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Disorders)
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Temple Grandin ted talk has autism. Thinks in piuctures and videos rather
than words
o Normal IQ
o Often have normal to advanced language form and content (not
use/sociopragmatics)
o Specialized interests
o Catatonic- movement is hard , sometimes stiffness,
o Onset in early development but may become apparent only when
social demands increase
Speech sound disorders (not structural e.g. cleft palate, due to hearing
loss, selective mutism or dysarthria)
o Language disorders (receptive, expressive, mixed
o ADHD
o Intellectual disability
o Fluency disorders
o Social phobia
o 3 or 4:1 boys to girls, Dramatic increase in diagnosis in last ten years
o Usually associated (co-morbidity) ADHD , ADD, or anxiety .
Potential causes
o Genetic male 3X more than female, pre-puberty Associated with
serotonin, oxytocin production
o Neurological component,
Abnormal regulation of brain growth in autism results in early
overgrowth followed by abnormally slow growth
Overgrowth of white matter compared to grey matter with
differences in connectivity between the hemispheres and
cortical areas within each hemisphere
Damage to the prefrontal cortex, limbic regions and brainstem
Cerebellar deficits (loss of neurons early in development)
Increased cell density (nerve cells not pruned back as happens
in typical brain development)
Excess dopamine
Abnormal connectivity between brain cells responsible for
imitation, facial expression and sensory processing
Atypical development of mirror neurons
Evidence of autoimmune processes affecting brain development
o course of development S
seizures
Difficult delivery
Delayed breathing
o environmental influence : prenatal or pesticides, antdepresent, or
chemicals, age of mother, high stress, older father Testosterone,
Alcohol, Infections e.g. Rubella, CMV, environmental pollution
start with moter difference
o