Metronidazole

Generic Name: metronidazole (me troe NI da zole)

Brand Names: Flagyl, Flagyl 375, Flagyl ER, Flagyl I.V. RTU, Metro I.V.,
Protostat, Flagyl I.V., Metryl

What is metronidazole?
Metronidazole is an antibiotic. It fights bacteria in your body.
Metronidazole is used to treat bacterial infections of the vagina, stomach, skin,
joints, and respiratory tract. This medication will not treat a vaginal yeast
infection.
Metronidazole may also be used for purposes not listed in this medication
guide.

Important information
Take metronidazole for the full prescribed length of time. Your symptoms may
improve before the infection is completely cleared. Skipping doses may also
increase your risk of further infection that is resistant to antibiotics.
Metronidazole will not treat a viral infection such as the common cold or flu. Do
not drink alcohol while you are taking metronidazole and for at least 3 days after
you stop taking it. You may have unpleasant side effects such as fast
heartbeats, warmth or redness under your skin, tingly feeling, nausea, and
vomiting.

Before taking this medicine

You should not use this medication if you are allergic to metronidazole, or if you
are in the first trimester of pregnancy. Tell your doctor if you are pregnant or
plan to become pregnant during treatment.
Before taking metronidazole, tell your doctor if you are allergic to any drugs, or if
you have:

liver disease;

a stomach or intestinal disease such as Crohn's disease;

a blood cell disorder such as anemia (lack of red blood cells) or leukopenia
(lack of white blood cells);
epilepsy or other seizure disorder; or
nerve disorders.
If you have any of these conditions, you may need a dose adjustment or special
tests to safely take this medication.

Metronidazole can pass into breast milk and may harm a nursing baby. Do not
use this medication without telling your doctor if you are breast-feeding a baby.

How should I take metronidazole?

Take metronidazole exactly as prescribed by your doctor. Do not take in larger
or smaller amounts or for longer than recommended. Follow the directions on
your prescription label.
Take the extended-release metronidazole tablet (Flagyl ER) on an empty
stomach, at least 1 hour before or 2 hours after eating a meal. Do not crush,
chew, or break an extended-release tablet. Swallow it whole. Breaking the pill
may cause too much of the drug to be released at one time. Take
metronidazole for the full prescribed length of time. Your symptoms may
improve before the infection is completely cleared. Skipping doses may also
increase your risk of further infection that is resistant to antibiotics.
Metronidazole will not treat a viral infection such as the common cold or flu.
To be sure metronidazole is not causing harmful effects, your blood may need
to be tested often. Your liver function may also need to be tested. Visit your
doctor regularly.
This medication can cause unusual results with certain medical tests. Tell any
doctor who treats you that you are using metronidazole.
Store metronidazole at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is
almost time for your next scheduled dose. Do not take extra medicine to make
up the missed dose.

What happens if I overdose?

Seek emergency medical attention.
Overdose symptoms may include nausea, vomiting, dizziness, loss of balance
or coordination, numbness and tingling, or seizures (convulsions).

What should I avoid?

Do not drink alcohol while you are taking metronidazole and for at least 3 days
after you stop taking it. You may have unpleasant side effects such as fast

heartbeats, warmth or redness under your skin, tingly feeling, nausea, and
vomiting.
Check the labels of any medicines or food products you use to make sure they
do not contain alcohol.
Antibiotic medicines can cause diarrhea, which may be a sign of a new
infection. If you have diarrhea that is watery or bloody, stop taking
metronidazole and call your doctor. Do not use anti-diarrhea medicine unless
your doctor tells you to.

Metronidazole side effects

Get emergency medical help if you have any of these signs of an allergic
reaction to metronidazole: hives; difficulty breathing; swelling of your face, lips,
tongue, or throat. Call your doctor at once if you have any of these serious side
effects:

numbness or tingling in your hands or feet;

white patches or sores inside your mouth or on your lips;
pain or burning when you urinate;
diarrhea that is watery or bloody;
vision problems, pain behind your eyes;
trouble concentrating, slurred speech, mood or behavior changes, tremors,
muscle twitching, seizure (convulsions);
fever, chills, muscle pain, confusion, headache, sore throat, neck stiffness,
increased sensitivity to light, drowsiness, nausea and vomiting; or
severe skin reaction -- fever, sore throat, swelling in your face or tongue,
burning in your eyes, skin pain, followed by a red or purple skin rash that
spreads (especially in the face or upper body) and causes blistering and
peeling.
Less serious metronidazole side effects may include:

stomach pain, diarrhea;

dizziness, loss of balance;
vaginal itching or discharge;
dry mouth or unpleasant metallic taste;
cough, sneezing, runny or stuffy nose; or
swollen or sore tongue.
This is not a complete list of side effects and others may occur. Call your doctor
for medical advice about side effects.

What other drugs will affect metronidazole?

Tell your doctor about all other medicines you use, especially:

cimetidine (Tagamet);

seizure medication such as phenytoin (Dilantin) or phenobarbital (Luminal,

Solfoton);
a blood thinner such as warfarin (Coumadin, Jantoven);
lithium (Lithobid, Eskalith, others); or
disulfiram (Antabuse).
This list is not complete and other drugs may interact with metronidazole. Tell
your doctor about all medications you use. This includes prescription, over-thecounter, vitamin, and herbal products. Do not start a new medication without
telling your doctor.