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implant, thin-film
tran-
I. INTRODUCTION
RTIFICIAL retinas have been ardently desired to recover the sight sense for sight-handicapped people [1].
Recently, artificial retinas using external cameras, stimulus
electrodes, and three-dimensional large scale integrations
(LSIs) have been actively developed for patients suffering
from retinitis pigmentosa and age-related macular degeneration [2][8]. In these cases, electronic photodevices and circuits
substitute for deteriorated photoreceptor cells. The implant
methods can be classified to four types: epiretinal implant,
subretinal implant, suprachoroidal stimulation, and transretinal
stimulation. Among these implant methods, the epiretinal implant has features that the image resolution can be high because
the stimulus signal can be directly conducted to neuron cells
and that living retinas are not seriously damaged.
In our research, we have proposed an artificial retina using
thin-film transistors (TFTs) [9], [10], which can be fabricated
Manuscript received November 14, 2010; accepted November 28, 2010. Date
of publication December 03, 2010; date of current version May 18, 2011. This
work was supported in part by a collaborative research with Seiko Epson Corporation, research project of the Joint Research Center for Science and Technology
of Ryukoku University, grant for research facility equipment for private universities from the Ministry of Education, Culture, Sports, Science and Technology
(MEXT), grant for special research facilities from the Faculty of Science and
Technology of Ryukoku University, and Grant-in-Aid for Scientific Research
from the Japan Society for the Promotion of Science (JSPS). The associate editor coordinating the review of this paper and approving it for publication was
Prof. Gerald Gerlach.
Y. Miura was with the Department of Electronics and Informatics, Ryukoku
University, Seta, Otsu 520-2194, Japan. He is now with the Graduate School of
Materials Science, Nara Institute of Science and Technology, Takayama, Ikoma,
630-0192, Japan (e-mail: t060232@mail.ryukoku.ac.jp).
T. Hachida was with the Department of Electronics and Informatics, Ryukoku
University, Seta, Otsu 520-2194, Japan. He is now with the Graduate School of
Materials Science, Nara Institute of Science and Technology, Takayama, Ikoma,
630-0192, Japan (e-mail: ukkoke1735@hotmail.co.jp).
M. Kimura is with the Department of Electronics and Informatics, Ryukoku
University, Seta, Otsu 520-2194, Japan; the Joint Research Center for Science
and Technology, Ryukoku University, Seta, Otsu 520-2194, Japan; and the Innovative Materials and Processing Research Center, High-Tech Research Center,
Seta, Otsu 520-2194, Japan (e-mail: mutsu@rins.ryukoku.ac.jp).
Color versions of one or more of the figures in this paper are available online
at http://ieeexplore.ieee.org.
Digital Object Identifier 10.1109/JSEN.2010.2096807
MIURA et al.: ARTIFICIAL RETINA USING THIN-FILM TRANSISTORS DRIVEN BY WIRELESS POWER SUPPLY
1565
Fig. 1. Concept model of the artificial retina fabricated on a transparent and flexible substrate and implanted using epiretinal implant.
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Fig. 4. Detected result of the illumination profile versus the output voltage profile.
system should be downsized and bio-compatibility has to be inspected, the supply system is in principle very simple to implant
it into human eyeballs. As a result, the generated power is not
so stable as shown in Fig. 3, which may be because the artificial
retina is fabricated on a insulator substrates, has little parasitic
capacitance, and is subject to the influence of noise. Therefore,
it is necessary to confirm whether the artificial retina can be correctly operated even using the unstable power source.
IV. DETECTED RESULT OF ILLUMINATION PROFILE
The artificial retina with the wireless power supply system is
located in a light-shield chamber, and Vout in each retina pixel
is probed by a manual prober and voltage meter. White light
from a metal halide lamp is diaphragmmed by a pinhole slit, focused through a convex lens, reflected by a triangular prism and
irradiated through the glass substrate to the back surfaces of the
artificial retina on a rubber spacer. The real image of the pinhole
slit is reproduced on the back surface. The detected result of the
Lphoto profile versus the Vout profile is shown in Fig. 4. It is
found that the Lphoto profile can be correctly detected as the
Vout profile even if it is driven using the unstable power source,
although shape distortion is slightly observed, which is due to
the misalignment of the optical system or characteristic variation of TFTs.
V. CONCLUSION
We have evaluated an artificial retina using TFTs driven by
wireless power supply. It was found that the Lphoto profile can
be correctly detected as the Vout profile even if it is driven using
unstable power source generated by inductive coupling, diode
bridge, and Zener diodes. In order to apply the artificial retina
to an actual artificial internal organ, we should further develop
a pulse signal generator appropriate as photorecepter cells, consider the interface between the stimulus electrodes and neuron
cells, investigate the dependence of Vout on Lphoto, which realizes grayscale sensing, etc. However, we think that the above
result means the feasibility to implant the artificial retina into
human eyeballs.
ACKNOWLEDGMENT
The authors would like to thank Dr. H. Hara, Dr. S. Inoue,
Dr. H. Fukushima, and Dr. T. Kamakura of Seiko Epson;
Dr. S. Koide, Dr. Y. Kobashi, and Dr. T. Ito of Epson Imaging
Devices; Dr. T. Munakata of Jedat, and some members in
Mutsu laboratory of Ryukoku University.
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MIURA et al.: ARTIFICIAL RETINA USING THIN-FILM TRANSISTORS DRIVEN BY WIRELESS POWER SUPPLY
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Tomohisa Hachida received the B.E. degree in electronics and informatics from Ryukoku University,
Otsu, Japan, in 2009.
He had been working on research and development
of artificial retinas using thin-film transistors (TFTs).
He is currently a graduate student at Nara Institute of
Science and Technology, Ikoma, Japan.