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Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Adenovirus

Febrile Pharyngitis;
Acute Hemorrhagic
Cystitis; Pneumonia;
Conjunctivitis

Sore throat; cough +


mucus/phlegm,
wheezing, shortness
of breath, fever, and
chest discomfort;
chills, tachycardia;
diarrhea; eye
redness/itchiness;
gritty feeling,
discharge that forms
a crust during the
night that may
prevent your eye or
eyes from opening
in the morning,
tearing; lower
abdominal
discomfort, dysuria,
hematuria

Person to person
close contact,
coughing,
sneezing, touching
an object or
surface with
adenoviruses on it,
then touching your
mouth, nose, or
eyes before
washing your
hands; infected
stool; swimming
pools (less
common)

dsDNA,
Linear

Icosahedral

Terrance Garnett

Virus Pathogens List

No Envelope; DNA Viruses

Summer 2016

Bunyavirus

California
Encephalitis;
Sandfly/Rift Valley
Fevers; CrimeanCongo Hemorrhagic
Fever; HantavirusHemorrhagic Fever;
Pneumonia

Ocular disease
Lesions on the eyes
+ blurred and
decreased vision;
Encephalitis
headaches, coma, or
seizures; (symptoms
of hemorrhaging)
jaundice + other
signs of liver
impairment,
followed by
vomiting blood,
bloody stool, or
bleeding from gums,
skin, nose, and
injection sites;
fatigue, fever and
muscle aches
(thighs, hips, back,
shoulders) +
headaches,
dizziness, chills, and
abdominal problems
(nausea, vomiting,
diarrhea, pain) et al.

Coronavirus

Common Cold;
SARS, MERS

Terrance Garnett

mild to moderate
upper-respiratory
tract illnesses
(URIs), symptoms
include: [short

Ixodid (hard) ticks


transmission
through contact
with infected ticks
or animal blood

ssRNA, (),
Circular, three
(3) Segments

Helical

Yes Envelope; RNA Virus;


Bunyaviridae Family of
Viruses: Five (5) Genera
bunyavirus, phlebovirus,
nairovirus, tospovirus, &
hantavirus

ssRNA, (+),
Linear

Helical

Yes Envelope

deer mice, cotton


rats, rice rats,
white-footed
mouse = reservoir
of the virus
rodents shed the
virus in their urine,
droppings, and
saliva
transmitted to
people when they
breathe in air
contaminated with
the virus fresh
rodent urine,
droppings, or
nesting materials
are stirred up, tiny
droplets containing
the virus get into
the air (airborne
transmission) et al.
Ways that
common human
coronaviruses
spread have not
been studied very

Virus Pathogens List

Summer 2016

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

duration] runny
nose, cough, sore
throat, fever

much likely
spread from
infected person
through air
(coughing &
sneezing) + close
personal contact
(touching or
shaking hands or
contaminated
objects)

lower-respiratory
tract illnesses
(LRIs): pneumonia
[common in Pts
w/cardiopulmonary
disease or
compromised
immune systems, or
the elderly]

Terrance Garnett

Virus Pathogens List

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Summer 2016

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Flaviviruses

HCV;

No illness or only
mild illness (i.e.
Yellow Fever, Zika)
fever, chills, severe
headache, back pain,
general body aches,
nausea/vomiting,
fatigue, weakness;

transmitted to
people primarily
through the bite of
infected Aedes or
Haemagogus
species
mosquitoes;

ssRNA, (+),
Linear

Icosahedral

Yellow Fever;
Dengue;
St. Louis
Encephalitis;
West Nile Virus;
Zika virus

Severe eye pain,


joint pain, muscle +
bone pain, rash, mild
bleeding
manifestation (nose
or gum bleed,
petechiae, or easy
bruising), low white
cell count;

Yes Envelope

transmitted
between people by
the mosquitoes
Aedes aegypti and
Aedes albopictus
found throughout
the world;

transmitted to
people primarily
through the bite of
Neurologic illness - an infected Aedes
neck stiffness,
species mosquito
disorientation, coma, (Ae. aegypti and
tremors, seizures, or Ae. albopictus)
paralysis; et al.
same mosquitoes
that spread dengue
& chikungunya
viruses; et al.

Terrance Garnett

Virus Pathogens List

Summer 2016

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Togaviruses

Eastern Equine
Encephalitis; Western
Equine Encephalitis;
Rubella

typical rash and


lymphadenopathy;

transmitted via
direct or droplet
contact with
respiratory
secretions;
(Rubella virus)
multiplies in cells
of the respiratory
system viremic
spread to target
organs; congenital
infection is
transmitted
transplacentally; et
al.

ssRNA, (+),
Linear

Icosahedral

Terrance Garnett

Signs and symptoms


in encephalitic
patients: fever,
headache,
irritability,
restlessness,
drowsiness,
anorexia, vomiting,
diarrhea, cyanosis,
convulsions, and
coma; et al.

Virus Pathogens List

Yes Envelope

Summer 2016

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Filoviruses

Ebola; Marburg
Hemorrhagic Fever
(often fatal)

Diarrhea/Vomiting,
Abdominal
(stomach) pain,
Unexplained
hemorrhage
(bleeding or
bruising);

Spread to others
through direct
contact broken
skin or mucous
membranes: eyes,
nose, or mouth;
blood or body
fluids - urine,
saliva, sweat,
feces, vomit,
breast milk, and
semen) of a person
who is sick with or
has died from
Ebola; infected
fruit bats or
primates (apes and
monkeys);

ssRNA, (),
Linear

Helical

fever, chills,
headache, myalgia;
maculopapular rash

Yes Envelope

Nosocomial
transmission

Terrance Garnett

Virus Pathogens List

Summer 2016

Enterovirus
(Picornaviruses)

Poliovirus PolioSalk/Sabin vaccines:


IPV/OPV; Echovirus
Aseptic Meningitis;
Rhinovirus
Common Cold;
Coxsackievirus
Aseptic Meningitis;
Herpangina (mouth
blisters, fever); Hand,
Foot, & Mouth
Disease; Myocarditis;
Pericarditis; HAV
Acute Viral Hepatitis

Terrance Garnett

Mild illness
includes: fever,
runny nose,
sneezing, cough,
skin rash, mouth
blisters, body and
muscle aches
infection NonPolio Enterovirus:
viral conjunctivitis;
viral meningitis
(infection of the
covering of the
spinal cord and/or
brain); viral
encephalitis
(infection of the
brain); myocarditis
(infection of the
heart); pericarditis
(infection of the sac
around the heart);
acute flaccid
paralysis (a sudden
onset of weakness in
one or more arms or
legs); inflammatory
muscle disease
(slow, progressive
muscle weakness)

Close contact
shaking hands,
touching objects,
or surfaces that
have the virus on
them; drinking
water that has the
virus in it;

ssRNA, (+),
Linear

Icosahedral

No Envelope

Pregnant women
who are infected
with a non-polio
enterovirus shortly
before delivery can
pass the virus to
their babies

Virus Pathogens List

Summer 2016

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Epstein-Barr Virus
(HHV-4)

Infectious
Mononucleosis
fever,
hepatosplenomegaly,
pharyngitis,
lymphadenopathy
(posterior cervical
nodes);

Fatigue, fever,
inflamed throat,
swollen lymph
nodes in the neck,
enlarged spleen,
swollen liver, rash

Respiratory
Secretions, Saliva,
kissing disease,
(common in teens,
young adults)

dsDNA,
Linear

Icosahedral

fever, runny nose,


headache rash on
your face and body
(slapped cheek)
develop pain and
swelling in their
joints
(polyarthropathy
syndrome)

spreads through
respiratory
secretions (saliva,
sputum, or nasal
mucus) when an
infected person
coughs or sneezes

ssDNA, Linear Icosahedral


(smallest DNA
virus)

Associated with
lymphomas (e.g.
Endemic Burkitt
Lymphoma),
nasopharyngeal
carcinoma
Parvovirus

Erythrovirus B19
aplastic crises in
sickle cell disease,
slapped cheeks,
rash in children
[Erythema
Infectiosum, or Fifth
(5th) Disease]
Feline Panleukopenia

Terrance Garnett

Virus Pathogens List

Avoid contact sports until


resolution due to risk of
splenic rupture; Infects B
cells through CD21; Yes
Enveloped; Atypical
Lymphocytes on blood
smear not infected B
cells, reactive cytotoxic T
cells; Monospot Test =
heterophile antibodies
detected by agglutination of
sheep/horse RBCs

No Envelope

Summer 2016

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Hantavirus (see
Bunyavirus)

Hantavirus
Pulmonary Syndrome
(HPS), Hemorrhagic
Fever with Renal
Syndrome (HFRS)

fatigue, fever +
muscle aches,
headaches,
dizziness, chills,
nausea, vomiting,
diarrhea, &
abdominal pain

(United States)
ssRNA, (),
deer mice, cotton
Circular, three
rats, rice rats,
(3) Segments
white-footed
mouse = are the
reservoir of the
virus; rodents shed
virus in their urine,
droppings, +
saliva; transmitted
to people when
they breathe in air
contaminated with
the virus
airborne
transmission

Helical

Hantaviruses replicate
exclusively in the host cell
cytoplasm; HPS can be fatal,
mortality rate of 38%

Hepatitis A Virus
(HAV) [RNA
Picornavirus]

Hepatitis A

Fever, jaundice,
ALT, & AST;
Asymptomatic
(Usually), Acute

Fecal-oral
(shellfish,
travelers, Day
Care)

ssRNA, (+),
Linear

Icosahedral

Good Prognosis; No Carrier


State

Hepatitis B Virus
(HBV) [DNA
Hepadnavirus]

Hepatitis B:

Fever, jaundice,
ALT, & AST;
Serum Sickness
(fever, arthralgias,
rash) Carcinoma

Parenteral, Sexual,
Perinatal

Partially
dsDNA,
Circular

Icosahedral

Yes Envelope; Not a


retrovirus, but has reverse
transcriptase; Carrier State
Common

Acute/Chronic

Terrance Garnett

Virus Pathogens List

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Summer 2016

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Herpes Simplex
Virus1

Gingivostomatitis,
Keratoconjunctivitis,
Herpes Labialis,
Herpetic Whitlow on
finger, Temporal
Lobe Encephalitis

Most individuals
infected with HSV-1
or HSV-2 are
asymptomatic or
have very mild
symptoms that go
unnoticed or are
mistaken for another
skin condition;

Respiratory
Secretions, Saliva
Infections
transmitted
through contact
with lesions,
mucosal surfaces,
genital secretions,
or oral secretions

dsDNA,
Linear

Icosahedral

Terrance Garnett

Virus Pathogens List

Most common cause of


sporadic Encephalitis;
Presents: altered mental
status, seizures, aphasia

Summer 2016
10

Herpes Simplex
Virus2

Herpes Genitalis;
Neonatal Herpes

Terrance Garnett

typically appear as
one or more vesicles
on or around the
genitals, rectum or
mouth vesicles
break and leave
painful ulcers that
may take two to four
weeks to heal; first
outbreak of herpes is
often associated
with a longer
duration of herpetic
lesions, increased
viral shedding
(making HSV
transmission more
likely) + systemic
symptoms: fever,
body aches, swollen
lymph nodes,
headache
recurrent outbreaks
are typically shorter
in duration and less
severe than the first
outbreak of genital
herpes, although the
infection can stay in
the body
indefinitely, the
number of outbreaks

Sexual Contact,
Perinatal;
Infections
transmitted
through contact
with lesions,
mucosal surfaces,
genital secretions,
or oral secretions

dsDNA,
Linear

Virus Pathogens List

Icosahedral

Latent in sacral ganglia;


Viral Meningitis (HSV-2 >
HSV-1)

Summer 2016
11

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

tends to decrease
over time,
recurrences &
subclinical shedding
are much less
frequent for genital
HSV-1 infection
than for genital
HSV-2 infection

Terrance Garnett

Virus Pathogens List

Summer 2016
12

Influenza
Influenza virus
(Orthomyxoviruses)

Terrance Garnett

Uncomplicated
influenza:
characterized by the
abrupt onset of
constitutional and
respiratory signs and
symptoms fever,
myalgia, headache,
malaise,
nonproductive
cough, sore throat,
rhinitis; (Among
children) otitis
media,
nausea/vomiting
also are commonly
reported; resolves
after 37 days for
the majority of
persons (cough +
malaise can persist
for >2 weeks);
Influenza virus
infections cause:
primary influenza
viral pneumonia;
exacerbate
underlying medical
conditions (e.g.,
pulmonary or
cardiac disease);
lead to secondary

Influenza viruses
are spread from
person to person
primarily through:
Large-particle
respiratory droplet
transmission (e.g.
person coughs or
sneezes) requires
close contact
between source
and recipient
persons (droplets
do not remain
suspended in the
air + generally
travel only less
than or equal to 1
meter through the
air); Contact with
respiratory-droplet
contaminated
surfaces; Airborne
transmission (via
small-particle
residue [less than
or equal to 5m]
of evaporated
droplets that might
remain suspended
in the air for long
periods of time)

ssRNA, (),
eight (8)
segments
genome

Virus Pathogens List

Helical

Yes Enveloped; Contain


hemagglutinin (promotes
viral entry) + neuraminidase
(promotes progeny virion
release) antigens;
Reformulated vaccine the
flu shot contains viral
strains most likely to appear
during flu season (m/b virus
rapid genetic change); Killed
Viral Vaccine + Live
Attenuated Vaccine
(administered intranasally);
Two (2) main types of
influenza (flu) virus: Types
A and B, routinely spread in
people (human influenza
viruses) + responsible for
seasonal flu epidemics each
year

Summer 2016
13

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

bacterial pneumonia,
sinusitis, or otitis
media; or contribute
to coinfections with
other viral or
bacterial pathogens
Patients at risk
for fatal bacterial
superinfection S
aureus, S
pneumonia, H

influenza

Terrance Garnett

Virus Pathogens List

Summer 2016
14

Marburg virus (see


Filoviruses)

Marburg
Hemorrhagic Fever
(Marburg HF)

Terrance Garnett

5 to 10 day
incubation: fever,
chills, headache,
myalgia;
maculopapular rash
= most prominent on
trunk (chest, back,
stomach); [Severe]
jaundice,
inflammation of the
pancreas, severe
weight loss,
delirium, shock,
liver failure, massive
hemorrhaging,
multi-organ
dysfunction

Unknown how
Marburg virus first
transmits from its
animal host to
humans, after this
initial crossover of
virus from host
animal to humans,
transmission
occurs through
person-to-person
contact direct
contact to droplets
of body fluids
from infected
persons; contact
with equipment +
other objects
contaminated with
infectious blood or
tissues; Spread of
the virus between
humans in close
environments &
direct contact =
caregivers in the
home/hospital
(nosocomial
transmission)

ssRNA, (),
Linear

Virus Pathogens List

Helical

Unique zoonotic (animalborne) RNA virus of the


filovirus family

Summer 2016
15

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Measles (rubeola)
virus
[Paramyxoviruses]

Measles

Usual Presentation:
prodromal fever (as
high as 105F),
cough, conjunctivitis
Koplik spots
(bright red spots
with blue-white
center on buccal
mucosa) (1-2
days later)
maculopapular
rash: starts at the
head/neck, spreads
downwards

Measles is one of
ssRNA, (),
Helical
the most
Linear,
contagious of all
Nonsegmented
infectious
diseases; persons
with close contact
to a measles
patient will
develop measles;
virus is transmitted
by direct contact
with infectious
droplets or by
airborne spread
when infected
person breathes,
coughs, or sneezes
Measles virus
remains infectious
in the air for up to
two (2) hours
after an infected
person leaves an
area

Terrance Garnett

Genome
Type, (+)/()
Sense,
Genome
Shape

Virus Pathogens List

Viral/Capsid Addtl Notes


Description

Morphology
Vitamin A supplementation
can reduce morbidity &
mortality from measles (i.e.
malnourished children)

Summer 2016
16

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Poliovirus
(Picornaviruses)

Polio = poliomyelitis

Sore throat, fever,


malaise. nausea,
cephalgia,
abdominal pain
(serious symptoms
that affect the brain
+ spinal cord)
Paresthesia = feeling
of pins and needles
in the legs;
Meningitis =
infection of the
covering of the
spinal cord and/or
brain; Paralysis =
cannot move parts of
the body, weakness
in the arms/legs, or
both

Enters body
through mouth &
spread through
contact with feces
of infected person,
droplets from a
sneeze or cough;
spread via fecaloral
contamination;
very contagious,
spreads through
person-to-person
contact; virus can
live in an infected
persons feces for
many weeks;
poliovirus only
infects humans

ssRNA, (+),
Linear

Icosahedral

Terrance Garnett

Virus Pathogens List

Two (2) types of vaccine


that can prevent polio:
Inactivated Poliovirus
Vaccine (IPV) + Oral
Poliovirus Vaccine (OPV);
Only IPV used in the United
States since 2000; OPV still
used throughout much of the
world

Summer 2016
17

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Rabies virus
(Rhabdoviruses)

Rabies

Progression of
disease: fever,
malaise agitation,
photophobia,
hydrophobia,
hypersalivation
paralysis, coma
death

(U.S.) Infection
more commonly
from bat, raccoon,
+ skunk bites Vs.
dog bites; Aerosol
Transmission (e.g.
via bat caves)
possible

ssRNA, (),
Linear

Bullet-shaped Travels to CNS by migrating


Virus
(retrograde fashion) up
nerve axons after binding to
ACh receptors; Negri bodies
(cytoplasmic inclusions)
commonly found in Purkinje
cells of cerebellum + in
hippocampal neurons;
Postexposure Prophylaxis:
wound cleaning +
immunization w/killed
vaccine & rabies
immunoglobulin (Passive
Active Immunity)

Rabies has long


incubation period
weeks to months
before symptom
onset

Terrance Garnett

Virus Pathogens List

Summer 2016
18

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Rhinovirus
(Picornaviruse)

common cold = acute


respiratory tract
infection (ARTI)

rhinorrhea, nasal
obstruction,
sneezing; upper
respiratory tract
may cause otitis
media + sinusitis

Viruses that cause


colds: spread from
infected people to
person via air +
close personal
contact; through
contact with stool
(poop) or
respiratory
secretions

ssRNA, (+),
Linear

Icosahedral

Nonenveloped RNA Virus;


> 100 serologic types; Acid
Labile destroyed by
stomach acid, does infect
GI tract

(when you shake


hands with
someone who has
a cold, or touch a
doorknob that has
viruses on it
then touch your
eyes, mouth, or
nose)

Terrance Garnett

Virus Pathogens List

Summer 2016
19

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Rotavirus
(Reoviruses)

Infantile
gastroenteritis

Acute Diarrhea #1
cause of fatal
diarrhea in children

Rotavirus spreads
easily among
infants and young
children both
before and after
they become sick
with diarrhea;
rotavirus shed in
feces (stool)
spreads via fecaloral route

dsRNA,
Segmented: 10
12 segments

Icosahedral
(double)

Terrance Garnett

Virus Pathogens List

No Envelope; Major cause


of acute diarrhea in U.S. in
Winter; prominent in Day
Care Centers + Kindergarten

Summer 2016
20

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Rubella virus (see


Togaviruses)

Rubella = German (3day) measles

Fever, postauricular
lymphadenopathy,
arthralgias; fine,
confluent rash that
starts on face &
spreads centrifugally
to involve trunk &
extremities

spreads when an
infected person
coughs or sneezes
may spread the
disease to others
up to one week
before the rash
appears, and
remain contagious
up to 7 days after;
can cause
miscarriage or
serious birth
defects in a
developing baby if
a woman is
infected while she
is pregnant

ssRNA, (+),
Linear

Icosahedral

Congenital Rubella:
bkueberry muffin
appearance due to
dermal
extramedullary
hematopoiesis

Terrance Garnett

Virus Pathogens List

No specific medicine to treat


Rubella or make the disease
go away fast

Summer 2016
21

Poxvirus (Variola
virus)

Smallpox; Molluscum Smallpox clinical


Contagiosum;
case definition:
Monkeypox;
Orf Virus (Sore
Mouth Infection)

Terrance Garnett

Person to Person:
dsDNA,
direct + prolonged Linear (largest
DNA virus)
An illness with acute face-to-face
contact; spread
onset of fever
through direct
>101F (38.3C)
contact with
followed by a rash
infected bodily
characterized by
fluids or
firm, deep seated
contaminated
vesicles or pustules
in the same stage of objects (bedding or
clothing); [Rarely]
development
spread by virus
without other
carried in the air
apparent cause
(acknowledging that (enclosed settings there are many other buildings, buses,
and trains)
causes of vesicular
Humans only
and pustular rash
illnesses) Healthcare natural hosts of
providers evaluating variola, Smallpox
is not known to be
cases should
transmitted by
familiarize
insects or animals
themselves with
diseases that can be
confused with
smallpox: varicella,
herpes simplex, drug
reactions, erythema
multiforme

Virus Pathogens List

Complex
brick or ovalshaped

Smallpox eradicated
worldwide by use of the
live-attenuated vaccine;
Cowpox (milkmaid
blisters); Yes Envelope;
DNA-dependent RNA
polymerase

Summer 2016
22

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Varicella-Zoster
(HHV-3;
Herpesvirus; HZV)

Varicella-zoster
(chickenpox,
shingles),
Encephalitis,
Pneumonia

Rash itchy, fluidfilled Blisters


Scabs (Chickenpox
illness usually lasts
about 5 to7 days)
fever, tiredness, loss
of appetite,
headache [serious
complications]
bacterial infections,
pneumonia, bleeding
problems, sepsis

Respiratory
Secretions enters
respiratory tract &
conjunctiva
primary viremia
occurs 4 to 6 days
after infection,
disseminates the
virus to other
organs: liver,
spleen, sensory
ganglia;
respiratory contact
with airborne
droplets or by
direct
contact/inhalation
of aerosols from
vesicular fluid of
skin lesions of
acute varicella or
zoster

dsDNA, (+)
Linear

Icosahedral

Terrance Garnett

Virus Pathogens List

Most common complication


of Shingles = post-herpetic
neuralgia; Latent in dorsal
root or trigeminal ganglia;
Varicella zoster virus
polymerase chain reaction
(PCR) = method of choice
for diagnosis of varicella

Summer 2016
23

Pathogen

Disease Name(s)

S/S of Disease

Acquire Infection

Genome
Type, (+)/()
Sense,
Genome
Shape

Viral/Capsid Addtl Notes


Description

Morphology

Flaviviruses
(Arbovirus)

Yellow Fever

High Fever, Black


Vomitus, Jaundice

Transmitted by
Aedes mosquitoes;
monkey or human
reservoir

ssRNA, (+),
Linear

Icosahedral

Terrance Garnett

Virus Pathogens List

Flavi = yellow, jaundice;


may see Councilman bodies
(eosinophilic apoptotic
globules) on liver

Summer 2016
24

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