discharged (Payment in due course causes the discharge of the person primarily liable): 1. Upon payment by the person primarily liable on or after date of maturity without knowledge of any defect. 2. Payment by agent of the principal debtor made in payment in due course. 3. Payment by an accommodated party. - The party accommodated is really the person indebted. He is ought to be liable to the instrument. The accommodation party only lends his name. Thus, deemed to be made by the person primarily liable. 4. If instrument is cancelled and destroyed. Discharge in negotiable instrument doesnt mean cancellation. It means it ceases to be negotiable. Hence, the release of all persons liable to the instrument, both primarily and secondarily; due to cessation of negotiability of the instrument. So already unenforceable. When can the cancellation cause the discharge of the instrument?