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Manufacturing
redesign that kept the look of the original
shape but took some of the volume out of
the band of the tablet, the manufacturer
was able to reduce all of their efficiency
issues and still present a tablet that was
appealing to consumers.
Clearly, changes to a tablet shape
can reduce costs during production. In
addition to reducing excess ejection force,
adjusting the shape can reduce issues
such as heat and friction during tableting
two things that can cause considerable
problems for a tablet press. Reducing
these issues will significantly reduce parts
wear, tooling and other operating costs
all of which add up quickly.
What Kind of Design Changes can Help
Increase Efficiency?
One of the simple tablet shape changes
that can be made and will bring positive
results is to consider switching from
a bevel edge to a radius edge when
producing uncoated flat bevelled tablets.
This is an improvement that doesnt affect
the overall tablet shape, but can greatly
help to ensure smooth tablet production.
Understandably, companies do what
they can to limit expenditures throughout
the development process. A common
and ill-advised practice is for companies
to attempt to replicate or duplicate an
existing tablet with an inherently weak or
problematic design. This often happens
when companies reproduce designs
already in their portfolio.
One of the oldest tablet designs, the
flat-face (FF) design, has been commonly
used to produce tablets. As commercial
tablet manufacturing took off, the industry
found it needed to rectify edge attrition in
flat-faced tablets. Edge attrition occurred
as the flat-face tool entered into the
compression cycle and pushed powder
to the outside perimeter of the punch tip
and towards the die wall, which in turn
extruded through the punch and die
clearance.
Increase Strength by Increasing Bevel to Flat Radius
R.015
R.060
R.030
COLOR KEY
Strength
Weakness
Figure 4
Manufacturing