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2.
3.
4.
5.
Ability to molt
Takes about 2 days to reach reproductive maturity
Takes 4 days to reach reproductive maturity
Start of visible segmentation at ~2.5 days
Time of hatching or birth similar to xenopus
a. C. elegans
b. zebrafish
drossophila
xenopus
a. Chick
b. Mouse
a. Oogenesis
b. Cleavage
a. Gastrulation
b. Neurulation
a. Nieuwkoop centre
b. Spemanns
organzer
pole
a. Epidermis
formation
b. Brain formation
a. Wnt canonical
pathway
b. Wnt planar polarity
pathway
Sequencing:
Oogonium maturation into primary oocyte
42. Expression and association of VegT and Veg1 within the Balbiani body
43. Cdc25 phosphorylation
44. Activation of MPF
45. Release of progesterone from ovarian follicle cells
46. c-Mos activation
Fertilization
47. secondary oocytes arrested in metaphase II
48. release of second polar body
49. rise in intracellular Ca+
50. secondary oocyte fertilized by sperm
51. destruction of c-mos nd Cdk2 complex
Cleavage
52. transcription of zygotic genome commence
53. cytoplasmic rearrangement
54. accumulation of beta catenin in the region of blastoporal lip
55. secretion of dorsalizing factors
56. formation Spemann organizer
57.
a.
b.
c.
d.
e.
dorsalizing factor
ventralizing factor
c. dorsal mesoderm
ventral mesoderm
ectoderm
58. noggin
59. chordin
60. goosecoid
61. BMP4
62. BMP4
63. vegT
64. vg1
65. xnr1
66. siamois
67. not
a. Endoderm
b. Neural plate formation region of
the brain
c. Primordial germ cells
d. Highly expressed in gut tissues
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
vent1
vent2
sox2
Cat2
N-CAM
Krox20
pdx1
cdx
brachyury
mix1