Data Management and Analysis in Health Care

Department of Nursing, College of Medicine

National Cheng Kung University
Course Syllabus: Spring, 2016
Credit hours: 3
Time: Thursday, 09:10 12:00
Instructors: Hsing-Mei Chen (hsingmei@mail.ncku.edu.tw; phone: 6272)
Shan-Tair Wang (wifetz@hotmail.com; phone: 5760)
TA: Anggi L Wicaksana (anggik.wicaksana@gmail.com; phone: +886-975-217-643)
Dhea Natashia (dns.dhe.nats89@gmail.com; phone: +886-)
Office hours: Wednesday 12:00-13:00 at computer lab (85209), Department of Nursing. You
can make other appointments if needed.
Description:
This course is to provide a basic introduction to data management and analysis as applied
to research hypotheses in health care sciences. The students in this course will learn the basic
knowledge on data management and analysis including the organization of databases and the
use of analytic techniques. The use of statistic software will also be demonstrated in class.
Objectives:
1. Describe the purpose of data management and analysis in the health care related
research.
2. Identify the essential data elements for research hypotheses.
3. Explain and discuss the roles of different statistical testing.
4. Apply the techniques of data analysis in hypotheses testing.
5. Critique the uses of statistical testing from related literature and discuss their
advantages and disadvantages.
Teaching methods:
1. Lectures on the basic knowledge of data management and analysis.
2. Computer lab exercises by using the SPSS statistical analysis.
3. Reading and critique of literature.
Evaluations:
1. Reading of literature examples (20%) and presentation (10%)
Please find research articles in your own area of research as the examples. The written
content should include (but not limited):
a. the title and source of the article
b. the purpose of the study
c. research method (design, sample, name of instruments)
d. the key variables and their descriptive statistics
e. the hypotheses that were tested
f. the method of testing and its rationales as well as the interpretation of results.
g. please upload your weekly written reports to iMoodle (http://moodle.ncku.edu.tw/)
by next Tuesday mid-night after the class.
2. Mid-term and final oral reports (40%, each for 20%, 10-minute):
Please prepare these two 10-minute reports from your homework of reading of
literature examples.
102-2 statistics syllabus

2/17/2016

Page 1 of 11

4. Quizzes (30%)
Expectations: Each student should
1. download class handouts before you come to class. Please download handouts from
iMoodle with your own id and password
2. Download SPSS practice examples via
(1) http://140.116.61.208/moodle/enrol/index.php?id=8, password: spss
(2) Rice Virtual Lab in Statistics http://onlinestatbook.com/rvls.html
3. attend each class on time.
4. read assigned readings and prepare for the quiz before attending classes.
5. actively participate in class discussion and raising questions.
6. maintain the intact of the computer room (no drink and food in the room).
7. turn off cellular phones or pagers in class.
Required Textbooks:
Kellar, S. P. & Lelvin, E. (2013). Munros Statistical methods for health care research (6th
ed.). Philadelphia, PA: Wolters Kluwer/ Lippincott Williams & Wilkin. ISBN 10:
013217863X ISBN 13: 9780132178631
Norusis, M. J. SPSS Statistics Base 17.0 users guide. SPSS Inc.
Norusis, M. J. SPSS Statistics 17.0 Brief Guide. SPSS Inc.
Suggested Textbook:
Huck, S. W. (2011). Reading statistics and research (6th Ed.). Boston, MA: Pearson
Education. ISBN-10: 013217863X ISBN-13: 9780132178631

102-2 statistics syllabus

2/17/2016

Page 2 of 11

Data Management and Analysis in Health Care

Time: Thursday, 9:00 12:00
Place: Computer lab, Kun-Yen Medical Library
Week Date Date
Classes
Instructor
1.
2/25 09:10-10:00 Introduction to statistics
Hsing-Mei Chen
10:10-11:30 Introduction to level of measurement and
Shan-Tair Wang
organizing data
Assigned reading: Munro Chapter 1
11:30-12:00 Example practice
Anggik /Shan-Tair
Wang
2
3/03 09:10-9:20 Quiz-1
Dhea
09:20-11:00 Univariate descriptive statistics I
Shan-Tair Wang
Assigned reading: Chapter 2
11:10-12:00 Example practice
Dhea/Shan-Tair
Wang
Reading example 1 due by 3/8
3
3/10 09:10-9:20 Quiz-2
Anggik
09:20-10:20 Univariate descriptive statistics II
Shan-Tair Wang
Assigned reading: Huck, S. (2008). Chapter 5
(from moodle)
10:30-11:00 Example practice
Anggik/Shan-Tair
Wang
11:10-12:00 Student presentation and discussion-1
Shan-Tair Wang
Hsing-Mei Chen
4
3/17 09:10-9:15 Quiz-3
Dhea
9:15-10:20 Probability and the probability distribution
Shan-Tair Wang
Assigned reading: Chapter 3
10:30-11:00 Example practice
Dhea/Shan-Tair
Wang
11:10-12:00 Student presentation and discussion-2
Shan-Tair Wang
Hsing-Mei Chen
Reading example 2 due by 3/15
5
3/24 09:10-9:15 Quiz-4
Anggik
9:15-10:20 Estimation
Shan-Tair Wang
Required reading: Huck, S. (2008). Chapter 6
(from moodle)
10:30-11:00 Example practice
Anggik/Shan-Tair
Wang
11:10-12:00 Student presentation and discussion-3
Shan-Tair Wang
Hsing-Mei Chen
6
3/31
Spring Break
7
4/07 09:10-9:15 Quiz-5
Dhea
9:15-10:20 Hypothesis testing
Shan-Tair Wang
Required reading: Chapter 4
10:30-11:00 Example practice
Dhea/Shan-Tair
Wang
11:10-12:00 Student presentation and discussion-4
Shan-Tair Wang
Hsing-Mei Chen
Reading example 3 due by 4/5
8
4/14 09:10-9:15 Quiz-6
Anggik
102-2 statistics syllabus

2/17/2016

Page 3 of 11

9:15-10:20 t-tests: independent t, paired t tests

Required reading: Chapter 5, 6
10:30-11:00 Example practice
11:10-12:00 Student presentation and discussion-5
Reading example 4 due by 4/19
4/21 09:10-9:15 Quiz-7
9:15-10:20 One-way analysis of variance
Required reading: Chapter 7
10:30-11:00 Example practice

11:10-12:00 Student presentation and discussion-6

10

4/28 9:10-12:00 Mid-term report

11

5/05 09:10-9:15 Quiz-8

9:15-10:20 Nonparametric statistics
Assigned reading: Chapter 5, 6, 7
10:30-11:00 Example practice
11:10-12:00 Student presentation and discussion-7

12

Reading example 5 due by 5/10

5/12 09:10-9:15 Quiz-9
9:15-10:20 Correlation
Required reading: Chapter 11
10:30-11:00 Example practice
11:10-12:00 Student presentation and discussion-8

13

5/19 09:10-9:15 Quiz-10

9:15-10:20 Linear regression
Required reading: Chapter 14
10:30-11:00 Example practice
11:10-12:00 Student presentation and discussion-9

14

15

Shan-Tair Wang
Anggik/Shan-Tair
Wang
Shan-Tair Wang
Hsing-Mei Chen
Dhea
Shan-Tair Wang
Dhea/Shan-Tair
Wang
Shan-Tair Wang
Hsing-Mei Chen
Shan-Tair Wang
Hsing-Mei Chen
Anggik
Shan-Tair Wang
Anggik/Shan-Tair
Wang
Shan-Tair Wang
Hsing-Mei Chen
Dhea
Shan-Tair Wang
Dhea /Shan-Tair
Wang
Shan-Tair Wang
Hsing-Mei Chen
Anggik
Shan-Tair Wang
Anggik/Shan-Tair
Wang
Shan-Tair Wang
Hsing-Mei Chen

Reading example 6 due by 5/17

5/26 09:10-9:15 Quiz-11
Dhea
9:15-10:20 Measures of association: odds ratio and risk ratio Shan-Tair Wang
Required reading: Chapter 13
10:30-11:00 Example practice
Dhea/
Shan-Tair Wang
11:10-12:00 Student presentation and discussion-10
Shan-Tair Wang
Hsing-Mei Chen
6/02 09:10-9:15 Quiz-12
Anggik
9:15-10:20 Chi square tests
Shan-Tair Wang
Assigned reading: Chapter 12
10:30-11:00 Example practice
Anggik/Shan-Tair
Wang

102-2 statistics syllabus

2/17/2016

Page 4 of 11

11:10-12:00 Student presentation and discussion-11

Shan-Tair Wang
Hsing-Mei Chen

Reading example 7 due by 6/7

16

6/9

17

6/16 9:10-12:00 Final report

18

6/23 9:10-12:00 Course evaluation

Shan-Tair Wang
Hsing-Mei Chen
Hsing-Mei Chen

Recommended readings I
D'Alonzo, K. (2004). The Johnson-Neyman Procedure as an alternative to
ANCOVA. Western Journal of Nursing Research, 26(7), 804-812.
http://dx.doi.org/10.1177/0193945904266733
Doane, D., & Seward, L. (2011). Measuring skewness: a forgotten statistic? Journal of
Statistics Education, 19(2).
Engel, D., Woolley, A., Jing, L., Chabris, C., & Malone, T. (2014). Reading the mind in the
eyes or reading between the lines? Theory of mind predicts collective intelligence
equally well online and face-to-face. Plos ONE, 9(12), e115212.
http://dx.doi.org/10.1371/journal.pone.0115212
Erb, H. (1990). A Statistical spproach for calculating the minimum number of animals needed
in research. ILAR Journal, 32(1), 11-16. http://dx.doi.org/10.1093/ilar.32.1.11
Goldman, K. (2000). Reading (an article) between the lines. Health Promotion Practice, 1(4),
305-306. http://dx.doi.org/10.1177/152483990000100403
Lucadamo, A., Accoto, N., & Martini, D. (2012). Power estimation for multiple co-primary
endpoints: a comparison among conservative solutions. Italian Journal of Public
Health, 9(4).
Lydersen, S., Fagerland, M., & Laake, P. (2009). Recommended tests for association in 22
tables. Statist. Med., 28(7), 1159-1175. http://dx.doi.org/10.1002/sim.3531
Moser, B., & Stevens, G. (1992). Homogeneity of variance in the two-sample means test. The
American Statistician, 46(1), 19. http://dx.doi.org/10.2307/2684403
Owen, S., & Froman, R. (1998). Uses and abuses of the analysis of covariance. Research
Nursing Health,21(6), 557-562.
http://dx.doi.org/10.1002/(sici)1098-240x(199812)21:6<557::aid-nur9>3.0.co;2-z
Rafter, J., Abell, M., & Braselton, J. (2002). Multiple comparison methods for means. SIAM
Rev.,44(2), 259-278. http://dx.doi.org/10.1137/s0036144501357233
Razali, N., & Wah, Y. (2011). Power comparisons of Shapiro-Wilk, Kolmogorov-Smirnov,
Lilliefors and Anderson-Darling tests. Journal of Statistical Modeling And
Analytics, 2(1), 21-33.
Royston, P., Altman, D., & Sauerbrei, W. (2005). Dichotomizing continuous predictors in
multiple regression: a bad idea. Statist. Med., 25(1), 127-141.
http://dx.doi.org/10.1002/sim.2331

102-2 statistics syllabus

2/17/2016

Page 5 of 11

Src, B. (2008). A power comparison and simulation study of goodness-of-fit

tests. Computers & Mathematics with Applications, 56(6), 1617-1625.
http://dx.doi.org/10.1016/j.camwa.2008.03.010
Whittingham, M., Stephens, P., Bradbury, R., & Freckleton, R. (2006). Why do we still use
stepwise modelling in ecology and behaviour?. Journal Of Animal Ecology, 75(5),
1182-1189. http://dx.doi.org/10.1111/j.1365-2656.2006.01141.x
Recommended readings II
Altman, D. G., & Bland, J. M. (1995). Statistics notes: Absence of evidence is not evidence
of absence. BMJ, 311, 485.
Anthony, D. (1996). A review of statistical methods in the Journal of Advanced Nursing.
Journal of Advanced Nursing, 24(5), 1089-1094.
Banerjee, A., Jadhav, S. L., & Bhawalkar, J. S. (2009). Probability, clinical decision making
and hypothesis testing, Industry Psychiatry Journal, 18(1), 64-69.
Bell, M. L., Olivier, J., & King, M. T. (2013). Scientific rigour in psycho oncology trials:
why and how to avoid common statistical errors. Psycho-Oncology, 22, 499505.
De Muth, J. E. (2009). Overview of biostatistics used in clinical research. American Journal
of Health-System Pharmacy, 66(1), 70-81.
De Muth, J. E. (2009). Overview of biostatistics used in clinical research. American Journal
of Health-System Pharmacy, 66(1), 70-81.
Fosgate, G. T. (2009). Practical sample size calculations for surveillance and diagnostic
investigations. Journal of Veterinary Diagnostic Investigation, 21(1), 3-14.
Goldman, K. D., & Schmalz, K. J. (2000). Reading (an article) between the lines. Health
Promotion Practice, 1(4), 305-306.
Guyatt, G., Jaeschke, R., Heddle, N., Cook, D., Shannon, H., & Walter, S. (1995). Basic
statistics for clinicians: 1. Hypothesis testing. Canadian Medical Association Journal,
152(1), 27.
Hart, A. (2000). Towards better research: a discussion of some common mistakes in
statistical analyses. Complementary Therapies in Medicine, 8(1), 37-42.
Holmes, T. H. (2004). Ten categories of statistical errors: A guide for research in
endocrinology and metabolism. American Journal of Physiology - Endocrinology &
Metabolism, 286(4), E495-501.
Hou, W., & Carden, D. (2012). Statistics for the no statistician: part II. Southern medical
journal, 105(3), 131-135.
Jairesh, N., Hogerney, M., & Parson, C. (2000). The role of the pilot study: A case
illustration from cardiac nursing research. Applied Nursing Research, 13, 92-96.
Kusuoka, K., & Hoffman, J. I. E. (2002). Advice on statistical analysis for circulation research.
Circulation Research, 91, 662-671. DOI: 10.1161/01.RES.0000037427.73184.C1
Lang, T. (2004). Twenty statistical errors even YOU can find in biomedical research articles.
Croatian Medical Journal, 45, 361-370.
Martin Bland, J., & Altman, D. (1986). Statistical methods for assessing agreement between
two methods of clinical measurement. The lancet, 327(8476), 307-310.
102-2 statistics syllabus

2/17/2016

Page 6 of 11

McCluskey, A., & Lalkhen, A. G. (2007a). Statistics I: data and correlations. Continuing
Education in Anaesthesia, Critical Care & Pain, 7(4), 95-99.
McCluskey, A., & Lalkhen, A. G. (2007b). Statistics II: central tendency and spread of data.
Continuing Education in Anesthesia, Critical Care & Pain, 7(3), 95-99.
McCluskey, A., & Lalkhen, A. G. (2007c). Statistics III: Probability and statistical tests.
Continuing Education in Anesthesia, Critical Care & Pain, 7(5), 167-170.
McCluskey, A., & Lalkhen, A. G. (2007d). Statistics IV: Interpreting the results of statistical
tests. Continuing Education in Anesthesia, Critical Care & Pain, 7(6), 208-212.
Mihaylova, B., Briggs, A., O'Hagan, A., & Thompson, S. G. (2011). Review of statistical
methods for analysing healthcare resources and costs. Health economics, 20(8),
897-916.
Murphy, J. R. (2004). Statistical errors in immunologic research. Journal of Allergy &
ClinAnggik Immunology, 114, 1259-1263.
Phillips, C. V., MacLehose, R. F., & Kaufman, J. S. (2008). (Errors in statistical tests) 3.
Emerging themes in epidemiology, 5(1), 9.
Qualls, M., Pallin, D. J., & Schuur, J. D. (2010). Parametric versus nonparametric statistical
tests: the length of stay example. Academic Emergency Medicine, 17(10), 1113-1121.
Rigby, A. S. (1998). Statistical methods in epidemiology: I. Statistical errors in hypothesis
testing. Disability & Rehabilitation, 20(4), 121-126.
Sequi, M., Campi, R., Clavenna, A., & Bonati, M. (2013). Methods in
pharmacoepidemiology: a review of statistical analyses and data reporting in pediatric
drug utilization studies. European journal of clinical pharmacology, 69(3), 599-604.
Strasak, M. A., Zaman, Q., Pfeiffer, K. P., Gobel, G., & Ulmer, H. (2007). Statistical errors in
medAnggik research-a review of common pitfalls. Swiss Medical Weekly, 137 (3-4),
44-49.
Vail, A., & Gardener, E. (2003). Common statistical errors in the design and analysis of
subfertility trials. Human Reproduction, 18(5), 1000-1004.
Wissing, D. R., & Timm, D. (2012). Statistics for the nonstatistician: Part I. Southern medical
journal, 105(3), 126-130.

102-2 statistics syllabus

2/17/2016

Page 7 of 11

Students Presentation
No Date
Time
1

10

11

3/10

3/17

3/24

4/07

4/14

4/21

5/05

5/12

5/19

5/26

6/02

11:10
-11:35
11:35
-12.00
11:10
-11:35
11:35
-12.00
11:10
-11:35
11:35
-12.00
11:10
-11:35
11:35
-12.00
11:10
-11:35
11:35
-12.00
11:10
-11:35
11:35
-12.00
11:10
-11:35
11:35
-12.00
11:10
-11:35
11:35
-12.00
11:10
-11:35
11:35
-12.00
11:10
-11:35
11:35
-12.00
11:10
-11:35
11:35
-12.00

102-2 statistics syllabus

Students Name
Yulanticha Diaz AA
Nita Fitriana
Ferdy Lainsamputty

Topic
Univariate descriptive statistics I

Roza Marlinda
Univariate descriptive statistics II
Abdu R Kamil
Wahyu Setyarini
Sofyan Indrayana
Anak Agung Istri WK

Probability and the probability

distribution

Masroni Asmai
Ni Made Manik EP

Estimation

Gst. Kade Adi WP

Ida Ayu Ningrat PD

Hypothesis testing

Yulanticha Diaz AA
t-Tests: independent t, paired t tests
Nita Fitriana
Ferdy Lainsamputty
One-way analysis of variance
Roza Marlinda
Abdu R Kamil
Wahyu Setyarini

Nonparametric statistics

Sofyan Indrayana
Anak Agung Istri WK

Correlation

Masroni Asmai
Ni Made Manik EP

Linear regression

Gst. Kade Adi WP

Ida Ayu Ningrat PD

2/17/2016

Measures of association: odds ratio and

risk ratio

Page 8 of 11


Please circle the number that you feel most closely represents your views
Applicable: Do you agree this topic is applicable?
Extremely disagree 1 2 3 4

Extremely agree

Learning: To what extent do you feel you have learned from the class?
Learn nothing 1 2
3 4 5 Learn a lot

Topics
Introduction to Statistics
Univariate descriptive statistic
Probability and the Normal
Distribution
Estimation
Hypothesis testing

Applicable

Learning

Suggestions

1 2 3 4 5 1 2 3 4 5
1 2 3 4 5 1 2 3 4 5
1 2 3 4 5 1 2 3 4 5
1 2 3 4 5 1 2 3 4 5
1 2 3 4 5 1 2 3 4 5

Compare Means with Two

1 2 3 4 5 1 2 3 4 5
Unrelated Groups
Compare Means with Two Related
1 2 3 4 5 1 2 3 4 5
Groups
One Way Analysis of Variance
Correlation Coefficients
Linear Regression
Measures of association: odds ratio
and risk ratio
Chi-Square and Associated
Statistics
Mid-term presentation
Final-term presentation

102-2 statistics syllabus

1 2 3 4 5 1 2 3 4 5
1 2 3 4 5 1 2 3 4 5
1 2 3 4 5 1 2 3 4 5
1 2 3 4 5 1 2 3 4 5
1 2 3 4 5 1 2 3 4 5
1 2 3 4 5 1 2 3 4 5
1 2 3 4 5 1 2 3 4 5

2/17/2016

Page 9 of 11

What was the most important thing you learned?

What was most difficult to understand?

What are your suggestions on lectures and assignments?

To what extent do you feel this course helped you improve the following abilities?
Did nothing 1

Helped a lot

Topics

Improvement Score

Problem solving ability

Evidence-based nursing practice

Exploration of problems

Effective pedagogy

Self-directed learning

102-2 statistics syllabus

2/17/2016

Page 10 of 11

What are your suggestions on the aspects of student participation and evaluation?

What would you like to say about this course?

102-2 statistics syllabus

2/17/2016

Page 11 of 11