. This website detailed Sanger's life and
scientific accomplishments. This website helped me understand how scientists were able
to further explore the uses and facets of DNA following the discovery of the double
helix.
. "A Half DNA Ladder Is a Template for Copying the Whole." DNA From the
Beginning. http://www.dnaftb.org/20/bio.html.
Matthew Messelson and his colleague, Franklin Stahl, discovered semiconservative
replication, the process by which DNA duplicates and passes on genetic traits. This
website detailed the life of Messelson and provided information regarding the process of
semiconservative replication. This website helped me understand how the discovery of
the double helix helped scientists explore new facets of DNA in relation to genetic
science.
"Dr. Rosalind Franklin: A Life in Discovery." Rosalind Franklin University of Medicine and
Science. https://rosalindfranklin.edu/about/dr-rosalind-franklin/.
Rosalind Franklin experimented heavily with x-ray crystallography, a technique which,
by her hand, would become integral to the final discovery of the double helix. This
website briefly detailed the life, accomplishments, and importance of Rosalind Franklin
and her contributions to the world of science and genetics. This website helped me
understand how important Rosalind Franklin was to the final discovery of the double
helix.
Works
Cited
Hill 9
"How Does DNA and the Genetic Code Work? At Science Tutorial Video." Video file, 28:53.
YouTube. Posted by TheGuardian, February 19, 2013.
https://www.youtube.com/watch?v=9WECD5lKiHk.
DNA contains a specifically ordered amount of phosphate groups that create amino acids,
which determine proteins that determine genetic traits. This video breaks down and
explains the function of DNA in that regard. This video helped me understand exactly
how DNA functions to determine genetic traits.
Klug, Aaron. The Discovery of the DNA Double Helix. Amherst, MA: University of
Massachusetts Amherst, 2004.
DNA is a complex molecule with functions as diverse and complicated as its functions.
This report details the functions of DNA and provides brief information regarding
methods of discovering the structure of DNA. This report helped me understand how
DNA functions and how its iconic structure came to be widespread knowledge.
Pray, Leslie A. "Discovery of DNA Structure and Function: Watson and Crick." Scitable. Last
modified 2008. http://www.nature.com/scitable/topicpage/discovery-of-dna-structureand-function-watson-397.
DNA is the self-replicating material that contains the genetic information for any and all
living organisms on Earth. This website provided information regarding the structure,
function, and history of DNA. This website helped me understand how DNA affects all
life on Earth.
Ulaby, Neda. "Movie Mutants Givea Face to Our Nuclear Fears." National Public Radio. Last
modified March 30, 2011. http://www.npr.org/2011/03/30/134950737/movie-mutantsgive-a-face-to-our-nuclear-fears.
During the 1950s, pop culture exacerbated the effects of nuclear radiation on genetics by
way of exaggerated radioactive monsters. This article detailed the views of society on
radiation in relation to the pop culture present at the time. This article helped me
understand what triggered Watson and Crick's discovery of the double helix.
Works
Cited
Hill 10