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Summary
Background In 2000, world leaders agreed on the Millennium Development Goals (MDGs). MDG 4 called for a
two-thirds reduction in the under-5 mortality rate between 1990 and 2015. We aimed to estimate levels and trends in
under-5 mortality for 195 countries from 1990 to 2015 to assess MDG 4 achievement and then intended to project how
various post-2015 targets and observed rates of change will aect the burden of under-5 deaths from 2016 to 2030.
Methods We updated the UN Inter-agency Group for Child Mortality Estimation (UN IGME) database with
5700 country-year datapoints. As of July, 2015, the database contains about 17 000 country-year datapoints for mortality
of children younger than 5 years for 195 countries, and includes all available nationally-representative data from vital
registration systems, population censuses, household surveys, and sample registration systems. We used these data
to generate estimates, with uncertainty intervals, of under-5 (age 04 years) mortality using a Bayesian B-spline biasreduction model (B3 model). This model includes a data model to adjust for systematic biases associated with
dierent types of data sources. To provide insights into the global and regional burden of under-5 deaths associated
with post-2015 targets, we constructed ve scenario-based projections for under-5 mortality from 2016 to 2030 and
estimated national, regional, and global under-5 mortality rates up to 2030 for each scenario.
Results The global under-5 mortality rate has fallen from 906 deaths per 1000 livebirths (90% uncertainty interval
893922) in 1990 to 425 (409456) in 2015. During the same period, the annual number of under-5 deaths
worldwide dropped from 127 million (126 million130 million) to 59 million (57 million64 million). The
global under-5 mortality rate reduced by 53% (5055%) in the past 25 years and therefore missed the MDG 4 target.
Based on point estimates, two regionseast Asia and the Pacic, and Latin America and the Caribbeanachieved
the MDG 4 target. 62 countries achieved the MDG 4 target, of which 24 were low-income and lower-middle income
countries. Between 2016 and 2030, 944 million children are projected to die before the age of 5 years if the 2015
mortality rate remains constant in each country, and 688 million would die if each country continues to reduce its
mortality rate at the pace estimated from 2000 to 2015. If all countries achieve the Sustainable Development Goal of
an under-5 mortality rate of 25 or fewer deaths per 1000 livebirths by 2030, we project 560 million deaths by 2030.
About two-thirds of all sub-Saharan African countries need to accelerate progress to achieve this target.
Published Online
September 9, 2015
http://dx.doi.org/10.1016/
S0140-6736(15)00120-8
See Online/Comment
http://dx.doi.org/10.1016/
S0140-6736(15)00193-2
Division of Data, Research, and
Policy, UNICEF, New York, NY,
USA (D You PhD, L Hug MA,
S Ejdemyr MA, P Idele PhD);
WHO, Geneva, Switzerland
(D Hogan PhD, C Mathers PhD);
United Nations Population
Division, New York, NY, USA
(P Gerland PhD); University of
California, Berkeley, CA, USA
(J R New MA); and Department
of Biostatistics and
Epidemiology, School of Public
Health and Health Sciences,
University of Massachusetts,
Amherst, MA, USA
(L Alkema PhD)
Correspondence to:
Dr Danzhen You, Division of
Data, Research, and Policy,
UNICEF, New York,
NY 10017, USA
dyou@unicef.org
Interpretation Despite substantial progress in reducing child mortality, concerted eorts remain necessary to avoid
preventable under-5 deaths in the coming years and to accelerate progress in improving child survival further. Urgent
actions are needed most in the regions and countries with high under-5 mortality rates, particularly those in
sub-Saharan Africa and south Asia.
Funding None.
Copyright 2015. World Health Organization. Published by Elsevier Ltd/Inc/BV. All rights reserved.
Introduction
The year 2015 is crucial for policy discussions about
child survival, not only because it is the target year for
nal reporting on the Millennium Development Goals
(MDGs), but also because it is the year in which
stakeholders are coming together to agree on the
post-2015 agenda. In 2000, world leaders agreed on the
MDGs and called for a two-thirds reduction in the
under-5 mortality rate (U5MR) between 1990 and
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Research in context
Evidence before this study
Nationally representative high-quality data for mortality of
children younger than 5 years are available at regular time
intervals from vital registration for only about 60 countries.
For the rest of the world, knowledge depends on data from
population censuses, household surveys, and sample
registration systems. All publicly available data for under-5,
infant, and neonatal mortality are compiled annually by the UN
Inter-agency Group for Child Mortality Estimation (UN IGME) to
improve monitoring of progress towards child survival goals
and to enhance the capacity of countries to produce timely
estimates of child mortality. The UN IGME global database
before this study contained about 16 000 observations with
meta-information from 1950 (or earlier) to 2013 available as of
July, 2014. The UN IGME uses this information to produce
annual updates, typically released in September, of neonatal,
infant, and under-5 mortality rates and trends for 195 countries
or areas.
Added value of this study
This study provides estimates of under-5 mortality up to the
Millennium Development Goal (MDG) target year (2015) and
constructs scenario-based projections from 2016 to 2030 to
provide insights into the burden of under-5 deaths in the next
15 years. This study extended the existing UN IGME global
database by including 5700 new or updated observations and
also incorporated updated HIV/AIDS estimates from UNAIDS
and revised population numbers from the UN Population
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Methods
Estimation of under-5 mortality
The UN Inter-agency Group for Child Mortality Estimation
(UN IGME) was established in 2004 to improve
monitoring of progress towards child survival goals and to
enhance the capacity of countries to produce timely
estimates of child mortality. It is led by the UN Childrens
Fund (UNICEF), and includes WHO, UN Population
Division, and World Bank. The group is advised by an
independent technical advisory group of leading experts
in demography and biostatistics. The UN IGME produces
annual updates, usually released in September, of
neonatal, infant, and under-5 mortality levels and trends
for 195 countries or areas. These UN IGME estimates
represent the most up-to-date comprehensive information
on child mortality and provide a basis for assessing
progress and reaching consensus for action.16
The UN IGME estimation process aims to compile all
available nationally-representative empirical data relevant
to child mortality, which includes to access various data
sources, assess data quality, recalculate harmonised data
inputs, and make adjustments, if needed, through
standard methods, and then to t statistical models to
these data to generate smoothed time series and
uncertainty ranges and extrapolate to a target year.10
Below we summarise our database and analysis
approach; details about data sources and methods used
to generate mortality rates and number of deaths are
available online (appendix pp 211).
Nationally-representative data of under-5 mortality
can be derived from several dierent sources, including
civil registration, censuses, and sample surveys.
Demographic surveillance sites and hospital data are
excluded because they are rarely nationally representative. The preferred source of data is a civil
registration system that records births and deaths on a
continuous basis. If registration is complete and the
system functions eciently, then the resulting estimates
will be accurate and timely. However, most low-income
and middle-income countries do not have well
functioning civil registration systems, and household
surveys and periodic population censuses have become
the primary source of data for child mortality. However,
these data often have (sometimes substantial) sampling
or non-sampling errors.15
The UN IGME web portal hosts the full set of empirical
data. The 2015 update to the UN IGME database included
more than 5700 new or updated country-year datapoints
for U5MR from more than 130 series. The database, as of
July, 2015, contains 17 000 country-year datapoints from
more than 1500 series across 195 countries from 1990
(or earlier) to 2015.
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1970
1990
2015
Decrease 1990
to 2015 (%)
1970
1990
2015
Decrease 1990
to 2015 (%)
1449
(14061500)
906
(893922)
425
(409456)
53%
(5055)
172
(167179)
127
(126130)
59
(5764)
53%
(5055)
Africa
2404
(23352497)
1641
(16111676)
763
(713851)
54%
(4857)
38
(3740)
42
(4142)
31
(2934)
26%
(1731)
52%
(4955)
Sub-Saharan Africa
2443
(23592557)
1802
(17681842)
831
(775930)
54%
(4857)
32
(3033)
39
(3840)
29
(2733)
24%
(1429)
50%
(4753)
2127
(20112267)
1665
(16241714)
665
(604781)
60%
(5364)
13
(1314)
17
(1718)
11
(1013)
39%
(2844)
18%
(1621)
2755
(26232927)
1984
(19252049)
987
(8821138)
50%
(4356)
17
(1618)
20
(2021)
18
(1621)
12%
(222)
30%
(2733)
1995
(19342066)
710
(694730)
289
(266321)
59%
(5563)
12
(1213)
07
(0607)
03
(0304)
51%
(4555)
5%
(56)
Asia
1537
(14691615)
903
(882927)
364
(339395)
60%
(5663)
109
(103115)
72
(7074)
24
(2226)
67%
(6469)
41%
(3743)
South Asia
2132
(20592212)
1293
(12611326)
525
(480578)
59%
(5563)
58
(5661)
47
(4648)
19
(1721)
60%
(5664)
31%
(2934)
1164
(10571283)
583
(554618)
178
(164197)
69%
(6672)
50
(4555)
25
(2427)
05
(0506)
79%
(7681)
9%
(810)
1196
(11631234)
538
(522557)
179
(171193)
67%
(6469)
12
(1213)
06
(0607)
02
(0202)
69%
(6671)
3%
(34)
CEE/CIS
966
(9071035)
476
(462491)
171
(148220)
64%
(5469)
06
(0607)
04
(0304)
01
(0101)
69%
(6074)
2%
(22)
Other countries
245
(243246)
104
(103105)
48
(4553)
54%
(4957)
03
(0303)
01
(0101)
01
(0001)
56%
(5260)
1%
(11)
Low income
2566
(24642695)
1872
(18351916)
761
(711852)
59%
(5562)
23
(2224)
26
(2526)
17
(1619)
35%
(2739)
28%
(2631)
2002
(19542060)
1195
(11741218)
528
(493577)
56%
(5259)
90
(8893)
72
(7173)
35
(3338)
51%
(4755)
59%
(5661)
1171
(10701285)
554
(528584)
191
(170228)
66%
(5970)
55
(5061)
27
(2629)
07
(0608)
75%
(7078)
11%
(1013)
High income
324
(313337)
156
(153159)
68
(6475)
56%
(5259)
06
(0506)
03
(0303)
01
(0101)
59%
(5561)
2%
(22)
World
Share of total
deaths
worldwide in
2015 (%)
By region
By income group
For regional classication, including a list of countries in Other countries, see appendix pp 1213. Income group classication is from the World Bank (appendix pp 1314). CEE/CIS=central and eastern Europe
and Commonwealth of Independent States.
Table 1: Global and regional under-5 mortality rates and number of under-5 deaths, with 90% uncertainty intervals
Results
In 2015, the global U5MR is 425 (90% UI 409456)
deaths per 1000 livebirths and the estimated
number of under-5 deaths is 59 million (90% UI
57 million64 million; table 1). In total, an estimated
2363 million (2337 million2402 million) children died
before their fth birthday between 1990 and 2015.
Wide disparities in mortality rates exist across regions
(gure 1). West and central Africa continues to have the
highest U5MR worldwide with a U5MR of 987
(90% UI 8821138) deaths per 1000 livebirths, almost
15 times higher than the average U5MR in high-income
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West and
central Africa
Eastern and
southern Africa
South Asia
East Asia
and the Pacific
CEE/CIS
Other
countries
200
150
100
50
19
9
19 0
9
20 5
0
20 0
0
20 5
1
20 0
15
19
9
19 0
9
20 5
0
20 0
0
20 5
1
20 0
15
19
9
19 0
9
20 5
0
20 0
0
20 5
1
20 0
15
19
9
19 0
9
20 5
0
20 0
0
20 5
1
20 0
15
19
9
19 0
9
20 5
0
20 0
0
20 5
1
20 0
15
19
9
19 0
9
20 5
00
20
0
20 5
1
20 0
15
19
9
19 0
9
20 5
00
20
0
20 5
1
20 0
15
19
9
19 0
9
20 5
00
20
0
20 5
1
20 0
15
0
Year
Year
Year
Year
Year
Year
Year
Year
Figure 1: Trends in the under-5 mortality rate and number of under-5 deaths, with 90% uncertainty intervals, by region
CEE/CIS=central and eastern Europe/Commonwealth of Independent States. See appendix pp 1213 for regional classication, including for those included in Other countries.
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A
ARR in under-5 mortality (%)
World
100
75
B
197090
19902000
200015
World
50
Eastern and
southern
25
Africa
0
West and
central
25
Africa
Middle East and north Africa
100
South Asia
Middle East
and north
75
Africa
50
East Asia
and the Pacic
25
0
South Asia
25
100
Latin America
Latin America and the Caribbean
CEE/CIS
and the
Other countries
Caribbean
75
CEE/CIS
50
Other
countries
25
0
Year
Year
20
10
20
00
80
19
90
19
70
19
20
10
20
00
80
70
19
90
19
19
20
10
20
00
80
19
90
19
19
70
25
Year
Figure 3: Annual (A) and average (B) ARR in under-5 mortality rate (90% UI), worldwide and by region
The vertical dotted lines at 1990 represent the starting year of the Millennium Development Goals period. Note that spikes in ARR are due to crisis mortality: the ARR
for Latin America and the Caribbean in 2010 is aected by the earthquake in Haiti. The ARR in east Asia and the Pacic is aected by the southeast Asian tsunami in
2004 and the Myanmar cyclone in 2008. The ARR in eastern and southern Africa around 1994 is aected by the Rwanda genocide. Regional estimates CEE/CIS are
not presented before 1980 due to lack of underlying data in countries in the region. Regional classication can be found on pp 1214 of the appendix. ARR=annual
rate of reduction. CEE/CIS=central and eastern Europe/Commonwealth of Independent States.
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472
425
40
30
262
20
172
132
10
61
0
66
59
36
24
18
08
0
2015
2020
2025
Year
Scenario 1: no change from 2015 mortality rate
Scenario 2: current trends
Scenario 3: best regional performer
Scenario 4: SDG target
Scenario 5: average mortality rate of HIC by 2030
2030
Figure 4: Projected global under-5 mortality rate and the number of under-5
deaths under various scenarios, 201530
SDG=sustainable development goals. HIC=high-income country.
Projected total
number of
deaths
(millions)
2020
2025
2030
2020
2025
2030
442
458
472
62
64
66
201630
944
362
308
262
50
42
36
688
285
194
132
39
26
18
494
313
232
172
43
32
24
560
216
113
61
30
15
08
354
Table 2: Projected global under-5 mortality rate and under-5 deaths under dierent scenarios
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Discussion
Remarkable progress has been made worldwide to
improve child survival over the past 25 years. The global
U5MR declined by 53% and the number of under-5 deaths
dropped from 127 million in 1990 to 59 million in 2015.
All regions have reduced their U5MR at least by half and
progress has accelerated worldwide: the global ARR has
steadily doubled. In sub-Saharan Africa (the region with
the highest U5MR in the world) the ARR increased from
16% in the 1990s to 41% in 200015. The recent trend is
especially encouraging in eastern and southern Africa,
which had an average ARR of almost 5% in 200015.
Low-income country
Lower-middle-income country
Upper-middle-income country
High-income country
Angola
12
Chad
Somalia
Nigeria
Democratic
Republic of
the Congo
10
Under-5 deaths
(in millions)
0
Sierra Leone
Mali
02
04
Pakistan
08
12
Ethiopia
India
Tanzania
4
Bangladesh
2
Indonesia
China
0
0
10
12
Figure 5: The ARR needed to meet the SDG target of an under-5 mortality rate of 25 deaths per
1000 livebirths by 2030 compared with the ARR observed in 200015
For countries that have already reached the target, the required ARR is set as zero. Each bubble represents a
country, with the size of the bubble representing the number of under-5 deaths in 2015. Labelled countries are the
ten with the largest number of deaths and those with the highest ARR needed. ARR=annual rate of reduction.
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25
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