8/25/2016 ChemIDplus - 7487-88-9 - CSNNHWWHGAXBCP-UHFFFAOYSA-L - Magnesium sulfate anhydrous - Similar structures search, synonyms, formulas, resour

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Na +

3D

Substance Name: Magnesium sulfate anhydrous

RN: 7487-88-9
UNII: ML30MJ2U7I
InChIKey: CSNNHWWHGAXBCP-UHFFFAOYSA-L
Note
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and
eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which
decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)

Molecular Formulas
H2-O4-S.Mg
O4-S.Mg

Molecular Weight
120.367
All

Classifications

Links to Resources

Names & Synonyms

Registry Numbers

Formulas

Structure Descriptors

Toxicity

Classification Codes
Analgesics
Anesthetics
Anti-Arrhythmia Agents
Anticonvulsants
Calcium Channel Blockers
Cardiovascular Agents
Central Nervous System Agents
Central Nervous System Depressants
Drug / Therapeutic Agent
Human Data
Membrane Transport Modulators
Mutation Data
Peripheral Nervous System Agents
Reproductive Control Agents
Reproductive Effect
Sensory System Agents
Tocolytic Agents

* denotes mobile formatted website

Links to Resources
https://chem.sis.nlm.nih.gov/chemidplus/rn/7487-88-9

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Search for this InChIKey on the Web

Names and Synonyms
Name of Substance
Magnesium sulfate
Magnesium sulfate anhydrous
Sulfuric acid, magnesium salt (1:1)
MeSH Heading
Magnesium sulfate
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Synonyms
Arrosalt 2327
Caswell No. 534
CCRIS 8411
EC 231-298-2
EINECS 231-298-2
EPA Pesticide Chemical Code 050503
Epsom salt
Epsom salts
HSDB 664
Magnesii sulfas
Magnesium sulfate
Magnesium sulfate (1:1)
Magnesium sulfate in dextrose 5% in plastic container
Magnesium sulfate in plastic container
Magnesium sulphate
NSC 146179
OT-S
OT-S (drying agent)
Sal Angalis
Sal De sedlitz
SN 00
Sulfato de magnesio
Sulfuric acid magnesium salt
Sulfuric acid magnesium salt (1:1)
Sulfuric acid magnesium salt (VAN)
Tomix OT
UNII-ML30MJ2U7I
Systematic Names
Magnesium sulfate (1:1)
Magnesium sulphate
Sulfuric acid magnesium salt (1:1)
Superlist Name
Magnesium sulfate

Registry Numbers
CAS Registry Number
7487-88-9
FDA UNII
ML30MJ2U7I
Other Registry Numbers
139939-75-6
849607-35-8
Related Registry Number
10034-99-8 (heptahydrate)
System Generated Number
0007487889

Molecular Formulas
Molecular Formulas
H2-O4-S.Mg
O4-S.Mg
Molecular Formula Fragments
COMPONENT
H2-O4-S
Mg
O4-S
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O4-S

Structure Descriptors
InChI

1S/Mg.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2
Download

InChIKey

CSNNHWWHGAXBCP-UHFFFAOYSA-L
Search the web for this InChIKey

Smiles

S(=O)(=O)([O-])[O-].[Mg+2]
Download

Toxicity
Organism Test Route
Type
cat

Reported
Effect
Dose
(Normalized
Dose)
LDLo subcutaneous 1gm/kg
BEHAVIORAL: GENERAL
(1000mg/kg) ANESTHETIC
LDLo intraperitoneal 1200mg/kg
(1200mg/kg)

Source

American Journal of Physiology. Vol. 14,

Pg. 366, 1905.
dog
"Abdernalden's Handbuch der
Biologischen Arbeitsmethoden." Vol. 4,
Pg. 1364, 1935.
dog
LDLo subcutaneous 1500mg/kg
"Abdernalden's Handbuch der
(1500mg/kg)
Biologischen Arbeitsmethoden." Vol. 4,
Pg. 1364, 1935.
guinea pig LDLo subcutaneous 1800mg/kg BEHAVIORAL: SOMNOLENCE
American Journal of Physiology. Vol. 14,
(1800mg/kg) (GENERAL DEPRESSED ACTIVITY) Pg. 366, 1905.

man

TDLo oral

428mg/kg
(428mg/kg)

BEHAVIORAL: GENERAL
ANESTHETIC
BEHAVIORAL: MUSCLE
WEAKNESS

Japanese Journal of Toxicology. Vol. 2,

Pg. 285, 1989.

LUNGS, THORAX, OR
RESPIRATION: OTHER CHANGES
mouse
mouse

LD50 intraperitoneal 1029mg/kg

(1029mg/kg)
LD50 subcutaneous 645mg/kg
(645mg/kg)

mouse

LDLo intravenous

48mg/kg
(48mg/kg)
5gm/kg
(5000mg/kg)

mouse

LDLo oral

rabbit

LDLo oral

rabbit

LDLo subcutaneous 1750mg/kg LUNGS, THORAX, OR

(1750mg/kg) RESPIRATION: OTHER CHANGES

3gm/kg
(3000mg/kg)

Farmakologiya i Toksikologiya Vol. 10,

Pg. 107, 1975.
Zhongguo Yaoli Xuebao. Acta
Pharmacologica Sinica. Chinese Journal
of Pharmacology. Vol. 7, Pg. 178, 1986.
Toxicology and Applied Pharmacology.
Vol. 4, Pg. 492, 1962.
"Abdernalden's Handbuch der
Biologischen Arbeitsmethoden." Vol. 4,
Pg. 1364, 1935.
"Abdernalden's Handbuch der
Biologischen Arbeitsmethoden." Vol. 4,
Pg. 1364, 1935.
American Journal of Physiology. Vol. 14,
Pg. 366, 1905.

BEHAVIORAL: CONVULSIONS OR
EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: SOMNOLENCE
(GENERAL DEPRESSED ACTIVITY)
rat

LD50 subcutaneous 1200mg/kg

(1200mg/kg)
women
LDLo intravenous 80mg/kg/2M- CARDIAC: OTHER CHANGES
I (80mg/kg)
LUNGS, THORAX, OR
RESPIRATION: CYANOSIS
women
TDLo intraspinal
20mg/kg
PERIPHERAL NERVE AND
(20mg/kg)
SENSATION: FLACCID PARALYSIS
WITH APPROPRIATE ANESTHESIA
women
TDLo oral
351mg/kg
BLOOD: "CHANGES IN SERUM
(351mg/kg) COMPOSITION (E.G., TP,
BILIRUBIN, CHOLESTEROL)"
https://chem.sis.nlm.nih.gov/chemidplus/rn/7487-88-9

Neuroscience Letters. Vol. 117, Pg. 207,

1990.
South African Medical Journal. Vol. 67,
Pg. 145, 1985.
South African Medical Journal. Vol. 68,
Pg. 367, 1985.
Journal of Toxicology, Clinical Toxicology.
Vol. 34, Pg. 735, 1996.
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BILIRUBIN, CHOLESTEROL)"
BEHAVIORAL: MUSCLE
WEAKNESS
CARDIAC: ARRHYTHMIAS
(INCLUDING CHANGES IN
CONDUCTION)

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