In my Windows: I have removed the content from "%localappdata%\Xamarin\MonoT ouch." In Mac terminal: Remove the authorized_keys Mac file ("rm /Users/macmini2/.s sh/authorized_keys" in my case) In Mac terminal: chmod g-w /Users/macmini2/ In Mac terminal: chmod 700 /Users/macmini2/.ssh/ In Mac terminal: Create a empty file: /Users/macmini2/.ssh/authorized_keys ( with vim, for example) In Mac terminal: chmod 600 /Users/macmini2/.ssh/authorized_keys On Visual Studio: Login with Xamarin Mac Agent On Visual Studio: Run the application with [Debug] - [iPhoneSimulator] - [iP hone 5 iOS 8.1] And finally, the simulator runs on Mac computer.