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Quiz 1

The lowest oxidation number for S is in:


a. CaSo4
b. H2S
c. H2SO3
d. H2SO4
If a single strand protein has independent catalytic and regulatory sites, they can be called
a. Domains
b. Motifs
c. conformers
d. helixes
Diffusion controlled limit (in 1 1 ) is about:
a. 108
b. 106
c. 107
d. 105
The polypeptide with the greatest tendency to form helices is one that has the AA:
a. Gly
b. Ala
c. Arg
d. Asp
For an enzyme classified as an oxidoreductase the most likely cofactor is
a. ATP
b. ADP
c. NAD+
d. AMP
Conversion of pyruvate to lactate in an exercising muscle is done to produce more
a. NAD+
b. NADH
c. Glucose
d. Ethanol
The most abundant protein in humans is
a. Myosin
b. Actin
c. Collagen
d. Dentin
At the p2 of Gpy the two species present at equal concentrations are
a. +NH3CH2COOH and NH2CH2COOb. +NH3CH2COOH and +NH3CH2COOc. +NH3CH2COO- and NH2CH2COOd. +NH3CH2COO- and NH2CH2COOH
The Zwitterionic form of an amino acid has the
a. Amino charged only
b. Carboxy charged only
c. Amino and carboxy charged
d. Amino and carboxy uncharged
The amino acid with the largest absoption at 270 nm is
a. Phe
b. Tyr
c. Trp
d. Arg
An example of a negatively charged amino acids is
a. Arg
b. Asp
c. Gly
d. Ser
A nonpolar amino acid that contains a cyclic structure is
a. Pro
b. Leu
c. Met
d. Val

The so-called branched amino acids belong to the group


a. Nonpolar aliphatic
b. Aromatic
c. Polar uncharged
d. Positively charged
An example of a polar uncharged amino acid is
a. Cys
b. Ala
c. Met
d. Glu
The number of oxygens in the functional group anhydride is
a. 1
b. 2
c. 3
d. 4
The only element that is not classified as a trace element is
a. V
b. Cr
c. Zn
d. Cd
The amino acid common in turns is
a. Pro
b. His
c. Lys
d. Met
Vitamin C is an essential substance for posttranslational modification of the protein
a. Collagen
b. NADH
c. Dentin
d. Actin
The number of nitrogens in the functional group guandinium is
a. 1
b. 2
c. 3
d. 4

Quiz 2
The cofactor used in the formation os glucose 6-phosphate from glucose is
a. Ca
b. Mg
c. K
d. Zn
The cofactor used by pyruvate kinase is
a. Ca
b. Mg
c. K
d. Zn
An apoenzyme is an enzyme that lacks the
a. NADH
b. Cofactor
c. Holoenzyme
d. Prosthetic group
Coenzyme A contains in its molecule a unit of
a. Biotin
b. Panthothenic acid
c. Vit. B2
d. Vit. B1
In order to calculate Vo the following two parameters must be used
a. [P] and time
b. Vo and [S]
c. Velocity and time
d. [P] and velocity
The most precise way to calculate Km is to plot
a. [P] and time
b. Vo and [S]
c. 1/Vo and 1/[S]
d. 1/Vo and 1/P
The Kms for ATP, glucose, lactose, and bicarbonate are .4, .05, 4.0 and 26.0 respectively. The substrate with the most affinity for
the enzyme is:
a. ATP
b. Glucose
c. Lactose
d. bicarbonate
In the derivation of the Michaelis-Menten equation, the assumption is that
a. k2 is rate limiting and all processes are at equilibrium
b. is at a steady rate and k2 is fast
c. E is saturated and k2 is rate liiting
d. Is at a steady rate and k3 is fast
The DNA form(s) that contain the glycosyl bond conformation anti and C-2 endo (are)
a. A
b. B
c. Z
d. B and Z
Vitamin B2 is part of
a. AcCoA
b. NADH
c. FAD
d. PEP
Nucleotides strongly absorb UV light characteristically at around (nm)
a. 200
b. 280
c. 260
d. 240

In glycoproteins, the anomeric section attaches to the residue


a. Pro
b. Ser
c. Met
d. Val
Which statement could be true for humans
a. A homopolymer energy source has -glucose units and is non-reducing
b. A heteropolymer energy source has -glucose units and is non-reducing
c. A heteropolymer energy source has -glucose units and is non-reducing
d. A homopolymer energy source has -glucose units and is reducing
The largest proportion of glucose present in a solution of -D-glucose is
a. -D-glucopyranose
b. -D-fructofuranose
c. - D-glucopyranose
d. - D-fructofuranose
If one unit of acetone reacts completely with methanol, the units of methanol used is
a. 1
b. 2
c. 3
d. 4
The number of isometric structures that a linear 6-carbon D-aldose can have is
a. 4
b. 6
c. 8
d. 10
An amino acid that disordered proteins normally contain in high amounts is
a. Glu
b. Ala
c. Ser
d. Trp
In myoglobin, the O2 molecule is held in place with the help of the amino acid
a. Pro
b. Lys
c. His
d. Met
The heme in myoglobin is classified as a
a. Cofactor
b. Apoenzyme
c. Prosthetic group
d. Holo enzyme
Which statement is true of myoglobin?
a. The five pyrrole rings of heme coordinate to Fe3+
b. The four pyrrole units of heme covalently bind to Fe2+
c. The four pyrrole unites of heme coordinate to Fe
d. The flat pyrrole units of heme coordinate to Fe2+
The substance that has the lowest Kd when mixed with biotin is
a. Insulin
b. Avidin
c. AcCoA
d. Neomycin

Quiz 3
The number of double bonds in arachidonic acid is:
a. 2
b. 3
c. 4
d. 5
A fatty acid that is considered essential is
a. Oleic
b. Palmitoleic
c. Linolenic
d. Stearic
The acid with the lowest melting point is
a. Oleic
b. Palmitoleic
c. Linolenic
d. Stearic
A recombinant vector is a
a. Plasmid
b. Virus
c. Modified plasmid
d. Host cell
Sticky ends are
a. Palindromic
b. Isometric
c. Blunt
d. Telomeric
16:1(12 ) corresponds to an omega
a. 1
b. 2
c. 3
d. 4
The number of fatty acids in a sphingolipid is
a. 1
b. 2
c. 3
d. 4
BAC stands for
a. Bacterial amorphous chromatids
b. Banded amorphous chromosomes
c. Bacterial artificial chromatids
d. Bacterial artificial chromasomes
The number of fatty acid units in storage lipids is
a. 1
b. 2
c. 3
d. 4
Plasmalogens are present in large amounts in the
a. Heart
b. Liver
c. Intestine
d. Pancreas
Degradation of phospholipids occurs preferentially in
a. Golgi
b. ER
c. Cytosol
d. Lysosome
Leukotrienes derive from

a. Phospholipids
b. Arachidonate
c. Linoleate
d. Isoprene
At normal human temperature, the membrane bilayer is

a. Ordered with receptors highly active


b. Ordered with receptors poorly active
c. Disordered with receptors highly active
d. Disordered with receptors poorly active
Lateral diffusion is
a. Slow and needs catalysis
b. Fast and needs catalysis
c. Fast and does not need catalysis
d. Slow and does not need catalysis
The main transporter of glucose in the muscle is
a. Glut 1
b. Glut 2
c. Glut 3
d. Glut 4
The chloride-bicarbonate transporter is a
a. Uniport
b. Symport
c. Antiport
d. Channel
The number of critical cytosolic domains in a Na+K+ATPase is
a. 2
b. 3
c. 4
d. 5
The number of transporters required to move glucose fro the intestinal lumen into the capillary blood is
a. 1
b. 2
c. 3
d. 4
In a normal cell the Na+K+ATPaes moves Na+:K+ in a ratio
a. 3 in, 2 out
b. 2 in, 2 out
c. 2 out, 3 in
d. 3 out, 2 in
In a normal cell, simple diffusion occurs with
a. Polar compounds down concentration gradient
b. Nonpolar compounds down concentration gradient
c. Nonpolar compounds down electrochemical gradient
d. Nonpolar compounds against concentration gradient

Quiz 4
When cAMP is cleaved by phosphodiesterase the product AMP has a
a. 2-PO4
b. 3-PO4
c. 4-PO4
d. 5-PO4
The number of coordinated bonds Mg2+ forms with rubisco, substrates and amino acids is
a. 4
b. 6
c. 8
d. 9
The number of stages in which ATP is used in the Calvin cycle is
a. 1
b. 2
c. 3
d. 4
The amino acids involved in catalysis by rubisco are
a) Glu, Lys, Cys
b) Lys, Asp, Glu
c) His, Lys, Glu
d) His, Cys, Lys
The Calvin cycle takes place in the
a. Stroma
b. Cytosol
c. Thylakoid
d. Endosome
The bond formed between -glucose and fructose 6-PO4 to form sucrose-6-PO4 is
a. 1-2
b. 1-3
c. 1-4
d. 1-5
The material produced in the glyoxylate cycle that is further used in the Krebs cycle is
a. Citrate
b. Malate
c. Succinate
d. Oxaloacetate
Protein Kinase C is activated by
a. 4 units of cAMP
b. Diacylglycerol and Ca2+
c. IP3 and Ca2+
d. GTP and adenylyl cyclase
When oxaloacetate gets decarboxylated by carboxykinase/GTP the product is
a. Pyruvate
b. PEP
c. Lactate
d. Acetate
Glycerol 3-phosphate dehydrogenase/NAD+ converts glycerol 3=PO4 into
a. Glycerol 2-PO4
b. Glygerol
c. Glyceraldehyde
d. Dihydroxyacetone PO4

The product of the action of phosphofructokinase-1 in glycolysis is


a. Fructose 6-phosphate
b. Fructose 1,6 biphosphate
c. Fructose 1,6 bisphosphate
d. Dihydroxyacetone phosphate + glyceraldehyde 3-phosphate
MATCHING: Match the enzyme provided in this list with its product given below. (This is seriously how he did
matching, basically circle the letter that the correct answer is labeled with.)
a)enolase b)triose phosphate isomerase c)phosphoglycerate mutase d)pyruvate carboxylase
a)actonase b)phosphopentose isomerase c)dihydrolipoyl transacetylase d)aconitase
a)succinate dehydrogenase b)glutathionine reductase c)malate dehydrogrnase d)isocitrate dehydrogenase
a)-ketoglutarate dehydrogenase complex b)citrate synthase c)alcohol dehydrogenase d)succinyl-CoA synthetase
AcCoA
a
b
c
d
PEP
a
b
c
d
Fumarate
a
b
c
d
Succinyl CoA
a
b
c
d
Match the amino acid or cofactor given with the enzyme above that uses it in its active site (list above is still used)
His
a
b
c
d
Mn2+
a
b
c
d
Zn2+
a
b
c
d
Before starch is converted to glucose 6-phosphate the following enzyme must be used
a. Lactase
b. Phosphoglucomutase
c. Enolase
d. Fructokinase
From highest to lowet, the order of energy of hydrolysis is
a. PEP, phosphocreatine, 1,3-bisphosphoglycerate, ATP
b. Phosphocreatine, 1.3-bisphosphoglycerate, ATP, PEP
c. PEP, 1,3-bisphosphoglycerate, phosphocreatine, ATP
d. PEP, 1,3-bisphosphoglycerate, ATP, phosphocreatine
The transporter of electrons between photosystem I and NADP reductase is
a. Plastoquinone
b. Plastocyanin
c. Ferredoxin
d. H2O
The steroid involved in transport of glucose for cellulose synthesis is
a. Ergosterol
b. Lanosterol
c. Cholesterol
d. Sitosterol

Quiz 5
A fatty acid taken from the adipocyte is the result of how many hydrolysis from the original ingested fat
a. 1
b. 2
c. 3
d. 4
The number f hydrogenases required to produce one unit os AcCoA from a fatty acid is
a. 1
b. 2
c. 3
d. 4
A vitamin used as a cofactor in the -oxidation of odd fatty acids is
a. C
b. B1
c. B12
d. B2
-oxidation the produces a -ketoAcCoA is equivalent in the Krebs cycle to the conversion to succinate to
a. Malate
b. Fumarate
c. Citrate
d. Oxaloacetate
The compound the is not a ketone body is
a. Acetone
b. Oxaloacetate
c. Hydroxybutyrate
d. Acetoacetate
When ammonia is oxidized to nitrate by nitrifying bacteria, the amount of electrons lost by nitrogen is
a. 3
b. 5
c. 8
d. 10
The percentage of essential amino acids produced from glycolysis intermediates is
a) 47%
b) 58%
c) 67%
d) 75%
The function of bile salts in the intestine is to
a) Hydrolyze ingested fats
b) Help forming the chylomicron
c) Emulsify ingested fats
d) Emulsify fatty acids and glycerol
A precursor for the synthesis of epinephrine is
a) Pyruvate
b) Oxaloacetate
c) 3-phosphoglycerate
d) -ketoglutarate
An amino acid that is not part of glutathionine is
a) GLu
b) Gly
c) Cys
d) Ala

The percentage of positively charged amino acids produced from glycolysis intermediates is
a) 67%
b) 33%
c) 25%
d) 75%
An enyme involved in the formation of the catechol in catecholamines from Tyr is a
a) Hydroxylase
b) Aminotransferase
c) Decarboxylase
d) Reductase
One of the substances that is heavily involved in regulation of nucleotide synthesis is
a) AMP
b) ADP
c) ATP
d) IMP
A cofactor involved with the transfer of amino groups is
a) PEP
b) PLP
c) ATP
d) Fe2+
Removal of the ammonia from glutathionine is performed in liver mitochondria by
a) Glutamine synthase
b) Glutamine synthetase
c) Glutamine decarboxylase
d) Glutaminase
One of the most abundant substances in the animal body is
a) Glutamate
b) Glutathionine
c) ATP
d) Fructose 1,6-phosphate
The number of ATP units used in the synthesis of carbamoyl phosphate is
a) 1
b) 2
c) 3
d) 4
When arginosuccinate is converted to arginine, the second product of the reaction is
a) Glutamate
b) Fumarate
c) Succinate
d) Oxaloacetate
When arginine is converted to ornithine, the second product of the reaction is
a) Urea
b) Citrulline
c) Fumarate
d) CO2
When arginine is converted with O2 directly into citrulline the second product of the reaction is
a) HCO3b) NO
c) CO
d) CO2

When xanthine is converted to uric acid by xanthine oxidase a byproduct of the reaction is
a) H2O2
b) NH4+
c) H2O
d) CO2
The number of amino acids used to build the purine ring is
a) 1
b) 2
c) 3
d) 4

Quiz 6
In order to organize the looping of chromosome segments one needs
a) Cohesins and condensins
b) Cohesins and ATP
c) Condensins and ATP
d) Condensins and NADH
An example of an SMC protein is
a) Nucleosome
b) Condensing
c) Histone
d) Chromatin
A solenoidal is a
A) Twisted thread
B) Right handed supercoil
C) Left handed supercoil
D) Positive supercoil
The octamer of histones is formed by
a) H1, H2A, H2B, H3
b) H1, H2A, H2B, H4
c) H2A, H2B, H3, H4
d) H1, H2A, H3, H4
The histone with the highest molecular mass is
a) H1
b) H2B
c) H3
d) H4
Histones are rich in amino acids that are
a) Negatively charged
b) Aromatic
c) Non-polar
d) Positively charged
When topoisomerase I cleaves, DNA produces
a) Two 5 phosphorylations
b) Two 3phosphorylations
c) One 3 phosphorylation
d) One 5 phosphorylation
The nucleophile in topoisomerase I responsible for the attack on DNA is
a) Ser
b) Cys
c) Thr
d) Tyr
An enzyme that most likely is not present in the mitochondrial complex is
a) Hexokinase
b) Aconitase
c) Fumarase
d) Enoyl CoA hydratase
A transporter that should not be represent in the inner mitochondrial membrane is
a) ADP-ATP translocase
b) Glutamate-aspartate
c) Glut-2
d) Carnitine

Succinic-oxalic-malonic-glutaric by number of carbons is equivalent to


a) 2-3-4-5
b) 4-2-3-5
c) 4-3-2-5
d) 3-5-2-4
One characteristic of FAS I is that the incoming acetyl and malonyl groups are held as
a) Thioesters
b) Thioethers
c) Thioether one and thioester the other
d) Thioester one and regular ester the other
The number of Co2 released when one stearic acid is made by FAS I is
a) 6
b) 7
c) 8
d) 9
The number of NADP+ produced in the synthesis of one lauric acid by FAS I is
a) 6
b) 8
c) 10
d) 12
The respiratory chain complex with the highest molecular mass is complex
a) I
b) II
c) III
d) IV
The number of protons pumped/NADH by the combined complexes I, II, and IV is
a) 2
b) 4
c) 6
d) 8
The role of glutathionine peroxidase is to
a) Oxidize H2O2
b) Reduce H2O2
c) Oxidize O2d) Oxidize glutathione disulfide
When NADH is transferred into the matrix, -ketoglutarate moves from
a) Matrix to intermembrane space
b) Intermembrane space to matrix
c) Both sides but starts in the matrix
d) Both but starts in the intermembrane space
Leptin is preferentially associated with
a) Adipocyte
b) Perilipin
c) G protein
d) PKA
The number of hormone classes derived from cholesterol is
a) 1
b) 2
c) 3
d) 4

Answer Key
Quiz 1: BAABCACCCCBAAACDAAAC
Quiz 2: BCDBBCBCDCCBBCBCACCDB
Quiz 3: CCDCADADCADBCCDCBBDB
Quiz 4: DBBBAACBBDCCAAABDCBCCD
Quiz 5: CBCDBCCCCDBAABDABBABAC
Quiz 6: CBCCADDDACBACCACBAAB