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Schizophrenia Medications:
First generations medications cause limbic and motor affects; not
use very often
Extrapyramidal side effects (EPS): dystonia, akathsia and
psudeoparkinsons
Anticholinergic drugs for side effects: trihexyphenidyl (Artane) and
benztropine mesylate (Cogentin)
Tardive Dyskenia is persistent EPS is 10% of patient long after
medication is stopped
Other Side effects include: weight gain, sexual dysfunction,
gynecomastia, drooling, and tardive dyskinesia, (Halter 219)
Suffix Chlorpromaize (thorazine) and Haperdoil (Haldol)
Second generations are the primary treatment and cause less EPS
risperidone (Risperdal), olanzapine (Zyprexa), quetiapine (Seroquel),
and ziprasidone
clozapine (Clozaril) is the most effective but due to angroulocytosis
WBC is needed every six months
common side effects is usually metabolic syndromewhich includes
weight gain, dyslipidemia, and altered glucose metabolism thought to
be due to increased insulin resistance
The only third generation Arirprizole (Amblify) and causes little
side effects
Bipolar Medications:
Advanced toxicity
o Confusion, muscle hyperirritability, coarse hand tremors, EKG changes
and sedation
Severe toxicity
o Ataxia, seizures, stupor, severe hypotension, blurred vision,
convulsions DEATH
Anticonvulsants
valproate (Depakote), carbamazepine (Tegretol), and lamotrigine
(Lamictal)
monitor liver and platelet count for valproate (Depakote) AND
carbamazepine (Tegretol)
a rare but very serious demagogical rash may appear with lamotrigine
Sedatives (anxiolytic)
Clonazepam (Klonopin) and lorazepam (Ativan) are antianxiety
(anxiolytic)
Used with acute mania, should not be used in patient with substance
abuse history
Serotonin Selective Reuptake Inhibitors
First line of treatment for major depression
Some SSRIs activate and others sedate; choice depends on patient
symptoms
Risk of lethal overdose minimized with SSRIs
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Tricyclic Antidepressants
Antianxiety Medications:
Selective Serotonin Reuptake Inhibitors (Antidepressants)
https://pageburstls.elsevier.com/books/978-1-4557-53581/id/B9781455753581000243_t0130