M0:

Mnimame
nte
Diferencia
da

Incidencia

3-5%

M1:
Sin
Maduraci
n

10-20%
(46 aos)

M2:
Con
Madurac
in
30-45%
20% < 25
aos
40%

M3:
Promielocit
ica
hipergranul
ar

M3 V:
Promieloci
tica
microgran
ular

5-8%

1-1.6%
infrecuente

M4:
Mielonocit
ica

15-25%

M5a:
Monoblast
ica

5-8%
25% < 25
aos

M5b:
Monocitic
a

M6a:
Eritroleuce
mia

M6b:
Eritroleuce
mia pura

M7:
Megacarioci
tica

3-6%

5-6%

Rara

3-5%

60

aos

Blastos de
clulas no
eritroides

90%

90%

80%
Tipo I:
>5%

20%
t(8:21)

Eritoblasto
s

No
Relevante

Component
e mieloide

No
Relevante

Component
e
monoctico
Bastones
de Auer%
de casos
MPO
CAE
ANAE/ANBE

No
Relevante

10%

< 50%

80%

80%

80%

20%

<80%
Blastos o
Blast +
Promonoci
to

Solo
promielocito
s
Tipo I: <5%

Solo
promielocito
s
Tipo I: <5%

< 80%
Displasia
eosinofilica

Blastos o
Blast +
Promonocit
o

< 50%

< 50%

< 50%

No
Relevante

No
Relevante

>10%

>10%

< 20%

< 20%

20%

20%

No
importantes

50%

> 80%

No
Relevante

Variable

Variable

No
Relevante

Variable

Variable

No
Relevante

10%

20%

< 10%

< 20%

< 20%

< 20%

20 79%
monoctic
os
maduros

0%

50%

60 70%
Clulas
de
Faggot
(Rara)

90 -95%
Clulas de
Faggot

90 -95%
Clulas de
Faggot

60%

Raros

30%

Ocasionale
s

0%

0%

<3% blast
+
-

>3%
blast +
-/+
-

> 10%

++

++

-/+

30% +

+/-

++
-

++
-

++
-

-/+
+

++

-/+
++

-/+
-

-/+
-/(+ANAE)

-/+ granular
grueso

+ granular
grueso o
difuso en
Eribl.

++granular
grueso en
Eribl.

+difuso/-

+
-/+ dbil

+
-/+

+/-

-/+
-

No
Relevante

PAS

-/+ difuso

-/+
difuso

HLA-DR
MPO

+
-

+/+/-

+/++

80%

+ difuso

+ difuso

-/+ difuso

-/+ granular
grueso

-/+
++

-/+
++

+
+

+
-/+ dbil

80%

CD
CD
CD
CD

34
13
38
45

+
+/+
-/+ dbil

+/+/-/+ dbil

++t(8;21)/-

-/+ t(15;17)

-/+ t(15;17)

+
-/+
+
t(8:21)/-

++
-/+ dbil

++
++

-/+
++
++

-/+
+
+

-/+
+
+

+
+
+

-/+
+/+

+/+/-/+

CD 56

CD 117

+/-

-/+

-/+

+/-(- con
11q23)

+/-

-/+ +con
CD34

+/-(- con
11q23)
-/+ +con
CD34

CD 15

+/-

CD 65
CD 2
CD 7

+dbil/+dbil/-

+/-/+dbil

+
-

-/+

-/+

+Coexp.CD2/-

+Coexp.CD2/-

+
-

+
-/+ dbil

+
-

+/-

-/+
-

+/+aberrante

-/+ +con
CD34

-/+ +con
CD34

CD 19

+dbil/-

+coexp
t(8;21)

Tdt

+dbil/-

+Coexp
CD9/-

+Coexp
CD9/-

+/-

+/-

+/-

+/-

-/+

-/+

++

Glicoforina
A
Hemoglobi
na A
Lisozima
CD41a,61,4
2