Blood

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Variation
W.
By
HE
W.
aid
an
therefore
in
adequate
Altitude
levels
the
tiot
from
of
Canada,
the
reliable
considered
as
have
a factor
l)eems
100
the
years
of
United
to
age
older
people
States,
justify
the
particularly
before
among
older
levels
the
these
tables
magmsitude
A
are,
reported
levels
United
obtain
hetweems
with
adults.
middle
Smh
people
data
age,
The
N.
of
the
Ofl
1308
male
other
between
Regional
AND
and 1424
November
reported
tens years,
The
values
methods
with
ose
typical
of those
usually
adult
life. The other
lower.
but
women
The
sex
it is smaller
the
its
upon
is little
people
treisd
its reports
or no
a decrease
of
of
the
(hausge
its
occurs
in
the
to
allow
degree
comparisoms
of the
of
sex differemsce
be of fairly
side interest
amsd use,
likely
to exist
hetween
hemoglobin
in many
other
localities
in Camsada,
coumstries,
particularly
at sea
level.
METHODS
feussale
12,
Laboratory,
last
subjects
1952,
anstl
National
bet weeu
May
22,
Research
tlue
ages
1953.
The
Council
of
9,
1954.
of
Canada,
98
arutl
youngest
subIlali-
S.
Submitted
We
these
that
but
adult
could
some
beets
the
cots-
in order
to extend
informatious
our
6 years
of age upw-ard.
We wished
would not be
Halifax
amsd those
amid possibly
Maritime
age,
on
SUBJECTS
From
of
hemoglobin
have
geuserally
and
amid to itidicate
information
differemsces
States,
aspect
is kmsowus
l)y Wiustrohe,
mets
advaisciusg
sufficient
The survey
was (lone
years. It was carried out
fax,
showus
here was umidertakems

of individuals
from
amid after
significant
among
the
is
be comssurveys
ots this
Britaims.
of
however,
as that
differemsce
of women
to
values
because
same
people.
The work
hemoglobin
must
have
Little
amid Great
comparisoms
values
in late adult
life has been
remarked
years.
Evidence
has beets provided
that
there
the hemoglobin
men.46
used
l)asis
its relatioms
states
decade
withims
mostly
in
hemoglobin
last few
values
factors.
which
values
among
is widely
affectimsg
domse.1
reported
in this
survey.
values
givems by Wintrohe2
are
of mets amid womems throughout
adult
Sex
factual
figures
and with those

Its tables
2 amsd 3 the
coissidered
as characteristic
is of the
blood
A sound
of other
geographic
hemoglobims
values
similar
another
for
LEONARD
whets
borderlimse
omsly about
the last
surveys
4 to about
sufficiently
difference
G.
of hemoglobims
to provide
he
most
importamsce
3 summarize
from
were
and
VERNA
of health.
tremsd
important
Within
amid exteist
where
particularly
the
Age
respect
childreus
from
six years
of age upward
amsd young
most
attemstion.
The state
of kmsowledge
con(ermsiusg
Isemopopulatioms
groups
is, however,
still umssatisfactory.
possible
1 2, and
individuals
AND
state
establishimig
useed
localities
cerising
Tables
of the
is most
surveys.
probably
in
used
for
in number
have
levels
SPECK
with
CONCENTI(ATH)N
Its this
received
in some
hematology.
Level
EIaLY5
assessmetst
and sex. This

as in msutritiots
women
globin
Hemoglobin
HAWKINS,
necessary
to age
sidered,
for
the
HEMOGLI)BIN
as
been
of
must
course
December
thank
of this
Dr.
survey,
9,
E.
1953;
Gordon
and
accepted
Vounug,
for hell)
for
the
publication
Director
ins preparing
999
February
of this
the
nsaterial
Laboratory,
for
for publications.
ativice
dun
rig
1000
VARIATION
TAB
Age
No.
OF
hEMOGLOBIN
I.E
1 -Hemoglobin
of subjects
Hgb
(hildren
av.)
Locality
Ref.
13.3-13.6
Great
Britain
19
13.2
Great
Britain
20
1483
12.8
British
5-il
3575
1456
12.8
13.3
Floritia
Saskatchewan
5-15
200
12.5
hamilton,
5-16
518
12.4
East
8-13
515
13.1
Louisiana
Columbia
14
12
15
Ont.
10
Ont.
York,
10
21
7-14
358
13.5
Michigans
7-14
1669
13.6
Saskatoons,
S
Sask.
297
h)oys
13. 1-13.8
Eniglanud
13
10
329
boys
13.5-14.0
England
13
14
550
boys
14.3-14.7
Enugland
13
2.-Hemoglobin
TABLE
Age
No.
of subjects
Hgb
Levels
%,
(Gm.
among
as.)
Men
Locatity
Ref.
19
12-19
13.8
Great
Britaini
15-19
14.2
Great
Britains
19
16-25
137
15.1
Hawaii
22
111
15.8
Cleveland
23
25
15.9
Philadelphia
24
411
15.2
Bostons
25
77
16.2
Sydnsev
26
51
17-23
17-25
19-28
15.6
Norway
539
245
16.0
15.7
U. S. A. and
Great
Britain
175
16.0
Lima
28
60
13.8
Canada
11
330
14.0
Winunsipeg
60-94
50
14.1
St.
60-98
41
13.9
Scotlansd
65-80
73
13.1
U. S. A.
29
69-91
50
12.6
U.
S.
A.
30
160
14.3
U.
S.
A.
31
19-30
16-59
50-79
50-97
60-104
jects
were
ins tlse
studied
during
the
early
part
of the
winter,
27
Europe
2, 3
13
Louis
5
4
and
the
adults
later
in the
winter
and
sprinsg.
the
With
provide
drawn
help
of the
children
from
each
Those
from
universities,
to
Halifax
14 to
was
with
disorders
folks
homes.
welfare
class
2() years
Capillary
into
of
Service,
a variety
were
age
the oldest
schools
its high
studensts
among
six
were
of socio-econsomic
them
schools,
would
wisich
would
Subjects
hospitals,
expected
be
choseni
groups.
to have
were
colleges,
and
a better
than
background.
wide variety
likely
Many
groups.
than
Medical
old from
in each school.
at least
socio-economic
There
School
14 years
grade
so that
average
taken
SEX
493
known
%,
(Gm.
a many
AND
nomic
Levels
AGE
4-14
old
WITH
6-13
6-14
anuy
LEVEL
those
blood
a calibrates!
from
of adult
to
were
affect
members
Ins general
usually
the
pipet,
adults
of the
finger
collected
were
some
were
and
were
ins surveys
and
There
hemoglobins
of clubs
studied
a puncture
Sahli
subjects.
the
societies,
more
of this
tip
was
ins a few
invalids
excluded.
among
Some
including
healthy
them,
were
some
and
but
residents
of
in a better
the
of
better
socio-eco-
kind.
used.
A sample
nmilliliters
of 20 cu.
of water
mm.
was
in a test
tube
HAWKINS,
No.
of subjects
A ND
Hgb
Ierels
%,
tGm.
1001
LEOXA
liD
among
hlonuen
Locality
av.)
Ref.
12-19
12.8
Great
Britaits
19
15-19
13.6
Great
Britain
19
32
12-19
258
12.2
13.0
15-22
48
44
Mi nsnsesot a
Cleveland
13.6
iIi55iS5il)l)i
17-21
1080
12.0
Toronto
17-24
4550
13.4
Nortlu
23
33
central
17-22
161
13.8
Amherst,
17-25
52
13.2
Linscolns,
17-26
352
13.8
Saskatoon,
18-23
25
13.5
Philatlelphia
17-68
403
14.0
U.
19-30
U.
S.
10
34
A.
Mass.
S.
35
Neb.
36
Sask.
24
A.
ansd
2, 3
Europe
14.1
Norway
275
13.2
Lincoln,
480
13.8
Great
64
12.7
Cansada
175
13.6
60-90
50
13.7
60-98
48
13.2
Winnipeg
St. Louis
Scotland
65-80
27
12.5
U.S.
A.
29
66-104
50
11.7
U. S.
A.
30
60
17-86
50-79
50-97
marked
to the
at
10 ml.
10 ml.
At the
nsark
mination
of
laboratory
with
spectrophotometer.
the
K,
3.-Hemoglobin
TABLE
Age
SPEC
water,
This
the
was
described
had
Collier.7
been
36
Britains
13
11
6
5
4
with
(lensity
of the
by
concentration
treated
optical
is ans application
hemoglobin
hemoglobin
this
arid
27
XCI).
ferricvanide
and
at 540
mM in a Coleman
read
cyanmethemoglobins
It
was
method
standardized
determinetl
cyanide,
from
against
the
iron
for
ea(h
diluted
model
for
the
blood
constent
14
deter-
of which
and
oxygen
capacity.
RESULTS
The
hemoglobin
in table
values
4 and
Among
figure
the
average
children
of about
Gm. among
for higher
arrausged
accordiisg
to age
6 to
13 Gm.
the oldest.
values
to
14 years
per
old
100 ml.
Up to about
occur
amoisg
amomig the boys.

The average
was the same,
13.5 Gm. per
values
imscreased
amomsg
12 years of age
the girls,
hut
value
100
the
of blood
the
there
cent
of
and
28 per
the
tendency
In
the
creased
In the
at
jects.
14
them
were
cent
lower.
subjects
latter
years,
In
betweems
toward
slightly
amid
individuals
No
after
betweels
represented
girls,
value
slight
with
14 amid
the
average
this
values
20
positive
increasimsg
preseusted
years
of age
rather
at 20 years
of age
of age
the
that
from
an
to about
14
a temsdeuscy
they
were
higher
6 to 14 years
to msote that
of age
many
Ams examimsation
of age.
childrems
showed
ceust
of them
skewness
was
the
that
beiusg
40
higher
a reflectioms
hemoglohims
markedly
was
highest
iusclusive,
age
of
age.
amsd increased
essemitially
15 to 20 years
31 per
14 Gm.,
ausd
with
youusgest
for both
boys amsd girls
ml. It may
be of itsterest
13
doubt
higher
among
the
are
was possibly
of the girls had started

to memsstruate
at about
11 years
of the distribution of hemoglohins
values
amomsg
these
per
sex
1.
5 per
cent
value
the
average
values
amomsg
the
higher
shown
by
deboys.
thams that
male
hemoglobius
suls-
value
1002
VARIATION
OF
4.-laria(ion
TABLE
HEMOGLOBIN
of Hemoqiobin
LEVEL
Levels
Population
with
WITH
.lge
of
AGE
and
Sex
AND
among
Representatives
Hgb.
Females
per
100 ml. of blood)

_______
________
(Gm.
No. of
subjects
Range
As.
S.D.
per
tOO ml.
of blood)
_______________
Range
A.
S.D.
66
11.3-14.8
12.5
0.81
53
11.4-14.7
13.2
0.69
45
10.7-14.5
13.1
0.91
60
11.4-15.3
13.2
0.89
55
11.2-15.1
13.3
0.91
42
11.1-15.7
45
11.9-15.1
13.5
0.80
60
11.2-15.7
10
78
11.8-16.0
13.5
0.81
62
11.7-15.2
11
56
11.4-15.3
13.4
0.91
57
11.6-17.0
12
51
12.0-16.4
14.1
1.01
56
11.5-15.9
13
45
12.2-15.8
14.0
0.91
66
11.3-15.4
14
66
12.2-16.5
14.3
1.12
93
11.4-16.3
13.1
0.99
13.4
0.92
13.3
0.90
13.7
1.15
13.7
0.79
13.7
0.87
13.5
1.07
15
lOt)
11.4-17.4
14.4
1.05
154
10.5-15.7
13.3
0.9S
16
119
11.7-17.5
14.5
1.13
169
8.0-15.9
13.0
0.98
17
18
83
52
11.1-17.1
12.8-16.9
14.8
15.0
1.17
1.05
104
7.4-15.3
13.2
1.13
10.6-15.4
12.9
0.82
19
39
12.8-16.5
14.9
0.96
44
10.3-14.3
12.5
0.87
20
11)
12.8-17.5
14.9
1.05
21
11.3-14.1
13.2
0.75
57
21-30
83
12.1-18.0
15.1
1.22
44
9.0-14.4
12.7
1.14
31-40
23
12.3-17.5
14.6
1.35
39
11.0-16.2
13.2
0.92
41-50
23
11.8-16.8
14.7
1.26
39
10.2-16.5
13.2
1.30
51-60
65
8.1-16.9
14.4
1.31
41
9.6-16.3
13.1
1.32
61-70
51
8.4-17.4
13.9
1.59
55
7.7-15.6
12.9
1.33
71-80
71
81-90
28
8.9-17.1
8.9-15.8
13.4
12.4
1.59
1.73
71
33
8.3-16.1
11.1-15.4
13.0
13.0
1.45
1.24
91-100
8.9-14.3
11.2
2.18
10.6-12.6
11.4
0.95
6-14
510
10.7-16.5
13.5
1.00
549
11.1-17.0
13.5
0.96
15-20
421
11.1-17.5
14.6
1.12
549
7.4-16.3
13.2
1.04
326
8.3-16.5
13.0
1.20
1424
7.4-17.0
377
8.1-18.0
14.1
1.65
6-94
6-98
for
males
per
cemit.
of the
1308
16
Gm.;
ceist
and
Its the
13.0
and
was
14.6
distributions
had
99
per
case
Gm.
ceust
thereafter
its
het.weeui
of the
of
arid
for females
also
reflected
12 amid
females
amsy
its
age
for
very
little.
decade
succeedimsg
13.2
the
Gm.,
17
had
amid
levels
Gm.,
sex
81
a differetsce
differemsce
per
of 10
: 98 per
ceist
between
13 amid
16 Gm.,
and
of 14.1 Gm.
the values
in
tables
cent
10 and
between
of age the
be compared
ratsges
those
its youmsger
third
1.07
93
15 Gm.
Gm.
12.7
showus
differed
or
ml.,
100
13.3
1.23
of values
differemsces
ins the
those
14.0
of those
above
20 years
for women
cams hardly
because
those
per
11 ausd
value
of
Gm.
levels
betweens
average
8.1-18.0
The
males
per
group
(Gm.
___________
21-98
for
Hgb.
No. of
subjects
21-94
ansy
of the
Halifax
Males
Age
SEX
are
its the
yearly
Amotsg
was
decade.
higher
insvolved.
third
age
the
averages
with
decade
groups.
mets
the
thami
Decreases
Among
that
the
of life
was
The
averages
average
value
men
2
women
the
lower
than
for decades
of 15.1 Gm.
its amsy youmiger

its hemoglobits
for
yearly
values
age
among
HAWKINS,
SPECK,
AND
LEONARD
1003
a
0
17
16
P4.1.
Av.S.D
F.sI.
#{149}
II 1IF
flifflh1fl
j;
10
#{149}
10 II
1213
14
1516
17181920
2l..3O3l..4O415O5I-6O6I..7O7I-8O81-9O
AGE
FIG.
-The
rensd
population
of Halifax.
the
were
meis
men
values
of age,
amomsg
amsd 15 Gm.
Its womeis
per
they
values
those
and
mets
temided
became
amid
among
the
fifth
up
womemi
much
those
of age
at ives
of
decade.
to
smaller,
thaus
60 years
represerut
hue
slsowns.
after
amousg
to be lower
20
sex
are
marked
thams
differemices
l)etw-eems
arud
tleviatiotss
more
highem
the
its mets
wit hi age
stanutiard
amsd
comssiderahly
thereafter
values
ansd
progressive
values
globimi
values
Averages
were
1)1St
decade
of hemoglol)inu
amid
amousg
were
Amousg
about
70
its
vomeus.
typi(ally
years
tise
tsimstls
Hemo-
l)etweeus
14.3
100 ml., the higher

values
occurriung
amomsg the youmsger
sul)jects.
were
typically
about
13
Gm.
The
differeusce
l)etweeus
these
ims tables
2 amid 3 are greater
its the
case
of mets than
of womeus.
DiscUssIoN
The
average
childrems
age
group.
these
A tremid
14 years
Our
ages
vestigatiomss
from
hemoglobin
6 to
results
the
of
value
old
is among
agree
hemoglobin
13.5
the
with
some
imicreases
have
imsdicated
toward
higher
values
(.m.
highest
100
13
its
to
iuscrease
its l)oys
14
6 to
Pett,
Hanley,
amid
a group
those
which
Hanley5
Perkimss1m
of over
fell
below
deduced
of
children
intervals
children
total
of
oms the
1)asis
a thousatid
11.9
the
same
5 to
11
Gm.
per
value
years
of the
childmeis
100
as the
old
its
iii
iusdicatimig
that
per
age,
14 yeams
but
old
100
fom this
betweems
ml.
Other
lower
has
Flalifax
for
reported
of
999
(10.7
ims a histogram.
each
bar
of
the
Gm.
for
curve
amid
disttibutiomi
British
its-
\.ttlIl(s
l)eets
#{176}-
reported
represeust.
Iowei
limit
of normal
was
extemsded
Our
were
two
Gm.
drawus
to
suggested
from
data
one
through
the
axis
time
the
ots
Halifax
six
omitted
girl).
which
amsd
examimsa-
the
ots
that
Pett
among
extremes
for
is im-
j)( made.
values
amsemia.
distributed
the
17.0
(,lsildrems
ma\!
of hemoglobius
could
amid
in
Columbia,
Saskatchewams.
omse boy
A smooth
diagram,
ausemia
speculatiomss
ml.
were analyzed
as follows.
The values
fallimsg hetweems
12 and
17 Cm.,
with
arranged
top
l)lood
England.13
amomig
the
of
beets
Gm.
with
The questioms
of what
lsemoglobims
level represemsts
port.amst.
Aim amsswer
is of course
tsot possii)le,
but
tioms
ml.
have
others2
fmom
the same
thams ours
rem
which
class
out
They
middle
the
of
were
of the
hemo-
1004
globin
VARIATION
OF
were
represemited.
values
Its limits
were
raisge
of values
would
12 arid
LEVEL
This
appear
to
15 Gm.
This
insformatiomi
average
hemoglobims
might
were
vere
in
AND
a slight
which
who
use
however,
per 100
AGE
showed
Gm.,
h)e of little
distributioms
was such,
levels
below
12 Gm.
WITH
curve
at 11.1 Gm. amid 16.8

among
the 997 subjects
therefore
level.
The
hemoglobims
hEMOGLOBIN
SEX
positive
skewness.
also
the
limits
of the
a procedure
to
defimie
Such
comssidered.
attempt
an
that
5 per
ml. of blood,
be of more
the
anemic
cemit of the childrems

had
aisd 87 per cent between
use
thiuskiisg
iii
about
amsemic
levels.
The
womems
for
14 to 20 years
young
showms
girls
as young
toward
as
14,
arid
decrease
other
ralues
surveys.1
which
10.
each decade
of life
indicatimig
a virtual
many
of
value
mets,
betweems
leveliisg
groups
to be high compared
males
its this period
Halifax
subjects
the same
25
years
The
old
the
average
showed
13.9
iiscreases
Gm.
was
value
Youmsg
the
mens
globin
value
which
was
Its the
The
levels.
The
this
by
value
Pet.t
of
those
group
subjects,
were
in
small
degree
100
Gm.
its
authors
Halifax
a leveling
but
ml.
that
aisd
figures
of vamiatioms
20 years of age was remarkable.
of age
its males
amid
however,
might
be
its hemoglobin
per
same
in
years
to 30.
old
This
its amsy decade
of life.
average
hemo-
as that
values
hemoglobirs
values,
ramiged betweems
14.2 Gm.
for the
per
cent
proportioms
among
highest values amomsg
to
last
20s.
the
attempts
ml.
100
subjects
14
20
highest
95 amid 100
of use
values
amid increases
this
group
of
Gm.
to
imito the
inclusive,
the
Halifax
essemstially the same
deviatioms,
12.2 amid
betweels
over,
The
13
from
maimstaimsed
off
reported
Catsadian
mcmi
it was
for
of those
14.9
the
in
100 ml.,
by Pett
with
those
of more
that
for those
17 to
amousg
showed
noted
womemi
Gm. per
obtained
of age,
irs boys
foumsd
also
decrease
been
of blood
higher,
youmsg
compare
has
most
is a
1)etween
Halifax
ml.
years
there
The
imsdicated
than
Ogilvietm
13.2
Gm.
15 to 20 years
so distributed
12 Gm. per 100

arid over.
These
group
also
lower
was
and
as mimsus arid plus one standard

per 100 ml. for the males,
amid
values
age
If
would
amotsg
per
20.
range.
were
12.7 to 13.2
age of 20. Values
20 to 30
of army of the male

subjects,
at the age of 17 arid
Halifax
age
compare
more
favorably
is supported
by the fact
amid 14.5
which
age
young
values
womeis
to those
in the five precedimsg
years,
of life would
be expected,
so that
reached
expressed
15.7 Gm.
showed
10 Gm.
highest
ins
this
of Camsada
From
thams
subjects
same
values
was
19,
for
of average
young
Halifax
Cm.
2).
of blood
older
in
the
withims
parts
ams average
17 to
these
msearly
of 14.6
found
from
in those
for
hemoglobims
values
some
values
hemoglobims
proh)ab)ly
would
age ramige. This
hemoglobims
ramsge
of age imsclusive,
(table
tended
amotsg
nearly
ml.
the
20 amid 90 years
off at about
the
15 to 20 years
cOmparal)le
015
100
we observed
and Ogilvie#{176} omi womems in various

through
the middle
years
of life.
The average
hemoglobims
value
youlsg
Gm.
imiclude
its more
Average
11
per
was withims
hemoglobims
those
ages,
thems the average
favorably
with those
for others
its hemoglobins
13.2
Umsited
States,
amid Great
Britain
svhich
are
comparable
groups
represemsted
in this table
table
tendeiscy
in
of
its Halifax
womems its Camsada,

the
3. Very
few of the
its
include
value
of age
women
females
the
define
and
females.
of the
of
to
13.5
males
females
ansemic
after
about
were
shown
SPECK,
HAWKINS,
AND
by those
between
10 and 14 years
of age.
pause
affected
the hemoglobin
level.
In men the progressive
resulted
in the highest
were
30
50,
then
hemoglobin
appeared
values
This
surveys46
which
supplies
between
have
further
Whether
may
the
higher
followed
by a fall,
values.
men
been
evidence
or not
to note that
in the liver,
was
decreasimig
amid
to be the result
of decreasing
men
after
middle
age has
in
this
was
progressively
values
There
1005
iso evidemice
that
the
memso-
increase
ims hemoglobin
through
childhood
amid youth
values
beimig showms in the 20s, whets the lowest
values
by women.
shown
and
LEONARD
it has
The
womems
to above,
a levelimsg
off betweems
decreasimsg
with
differemice
advamscimsg
levels
in men.
beers irsdicated
referred
for
possibly
age
imi
therefore
This trend
its hemoglohims
the results
of previous
in
amid the
material
of this
report
it.
any
connection
with
hemoglobin,
it might
be of iusterest
there
is a difference
between
the sexes in the (omiceustratioms
of iromi
but it varies
with the species.tm6
In rats it is higher
ins females,
and
be
associated
liver
with
sex
hormonses.mt
17
In the
case
of humauss,
mets
have
iron.8
SuIIAIsY
During
the winter
and spring
of 1952-53
made
in Halifax
among
1308 male subjects
6 to 94 years
of age.
Among
children
6 to 14 years
old the
14 Gm. per 100 ml. of blood,
and there
a survey
of hemoglobims
values
was
6 to 98 years
of age, amid 1424 female
subjects
the
sexes.
In
The
girls
slightly,
average
between
reaching
was
au
20 years
They
were
female
to
of age,
the
20
13 Gm.
about
the
of
per
100
In
lowest
subjects
itscreased
essentially
boys
amid the
sexes
these
characteristic
arid
from about
13 to about
rio differemsces
between
girls
was
13.5
Cm.
age the hemoglobims

values
ml. In boys of correspomsdimsg
both
remaimied
the
male
both
years
15 Gm.
and
essentially
and
for
and
about
increase
about
value
14
values
were
the
of army age
highest
values
were
of the
third
showms
respectively
decreased
ages there
attaimsed
decade
at
of life.
h)y
the
group.
Hemoglobin
values in mcmi between
20 arid 60 years of age were typically
to 15 Gm. per 100 ml., the higher
values
tensdimsg
to occur
amouig
the youusger
men.
After
the fifth decade
there
were progressive
amid marked
decreases
to ami
14.5
average
In
of 12.4
women
mained
in men
20
between
years
from
near
13 Gm.
per
80 arid
of
100
age
presentate
un
studio
of age.
the
average
hemoglobins
values
re-
ml.
SUMMARIO
Es
90 years
onsward
IN
del
statistic
INTERLINGUA
valores
hemoglobinic
obtenite
durante
le
e primavera
de 1952/53 a Halifax in Nova Scotia ab 2732 individuos1308 masculin
de etates
ab 6 a 98 annos
e 1424 feminin de etates ab 6 a 94 annos.
In juvenes
inter
6 e 14 annos
le valores
cresceva
ab circa
13 a cim(a 14 g per
hiberno
100
ml
de sanguine.
constatate
In
In iste gruppo
de
le sexos.
Le valor
medic
inter
14 e 20 annos
deetate
inter
pueras
levemente
usque
a circa
13 g per
100 ml
etate
nulle
pro pueros
le valores
de
sanguine.
differentia
essential
e pueras
esseva
de hemoglobina
In pueros del
esseva
13,5
g.
decresceva
mesme
etates
1006
VARIATION
ii habeva
un
attingite
del
HEMOGLOBIN
accrescimento
usque
de circa
20 annos.
a! etate
vita
OF
e representava
LEVEL
15 g.
Illos
respectivemente
WITH
In
AGE
ambe
AND
sexos
SEX
iste
remaneva
typic
durante
le minimo
e Ic maximo
valores
esseva
le tertie
decade
inter
le gruppos
de etate del duo sexos.

Le
valores
de hemoglobina
14,5 a 15 g per
typicamente
occurrer
le individuos
in
in masculos
100
plus
ml
de
juvene.
inter
30
sanguine.
Post.
e 60
Le
le quimste
e marcate
decrescimentos
usque
al valor medic
de etate.
In feminas
post 20 annos
de etate
Ic valores
annos
valores
decade
de
12,4
de
plus
etate
alte
il habeva
pro
esseva
tendeva
progressive
homines
inter
80 e 90
annos
presso
a 13 g per
medic
de hemoglobina
persisteva
100 ml de sanguine.
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W.
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W.
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M.,
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62:
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763,
AND
S.
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ANL)
M.
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E.
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R.
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Variation of the Hemoglobin Level with Age and Sex

W. W. HAWKINS, EIRLYS SPECK and VERNA G. LEONARD
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From www.bloodjournal.org by guest on September 24, 2016. For personal use only.

here was umidertakems

and with those

and sex. This

amomig the boys.

of the girls had started

100 ml. of blood)

its amsy youmiger

100 ml., the higher

at 11.1 Gm. amid 16.8

cemit of the childrems

20 years of age was remarkable.

its amsy decade

highest values amomsg

essemstially the same

12 Gm. per 100

as mimsus arid plus one standard

of army of the male

and Ogilvie#{176} omi womems in various

womems its Camsada,

age the hemoglobims

de etate del duo sexos.

L.: Urue vielle tlonns#{233}e

A. J. 50: 550, 1944.

24: 502, 1939.

Variation of the Hemoglobin Level with Age and Sex

Updated information and services can be found at:

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