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v.11/15
AVERYIMPORTANTANDHEARTFELTDISCLAIMER
Atthetimeofthiswriting,thenootropicsdiscussedinthisguidearelegaltopurchasewithinthe
UnitedStates.Thisdoesnotmeantheyshouldbeconsumedwithoutfirstconsultingwitha
physician.Adrugpurchasedlegally,overthecounter,doesnotnecessarilymeanitissafeto
usewithoutprofessionalsupervision.Iamnotadoctor/physician,Iamjustsomeguywritingan
ebookontheInternet.Pleaseneverriskyoursafety.
Thisguideistobeusedforeducationalandinformationalpurposesonly.Thisguideisnot
meanttobeused,norshoulditbeused,todiagnoseortreatanymedicalcondition.Forthe
diagnosisortreatmentofanymedicalcondition,consultyourownphysician.Thepublisherand
authorarenotresponsibleforanyspecifichealthorallergyneedsthatmayrequiremedical
supervisionandarenotliableforanydamagesornegativeconsequencesfromanytreatment,
action,application,orpreparationtoanypersonreadingorfollowingtheinformationinthis
guide.
PREFACE
Firstdevelopedinthe1950sintheUnitedStates,SmartDrugs(alsocommonlyreferredtoas
Nootropics)inspiredagenerationofcreativemindslikeMichaelHutchison,BillHarris,andDave
Asprey.ThewordNootropicswascoinedbyPsychologistandChemistC.C.Giurgeaand
comesfromtheGreeknous,ormind,andtrepeinmeaningtobend.)
Resurginginuseandpopularitywithinthepastfiveyears(GoogleTrendssuggestinga1000%
increaseinsearchessince2011,)SmartDrugsnotonlyhavebeenrepopularized,butnew
organizationsareformingtodesignatebestqualityandnewcombinationstomeetthedemand.
Anewgenerationsrediscoveryofanoldtechnologyhasalreadyledtonewadvancesinthis
field.
MyuseofSmartDrugsbeganin2008.Ayearprior,IwasdiagnosedwithchronicLymedisease
aftertraversingthewoodsinNewHampshire.Lymediseaseisaninterestingexperienceasit
generallyaffectspeopledifferently.Somepeoplehavechronicjointpain,somehave
inflammationoftheGIsystem,somelosemovementintheirlimbs,andevenalloftheabove.
Forme,thespirochetalbacterialchosemybrain.Thecorkscrewshapedcrittersdugtheirway
intomycerebraltissuesand,alongwithagreatsenseofchronicfatigue,Iexperiencedawide
varietyofmentalperformanceissuesforthenexttwoyears,withsomelingeringdefectsIstill
battletothisday.ItisforthisreasonIbeganseekinginformationtoimprovebrainhealthby
alteringmyphysiologytoincreasementalperformance.Thiswasmyfirstseriousattemptat
whatisnowknownasbiohacking.
Whilelongtermantibiotictreatmentwasthesolutionto80%ofmyabnormalsubjective
experiences,Iexperimented,underaphysician'scare,withdrugstohelplessenthenegative
experiences.TheveryfirstofwhatmaybedeemedasaSmartDrugisModafinil.
Today,IuseSmartDrugs(amongotherthingssuchasbrainmindmachines,meditation,diet,
andexercise,)toassistinreclaimingthefinal20%ofmymentalpower,soImaylivethelifeI
desire.
Ingraduateschool,Istudiedtranspersonalpsychology,whichmapsalotofsubjectiveterritory
havingtodowiththeexperienceoftheself.SmartDrugusewithinthiscontextfirstbecamea
seriousacademicpursuitofminein2013.
ThepathofSmartDruguseisntforeveryone,however,Isuspect,sinceyourereadingthese
words,youhaveenoughinteresttoexplorethisoptiontoseeifitsrightforyou.
Biohackersunite,
SteveCronin
WHATARESMARTDRUGS?
SmartDrugsrefertoexogenoussubstances(sometimespharmaceuticals)inthecommonforms
ofcapsules,tablets,liquids,andbulkpowders,thatchangetheelectrochemicalactivityinthe
brain.Atpresentday,objectivemeasurableslikeelectricbrainwaves,chemical
neurotransmitters,andeventoolsformappingbloodflow,areourbestbetindeterminingand
predictingwhatacorrelatedsubjectiveexperiencewhileonthedrugmightbe.
Generally,SmartDrugsarethoughttoaffecttwomajoraspectsofthebrain(amongothersas
welllikebloodflow:)brainwavesandneurotransmitters.Itisimportanttonotethattheexact
mechanismofactionwhichsmartdrugs(andmanypharmaceuticaldrugsforthatmatter)are
somewhatunknown.Becauseofthis,individualresearchandeducationisamustbeforesmart
druguse,andthisbookisintendedtoactasaplatformforthateducation.Thatbeingsaid,even
withmyexpertise,Istillonlyusesmartdrugswhileunderthecareofaphysician,andyou
shouldtoo!
Brainwavesareidentifiedpatternsofelectricalactivity.Theyaremeasuredbyan
electroencephalogram(EEGmachine.)Generally,adominantbrainwave,oracombinationof
dominantbrainwaves,incertainregionsofthebrainareassociatedwithsubjectivefeelingsof
certainmentalstates.Forexample:
Gamma(30+Hz)HeightenedPerceptions
Beta(1430Hz)NormalWakingState
Alpha(913Hz)RelaxedFocus
Theta(48Hz)DeepRelaxation,IncreasedMentalImagery
Delta(13Hz)DeepSleep
Epsilon(0.250.5Hz)ExtremelyDeepMeditation,PossibleNonDualAwareness
Neurotransmittersarechemicalswithinthebrainthatgenerallytravelasmessengercellswith
brainwaves.
Generallyspeaking,anincreaseofaspecificneurotransmitteristhoughttoincreasethe
correlatedsubjectiveeffect.However,thereexistsathresholdinwhichfurtherincreasesfall
victimtoaslewofnegativesideeffects.Whiletheaverageperson(likemyself)isunableto
haveaccesstotheresourcestodeterminewhatchemicaldeficitsordominantstheymayhave,
therearesomeprimitivetoolsavailable,liketheBravermanAssessment.
Somecommonneurotransmittersandtheirpresumptive,subjectiveassociations:
AcetylcholineFocus,Learning,Memory
DopaminePleasure,Movement,Addiction
SeretoninMood,Wellbeing
NoepiniephrineMotivation,Attention
GABASenseofCalm,Focus,AntiAnxiety
Recently,asdocumentedbynewsoutletslikeVICE&WIRED,smartdrugshavereentered
popularculture.LikelythankstofilmslikeLimitlessandLucy,theyarepresentedthroughthe
perspectiveofamagical,miracle,andfixallsolution.Unfortunately,theseideasaremyths
propagatedbygroupsandindividualswhichimbueasenseofmysteryandintrigueintothe
sensationalizedmindsofthosereadingaboutthedrugs.Unfortunately,thisattributionofa
magicpillhasverylittlebasisinrealityandoften,inmyexperiencewithnootropicsandthe
nootropicscommunity,leadstoextraordinaryexpectationswhichareneverfulfilled.Mostof
thesepublicationsrefertoaprescriptiononlydrugintheUnitedStates,whichhasofflabeluses
forenergyandfocus,calledModafinil.
WhileModafinilisaverypowerfulsmartdrug,itseffects(likemostsmartdrugs)areverysubtle.
Successisusuallyrealizedafterdailyuseandtracking,andafteradrugisremovedfromones
regimine.Peoplethenrealizethelackofbrainpowerafterstoppingthesmartdruguse,rather
thananimmediaterushofbrainpowerwheninitiatingfirstuse.Thatbeingsaid,everyoneis
differentinbothaphysiologicalsenseandinthemannerthroughwhichweinterpretnew
experiences.
Whilethelimitsofsmartdrugsformanypeoplearethosesubtleexperiences,theirusesvary
frominducingstatesofconsciousnesslikefocus,tocultivatingabroadlydefinedskilllike
creativity.Whiletherescurrentlynotasmartdrugforeverypotentialskillknowntoman,theres
alotofclaimsfloatingaroundwhicharewaitingtobeexplained.Thatbeingsaid,thefollowing
hasbeengenerallywelldocumented:differentsmartdrugsinducedifferentphysiological
changeswithinthebody(includingthetwomajorcomponentsdiscussedearlier,brainwaves
andneurotransmitters.)
Drugs:Aniracetam,Piracetam,Choline,DMAE
AffectedNeurotransmitter:Acetylcholine
PresumptiveAffectedBrainWaves:Alpha,Theta
PossibleSubjectiveEffects:Increasedsenseoffocus
Thisleadstotheideaofstacking:thatis,combiningtwoormorenootropicsubstancestogether
inordertoeitheramplify,orgeneratenew,desiredeffects.Acommonsupplementtostackwith
somethinglikeaniracetamorpiracetamischoline,whichalsoactsasaprecursorto
acetylcholine.Toomuchofthisparticularprecursor,however,cansometimesleadto
undesirablesideeffectslikeheadaches.Again,beforeingestingthesenootropics,professional
guidancefromaphysicianisstronglyrecommended.Somethingresemblingtheaforementioned
stack,iswhatyou'llbelearningtomakeinthisguide.
HOWTOMAKEYOUROWNSMARTDRUGS
Whatyou'llneed:
1.Piracetam
https://newstarnootropics.com/piracetam
Piracetamisanootropicdevelopedin1964thatisthoughttoincreaseacetylcholinelevelsinthe
brainandmaygenerateasubjectivesenseoffocus.
NewStarNootropicsPiracetamVideoReview:
https://www.youtube.com/watch?v=me_HkI18IlA
2.Choline
http://purebulk.com/cholinelbitartrate/
Cholineisaprecursortoacetylcholineinthebrain,whichisthoughttocreateasubjectivesense
ofincreasedfocus.
PureBulkCholineVideoReview:
https://www.youtube.com/watch?v=5jTPhv7Liis
3DMAE
http://purebulk.com/dmaebitartratepowder/
DMAEisalsoaprecursortoacetylcholineinthebrain,whichisthoughttocreateasubjective
senseofincreasedfocus.
PureBulkDMAEVideoReview:
https://www.youtube.com/watch?v=VH6zXl9l9nE
4.ElectronicScale
5.Blender
(withmixingbowl)
6.CapsuleMachine
(Size0)andEmptySize0Capsules
http://purebulk.com/0capsulemachineemptygelcapsvegetariancapsules/
http://purebulk.com/cleargelatin0capsules/
StepOne:
Aftergatheringyourmaterials,measurethefollowingamountsofnootropicsandpourthe
measuredamountsintoyourblender.
Piracetam(70grams)
Choline(30grams)
DMAE(30grams)
Youmayadjust,orchange,theaboveratioasyouseefit,personalizedtoyourownresearch.
StepTwo:
Blendtheingredientstogetherforabout3minutes.Becarefultotakebreakswhennecessaryif
yourparticularblenderheatsquickly.Eventually,youllseesomelacing/rippleeffectsinthe
powder.Thisishowyoullknoweverythingisbeingmixedthoroughly.Ifnecessary,youmay
needtopausetheblendingprocessandslightlyshakeyourblenderifyouringredientsattractto
theedgesofthevesselanddonotmixproperly.
StepThree:
Beforetakingthelidfromyourblender,takecaretoallowyouringredientstosettleforseveral
minutesinordertoavoidexcessamountsofpowderreleasingintotheair.Pouryournewly
blendedmixtureintoyourmixingbowl.
StepFour:
SetupyourCapsuleMachineusingitsincludedinstructions.Youllwanttopullapartyourempty
capsuleandplacethelongendintothebaseofthemachineandtheshortendsintothetopof
themachineasseenbelow.
(Baseofmachine)
(TopofMachine)
StepFive:
Takecaretopouraportionofyourblendedingredientsintothebaseofthemachineaspictures
below.
StepSix:
UsethecardincludedwiththeCapsulemachinetoevenlydistributeyouringredientsas
picturedbelow.
StepSeven:
Repeatstepsfiveandsix,thenproceedtostepeight.
StepEight:
Usingtheparticularinstructionsincludedwithyourcapsulemachine,fitthetopofthemachine
(picturedabove)overthebaseofthemachine(alsopicturedabove)andpressfirmly.The
capsuleswillformtogether.Uponliftingthetopofthemachine,revealingyournewlymade
capsules,youllbeabletoreleasethemintoacontainerofyourchoosing.
Congratulations!Youvenowcreatedyourownnootropicstack!
Whatistheweightofeachingredientineachcapsule?
1.Recalltheoriginalmeasurements:
Piracetam(70grams)
Choline(30grams)
DMAE(30grams)
TOTAL(130grams)
2.Dividetheamountofeachingredientby130grams.Forexample,70gramsofpiracetam
dividedby130grams(thetotalamount)equalsabout0.54grams.
70gPiracetam/130g=0.54gofPiracetam
30gCholine/130g=0.23gofCholine
30gDMAE/130g=0.23gofDMAE
3.Multiplythenumbersretrievedinsteptwobytheweightattainablebytheemptycapsules.
Size0capsulesholdabout500700mg.Forexample,0.53gramsmultipliedby700milligrams
equals371milligrams.Thisistheamountofpiracetamineachcapsule.
0.54gPiracetam*700mg=378mgofPiracetamineachcapsule
0.23gCholine*700mg=161mgofCholineineachcapsule
0.23gDMAE*700mg=161mgofDMAEineachcapsule
FINALTHOUGHTS
Thereyouhaveit!Younowhaveabasicknowledgefordesigningandencapsulatingyourown
personalnootropicstacks.Pleasetakecaretoperformallofyourownresearchandyourown
arithmetic.DoNOTblindlyfollowinganyformulas(includingmine)withouttriplecheckingyour
ownworkandtheworkofyoursource.Beforeactuallyingestinganynootropic(whetherone
youdesignorpurchasefromsomeoneelse,)pleaseseektheadviceofaphysician.Iamnota
Doctor,IamjustsomeguywritinganebookontheInternet.Idonotthinkitsagoodideato
takedrugs(evenlegalones)thatcanpotentiallybeharmfulwithoutfirstconsultingaphysician.
Pleaseneverriskyoursafety.