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II.
Stages of Production
2014
Production Procedures
Escozine for Pets has 4 major production steps.
1.
2.
3.
4.
Stages of Production
2014
Stages of Production
2014
II.
Stages of Production
2014
Stages of Production
2014
Water
Pattern
(2mg/ml)
Target
React. C
Folin dil.
1.0 ml
--
--
5 ml
0.5 ml
0.9 ml
0.1 ml
--
5 ml
0.5 ml
0.8 ml
0.2 ml
--
5 ml
0.5 ml
0.7 ml
0.3 ml
--
5 ml
0.5 ml
0.6 ml
0.4 ml
--
5 ml
0.5 ml
0.7 ml
--
0.3 ml
5 ml
0.5 ml
0.5 ml
--
0.5 ml
5 ml
0.5 ml
Abs.580nm
Steps to be followed:
Stages of Production
2014
Stages of Production
2014
PROG
Lamp
RS
ABS
STEP
RCL
BSTP
STOP
CALL
GOTO
FUNC
Reading
ALFA
%T
REA
CALL
XY
CH
+
X
7
4
1
UV
8
5
2
SCA
N
OPERATING GRADIENT
Time
Flow
%A
Inicial
0
2.00 min
0
0
12.00
min
100
14.00
min
100
44.00
min
100
46.00
min
%B
100
100
100
%C
VIS
9
6
3
Entr
TABLE #: 6
Curve
*
6
6
%D
1
4
7
CLEAR
HOME
2
5
8
0
ENTER
3
6
9
.
Refrigeration:
Once the therapeutic dose is determined and the extraction concentrate is ready for
manufacturing, the container is sealed and placed in a refrigerated environment. The
container is kept in that refrigerated environment for thirty minutes until the venom
reaches a maximum of 12C (52F). At this time, the container will be packed into a
Stages of Production
2014
III.
Stages of Production
2014
Stages of Production
2014
10
Stages of Production
2014
11
IV.
In the next step the bottled and sealed product moves by conveyer belt to the labeling
section where the expiration date and lot number are printed onto the labels. Following
this procedure, the bottles are packed in individual cartons with instructions and a 20-30
ml plastic cup and a 1ml plastic dropper. Next is the packaging process where individual
cartons get inserted into transportation boxes. The bulk version of the product is
transferred into a sealed, refrigerated storage room.
Storage/Refrigeration: The bulk container is stored in a dark, refrigerated environment
at the storage facility which is maintained at a temperature between 12 and 14 C (52F
and 58F) while awaiting shipment.
Quality Control: Individual containers of the final product from each and every batch
are collected for quality control. Microbiological tests and other additional tests are
performed to insure the right concentration of the main ingredient is in each batch. The
therapeutic concentration level is tested by using mass spectrometry analyses; the
results are compared to standardized mass spectrometry readings for the product. No
product is shipped until the batch has undergone testing.
Batch Rejection:
A batch of final product is rejected upon the following conditions:
1. Microbiological Test: If one bottle of final product tests positive for bacterial
contamination, then entire batch is rejected.
Stages of Production
2014
12
DELIVERY TO CUSTOMERS
Stages of Production
2014
13