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Infertility / andrology / endocrinology EMQ-1

10 random questions for EMQ Test


Options for Questions 1-1
A

Prolactinoma

Pre-mature ovarian failure

Turners syndrome

Ovarian hyper-stimulation syndrome

Polycystic ovary syndrome

Hypothyroidism

Cushings syndrome

Congenital adrenal hyperplasia

Hypothalamic amenorrhoea

Hyperthyroidism

Androgen insensitivity syndrome

Pure gonadal dysgenesis

Instrunctions:For each of the case histories described below, choose the single most likely
cause of menstrual abnormalities from the above list. Each option may be used once, more than
once, or not at all.
Explanation

Question 1

A 36 year old woman and her 40 year old partner have been referred to
the fertility clinic because of a failure to conceive after 18 months of
unprotected intercourse. The semen analysis is normal. The woman
has irregular periods every 3-6 months but no other symptoms and her
E
BMI is 27. The woman?s results are as follows: FSH (day 3) =
6mIU/ml, LH (day 3) = 8mIU/ml, prolactin = 110 ng/ml, progesterone
(day 21) = 3ng/ml, testosterone = 4.0pg/ml, DHEA, DHEA-sulphate
and thyroid function tests were normal.

Options for Questions 2-2


A

Prolactinoma

Pre-mature ovarian failure

Turners syndrome

Ovarian hyper-stimulation syndrome

Polycystic ovary syndrome

Hypothyroidism

Cushings syndrome

Congenital adrenal hyperplasia

Hypothalamic amenorrhoea

Hyperthyroidism

Androgen insensitivity syndrome

Pure gonadal dysgenesis

Instrunctions:For each of the case histories described below, choose the single most likely
cause of menstrual abnormalities from the above list. Each option may be used once, more than
once, or not at all.
Explanation

Question 2

A 35 year old woman and her 40 year old partner have been referred to
the fertility clinic because of a failure to conceive after 3 years of
unprotected intercourse. The semen analysis is normal. The woman
B
has irregular periods every 3-6 months but no other symptoms and her
BMI is 27. The woman?s results are as follows: FSH (day 3) =
20mIU/ml, LH (day 3) = 8mIU/ml, prolactin = 110 ng/ml,

Infertility / andrology / endocrinology EMQ-2

progesterone (day 21) = 1.5ng/ml, testosterone = 2.0pg/ml, DHEA,


DHEA-sulphate and thyroid function tests were normal.

Options for Questions 3-3


A

Prolactinoma

Pre-mature ovarian failure

Asherman?s syndrome

Ovarian hyper-stimulation syndrome

Polycystic ovary syndrome

Hypothyroidism

Androgen secreting tumour

Cervical stenosis

Hypothalamic amenorrhoea

Hyperthyroidism

Androgen insensitivity syndrome

Pure gonadal dysgenesis

Instrunctions:For each of the case histories described below, choose the single most likely
cause of amenorrhoea from the above list. Each option may be used once, more than once, or not
at all.
Explanation

Question 3

A 25 year old woman and her 24 year old partner attend the fertility
clinic because of a failure to conceive after 2 years of unprotected
intercourse. The man?s semen analysis is normal. The woman
complains of absent menses over the last 2 years. On examination, her
B
height is 1.6m and BMI is 22 but there are no abnormalities. FSH =
35mIU/ml, LH = 12mIU/ml, prolactin = 22ng/ml, testosterone =
1.5pg/ml and thyroid function tests and pelvic ultrasound scan are
normal. Karyotype shows 46XX / 45XO.

Options for Questions 4-5


A

In-vitro fertilisation

Intra-uterine insemination

Laparoscopy and dye test

Laparoscopic ovarian drilling

Clomephene citrate

Gonadotrophin induction of ovulation

Metformin

Carbegolline

Oocyte donation

Weight reduction

Weight gain

Measure serum androgen concentrations

Instrunctions:For each of the case histories described below, choose the single most appropriate
initial management from the above list. Each option may be used once, more than once, or not at
all.
Explanation
Question 4

A 24 year old woman with her 35 year old partner has been referred to
J
the infertility clinic because of 2 years of primary infertility. The

Infertility / andrology / endocrinology EMQ-3

woman has an irregular menstrual cycle every 2-4 months and her
partner's semen analysis shows a volume of 2.5ml, concentration of
30,million/ml and motility of 65%. The woman?s BMI is 34 and there
is no significant past medical history. Investigations have confirmed a
diagnosis of polycystic ovary syndrome.

Question 5

A 35 year old woman with her 45 year old partner has been referred to
the infertility clinic because of 2 years of primary infertility. The
woman has an irregular menstrual cycle every 2-4 months and her
partner?s semen analysis shows a volume of 3ml, concentration of
E
30,million/ml and motility of 60%. The woman?s BMI is 24 and there
is no significant past medical history. Investigations have confirmed a
diagnosis of polycystic ovary syndrome.

Options for Questions 6-6


A

In-vitro fertilisation

Intra-uterine insemination

Laparoscopy and dye test

Laparoscopic ovarian drilling

Clomephene citrate

Gonadotrophin induction of ovulation

Metformin

Carbegolline

Oocyte donation

Weight reduction

Weight gain

Measure serum androgen concentrations

Instrunctions:For each of the case histories described below, choose the single most appropriate
initial management from the above list. Each option may be used once, more than once, or not at
all.
Explanation

Question 6

A 34 year old woman with her 35 year old partner has been referred to
the infertility clinic because of 2 years of primary infertility. The
woman has a regular 28 day cycle and her periods are heavy with
severe dysmenorrhoea. She also complains of deep dyspareunia and
C
intermittent lower abdominal and pelvic pain. Her BMI is 27.
Investigations have shown normal LH, FHS, Thyroid function tests,
prolactin and day 21 progesterone concentration confirms ovulatory
cycles. Her partner?s semen analysis is normal.

Options for Questions 7-7


A

In-vitro fertilisation

Intra-uterine insemination

Laparoscopy and dye test

Laparoscopic ovarian drilling

Clomephene citrate

Gonadotrophin induction of ovulation

Metformin

Carbegolline

Hystero-salpingogram

Weight reduction

Infertility / andrology / endocrinology EMQ-4

Weight gain

Measure serum androgen concentrations

Instrunctions:For each of the case histories described below, choose the single most appropriate
initial management from the above list. Each option may be used once, more than once, or not at
all.
Explanation

Question 7

A 36 year old woman with her 35 year old partner has been referred to
the infertility clinic because of 2 years of primary infertility. The
woman has a regular and normal 28 day cycle, her BMI is 26 and she
has no other symptoms. Investigations have shown normal LH =
B
7.5mIU/ml, FHS = 17mIU/ml, Thyroid function tests, prolactin and
day 21 progesterone concentration confirms ovulatory cycles. Her
partner?s semen analysis is normal. Hystero-salpingogram confirms
bilateral patent fallopian tubes.

Options for Questions 8-9


A

FSH & LH concentration on days 2-5

Serum prolactin

Day 21 progesterone

Random serum oestradiol

Neonatal 17-hydroxy-progesterone
concentration

Pelvic ultrasound scan

Serum androgen concentrations

Progesterone challenge test

Dexamethasone suppression test

MRI scan of abdomen and pelvis

Karyotype

Random serum FSH concentration

Instrunctions:For each of the case histories described below, choose the single most appropriate
investigation from the above list. Each option may be used once, more than once, or not at all.
Explanation

Question 8

An 38 year old woman has just had a forceps delivery and the neonate
has been found to have ambiguous external genitalia. Her medical
records show that she had amniocentesis at 18 weeks gestation
E
because of a high risk of Down?s syndrome on serum screening and
the fetus was found to have a 46XX karyotype.

Question 9

A 20 year old woman has been referred to the gynaecology clinic


because she has not had any menstrual periods for over 2 years. She
has no other symptoms. On examination, her height is 1.6m and BMI K
is 22. There was slight webbing of the neck, widely spaced nipples and
a wide carrying angle.

Options for Questions 10-10


A

Cancel IVF cycle

Freeze embryos

Infertility / andrology / endocrinology EMQ-5

Admit for iv fluids and


thromboprophylaxis

Termination of pregnancy

Transfer to ITU

Fluid restriction

Drain pleural effusion

Drain ascites

Drain ovarian cysts

Proceed with embryo replacement

Avoid unprotected sexual intercourse

Diuretics

Instrunctions:For each of the case histories described below, choose the single most appropriate
management from the above list. Each option may be used once, more than once, or not at all.
Explanation
A 35 year old woman with PCOS is undergoing IVF treatment. She
attends for embryo replacement 6 days after HCG administration and
complains of abdominal distension and pain with nausea and vomiting
B
Question 10
2-3 times per day over the previous 48h. Clinical examination showed
a mildly distended abdomen and ultrasound scan confirmed bilateral
ovarian enlargement 8-10cm. All her blood tests were normal.
10 random questions for EMQ Test
Options for Questions 1-1
A

Serial beta-HCG assay

Laparoscopy

Repeat trans-vaginal scan in 24h

Repeat trans-vaginal scan in 7 days

Counsel and discharge

Offer surgical evacuation of products of


conception

Offer medical treatment with


methotrexate

Laparotomy

Serum progesterone assay

Serum AFP assay

Refer to molar pregnancy centre

Refer to other specialty

Instrunctions:Instructions: For each patient described below choose the single most appropriate
initial management option from the list. Each option may be used once, more than once, or not at
all.
Explanation

Question 1

An asymptomatic 30 year old woman with a previous ectopic


pregnancy presents at 6 weeks amenorrhoea for trans-vaginal scan to
exclude a repeat ectopic pregnancy. Her pregnancy test had been
positive 2 weeks earlier. The scan is reported to show a 14mm
B
endometrium with no gestation sac. There is a 4cm cystic structure in
the right adnexum suggestive of an ectopic pregnancy but no free fluid
in the pouch of Douglas

Options for Questions 2-2

Infertility / andrology / endocrinology EMQ-6

Medical evacuation with misoprostol

Medical evacuation with mifepristone +


misoprostol

Suction evacuation without cervical


preparation

Suction evacuation with cervical


preparation

Dilatation and curettage

Medical evacuation with oxytocin


infusion

Medical evacuation with mifepristone +


H
oxytocin infusion

Administer iv oxytocin

Administer im ergometrine

Expedite suction evacuation

Blood transfusion

Administer im carboprost

Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation

Question 2

A healthy 23 year old woman is on the gynaecological ward awaiting


treatment for a complete molar pregnancy at 7 weeks gestation. You
are called to see her because she is bleeding heavily. Pulse = 100/min,
BP = 110/80.

Options for Questions 3-3


A

Chest X-ray

V/Q scan

Lung perfusion scan

Lung ventilation scan

CTPA

Pulmonary angiography

ECG

Lower limb Doppler ultrasound scan

Arterial blood gases

D-dimers

Spirometry

Lower limb venogram

Instrunctions:For each of the scenarios below, select the single most appropriate subsequent
investigation from the above list. Each option may be used once, more than once, or not at all.
Explanation

Question 3

A healthy 32 year old woman presents at 34 weeks gestation with


sudden onset shortness of breadth and pleuritic chest pain. She has a
pulse of 110 / min, BP 120/80 and SO2 = 95% on air. She is
administered a therapeutic dose of low molecular weight heparin.
E
Chest X-ray and lower limb Dopplers are normal. Following
counselling, the woman prefers the investigation that exposes her fetus
to the lowest level of radiation.

Infertility / andrology / endocrinology EMQ-7

Options for Questions 4-4


A

Prolactinoma

Pre-mature ovarian failure

Asherman?s syndrome

Ovarian hyper-stimulation syndrome

Polycystic ovary syndrome

Hypothyroidism

Androgen secreting tumour

Cervical stenosis

Hypothalamic amenorrhoea

Hyperthyroidism

Androgen insensitivity syndrome

Pure gonadal dysgenesis

Instrunctions:For each of the case histories described below, choose the single most likely
cause of amenorrhoea from the above list. Each option may be used once, more than once, or not
at all.
Explanation

Question 4

A 25 year old woman and her 24 year old partner attend the fertility
clinic because of a failure to conceive after 2 years of unprotected
intercourse. The man?s semen analysis is normal. The woman
complains of absent menses over the last 2 years. On examination, her
B
height is 1.6m and BMI is 22 but there are no abnormalities. FSH =
35mIU/ml, LH = 12mIU/ml, prolactin = 22ng/ml, testosterone =
1.5pg/ml and thyroid function tests and pelvic ultrasound scan are
normal. Karyotype shows 46XX / 45XO.

Options for Questions 5-5


A

Prolactinoma

Pre-mature ovarian failure

Asherman?s syndrome

Ovarian hyper-stimulation syndrome

Polycystic ovary syndrome

Hypothyroidism

Androgen secreting tumour

Cervical stenosis

Hypothalamic amenorrhoea

Hyperthyroidism

Androgen insensitivity syndrome

Pure gonadal dysgenesis

Instrunctions:For each of the case histories described below, choose the single most likely
cause of amenorrhoea from the above list. Each option may be used once, more than once, or not
at all.
Explanation

Question 5

An 18 year virgin has been referred to the gynaecology clinic because


she has not started menstruating but she has no other symptoms.
Clinical examination showed that her height was 1.67m with BMI of
23. She had normally formed breasts but no axillary or pubic hair.
There was a 2-3cm mass palpable in each inguinal canal.

Infertility / andrology / endocrinology EMQ-8

Options for Questions 6-6


A

In-vitro fertilisation

Intra-uterine insemination

Laparoscopy and dye test

Laparoscopic ovarian drilling

Clomephene citrate

Gonadotrophin induction of ovulation

Metformin

Carbegolline

Oocyte donation

Weight reduction

Weight gain

Measure serum androgen concentrations

Instrunctions:For each of the case histories described below, choose the single most appropriate
initial management from the above list. Each option may be used once, more than once, or not at
all.
Explanation

Question 6

A 24 year old woman with her 35 year old partner has been referred to
the infertility clinic because of 2 years of primary infertility. The
woman has an irregular menstrual cycle every 2-4 months and her
partner's semen analysis shows a volume of 2.5ml, concentration of
J
30,million/ml and motility of 65%. The woman?s BMI is 34 and there
is no significant past medical history. Investigations have confirmed a
diagnosis of polycystic ovary syndrome.

Options for Questions 7-7


A

Intravenous labetalol

Immediate delivery by caesarean section

Intravenous magnesium sulphate

Measure serum aspartate transaminase


immediately

Measure serum magnesium

Blood transfusion

Immediate induction of labour

Provide a fluid challenge with colloids

Antihypertensive treatment

Administer iv phenytoin

Measure 24h urine protein excretion

Place in left lateral position

Instrunctions:For each patient described below choose the single most appropriate management
option from the list. Each option may be used once, more than once, or not at all.
Explanation

Question 7

A 20-year-old primigravida has an emergency caesarean section at 30


weeks gestation because of severe gestational proteinuric hypertension
and IUGR. Her FBC, LFTs and U&E pre-op were within normal
limits. 12 hours after delivery, investigations show that her serum
C
lactate dehydrogenase concentration is markedly elevated, serum
aspartate transaminase concentration is 224 iu/l, platelet count is 80 x
10E9 /l and her renal function is normal. Her BP is 140/90 on oral
anti-hypertensive therapy and her urine out-put is 80ml/h.

Infertility / andrology / endocrinology EMQ-9

Options for Questions 8-8


A

Intravenous labetalol

Immediate delivery by caesarean section

Intravenous magnesium sulphate

Measure serum aspartate transaminase


immediately

Measure FBC and clotting profile

Blood transfusion

Immediate induction of labour

Provide a fluid challenge with colloids

Antihypertensive treatment

Administer iv phenytoin

Measure 24h urine protein excretion

Arrange in-utero transfer to tertiary


centre

Instrunctions:For each patient described below choose the single most appropriate management
option from the list. Each option may be used once, more than once, or not at all.
Explanation

Question 8

A 30 year old primigravida attends as an emergency at 32 weeks


gestation with a twin pregnancy and complains of 12h of severe
vomiting and upper abdominal pain. Her BP is 130/80mmHg with a
trace of proteinuria. A growth scan one week earlier had shown
normal fetal growth. Investigations show a serum aspartate
transaminase concentration of 600iu/l, alkaline phosphatase =
1550iu/l, serum uric acid = 0.57mmol/l and serum creatinine =
130micromol/l. FBC and coagulation profile are normal.

Options for Questions 9-9


A

Induction of labour

Discharge home

Community midwife follow-up

Anti-hypertensive therapy

Caesarean section at 39 weeks

Manage as out-patient with day


assessment unit

External cephalic version

Induction of labour at 40 weeks

Induction of labour at 42 weeks

Measure 24h urine protein excretion

Instrunctions:For each patient described below choose the single most appropriate management
option from the list. Each option may be used once, more than once, or not at all.
Explanation

Question 9

A 35 year old primigravida is an in-patient because of hypertension


and 1+ proteinuria on stix testing at 37 weeks gestation. Her BP is
130/80mmHg on oral methyldopa and all her blood tests are within
normal limits. 24h urine protein excretion is 200mg/24h.

Infertility / andrology / endocrinology EMQ-10

Options for Questions 10-10


A

Stage I cervical cancer

Stage Ia cervical cancer

Stage I endometrial cancer

Stage Ib endometrial cancer

Stage II cervical cancer

Stage IIb cervical cancer

Stage IIa cervical cancer

Stage IV endometrial cancer

Stage IV cervical cancer

Stage Ib cervical cancer

Stage IVa cervical cancer

Stage IIIb cervical cancer

Instrunctions:For each scenario described below, choose the single most appropriate tumour
stage from the above list of options. Each option may be used once, more than once, or not at all.
Explanation
An 87 year old woman has been referred to the gynaecology clinic
because of a 7 day history of frank haematuria. A fungating lesion is
Question 10
identified on her cervix and histology confirms a squamous cell
carcinoma. Cystoscopy shows invasion of the bladder mucosa

Options for Questions 11-11


A

Counsel and offer termination of


pregnancy

Counsel and offer rubella immune


globulin

Treat with intravenous zidovudine

Counsel and offer intra-uterine therapy

Offer amniocentesis for karyotype

Reassurance

Immunise neonate against rubella

Immunise mother against rubella

Treat with intravenous acyclovir

Amniocentesis and viral culture

Amniocentesis and PCR for fetal


viraemia

Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
A 20 year old student has been immunised against Rubella 2 weeks
before travelling to the UK. She attends as an emergency because she
Question 11 has missed a period and is found to be 10 weeks pregnant on
ultrasound scan. She is concerned about the effect of the vaccine on
her fetus

Options for Questions 12-12


A

Avoid breast-feeding

Administer VZIG to neonate and avoid


breast-feeding

Infertility / andrology / endocrinology EMQ-11

Administer VZIG to neonate but breastD


feeding encouraged

Immediate induction of labour

Delay delivery with tocolytics

Offer termination of pregnancy

Treat neonate with oral acyclovir

Treat neonate with intravenous


acyclovir

Examine neonate for evidence of


congenital anomalies

Reassurance

Delay delivery for 5-7 days if possible

Delay discharge for at least 7 days

Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
A 30 year old woman has delivered her second child by caesarean
section for breech presentation. While she is in hospital, she is
Question 12
informed that her 5 year old daughter has chickenpox. She has had
chicken pox in the past but is concerned about taking her baby home

Options for Questions 13-13


A

Stage I cervical cancer

Stage Ia cervical cancer

Stage I endometrial cancer

Stage Ib endometrial cancer

Stage II cervical cancer

Stage IIb cervical cancer

Stage IIa cervical cancer

Stage IV endometrial cancer

Stage IV cervical cancer

Stage Ib cervical cancer

Stage IVa cervical cancer

Stage IIIb cervical cancer

Instrunctions:For each scenario described below, choose the single most appropriate tumour
stage from the above list of options. Each option may be used once, more than once, or not at all.
Explanation
A 67 year old woman is referred to the gynaecology clinic with a 6
weeks history of post-menopausal bleeding. Clinical examination
Question 13 shows a fungating lesion on the cervix extending into the lower third
of the vagina. On rectal examination, the tumour extends to the pelvic
side-wall.

Options for Questions 14-14


A

Amniotic fluid embolism

Placental abruption

Cardiomyopathy

Placenta praevia

Infertility / andrology / endocrinology EMQ-12

Chest infection

Pulmonary embolism

CVA

Pulmonary hypertension

Endocarditis

Sepsis

Haemorrhage

Substance misuse

M HELLP syndrome

Thromboembolism

Myocardial infarcation

Instrunctions:For each case described below, choose the single most likely cause of maternal
death from the above list of options. Each option may be used once, more than once, or not at all.
Explanation
A 30 year old woman is re-admitted 3 days after spontaneous vaginal
delivery complaining of feeling generally unwell and having rigors.
She has a history of rheumatic fever and intravenous drug abuse.
Question 14
Clinical examination showed a temperature of 39C, bulky uterus with
offensive vaginal discharge and a new ejection systolic murmur. She
suffered a stroke 24h later and died.

Options for Questions 15-15


A

Administer H1N1 vaccine

Transfer to the intensive care unit

Deliver by caesarean section

Induce labour

Administer oseltamivir

Administer zanamivir

Avoid contact with partner

Transfer neonate to the neonatal


intensive care unit

Administer HINI vaccine to the neonate J

Take swabs for H1N1

Sputum for culture and sensitivity

Administer oseltamivir within 48 hours

M Administer zanamivir within 48 hours

Administer zanamivir within 36 hours

Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
An H1N1 influenza pandemic has been declared and a 35 year old
woman presents with a 24 hour history of flu-like illness with
Question 15 diarrhoea and vomiting. Her temperature is 38.5C, pulse 90 / min and
respiratory rate is 20 / min. SO2 is 96% on air. She had a vaginal
delivery 3 days earlier and is breastfeeding.

Options for Questions 16-16

Infertility / andrology / endocrinology EMQ-13

Congenital syphilis

Congenital varicella syndrome

Parvovirus B19 infection

Turner?s syndrome

Parder-Willy syndrome

Fetal hydantoin syndrome

Group B streptococcal infection

Congenital rubella syndrome

Cri-du-chat syndrome

Edward?s syndrome

Patau?s syndrome

Down?s syndrome

Instrunctions:For each of the case histories described below, choose the single most likely
cause of fetal abnormality from the above list of options. Each option may be used once, more
than once, or not at all.
Explanation
A 42 year old epileptic on phenytoin is late booking for antenatal care.
The estimated gestation age by ultrasound scan is 22 weeks and the
Question 16
L
fetus is found to have an atrio-ventricular septal defect and a double
bubble sign in the upper abdomen

Options for Questions 17-17


A

Quadruple test

Integrated test

Nuchal transluscency

Serum integrated test

Triple test

Anomaly scan

Fluorescent in-situ hybridisation

Amniocentesis

Chorionic villus sampling

PCR

No investigation

Fetal blood sampling

Instrunctions:For each of the case histories described below, choose the single most important
investigation from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
Question 17

A 30 year old woman is found to have a fetus with duodenal atresia on


H
anomaly scan at 20 weeks gestation

Options for Questions 18-18


A

Amniocentesis

Chorionic villus sampling

Fetal blood sampling

Triple test

Quadruple test

Integrated test

Serum integrated test

Nuchal transluscency

Infertility / andrology / endocrinology EMQ-14

Anomaly scan

Fluorescent in-situ hybridisation

PCR

Restriction fragment length


polymorphisms

Instrunctions:For each of the case histories described below, choose the single most appropriate
investigation from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
A 30 year old woman is known to be a carrier of Haemophilia A.
Question 18 Amniocentesis at 16 weeks gestation shows that she is carrying an
unaffected male fetus. She is now 20 weeks pregnant.

Options for Questions 19-19


A

Fetal blood sampling

Triple test

Quadruple test

Integrated test

Chorionic villus sampling

Serum integrated test

Amniocentesis

Nuchal transluscency

Anomaly scan

Fluorescent in-situ hybridisation

PCR

Restriction fragment length


polymorphisms

M Karyotype
Instrunctions:For each of the conditions described below, choose the single most appropriate
diagnostic tests from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
Question 19 Down?s syndrome

Options for Questions 20-20


A

Cystoscopy and cystodistension

Bladder re-training

Tension-free vaginal tape

Anterior repair + TVT

Posterior repair

Paravaginal repair

Para-urethral collagen injection

Tolterodine + bladder re-training

Pelvic floor physiotherapy

Duloxetine

Amitriptyline

Oestrogen replacement therapy

Infertility / andrology / endocrinology EMQ-15

Instrunctions:For each of the case histories described below, choose the single most appropriate
treatment option from the above list of options. Each option may be used once, more than once,
or not at all.
Explanation
A 30 year old woman presents 6 months after spontaneous vaginal
delivery with urinary leakage on coughing and straining. Clinical
Question 20
examination was normal and urinary leakage was not demonstrated
with coughing.

Options for Questions 21-21


A

Cystoscopy & cystodistension

Cystoscopy

Urine microscopy, culture and


sensitivity

Cystometry

Pelvic ultrasound scan

Colposuspension

Bladder retraining

Three swab test

Intra-venous urogram

Return to theatre

Catheterise

Pelvic floor exercises

Instrunctions:For each of the case histories described below, choose the single most appropriate
initial management from the above list of options. Each option may be used once, more than
once, or not at all.
Explanation
A 45 year old woman complains of feeling wet all the time 10 days
after a radical hysterectomy for cervical cancer. Clinical examination
Question 21 showed a small amount of clear fluid in the vagina but no other
abnormalities. A three swab test showed a wet swab which was not
stained with dye.

Options for Questions 22-22


A

Cystoscopy

MRI scan

Urodynamic studies

Bladder re-training

Urine for cytology

Cystoscopy and biopsy

Examination under anaesthesia

MSU for culture and sensitivity

Urine electrolytes

Renal function tests

Instrunctions:For each of the case histories described below, choose the single most important
investigation from the above list of options. Each option may be used once, more than once, or
not at all.

Infertility / andrology / endocrinology EMQ-16

Explanation
A 45 year old woman complained initially of urinary frequency
urgency and urge incontinence and also leaked urine on coughing or
straining. She was treated medically initially and her symptoms of
Question 22
urinary frequency and urgency have largely resolved. Over the last 6
months, she is finding that urinary leakage on coughing and straining
is increasingly affecting her social life.

Options for Questions 23-23


A

Rhesus disease

Parvovirus infection

Beta thalassaemia

Sickle cell disease

Syphilis infection

Congenital heart disease

Idiopathic

Congenital diaphragmatic hernia

Twin-to-twin transfusion syndrome

Congenital toxoplasmosis

Alpha thalassaemia

Chronic feto-maternal haemorrhage

Instrunctions:For each of the case histories described below, choose the single most likely
cause of fetal hydrops from the above list of options. Each option may be used once, more than
once, or not at all.
Explanation
A 24 year old woman with beta thalassaemia trait is referred for
growth scan at 30 weeks gestation in her first pregnancy and is found
Question 23 to have a hydropic fetus. She is Rhesus negative with no red cell
antibodies. Her partner has beta thalassaemia trait and all other
investigations are normal

Options for Questions 24-24


A

Deliver by caesarean section

Induction of labour

Termination of pregnancy

Selective fetocide by intra-cardiac KCl


injection

Selective fetocide by cord occlusion

Laser ablation of placental anastomoses

Septostomy

Amnioreduction

Serial ultrasound scans

Detailed fetal cardiac scan

No treatment recommended

Corticosteroids for fetal lung maturity

Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all.

Infertility / andrology / endocrinology EMQ-17

Explanation
A 35 year old woman with twin-to-twin transfusion syndrome has
been treated at the fetal medicine unit and both pregnancies are
Question 24
progressing well. Corticosteroids had been administered at 30 weeks
gestation and she has attended for ultrasound scan at 32 weeks.

Options for Questions 25-25


A

No additional intervention at this stage

Deliver by caesarean section

Increase dose of oxytocin

Lovset?s manoeuvre

Decrease dose of oxytocin

Fetal blood sampling

Forceps delivery

Delivery of the posterior arm

Episiotomy

Inhaled salbutamol

McRobert?s manoeuvre

Administer maternal facial oxygen

Instrunctions:For each of the case histories described below, choose the single most appropriate
management from the above list. Each option may be used once, more than once, or not at all.
Explanation
A 34 year old woman with 3 previous vaginal deliveries presents in
spontaneous labour at 39 weeks gestation. The cervix is fully dilated
with thick meconium stained liquor. The CTG shows a base-line fetal
Question 25 heart rate of 135bpm with variability of 3-4bpm with variable
G
decelerations. There are 3-4 uterine contractions every 10 minutes.
The fetus is in a direct occipito-anterior position 1cm below the ischial
spines.

Options for Questions 26-26


Add COCP containing second
generation progestogen for up to 3
months

Add COCP containing third generation


progestogen for up to 3 months

Add progesterone-only pill for 3 months D

Give next dose of depomedroxyprogesterone acetate 4 weeks


earlier

Tranexamic acid during bleeding

Use progestogen-only implant

Add 30mcg ethinyloestradiol daily for 3


H
months

Stop depo-medroxyprogesterone acetate

Administer another dose of depomedroxyprogesterone acetate

Add desogestrel-only pill

Add COCP for 1 week

Mefenamic acid 500mg 2-3 times / day


for 3 months

Infertility / andrology / endocrinology EMQ-18

Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all
Explanation
A healthy 28 year old woman complains of irregular vaginal bleeding
Question 26 3 weeks after her first dose of depo-medroxyprogesterone acetate.
History and clinical examination are normal

Options for Questions 27-27


A

Congenital adrenal hyperplasia

Maternal androgen therapy

Down?s syndrome

Turner?s syndrome

Maternal diabetes mellitus

Maternal lithium therapy

Maternal warfarin therapy

Maternal heparin therapy

Group B streptococcus infection

Maternal anti-epileptic drug therapy

Maternal smoking

Maternal cocaine abuse

Instrunctions:For each of the case histories described below, choose the single most likely
cause of neonatal collapse from the above list of options. Each option may be used once, more
than once, or not at all.
Explanation
Question 27 A 3 hour old neonate weighing 4900g at birth

Options for Questions 28-28


A

Congenital adrenal hyperplasia

Maternal androgen therapy

Down?s syndrome

Turner?s syndrome

Maternal diabetes mellitus

Maternal lithium therapy

Maternal warfarin therapy

Maternal heparin therapy

Group B streptococcus infection

Maternal anti-epileptic drug therapy

Maternal smoking

Maternal cocaine abuse

Instrunctions:For each of the case histories described below, choose the single most likely
cause of neonatal collapse from the above list of options. Each option may be used once, more
than once, or not at all.
Explanation
Question 28 A 6 hour old neonate with ambiguous genitalia

Infertility / andrology / endocrinology EMQ-19

Options for Questions 29-29


A

Congenital adrenal hyperplasia

Maternal androgen therapy

Down?s syndrome

Turner?s syndrome

Maternal diabetes mellitus

Maternal lithium therapy

Maternal warfarin therapy

Maternal heparin therapy

Group B streptococcus infection

Maternal anti-epileptic drug therapy

Maternal smoking

Maternal cocaine abuse

Instrunctions:For each of the case histories described below, choose the single most likely
cause of neonatal collapse from the above list of options. Each option may be used once, more
than once, or not at all.
Explanation
A 6 hour old neonate delivered by rotational forceps delivery for
prolonged second stage of labour. Initial examination showed
Question 29
C
epicanthic folds with up-slanting palpebral fissures and a loud systolic
murmur

Options for Questions 30-30


A

Can be delivered in a midwifery-led unit B

Can have a home birth

Should deliver in a consultant-led unit

Should have venous access in the


second stage of labour

Should have an anaesthetist at ST3 level


F
or above available

Should have an obstetrician at ST3 level


or above available

Consultant obstetrician should be


immediately available

Consultant anaesthetist should be


immediately available

Should have an anaesthetist at ST6 level


J
or above available

Should be delivered in a tertiary centre

Should have venous access in the third


stage of labour

Should have blood cross-matched


during labour

Instrunctions:For each scenario described below, choose the single most appropriate plan for
labour from the above list of options. Each option may be used once, more than once, or not at
all.
Explanation
A 35 year old woman has attended the consultant antenatal clinic at 36
Question 30 weeks gestation to discuss her birth plan. Her BMI was 42 at booking I
and 45 at 36 weeks. Her pregnancy is otherwise uncomplicated

Infertility / andrology / endocrinology EMQ-20

Options for Questions 31-31


A

Produces visible light

Produces light which can be transmitted


through fibre optic systems

Is not absorbed by pigmented tissue

Produces tissue damage to a depth of 0.2


mm

Produces tissue damage to a depth of


0.02 mm

Cannot be transmitted through clear


fluids

Requires a series of articulated mirrors


for transmission

Is not suitable for tissue coagulation

Produces ultra violet light

Is no longer recommended for use in


surgical procedures

Instrunctions:For the statement below, select the single most appropriate option from the above
list of options. Each option may be used once, more than once, or not at all.
Explanation
Question 31 The Nd:YAG laser

Options for Questions 32-32


A

No further treatment

Adjuvant chemotherapy

External beam radiotherapy

Intracavitary radiotherapy

Intra-peritomeal chemotherapy

TAH + unilateral salpingo-oophrectomy

Unilateral salpingo-oophrectomy

Monthly pelvic ultrasound scans

Monthly pelvic ultrasound scans +


tumour markers

Ovarian stimulation + IVF

TAH

Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
A 37 year old woman with a complex ovarian mass had a staging
laparotomy with unilateral salpingo-oophrectomy to conserver
fertility. Peritoneal washings, the omentum and peritoneal biopsies are
Question 32 negative. There is a poorly differentiated clear cell adenocarcinoma
B
confined to the ovary and the ovarian capsule is not invaded. There is
invasion of lymphovascular space. Biopsies from the conserved ovary
and lymph nodes are normal.

Infertility / andrology / endocrinology EMQ-21

Options for Questions 33-33


A

Total abdominal hysterectomy

Repeat colposcopy in 6 weeks

Repeat colposcopy in 6 months

Laser ablation

Cryotherapy

Laser cone biopsy

Radical abdominal hysterectomy

Radical abdominal hysterectomy +


pelvic lymphadenectomy

Intracavitary radiotherapy

External beam radiotherapy

Radical abdominal hysterectomy +


external beam radiotherapy

Radical abdominal hysterectomy +


pelvic lymphadenectomy + external
beam radiotherapy

Total abdominal hysterectomy +


bilateral salpingo-oophrectomy

Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
A 42 year old mother of 5 children is found to have severe dyskaryosis
Question 33 on routine cervical smear. Colposcopy and biopsy confirms carcinoma A
in-situ.

Options for Questions 34-34


A

Repeat colposcopy in 6 weeks

Total abdominal hysterectomy

LLETZ

Cold knife cone biopsy

Radical hysterectomy + pelvic


lymphadenectomy

External beam radiotherapy

Intracavitary radiotherapy

Intracavitary + external beam


radiotherapy

Combined chemo-radiotherapy

Total abdominal hysterectomy + BSO

Cryotherapy

Cold knife cone biopsy + laparoscopic


pelvic lymphadenectomy

Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
A 32 year old mother of 4 children has a cervical smear showing
Question 34 severe dyskaryosis. Colposcopy identifies a 3 x 4 mm lesion on the
ectocervix. Punch biopsy confirms a squamous cell carcinoma with

Infertility / andrology / endocrinology EMQ-22

depth of invasion of 1.5mm. There is no invasion of the lymphovascular space. The woman has completed her family.

Options for Questions 35-35


A

Total abdominal hysterectomy

Total abdominal hysterectomy + BSO

Radical hysterectomy + pelvic


lymphadenectomy + chemotherapy

Radical hysterectomy + pelvic


lymphadenectomy + radiotherapy

External beam radiotherapy

Intracavitary radiotherapy

Chemotherapy + intracavitary and


external beam radiotherapy

Chemotherapy

Radical hysterectomy + para-aortic


lymphadenectomy

Palliative care

Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
A healthy 60 year old woman presents with a 6 months history of postcoital bleeding. Clinical examination identifies a 3cm ulcerated lesion
on the cervix extending into the upper third of the vagina. Biopsy
Question 35
G
confirms squamous cell carcinoma. MRI scan confirms that the
tumour is limited to the upper third of the vagina and there is
parametrial invasion. The pelvic side-wall is not involved.

Options for Questions 36-37


A

Cerazette (desogestrel) progestogenonly pill

Noriday (norethisterone) progestogenonly pill

Norgeston (Levonorgestrel)
Progestogen-only pill

Combined oral contraceptive pill

Depo-medroxyprogesterone acetate

Depo- Norethisterone oenanthate

Copper IUCD

Levonorgestrel IUS

Etonorgestrel implant

Male condom

Levonorgestrel post-coital contraception L

All options may be used

Instrunctions:For each scenario described below, choose the contraceptive option that should
not be used (UKMEC category 3 or 4) from the above list of options. Each option may be used
once, more than once, or not at all.
Explanation

Infertility / andrology / endocrinology EMQ-23

A 23 year old woman has undergone termination of an unwanted


Question 36 pregnancy at 12 weeks gestation. She gives a history of migraine
without aura. Her BMI is 25 kg/m2 and she is a non-smoker.

A 33 year old woman has undergone termination of an unwanted


pregnancy at 18 weeks. She has a history of suicidal depressive illness
Question 37
L
that is currently well controlled with anti-depressants. Her BMI is 22
kg/m2 and she is a non-smoker.

Options for Questions 38-38


A

Total abdominal hysterectomy

Total abdominal hysterectomy + BSO +


D
pelvic lymphadenectomy

Total abdominal hysterectomy + BSO +


omentectomy

Total abdominal hysterectomy + BSO +


F
para-aortic lymphadenectomy

Total laparoscopic hysterectomy + BSO

Intracavitary radiotherapy

Intracavitary + external beam


radiotherapy

Total abdominal hysterectomy + BSO +


J
radiotherapy

Total abdominal hysterectomy + BSO +


chemotherapy

Total abdominal hysterectomy + BSO +


L
combined chemo-radiotherapy

Radical abdominal hysterectomy + BSO

Radical abdominal hysterectomy + BSO


+ pelvic lymphadenectomy

Total abdominal hysterectomy + BSO

Instrunctions:For each scenario described below, choose the appropriate treatment option that is
associated with the lowest risk of morbidity from the above list of options. Each option may be
used once, more than once, or not at all.
Explanation
A healthy 67 year old woman has been referred to the gynaecology
oncology clinic with a 3 months history of post-menopausal bleeding.
Endometrial biopsy shows a well differentiated endometrial
Question 38
carcinoma. MRI scanning shows that the tumour is confined to the
inner 50% of the myometrium but extends to the endocervical glands.
There is no invasion of the cervical stroma

Options for Questions 39-40


A

Perform amniotomy

Deliver by caesarean section

Reassess in 2 hours

Reassess in 3 hours

Reassess in 4 hours

Commence CTG and reassess in 2 hours

Commence CTG and reassess in 3 hours H

Commence CTG and reassess in 4 hours

Perform amniotomy and commence

Commence oxytocin infusion

Infertility / andrology / endocrinology EMQ-24

CTG
K

Commence oxytocin infusion and CTG

Administer vaginal prostaglandin tablets


3mg

M No additional intervention
Instrunctions:For each scenario described below, choose the single most appropriate
management from the above list of options. Each option may be used once, more than once, or
not at all.
Explanation
A 34 year old woman with a dichorionic-diamniotic twin pregnancy
presents in spontaneous labour at 37 weeks gestation. At 08:00, the
Question 39
cervix is 4cm dilated with intact membranes. At 12:00, the cervix is
5cm dilated with intact membranes. She is contracting 3-4 in 10.

A healthy 39 year old woman presents with pre-labour rupture of the


membranes at 39 weeks gestation. Re re-attends 8 hours later in
Question 40 spontaneous labour and the cervix is 6cm dilated with a direct
occipito-posterior position. Four hour later, the cervix is 7cm dilated
with a left occipito-transverse position.

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