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NCPF

base units according to the algebraic relationships linking

the corresponding quantities. Some of these derived units

have special names and symbols. The SI units used in the

European Pharmacopoeia are shown in Table 1.6-2.

London School of Hygiene and Tropical

Medicine

Keppel Street

London WC1E 7HT, Great Britain

National Collection of Type Cultures

Central Public Health Laboratory

Colindale Avenue

London NW9 5HT, Great Britain

National Collection of Yeast Cultures

AFRC Food Research Institute

Colney Lane

Norwich NR4 7UA, Great Britain

Statens Serum Institut

80 Amager Boulevard, Copenhagen,

Denmark

NCTC

NCYC

S.S.I.

International System are shown in Table 1.6-3.

The prefixes shown in Table 1.6-4 are used to form the names

and symbols of the decimal multiples and submultiples of

SI units.

NOTES

1. In the Pharmacopoeia, the Celsius temperature is used

(symbol t). This is defined by the equation :

centigrade temperature is expressed in degree Celsius

(symbol C). The unit degree Celsius is equal to the unit

kelvin.

2. The practical expressions of concentrations used in the

Pharmacopoeia are defined in the General Notices.

01/2005:10600

SYSTEM (SI) USED IN THE

PHARMACOPOEIA AND

EQUIVALENCE WITH OTHER UNITS

INTERNATIONAL SYSTEM OF UNITS (SI)

The International System of Units comprises 3 classes of units,

namely base units, derived units and supplementary units(1).

The base units and their definitions are set out in Table 1.6-1.

which cut off on the circumference an arc equal in length

to the radius.

4. In the Pharmacopoeia, conditions of centrifugation are

defined by reference to the acceleration due to gravity (g) :

Pharmacopoeia : relative density (2.2.5), absorbance

(2.2.25), specific absorbance (2.2.25) and refractive index

(2.2.6).

6. The microkatal is defined as the enzymic activity which,

under defined conditions, produces the transformation

(e.g. hydrolysis) of 1 micromole of the substrate per

second.

Unit

Quantity

Definition

Name

Symbol

Name

Symbol

Length

metre

The metre is the length of the path travelled by light in a vacuum during a time

interval of 1/299 792 458 of a second.

Mass

kilogram

kg

The kilogram is equal to the mass of the international prototype of the kilogram.

Time

second

Electric current

ampere

The ampere is that constant current which, maintained in two straight parallel

conductors of infinite length, of negligible circular cross-section and placed

1 metre apart in vacuum would produce between these conductors a force equal to

2 10 7 newton per metre of length.

Thermodynamic

temperature

kelvin

triple point of water.

Amount of substance

mole

mol

entities as there are atoms in 0.012 kilogram of carbon-12*.

Luminous intensity

Iv

candela

cd

monochromatic radiation with a frequency of 540 1012 hertz and whose energy

intensity in that direction is 1/683 watt per steradian.

The second is the duration of 9 192 631 770 periods of the radiation corresponding

to the transition between the two hyperfine levels of the ground state of the

caesium-133 atom.

* When the mole is used, the elementary entities must be specified and may be atoms, molecules, ions, electrons, other particles or specified groups of

such particles.

(1) The definitions of the units used in the International System are given in the booklet Le Systme International dUnits (SI) published by the Bureau International des Poids et

Mesures, Pavillon de Breteuil, F-92310 Svres.

10

Table 1.6.-2. SI units used in the European Pharmacopoeia and equivalence with other units

Unit

Quantity

base units

SI units

m 1

Name

Symbol

Name

Symbol

Wave number

1/m

Wavelength

m

nm

Area

A, S

micrometre

nanometre

square metre

m2

10 6m

10 9m

m2

Volume

cubic metre

m3

m3

Frequency

hertz

Hz

s 1

Density

metre

kg/m3

kgm 3

Velocity

m/s

ms 1

Force

newton

mkgs 2

Pressure

pascal

Pa

m 1kgs 2

Nm 2

1 dyne/cm2 = 10 1 Pa = 10 1 Nm 2

1 atm = 101 325 Pa = 101.325 kPa

1 bar = 105 Pa = 0.1 MPa

1 mm Hg = 133.322 387 Pa

1 Torr = 133.322 368 Pa

1 psi = 6.894 757 kPa

Dynamic

viscosity

pascal second

Pas

m 1kgs 1

Nsm 2

1 P = 10 1 Pas = 10 1 Nsm 2

1 cP = 1 mPas

Kinematic

viscosity

second

m2/s

m2s 1

Pasm3kg 1

Nmskg 1

1 St = 1 cm2s 1 = 10 4 m2s 1

Energy

joule

m2kgs 2

Nm

Power

Radiant flux

watt

m2kgs 3

Nms 1

Js 1

1 erg/s = 1 dynecms 1 =

10 7 W = 10 7 Nms 1 =

10 7 Js 1

Absorbed dose

(of radiant

energy)

gray

Gy

m2s 2

Jkg 1

1 rad = 10 2 Gy

Electric

potential,

electromotive

force

volt

m2 kgs 3A 1

WA 1

Electric

resistance

ohm

m2 kgs 3A 2

VA 1

Quantity of

electricity

coulomb

As

Activity of a

radionuclide

becquerel

Bq

s 1

Concentration

(of amount of

substance),

molar

concentration

metre

mol/m3

molm 3

Mass

concentration

metre

kg/m3

kgm 3

Unit

Quantity

Value in SI units

Time

Symbol

minute

min

1 min = 60 s

hour

1 h = 60 min = 3600 s

day

1 d = 24 h = 86 400 s

Plan angle

degree

1 = (/180) rad

Volume

litre

1 l = 1 dm3 = 10 3 m3

Mass

tonne

1 t = 103 kg

Rotational

frequency

revolution

per minute

r/min

1 r/min = (1/60) s 1

Time

1 ml = 1 cm3 = 10 6 m3

1 dyne = 1 gcms 2 = 10 5 N

1 kp = 9.806 65 N

1 erg = 1 cm2gs 2 =

1 dynecm = 10 7 J

1 cal = 4.1868 J

1 Ci = 37109 Bq = 37109 s 1

Factor

Prefix

Prefix

Symbol

10

deci

10

centi

10 3

milli

10

micro

nano

exa

15

peta

1012

tera

10

10

Factor

1

Symbol

18

10

giga

10

mega

10

10

kilo

10 12

pico

hecto

10 15

femto

atto

102

10

deca

da

10

18

11

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