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Temporalarterybiopsy:impactontheclinicalmanagementofpatients.PubMedNCBI
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IndianJSurg.2008Apr70(2):736.doi:10.1007/s1226200800197.Epub2008May21.
Temporalarterybiopsy:impactontheclinicalmanagementofpatients.
SintlerM1,GarnhamA,MahmoodA,RittooD,KhairaHS,VohraRK.
Authorinformation
1
DepartmentofVascularSurgery,2ndFloor,SBlock,UniversityHospitalBirminghamNHSTrust,Selly
OakHospital,Birmingham,B296JDUK.
Abstract
OBJECTIVES: Temporalarterybiopsy(TAB)isrequestedinanattempttoconfirmthediagnosisof
temporalarteritis(TA).PatientssymptomsandsignsarehighlyvariableandTAisoftenfocaland
potentiallymissedinasmallbiopsy.ThestudyaimedtodetermineifTABhelpsinthemanagementof
patientswithsuspectedTA.
METHODS: Thecaserecordsofsixtysixconsecutivepatientswhohadundergonetemporalartery
biopsywererecalledandexaminedforpresentingsymptoms,management,therapy,resultsand
outcome.
RESULTS: Therewere23menand43womenwithameanageof70.2and71.1yearsrespectively.
Presentingsymptomsvariedwithunilateralheadachein53,scalptendernessin16,muscleweaknessin
10,visualdisturbancein16,jawclaudicationin5andperiorbitalpainin1patient.Thetemporalartery
wastenderin21patientsandthickenedin4patients.Thirtyeightpatientswerecommencedonsteroids
priortobiopsyand6morebeforethehistologybecameavailable.Only8%ofbiopsieswerepositivefor
TA.Ofthepatientsstartedonsteroidswithanegativebiopsy,thesteroidswerecontinuedin26and
stoppedin9.Inthepatientsnotputonsteroids[22],biopsywaspositivein2theywerecommencedon
steroids.Therefore,thehistologicaldiagnosisresultedinachangeinpatientmanagementinonly18%
ofpatients.
CONCLUSION: TheresultsofTABdonotappeartoaffecttheclinicalmanagementofmostpatientswith
suspectedtemporalarteritis.Wemustthereforequestiontheroutineuseofthisinvasiveinvestigation.
PMID:23133025 PMCID:PMC3452393 DOI:10.1007/s1226200800197
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