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D P Mikhailidis
BSc MSc MD FCPP FCP FRSPH FFPM FRCP FRCPath
Academic Head
DECLARATION OF INTEREST
Attended conferences and gave talks sponsored
by MSD and Genzyme
DECLARATION OF INTEREST
Lead: Guidelines for Medical Management of
Carotid Artery Stenosis (Eur Soc Vasc Surg)
Chairperson: Expert Panel on Small Dense
Low Density Lipoprotein
Co-chairperson: Expert Panel on Post-Prandial
Hypertriglyceridaemia
DECLARATION OF INTEREST
Editor-in-Chief of several journals, including:
Curr Med Res Opin
Expert Opin Pharmacother
Angiology
Curr Vasc Pharmacol
Open Cardiovasc Med J
This threshold for intervention is set at 7.5%. The authors maintain that
there is evidence even at 5%! They state that it is reasonable to consider
moderate intensity statin therapy at a risk of 5 7.5%.
CHD EQUIVALENTS
Diabetes
Peripheral arterial disease
Symptomatic carotid disease
Abdominal aortic aneurysm
Chronic kidney disease (eGFR <60 ml/min/1.73m2
Rheumatoid arthritis (?psoriasis + arthritis, SLE)
SUMMARY
1] Who to treat:
Calculating risk; CHD equivalents; risk engines
2] Targets:
Absolute levels vs % fall of LDL-C
3] What to use to achieve targets:
Statins and what else? PSCK-9?