Tables of included studies and results for the Clinical Guideline Update on "Immune thrombocytop

enia: An
evidence based practice guideline developed by the American Society of Hematology"
In the process of the guideline development it was decided to reduce the published volume of guidelines by producing an on-line supplement. In
this supplement there are details about the studies that have gone into the final guideline. This will hopefully help interested parties determine
how the guideline writing group came to their conclusions. The tables are not exhaustive and should not replace careful appraisal of individual
papers. Each tables format is dependent on the question asked and information deemed important by the individual author who produced the
table.

Author
Study type
Eligibility
Number o
Results
Notes
year
f
Not
all papers
referenced in this on-line supplement
appear in the final published guideline. Papers not directly contributing to
Calpin
Retrospective Acute ITP with typic
332
No cases of acute leukemia; 1 patie Addresses patients with initial diagnosis of ITP
recommendation
were often not referenced
1998
review or suggestion
al
nt within the text.
rather
features, 6 monthsmarrow aplasia; 95% confidence th than working backwards from patients with leu

Section 1: ITP in children

Case 1: Newly Diagnosed ITP in Children
1.1 Diagnosis of ITP
Question: Are there additional tests that can help confirm the diagnosis of ITP in this patient?
Table S1.1.1 Are there additional tests that can help confirm the diagnosis of ITP in this patient? Bone marrow examination.

Table S1.1.1 References

Calpin C, Dick P, Poon A, Feldman W. Is bone marrow aspiration needed in acute childhood idiopathic thrombocytopenic purpura to rule out
leukemia? Arch Ped Adol Med. 1998;152:345-347.

Author
year
Study