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Skills Lab #4

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1.

Absorption

Refers to the movement of the drug from the


site of administration into the blood stream.

2.

Acute pain

A short duration of pain and is generally rapid


onset may last up to six months

3.

Adverse
reaction

Are harmful, unintended, usually unpredicted


reactions to a drug administered at the normal
dosage, they are more severe than side
effects.

4.

5.

6.

antagonistic

Brand/trade
name

Chemical
name

One drug interferes with the actions of another


and decreases the resultant drug effect, that is
the combined effect is less than the that of
one drug given alone.
When drug is marketed manufacturer sells
under brand name this is easily recognized
because it begins with a capital letter and
sometimes registration mark at the upper right
of the name. 496
The exact description of the drugs chemical
composition and molecular structure. eg- 2-(pisobutylphenyl) propionic acid is chemical name
for ibuprofen.

7.

Chronic Pain

Pain that has lasted six months or longer and


often interferes with daily activities.

8.

Distribution

Is the transportation of a drug in body fluids


(usually the blood stream) to the various
tissues and organs of the body.

9.

Duration of
action

That period of time in which the medication has


a pharmacological effect.

10.

Excretion

For this to occur the drug molecules must be


removed from their sites of action and
eliminated from the body.

11.

Generic
name

Usually similar to chemical name but simpler.


Also this is the official name that is listed in
publications. eg-ibuprofen

12.

Half life

The amount of time it takes for half of the drug


to be eliminated.

13.

Idiosyncratic

Is an unexpected, abnormal, or peculiar


response to a medication.

14.

Inhalation

Breathing into the lungs; a medication delivery


route.

15.

Intractable
Pain

Pain that is both chronic and highly resistant to


relief.

16.

Metabolism

Or biotransformation is the chemical


inactivation of a drug through its conversion
into a more water soluble compound or into
metabolites that can be excreted from the
body. Once a drug reaches its site of action it
is metabolized in preparation for excretion.

17.

Metered
dose inhaler
(MDI)

A pressurized container prefilled with several


doses of a drug and an ecofriendly substance
called hydrofluoroalkane (HFA) for propelling
the medication forward. (pg 527)

18.

Modulation

A process that changes the perception of pain


by either facilitating or inhibiting pain signals. (
the endogenous analgesia system and the
gate- control mechanism)

19.

Nebulizer

The production of a fine spray fog, powder, or


mist from a liquid drug

20.

Neuropathic
Pain

A complex and often chronic pain that arises


when injury to one or more nerves results in
repeated transmission of pain signals even in
the absences of painful stimulation

21.

Onset of
action

The time needed for drug concentrations to


reach a high enough blood level for its effects
to appear.

22.

Pain
perception

Involves the recognition and definition of pain


in the frontal cortex.

23.

Palliative
effects

Relieve the signs and symptoms of a disease


but have no effect on the disease itself. egmorphine sulfate to manage pain of cancer but
will not destroy cancer cells.

24.

Peak Action

When the concentration of the medication is


highest in the blood.

25.

Side effects

Are unintended, often predictable,


physiological effects that are usually well
tolerated by patients.

26.

Small
volume
nebulizer

SVN a pneumatically powered device used to


aerosolize medications for delivery to patients.

27.

Sublingual

Medication placed under the tongue

28.

Suppository

Drugs mixed with a glycerin-gelatin or cocoa


butter base and shaped for insertion into the
body. They dissolve gradually at body
temperature. (table 23-1 pg503)

29.

Synergistic

There Is an additive effect, that is the effect


of both drugs together is greater than the
individual effects.

30.

Toxic
reaction

Are dangerous, damaging effects to an organ


or tissue they are more serious than adverse
reactions can cause death or permanent
damage.

31.

Transdermal

A patch that releases constant, controlled


amounts of medication for systemic
effect.(table 23-1 pg503)

32.

Transduction

A process where nociceptors become


activated by the perception of potentially
damaging mechanical, thermal, and chemical
stimuli.

33.

Transmission

Peripheral nerves carry the pain message to


the dorsal horn of the spinal cord in this
process.

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